Evaluating the impact of a multimodal perinatal education program on birth preparedness, mental health, and birth outcomes among rural primiparous women: a retrospective cohort stu... by Wei Li, TaiFang Ren, GuiHong Xu, YongShu Wang

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Effect of Electroacupuncture on Shoulder Subluxation in Poststroke Patients with Hemiplegic Shoulder Pain: A Sham-Controlled Study Using Multidimensional Musculoskeletal Ultrasound... by Minghong Sui, Naifu Jiang, Luhui Yan, Jiaqing Liu, Bin Luo, Chenxi Zhang, Tiebin Yan, Yun Xiang, Guanglin Li

“…In the SEA group, the EA was applied 15 mm away from the Lou gu (SP7), Di ji (SP8), Jiao xin (KI8), and Zhu bin (KI9) acupoints. Both groups underwent treatment 30 minutes/day, five days a week, for two weeks using dense waves with a frequency of 2/100 Hz. …”
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A pH-responsive PROTAC-based nanosystem triggers tumor-specific ferroptosis to construct in situ tumor vaccines by Linghong Huang, Xinyuan Sun, Qinhua Zuo, Ting Song, Ning Liu, Zonghua Liu, Wei Xue

Subjects: “…In situ tumor vaccines…”
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Exploring the Causal Relationship and Molecular Mechanisms Between Fasting Insulin and Androgenetic Alopecia: A Mendelian Randomization Study with Bioinformatics Analysis by Ding X, Bai Z, Wang W, Gu Y, Li Z, Fan Y

“…Xiaoxia Ding,1,* Zicheng Bai,2,* Wenwen Wang,2 Yu Gu,3 Zhiming Li,2 Yibin Fan1 1Center for Plastic & Reconstructive Surgery, Department of Dermatology, Zhejiang Provincial People’s Hospital (Affiliated People’s Hospital), Hangzhou Medical College, Hangzhou, Zhejiang, People’s Republic of China; 2Department of Dermatology and Venereology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China; 3Department of Dermatology, The First People’s Hospital of Aksu Prefecture, Aksu, XinJiang, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yibin Fan, Email fanyibin@hmc.edu.cn; Zhiming Li, Email zhi-mingli@wmu.edu.comBackground: Prior studies have suggested a significant connection between fasting insulin (FI) and androgenetic alopecia (AGA), but the exact cause of this connection and underlying molecular mechanism has not been clarified. …”
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Advancements and Challenges in Immune Protection Strategies for Islet Transplantation by Xue Wang, Ziyuan Zeng, Dayan Li, Kai Wang, Wei Zhang, Yang Yu, Xi Wang

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Construction of All Solid State Bi2MoO6/Bi2WO6@Ti3C2 MXene Heterostructure System and the Mechanism Study of the Z-scheme Photocatalysis by Dongfang Zhang, Junkun Liu, Qiang Liu, Jiaxun Wang, Yang Qu

“…After irradiation for 80 min, the as-made Bi2MoO6 /Bi2WO6@Ti3C2 MXene has the best photocatalytic performance, and the degradation rate constant was 3~4 folds higher than that of pure Bi2MoO6 or Bi2WO6. …”
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The influence of titanium alloys phase composition on the surface roughness parameters obtained in the process of wire EDM by A. A. Fedorov, Yu. E. Zhdanova, A. V. Linovsky, N. V. Bobkov, Iu. O. Bredgauer

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Solid Self-Microemulsifying Drug Delivery System for Improved Oral Bioavailability of Relugolix: Preparation and Evaluation by Li ZL, Deng GX, Fang CZ, Zhao YQ, Yuan J, Chen L, Zhong HJ, Guo F

