Showing 17,301 - 17,320 results of 17,351 for search 'Xinu~', query time: 1.23s Refine Results
  1. 17301
  2. 17302
  3. 17303
  4. 17304
  5. 17305

    Network Medicine‐Based Strategy Identifies Maprotiline as a Repurposable Drug by Inhibiting PD‐L1 Expression via Targeting SPOP in Cancer by Saisai Tian, Mengting Xu, Xiangxin Geng, Jiansong Fang, Hanchen Xu, Xinying Xue, Hongmei Hu, Qing Zhang, Dianping Yu, Mengmeng Guo, Hongwei Zhang, Jinyuan Lu, Chengyang Guo, Qun Wang, Sanhong Liu, Weidong Zhang

    Published 2025-01-01
    “…Experimental validation revealed that MAP reduced PD‐L1 expression by targeting E3 ubiquitin ligase speckle‐type zinc finger structural protein (SPOP), and the combination of MAP and anti‐CTLA4 in vivo significantly enhanced the antitumor effect, providing a new alternative for the clinical treatment of colorectal and lung cancer.…”
    Get full text
    Article
  6. 17306
  7. 17307

    Anti-PD-1 exacerbates bleomycin-induced lung injury in mice via Caspase-3/GSDME-mediated pyroptosis by Fei Wang, Haiyi Deng, Maolin Zhou, Yilin Yang, Jiankui Zhou, Yansheng Wang, Xiaohong Xie, Xinqing Lin, Ming Liu, Gengyun Sun, Chengzhi Zhou

    Published 2025-01-01
    “…Consistent with the findings in the animal model, immunofluorescence and RNA sequencing of lung tissue from ICI-LI patients revealed upregulation of the expression of genes related to the GSDME-related pyroptosis pathway. …”
    Get full text
    Article
  8. 17308

    Effects of aminooxyacetic acid on learning and memory function and neurochemical changes in chronic alcoholism by Hongbo Jiang, Xunling Wang, Yingwei Liang, Yinghan Hou, Xinping Yue, Zhiyi Zhang, Dan Chen, Xinyi Fan, Ailin Du

    Published 2025-02-01
    “…Conclusion: AOAA may alleviate cognitive deficits associated with chronic alcoholism by inhibiting CBS expression, reducing H₂S levels, and enhancing 5-HT release in the prefrontal cortex. These findings suggest AOAA as a potential therapeutic strategy for alcohol-induced cognitive impairments.…”
    Get full text
    Article
  9. 17309

    Traditional pediatric massage enhanced the skeletal muscle mass in OVA-exposed adolescent rats via regulating SCFAs-FFAR2-IGF-1/AKT pathway by Lin Lin, Siyuan Li, Que Liu, Xingxing Zhang, Ying Xiong, Shaoyun Zhao, Liyue Cao, Jiaxuan Gong, Yaping Liu, Rong Wu

    Published 2025-01-01
    “…Pulmonary function (PF) was detected by whole body plethysmograph, including enhanced pause and minute ventilation. Airway allergic inflammation (AAI) status was assessed by concentrations of OVA-specific immunoglobulin E in plasma, interleukin (IL)-4 and IL-1β in bronchoalveolar lavage fluid via ELISA assay. …”
    Get full text
    Article
  10. 17310

    Subsurface drip irrigation mitigated greenhouse gas emission and improved root growth and yield in apple in semi-arid region by Jiabin Liu, Xiaodong Gao, Juanjuan Song, Mingyi Wen, Jianjun Wang, Yaohui Cai, Xining Zhao

    Published 2025-03-01
    “…In summary, SDI can enhance apple yield, foster deep root development, and reduce GHG emissions. The research findings offer empirical evidence for the sustainable growth and ecological preservation of the apple industry.…”
    Get full text
    Article
  11. 17311
  12. 17312

    Integration of Transcriptomics and Metabolomics Provides Insight into the Growth-Promoting Functions of <i>Solanum khasianum</i> Endophyte in <i>Medicago sativa</i> by Jiahui Li, Shijia Zhou, Jiaru Fang, Qihang Cai, Yanbo Yang, Zhenghai Sun, Liping Li, Weiwei Li

    Published 2025-01-01
    “…By integrating the results of transcriptome and metabolome analysis, <i>A. alstroemeriae</i> may promote plant growth by regulating genes associated with the biosynthetic pathways of flavonoids, anthocyanins, and proanthocyanidins in plants. These research findings provide a theoretical basis for future verification of the molecular response mechanisms and metabolic regulation of <i>A. alstroemeriae</i>-promoted plant growth. …”
    Get full text
    Article
  13. 17313
  14. 17314
  15. 17315

    Technicolor Middle Ages: (Ex)changes and Transformations from Medieval to Present Day Perception of Colour by Agnès Blandeau

    Published 2011-09-01
    “…Dans chacun d’eux, l’action se situe au moyen-âge. Il s’agit de The Adventures of Robin Hood (1938), Ivanhoe (1952) et The Knights of the Round Table (1953). …”
    Get full text
    Article
  16. 17316

    Folklore et écriture vernaculaire dans The Autobiography of Miss Jane Pittman by Laurence Cossu-Beaumont

    Published 2006-05-01
    “…Elle parvient à « éliminer » un adversaire des plus symboliques, le contremaître noir, en le réduisant à néant dans une réplique emblématique du pouvoir du signifyin(g) (« You ain’t nothing but Nothing » p. 11). La veille femme, sage mais non résignée, devient trickster à la fin du récit. …”
    Get full text
    Article
  17. 17317
  18. 17318

    Regulatory signatures involved in the cell cycle pathway contribute to egg production heterosis in chicken by Jingwei Yuan, Yuanmei Wang, Yanyan Sun, Yunlei Li, Aixin Ni, Qin Li, Hanhan Yang, Xinying Xu, Yunhe Zong, Hui Ma, Jilan Chen

    Published 2025-02-01
    “…Conclusion Our study characterized the dynamic profile of genome-wide gene expression in ovary and highlighted the role of dominant expression of cell cycle pathway genes in heterosis. These findings provided new insights for the molecular mechanism of egg production heterosis, which would facilitate the rational choice of suitable parents for producing crossbred chickens with higher egg production.…”
    Get full text
    Article
  19. 17319

    Comparative Analysis of Carbon Density Simulation Methods in Grassland Ecosystems: A Case Study from Gansu Province, China by Luyao Wu, Jiaqiang Du, Xinying Liu, Lijuan Li, Xiaoqian Zhu, Xiya Chen, Yue Gong, Yushuo Li

    Published 2025-01-01
    “…In contrast, the SOC estimates followed an opposite trend, with the overall approach yielding a higher <i>R</i><sup>2</sup> value of 0.92. (4) Generally, variable selection significantly enhanced model accuracy, with spatial and non-parametric models demonstrating superior precision and stability in estimating the four carbon density components of grassland. These findings provide methodological guidance for converting sample point carbon density data into regional-scale estimates of grassland carbon storage.…”
    Get full text
    Article
  20. 17320