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    COMPARATIVE RESEARCHES OF FRACTURES OF HIGH-STRENGTH CAST IRON IN THE AS-CAST AND DEFORMED STATE by A. I. Pokrovsky, I. N. Khrol

    Published 2016-01-01
    Subjects: “…the results of comparative studies of fracture surfaces of high-strength cast iron in the as-cast state and after hot direct extrusion through an aperture of a conical die are presented. the shape change of graphite inclusions and components of the metal matrix is examined with increasing the reduction ratio from 0 (as-cast state) to 80%. for the fist time, using the electrochemical etching of the metal matrix of the cast iron, it is demonstrated experimentally that at plastic deformation the ductile flow of graphite inclusions occurs without fracturing of the latter. the surface morphology of a deformed graphite inclusion is revealed. it is shown that inside the inclusion the strain is distributed non-uniformly: the peripheral zones are deformed to a larger extent while the central part may retain its original radial structure. the fact that the most part of graphite inclusions on the fracture surface of the deformed cast iron appeared undamaged (very small amount of fractured inclusions was observed) testifies against the common opinion that graphite acts as a crack nucleation site. a hypothesis is put forward that the crack nucleates in the metal matrix, presumably at the pearlite/ferrite interface, and propagates from one graphite inclusion to another rounding but not damaging the latter.…”
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    I-SPY COVID adaptive platform trial for COVID-19 acute respiratory failure: rationale, design and operations by Carolyn S Calfee, Michael A Matthay, Paul Henderson, Martin Eklund, Laura J Esserman, Chirag Patel, Angela Haczku, Michelle Jung, Tony Oliver, Alessio Crippa, Andrea Discacciati, Kathleen D Liu, Ellen L Burnham, Nuala J Meyer, Fady A Youssef, Derek W Russell, Julie Lang, Kevin W Gibbs, Daniel C Files, Sheetal Gandotra, Purnema Madahar, Nathan K Cobb, Timothy E Albertson, Rajiv Sonti, John P Reilly, Alejandra Jauregui, Iván García, Luis E Huerta, Daniel Clark Files, Neil R Aggarwal, Adam L Asare, Jeremy R Beitler, Paul A Berger, George Cimino, Melissa H Coleman, Paul T Henderson, Caroline A G Ittner, Kashif T Khan, Jonathan L Koff, Mary LaRose, Joe Levitt, Ruixiao Lu, Jeffrey D McKeehan, Karl W Thomas, Aaron M Mittel, Albert F Yen, Alexis E Suarez, Alexis L Serra, Alpesh N Amin, Amanda Rosen, Amy L Dzierba, Anna D Barker, Ariel R Weisman, Brian M Daniel, Brian M Morrissey, Caroline AG Ittner, Chayse Jones, Christina Creel-Bulos, Christina M Angelucci, Diana Ng, Fredy Chaparro-Rojas, Gavin H Harris, Harsh V Barot, Heny Su, Jacqueline B Sutter, Jamal Dodin, Jerry S Lee, John Kazianis, Joshua F Detelich, Julie E Lang, Justin Muir, Katarzyna Gosek, Katherine L Nugent, Kimberly Yee, Laura G Rodrigues, Laura R Macias, Lindsey A Orr, Lindsie L Boerger, Lissette Rosario-Remigio, Lucia Kufa, Maged Tanios, Maria B Reyes, Max W Adelman, Maya M Juarez, Michelle Meyers, Mitchell P Sternlieb, Neil Aggarwal, Nilam S Mangalmurti, Patrice Jones, Paul L Saban, Peter S Marshall, Philiip A Robinson, Philip Yang, Rahul Nair, Richard Anthony Lee, Richard G Wunderink, Romina Wahab, Roxana A Lupu, Santhi I Kumar, Sara C Auld, Scott Fields, Se Fum Wong, Skyler J Pearson, Spencer Whealon, Timothy F Obermiller, Anita Darmanian, John Schicchi, Esmeralda Martinez, Farjad Sarafian, Julie Nguyen, Bethany Weiler-Lisowski, Jaime Wyatt, Daniel Blevins, Marylee Melendrez, Brenda Lopez, Hiwet Tzehaie, Omowunmi Amosu, Austin Simonson, Erin Hardy, Brett Lindgren, Gregory Peterfreund, Leigha Landreth, Lisa Parks