“…Zi-Lin Li,1,* Guo-Xing Deng,1,* Chuan-Zhou Fang,1,* Yue-Qi Zhao,1 Jing Yuan,2 Liang Chen,3 Hai-Jun Zhong,1 Feng Guo1 1School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China; 2College of Basic Medicine and Forensic Medicine, Henan University of Science and Technology, Luoyang, 471000, People’s Republic of China; 3Jiangxi Prozin Pharmaceutical Co., LTD, Jian, 343100, People’s Republic of China*These authors contributed equally to this workCorrespondence: Feng Guo; Hai-JunZhong, School of Pharmacy, Jiangxi Medical College, Nanchang University, Nanchang, 330006, People’s Republic of China, Tel +86 0791 86361839, Email fengguo@ncu.edu.cn; zhonghj@ncu.edu.cnPurpose: To improve the oral absorption of relugolix (RLGL), which has low oral bioavailability due to its low solubility and being a substrate of P-glycoprotein (P-gp). …”
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Rhein Mitigates Lung Injury in Severe Acute Pancreatitis Through the Inhibition of MARK4-Mediated Microtubule Destabilization by Sun Z, Liu J, Ge P, Cao Y, Liu J, Wen H, Luo X, Pei B, Jin Z, Li H, Xun L, Luo Y, Yang Q, Chen H

“…Zhenxuan Sun,1– 3,* Jie Liu,1– 3,* Peng Ge,1– 3,* Yinan Cao,4 Jin Liu,1– 3 Haiyun Wen,1– 3 Xinyu Luo,1– 3 Boliang Pei,1– 3 Zuocang Jin,1,3 Huijuan Li,3 Lu Xun,1– 3 Yalan Luo,5 Qi Yang,6 Hailong Chen1– 3 1Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 2Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 3Laboratory of Integrative Medicine, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 4Day Surgery Center, Dalian Municipal Central Hospital, Dalian, Liaoning, 116033, People’s Republic of China; 5Department of Gastroenterology, The First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116011, People’s Republic of China; 6Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning, 116023, People’s Republic of China*These authors contributed equally to this workCorrespondence: Hailong Chen, Department of General Surgery, The First Affiliated Hospital of Dalian Medical University, Zhongshan Road 222, Dalian, Liaoning, 116011, People’s Republic of China, Tel +86 411 83635963, Fax +86 411 83622844, Email chenhailong@dmu.edu.cnPurpose: Explore the therapeutic effect and molecular mechanism of rhein on severe acute pancreatitis associated acute lung injury (SAP-ALI).Methods: The SAP-ALI rat model was constructed by retrograde injection of 5% sodium taurocholate into the pancreaticobiliary duct, and pulmonary microvascular endothelial cell (PMVEC) injury model was induced by LPS. …”
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Rigor y objetividad como fundamentos de la racionalidad de la física en Evandro Agazzi by Linda Marcela Rivera Guerrero, Arjuna Gabriel Castellanos Muñoz, Carlos Andrés Gómez Rodas

“…Así pues, el artículo no se agota en una descripción del pensamiento de Agazzi, sino que aplica sus ideas al ámbito concreto de la física, explicitando ideas que no han sido lo suficientemente explicitadas por el filósofo italiano. …”
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Exploring the Impact of Systemic Inflammatory Regulators on Rosacea Risk: A Bidirectional Mendelian Randomization Analysis by Xue Q, Pan JP, Qian D, Ji J, Fei LY, Yao S, Tan X, Fan WG

“…This study employed a two-sample bidirectional Mendelian randomization (MR) analysis to investigate the causal links between systemic inflammatory regulators and rosacea.Methods: Data on 41 cytokines and growth factors were analyzed from a genome-wide association study (GWAS) meta-analysis involving 8293 individuals and genetic data from the FinnGen database, comprising 1195 rosacea cases and 211,139 controls. …”
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Evaluation of fluorinated phospholipid analogs: A study on ADMET profiles, molecular docking and dynamics simulation in anticancer therapy by Saqib Ishaq, Obaid Habib, Abdul Aziz, Raheel Tahir, Hira Mushtaq, Said Hassan, Sarah Sarwar, Mohammad S. Mubarak, Ajaz Ahmad, Amin Ullah

