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17321
Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders
Published 2025-02-01Get full text
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17322
Exploring coupling effects of rainfall and surface roughness on the sheet flow velocity
Published 2025-03-01“…Raindrop impact and underlying surface conditions can affect the SF velocity by changing the velocity profile. However, since this information is rarely known, the estimation of SF velocity is inaccurate. …”
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Serine/threonine protein kinase mediates rifampicin resistance in Brucella melitensis through interacting with ribosomal protein RpsD and affecting antioxidant capacity
Published 2025-01-01“…Moreover, co-immunoprecipitation revealed that STPK could efficiently interact with the ribosomal protein RpsD, possibly altering protein translation and riboswitch expression. These findings demonstrate that the STPK gene mediates resistance by regulating sulfur metabolism to counteract the reactive oxygen species induced by rifampicin. …”
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17325
Assessing the relationships of 1,400 blood metabolites with abdominal aortic aneurysm: a Mendelian randomization study
Published 2025-01-01“…In contrast, the top five metabolites that were linked to a reduced risk of AAA included Uridine to pseudouridine ratio, Octadecanedioate, Phosphate to oleoyl-linoleoyl-glycerol (18:1 to 18:2) [2] ratio, 1-(1-enyl-palmitoyl)-GPE (p-16:0), and 1-stearoyl-GPG (18:0).ConclusionAmong the 1,400 blood metabolites, we identified 17 known metabolites, 7 unknown metabolites, and 5 metabolite ratios associated with AAA. …”
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Gegen Qinlian Decoction Attenuates Colitis-Associated Colorectal Cancer via Suppressing TLR4 Signaling Pathway Based on Network Pharmacology and In Vivo/In Vitro Experimental Valid...
Published 2024-12-01“…The protein levels of TLR4 signaling pathway were assessed by western blotting analysis. Enzyme-linked immunosorbent assay measured IL-1β, IL-6, and TNF-α levels. …”
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17329
MiR-4298 and lncKRTAP5-6-3 regulated Cathepsin D expression through ERK-MAPK signaling pathway in chronic UVB-damaged HaCaT cells
Published 2025-01-01“…In this study, we investigated the expression changes and interactions between miR4298 and lncKRTAP5-6-3 in chronically UVB-damaged human keratinocyte cell line (HaCaT) cells and explored miR4298-MAPK/ERK signaling pathway-Cathepsin D-lncKRTAP5-6-3 mechanisms in photoaging cells.MethodsHaCaT cells were irradiated with 12 mJ/cm2 UVB once a day for 7 days. miR-4298 mimics and miR-4298 inhibitors were transfected into HaCaT cells by lipo3000 transfection reagent, and the HaCaT cells were divided into three groups: blank control group; UVB-damaged group; and UVB damage+miR-4298 regulation (overexpression or inhibition) group. …”
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17330
Ağ Toplumunda Dini Nefret Söylemi: Dijital Kürsü Şeyhliği
Published 2024-12-01“…X’ın etkileşim, dolaşımda kalma ve görüntüleme üzerine kurulmuş olan algoritmik yapısının dini içerikli nefret söylemlerinin slagonik bir yapıda ve manşet halde sunulmasına neden olduğu, tekfir ve reddiye geleneğinin dijital ortamlarda ötekileştirme, kalıp yargı oluşturma ve hedef gösterme olgusunu pekiştirdiği, nefret üretiminde rol oynadığı tespit edilmiştir. …”
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Cartilage structure-inspired nanofiber-hydrogel composite with robust proliferation and stable chondral lineage-specific differentiation function to orchestrate cartilage regenerat...
Published 2025-05-01“…Based on the current biomaterial system, mature and functional cartilage-ring analogs were successfully constructed and applied to repair tracheal defects. …”
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CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions
Published 2025-01-01“…Moreover, we reveal that DUB3 as a bona fide deubiquitinase of YAP1, which functionally links CK2 and YAP1 stability in a variety of human cancers. …”
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Al–Si alloyed uncoated hot stamping steels for enhanced oxidation resistance
Published 2025-03-01Get full text
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Evaluating Digital Rehabilitation Outcomes in Chronic Musculoskeletal Conditions Across Non-Obesity, Obesity, and Severe Obesity
Published 2025-01-01“…Ana P Pereira,1,* Dora Janela,1,* Anabela C Areias,1 Maria Molinos,1 Xin Tong,2 Virgílio Bento,1 Vijay Yanamadala,1,3,4 Steven P Cohen,5,6 Fernando Dias Correia,1,7 Fabíola Costa1 1Sword Health, Inc, Draper, Utah, USA; 2Department of Psychology, University of Virginia, Charlottesville, VA, USA; 3Department of Surgery, Quinnipiac University Frank H. …”
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17340
A clinical analysis and literature review of eleven cases with primary pulmonary angiosarcoma
Published 2024-12-01Get full text
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