    Published 2022-06-01
    “…Enrolled patients are randomised to receive one of up to four investigational agents or a control and are evaluated for a family of two primary outcomes—time to recovery and mortality. …”
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  17. 2857

    Clinical management of community-acquired meningitis in adults in the UK and Ireland in 2017: a retrospective cohort study on behalf of the National Infection Trainees Collaborativ... by Amy Robinson, Kamaljit Khalsa, Arjun Chandna, John Bowen, Viva Levee, Jan Coebergh, Tom Solomon, Clive Graham, David Turner, Robert Tilley, Tim Jones, Susan Hopkins, Matthew Stevens, Daniel White, Celestine Eshiwe, Anna Goodman, Ramandeep Singh, Robert S Heyderman, Nicholas Davies, Joseph Thompson, Ed Moran, Martin Williams, Rhea O’Regan, Simon Tiberi, Jonathan Lambourne, Naomi Bulteel, Susan Larkin, Ruth McEwen, Hassan Paraiso, Aarti Shah, Martin Wiselka, Sylviane Defres, Ernest Mutengesa, Maria Krutikov, Ruth Owen, David Griffith, David Harvey, Trupti Patel, Brendan Davies, Emma Mclean, Joanna Allen, Ali Khan, Alastair Miller, Ashutosh Deshpande, Christopher Green, Lewis Jones, Mark Melzer, Fiona McGill, Amanda Fife, Nimal Wickramasinghe, Stephanie Harris, Ewan Hunter, Jayne Ellis, Benedict Rogers, Imogen Fordham, Elen Vink, Victoria Ward, Anna Smith, Andrew Rosser, Alison Muir, Ken Woodhouse, John Shone, Iain Crossingham, Ryan Jayesinghe, Eavan Muldoon, Avneet Shahi, Terry John Evans, Jeremy Wong, Eloisa MacLachlan, Amy Chue, Karishma Gokani, Katherine Ajdukiewicz, Lucinda Barrett, Frances Edwards, Adam Usher, Mairi McLeod, Su su Htwe, Grace Duane, Nicholas Wong, Jennifer Poyner, Jenni Crane, Ollie Lloyd, Emma Chisholm, Ildiko Kustos, Sam Sutton, M. Estee Torok, Isobel Ramsay, Monica Ivan, Joshua York, Jennifer Ansett, Maithili Varadarajan, Priya Sekhon, James Cruise, Shivani Kanabar, Mirella Ling, Charlotte Milne, Jayanta Sarma, Aline Wilson, Lynn Urquhart, Sahar Eldirdiri, Leila White, Jody Aberdein, Phillip Simpson, Hnin Hay Mar, Keying Tan, Eint Shwe Zin thein, Mahmoud Aziz, Anthony Cadwgan, Natasha Weston, Salman Zeb, Angela Houston, Louise Wootton, Iona Willingham, Aimee Johnson, Ashley Horsley, Eamonn Trainor, Olivier Gaillemin, Nicholas J Norton, Katie Cheung, Megan Duxbury, Emilie Bellhouse, Helena Brezovjakova, Kanitkar Tanmay, Alexsander Dawidziuk, Razan Saman, Hugh Adler, Elshadai Ejere, Yiwen Soo, Wendy Beadles, Heather Sturgeon, Brodie Cameron, David Chadwick Ben Tomlinson, Claire McGoldrick, Katie McDowell, Mpho Molosiwa, Katherine FlackAdrian Kennedy, Phoebe Cross, Fay Perry, Vithusha Inpadhas, Sarathy Selvam, Vhairi Bateman, Henry Wu, Monika Pasztor, Ajanthiha Karunakaran, Basma Soliman, Andrew Blanshard, Harish Reddy, Helen Chesterfield, Ben Schroeder, Tee Keat Teoh, Sathyavani Subbarao, Caryn RosmarinLucy Bell, Emma McGuire, Robert Serafino, Ishaan Bhide, Karanjeet Sagoo, Indran Balakrishnan, Kajal Patel, Barzo Faris, Graeme Calver, Ricky Singh, Hazel Sanghvi, Mohamed Eltayeb, Rathur Haris

