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581
Functional Role of P-Glycoprotein and Binding Protein Effect on the Placental Transfer of Lopinavir/Ritonavir in the Ex Vivo Human Perfusion Model
Published 2009-01-01“…After the control phase of each experiment, the P-glycoprotein inhibitor ciclosporin A was added at middle perfusion (45 minutes). Fetal Transfer Rate (FTR) and Clearance Index (CLI) were compared between the 2 phases. …”
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582
Structural and free energy landscape analysis for the discovery of antiviral compounds targeting the cap-binding domain of influenza polymerase PB2
Published 2024-10-01Subjects: Get full text
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583
Investigation of Vitamin D-Binding Protein Polymorphism Impact on Coronary Artery Disease and Relationship with Longevity: Own Data and a Review
Published 2016-01-01“…The aim of the study was to assess the effect of vitamin D-binding protein (DBP) polymorphism on coronary artery disease (CAD). …”
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584
Analysis of “Dr Ding Xiang” on WeChat in China to Determine Factors Influencing Readership on Medical Social Media: Observational Study
Published 2025-01-01“…MethodsA total of 5286 articles published on the “Dr Ding Xiang” WOA from January 2021 to December 2021 were collected and analyzed. …”
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Large exciton binding energy in a bulk van der Waals magnet from quasi-1D electronic localization
Published 2025-01-01“…Bulk systems with large exciton binding energies, on the other hand, are rare and the mechanisms driving their stability are still relatively unexplored. …”
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Binding and cleavage of pro-urokinase by a tegument extract of Fasciola hepatica newly excysted juveniles activate the host fibrinolytic system
Published 2025-01-01“…We have previously shown that FhNEJ are capable of binding plasminogen (PLG), the zymogen of plasmin, on their tegument surface, which leads to plasmin generation in the presence of host-derived PLG activators and subsequent degradation of laminin, a major component of the intestinal ECM. …”
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590
Associations of sleep quality and fall risk among older adult outpatients at Thai Binh Medical University Hospital, Northern Vietnam
Published 2025-01-01“…This study aimed to determine the correlation between sleep quality and fall risk among the elderly, providing knowledge for fall prevention in this population in Vietnam.MethodsA cross-sectional study was conducted on 404 elderly patients who visited and were treated as outpatients at Thai Binh University Hospital from October 2023 to June 2024. …”
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Retour sur la révolte du bassin minier. Les cinq leçons politiques d’un conflit social inédit
Published 2021-02-01Get full text
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“One Ring to Bind Them All”—Part II: Identification of Promising G-Quadruplex Ligands by Screening of Cyclophane-Type Macrocycles
Published 2010-01-01“…The four selected hits possess sophisticated architectures, more particularly the presence of a pendant side-arm as well as the existence of a particular topological arrangement appear to be strong determinants of quadruplex binding. These compounds are thus likely to create multiple contacts with the target that may be at the origin of their high selectivity, thereby suggesting that this class of macrocycles offers unique advantages for targeting G-quadruplex-DNA.…”
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593
Synthesis, Characterization, and DNA-Binding Kinetics of New Pd(II) and Pt(II) Thiosemicarbazone Complexes: Spectral, Structural, and Anticancer Evaluation
Published 2020-01-01“…The compounds had low to moderate anticancer potency with their spectral and structural properties correlating with the corresponding anticancer activity profiles. DNA binding modes were studied by spectroscopy and were comparable to known DNA intercalators. …”
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Сandidate SNP-markers of rheumatoid arthritis that can significantly alter the affinity of the TATA-binding protein for human gene promoters
Published 2020-01-01Subjects: “…tata binding protein (tbp)…”
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Targeted Delivery of Nanovaccine to Dendritic Cells via DC-Binding Peptides Induces Potent Antiviral Immunity in vivo [Expression of Concern]
Published 2025-01-01“…Lu Y, Liu ZH, Li YX, Xu HL, Fang WH, He F. Int J Nanomedicine. 2022;17:1593—1608. …”
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Fixation and reversion of mutations in the receptor-binding domain of the SARS-CoV-2 spike protein: A 2020–2024 analysis
Published 2024-12-01Subjects: Get full text
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