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541
The bacterial response regulator ArcA uses a diverse binding site architecture to regulate carbon oxidation globally.
Published 2013-01-01“…Unexpectedly, bioinformatic analysis of the sequences bound by ArcA in ChIP-seq revealed that most ArcA binding sites contain additional direct repeat elements beyond the two required for binding an ArcA dimer. …”
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542
COMPUTATIONAL ANALYSIS AND FUNCTIONAL ANNOTATION OF AP2/ERF TRANSCRIPTION FACTOR BINDING SITES IN ARABIDOPSIS THALIANA L. GENOME
Published 2015-01-01Subjects: Get full text
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543
Near-Infrared Optical Imaging of Ovarian Cancer Xenografts with Novel α3-Integrin Binding Peptide “OA02”
Published 2005-10-01“…Through screening of random one-bead one-compound (OBOC) libraries, we previously identified cyclic peptides with the cDGXGXXc motif that bind to α3 integrin subunit on ovarian adenocarcinoma cell lines ES-2, SKOV-3, and CaOV-3. …”
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Computational identification of anti-cancer compounds targeting the RNA-binding domain of human FOX-1 protein (RBFOX1)
Published 2025-01-01“…Consequently, our findings provide a potential framework for researchers to further explore in vivo and in vitro analyses of inhibitors targeting the HBFOX1 gene, representing a potential advancement in cancer treatment.…”
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546
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Structural insights into HIV-2 CA lattice formation and FG-pocket binding revealed by single-particle cryo-EM
Published 2025-02-01“…While the overall fold and mode of FG-peptide binding is conserved with HIV-1, this study reveals distinctive features of the HIV-2 CA lattice, including differing structural character at regions of host factor interactions and divergence in the mechanism of formation of CA hexamers and pentamers. …”
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548
A KSHV RNA-binding protein promotes FOS to inhibit nuclease AEN and transactivate RGS2 for AKT phosphorylation
Published 2025-01-01Subjects: Get full text
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549
Urinary Intestinal Fatty Acid-Binding Protein Can Distinguish Necrotizing Enterocolitis from Sepsis in Early Stage of the Disease
Published 2016-01-01“…Here, we analyzed if markers of gut mucosa damage, caspase cleaved cytokeratin 18 (ccCK18) and intestinal fatty acid-binding protein (I-FABP), could be used for differential diagnostics of NEC at early stage of disease. …”
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550
A single mutation in dairy cow-associated H5N1 viruses increases receptor binding breadth
Published 2024-12-01“…We find that H5 from A/Texas/37/2024, an isolate from the dairy cow outbreak, has increased binding breadth to core glycans bearing terminal α2,3 sialic acids, the avian receptor, compared to historical and recent 2.3.4.4b H5N1 viruses. …”
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551
Psychosis in a 15-Year-Old Female with Herpes Simplex Encephalitis in a Background of Mannose-Binding Lecithin Deficiency
Published 2017-01-01“…Of note in this case report is psychotic disorder that occurred following reactivation of herpes simplex infection in a background of mannose-binding lecithin (MBL) deficiency, childhood EBV infection, and severe psychosocial stress. …”
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552
Investigation into IgG/IgE binding capacity and gut microbiota of digestion products derived from glycated ovalbumin
Published 2024-11-01Subjects: Get full text
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553
Disruption of the β-catenin destruction complex via Ephexin1-Axin1 interaction promotes colorectal cancer proliferation
Published 2025-01-01“…Importantly, our findings also suggest that targeting Ephexin1 may increase the efficacy of Wnt/β-catenin pathway inhibitors in CRC treatment. …”
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554
Identification of potential corticosteroid binding sites on the SARS CoV-2 main protease Mpro — in silico docking study
Published 2024-08-01“…Molecular docking methods (AutoDock Tools 1.5.7, AutoDock Vina 1.1.2) were used to gain insight into the binding affinity Mpro with systemic corticosteroids such as dexamethasone (DEX), prednisone (PRED), prednisolone (PNL), methylprednisolone (Medrol), triamcinolone (TAC), and hydrocortisone (HCT). …”
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555
Serum fatty acid-binding protein 3 levels differentiate active from inactive myositis and correlate with response to therapy
Published 2020-01-01“…Background: Delay in the diagnosis of idiopathic inflammatory myopathies (IIMs) and resultant muscle wasting leads to a setting, wherein conventional biomarkers fail to identify inflammation amid damage. Fatty acid-binding protein 3 (FABP3) has a selective location and function lending unique potential as a specific biomarker in IIM. …”
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556
The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells
Published 2018-01-01“…RNA-binding proteins (RBPs) mediate the localization, stability, and translation of the target transcripts and fine-tune the physiological functions of the proteins encoded. …”
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557
Santificado a una judía comunista: la recomodación de la identidad brasileña en Olga (Monjardin, Brasil, 2004)
Published 2006-01-01Subjects: Get full text
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558
Forges en la gran pantalla: País, S.A. (1975) y El Bengador Gusticiero y su pastelera madre (1977)
Published 2025-01-01Subjects: Get full text
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