    Published 2022-07-01
    “…Diagnostics and therapeutics should be targeted for quality improvement strategies. Work should be done to improve the impact of guidelines, understand why they are not followed and, once published, ensure they translate into changed practice.…”
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  18. 2858

    Current Status and Future Prospects of the SNO+ Experiment by S. Andringa, E. Arushanova, S. Asahi, M. Askins, D. J. Auty, A. R. Back, Z. Barnard, N. Barros, E. W. Beier, A. Bialek, S. D. Biller, E. Blucher, R. Bonventre, D. Braid, E. Caden, E. Callaghan, J. Caravaca, J. Carvalho, L. Cavalli, D. Chauhan, M. Chen, O. Chkvorets, K. Clark, B. Cleveland, I. T. Coulter, D. Cressy, X. Dai, C. Darrach, B. Davis-Purcell, R. Deen, M. M. Depatie, F. Descamps, F. Di Lodovico, N. Duhaime, F. Duncan, J. Dunger, E. Falk, N. Fatemighomi, R. Ford, P. Gorel, C. Grant, S. Grullon, E. Guillian, A. L. Hallin, D. Hallman, S. Hans, J. Hartnell, P. Harvey, M. Hedayatipour, W. J. Heintzelman, R. L. Helmer, B. Hreljac, J. Hu, T. Iida, C. M. Jackson, N. A. Jelley, C. Jillings, C. Jones, P. G. Jones, K. Kamdin, T. Kaptanoglu, J. Kaspar, P. Keener, P. Khaghani, L. Kippenbrock, J. R. Klein, R. Knapik, J. N. Kofron, L. L. Kormos, S. Korte, C. Kraus, C. B. Krauss, K. Labe, I. Lam, C. Lan, B. J. Land, S. Langrock, A. LaTorre, I. Lawson, G. M. Lefeuvre, E. J. Leming, J. Lidgard, X. Liu, Y. Liu, V. Lozza, S. Maguire, A. Maio, K. Majumdar, S. Manecki, J. Maneira, E. Marzec, A. Mastbaum, N. McCauley, A. B. McDonald, J. E. McMillan, P. Mekarski, C. Miller, Y. Mohan, E. Mony, M. J. Mottram, V. Novikov, H. M. O’Keeffe, E. O’Sullivan, G. D. Orebi Gann, M. J. Parnell, S. J. M. Peeters, T. Pershing, Z. Petriw, G. Prior, J. C. Prouty, S. Quirk, A. Reichold, A. Robertson, J. Rose, R. Rosero, P. M. Rost, J. Rumleskie, M. A. Schumaker, M. H. Schwendener, D. Scislowski, J. Secrest, M. Seddighin, L. Segui, S. Seibert, T. Shantz, T. M. Shokair, L. Sibley, J. R. Sinclair, K. Singh, P. Skensved, A. Sörensen, T. Sonley, R. Stainforth, M. Strait, M. I. Stringer, R. Svoboda, J. Tatar, L. Tian, N. Tolich, J. Tseng, H. W. C. Tseung, R. Van Berg, E. Vázquez-Jáuregui, C. Virtue, B. von Krosigk, J. M. G. Walker, M. Walker, O. Wasalski, J. Waterfield, R. F. White, J. R. Wilson, T. J. Winchester, A. Wright, M. Yeh, T. Zhao, K. Zuber

    Published 2016-01-01
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