“…Using evolved computational approaches, this research evaluated their ADMET (absorption, distribution, metabolism, excretion and toxicity) profiles receptor binding affinities and molecular dynamics. Molecular docking discernible vigorous interactions with Edelfosine drug displaying greater binding stability and consistent hydrogen bonding as confirmed by 100 ns molecular dynamics simulations. …”
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Evaluation of cellular and physiological alterations of cells from Mytilus galloprovincialis exposed to benzisothiazolinone by Federica Impellitteri, Kristian Riolo, Giorgia Zicarelli, Miriam Porretti, Cristiana Roberta Multisanti, Giuseppe Piccione, Alessia Giannetto, Caterina Faggio

“…It is readily detectable in pesticides, polishes, printing inks and detergents. This extensive use is reflected in a vast amount of this compound in the environment, which may cause toxic effects in organisms that come in contact with it. …”
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Structure and immunomodulatory activity of Lentinus edodes polysaccharides modified by probiotic fermentation by Jingjing Liang, Meina Zhang, Xiaohan Li, Yuan Yue, Xiaowei Wang, Mengzhen Han, Tianli Yue, Zhouli Wang, Zhenpeng Gao

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A Rare Case of Spontaneous Heterotopic Pregnancy at 12 weeks of Gestation Following Natural Conception With Literature Review by Wang F, Xu Y, Dong X, Jiang P, Yu QQ

“…Fei Wang,1,* Yuting Xu,1,* Xin Dong,2 Pei Jiang,3 Qing-Qing Yu4 1Department of Gynecology, Jining No.1 People’s Hospital, Jining, People’s Republic of China; 2Department of Ultrasonography, Jining No.1 People’s Hospital, Jining, People’s Republic of China; 3Translational Pharmaceutical Laboratory, Jining NO.1 People’s Hospital Jining, People’s Republic of China; 4Clinical Research Center, Jining NO.1 People’s Hospital, Jining, People’s Republic of China*These authors contributed equally to this workCorrespondence: Qing-Qing Yu, Clinical Research Center, Jining No.1 People’s Hospital, Jining, People’s Republic of China, 272011, Email yuqingqing_lucky@163.com Pei Jiang, Translational Pharmaceutical Laboratory, Jining No.1 People’s Hospital, Jining, 272011, People’s Republic of China, Email jiangpeicsu@sina.comBackground: Spontaneous heterotopic pregnancy is an uncommon and possibly serious problem characterized by maternities at unique implantation sites, with only one occurring in the intrauterine cavity. …”
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Development and validation of a deep learning-enhanced prediction model for the likelihood of pulmonary embolism by Yu Tian, Yu Tian, Jingjie Liu, Shan Wu, Yucong Zheng, Rongye Han, Qianhui Bao, Lei Li, Lei Li, Tao Yang

“…Based on this, we have also developed a Web server, PulmoRiskAI, for real-time clinician operation.ConclusionThe PE-Mind model improves prediction accuracy and reliability for assessing PE risk in acute DVT patients. …”
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The Effectiveness of Acupuncture on Myofascial Trigger Points Versus Traditional Chinese Medicine Acupoints for Treating Plantar Fasciitis With Low Back Pain: A Study Protocol for... by Huang Z, Liang X, Luo Y, Fang Z, Xu M, Xu Y, Cheng S, Li L

“…Ziling Huang,1 Xin Liang,1 Yuheng Luo,1 Zhou Fang,2 Ming Xu,1 Yinqin Xu,1 Shan Cheng,3 Lihong Li1 1Department of Acupuncture and Moxibustion, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of China; 2Department of Orthopedics, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of China; 3Ultrasound Center, The Affiliated Hospital of Guizhou Medical University, Guizhou, People’s Republic of ChinaCorrespondence: Lihong Li, Email 1109718711@qq.comBackground: Plantar fasciitis is a common cause of heel pain, often associated with a higher rate of low back pain. …”
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