Increasing brain half-life of antibodies by additional binding to myelin oligodendrocyte glycoprotein, a CNS specific protein by Marie-Lynn Cuypers, Tom Jaspers, Jarne Clerckx, Simon Leekens, Christopher Cawthorne, Guy Bormans, Frederik Cleeren, Nick Geukens, Bart De Strooper, Maarten Dewilde

“…Methods Alpaca immunization with mouse/human MOG, and subsequent phage selections and screenings for MOG binding single variable domain antibodies (VHHs) were performed to find mouse/human cross-reactive VHHs. …”
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Key predistribution with location and time binding:novel approach against node replication attacks in wireless sensor networks by FU Fei, QI Wang-dong

“…Since replicas were deployed at different locations other than the original,they could not be accepted by their neighbors. …”
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Pseudomonas aeruginosa pili and flagella mediate distinct binding and signaling events at the apical and basolateral surface of airway epithelium. by Iwona Bucior, Julia F Pielage, Joanne N Engel

“…In contrast, flagella-coated beads bind to or aggregate preferentially with HS or HSPGs, but demonstrate little binding to N-glycans. …”
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Structural and functional analysis reveals the catalytic mechanism and substrate binding mode of the broad-spectrum endolysin Ply2741 by Shuang Wang, Xinxin Li, Jiahui Ma, Xiaochao Duan, Haiyan Wang, Linkang Wang, Dayue Hu, Wenwu Jiang, Xiangmin Li, Ping Qian

“…Furthermore, the key residues (R189 and W250) in the Ply2741 cell wall binding domain (CBD) responsible for binding to peptidoglycan were revealed by molecular docking and fluorescence-activated cell sorting (FACS) analysis. …”
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RNA-Binding Proteins and Alternative Splicing Genes Are Coregulated in Human Retinal Endothelial Cells Treated with High Glucose by Hongran Zhao, Hui Kong, Bozhao Wang, Sihui Wu, Tianran Chen, Yan Cui

“…To explore the relevant RNA-binding proteins (RBPs) and alternative splicing events (ASEs) in diabetic retinopathy (DR). …”
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Role of lipid binding protein, Niemann pick type C-2, in enhancing shrimp sperm physiological function by Thitiporn Khongkha, Alyssa Rattanadechakul, Piyaporn Surinlert, Orawan Thongsum, Supawich Boonkua, Kessiri Kongmanas, Monsicha Somrit, Wattana Weerachatyanukul, Somluk Asuvapongpatana

“…In shrimp, we have previously shown that the level of cholesterol (CHO) is significantly reduced in vas deferens sperm when compared with sperm in the testes, presumably due to the sequestering action of the lipid-binding protein, one of which is Niemann-Pick Type C-2 (NPC2). …”
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ENRICHING CLASSROOMS WITH TECHNOLOGY: EFFECTIVENESS OF ICT INTEGRATION IN TEACHING AGRICULTURAL SCIENCE IN SENIOR SECONDARY SCHOOLS IN BENUE STATE by GBEYONGU FREDERICK TERKIMBI, AKAA CHARITY WANGER, ONU DEBORAH OGBENE

“…This paper stressed on the integration of ICT tools in teaching Agricultural Science in Senior Secondary Schools in Benue State. The paper dealt with the impact of ICT tools in teaching Agricultural Science. …”
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High-affinity promotor binding of YhaJ mediates a low signal leakage for effective DNT detection by Myeongbin Kim, Ryun Kang, Hye Min Park, Eun Bi Cho, Hye Rim Lee, Seong Eon Ryu

“…By the structure determination of the DNA-binding domain (DBD) of YhaJ and the structure-guided mutagenesis, we found that the mutation increasing the DNA binding affinity decreases the signal leakage in the absence of an effector, resulting in a significant enhancement of the response ratio for the DNT metabolite detection. …”
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Accès psychotique aigu révélant un neurolupus : à propos d’un patient de 21 ans by JE Savadogo, I Compaoré, WJS Zabsonré/Tiendrébéogo, B Bagué, DD Ouédraogo

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Complexed Crystal Structure of Saccharomyces cerevisiae Dihydroorotase with Inhibitor 5-Fluoroorotate Reveals a New Binding Mode by Hong-Hsiang Guan, Yen-Hua Huang, En-Shyh Lin, Chun-Jung Chen, Cheng-Yang Huang

“…Based on these lines of molecular evidence, we discussed whether these different binding modes are species- or crystallography-dependent.…”
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GATA4 binding to the Sox9 enhancer mXYSRa/Enh13 is critical for testis differentiation in mouse by Yuya Ogawa, Iku Tsuchiya, Shogo Yanai, Takashi Baba, Ken-Ichirou Morohashi, Takehiko Sasaki, Junko Sasaki, Miho Terao, Atsumi Tsuji-Hosokawa, Shuji Takada

“…Two nucleotide substitutions within the sequence were sufficient for male-to-female sex reversal. In vivo binding assay by CUT&RUN revealed that GATA4 binds to the sequence. …”
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Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety by Enrique Pérez-Garci, Kateryna Pysanenko, Giorgio Rizzi, Florian Studer, Daniel Ulrich, Thorsten Fritzius, Simon Früh, Alessandra Porcu, Valérie Besseyrias, Adolf Melichar, Martin Gassmann, Tania Rinaldi Barkat, Rostislav Tureček, Kelly R. Tan, Bernhard Bettler

“…KCTD16−/− mice exhibit increased anxiety-like behavior in response to stress - a behavior replicated by CRISPR/Cas9-mediated KCTD16 ablation in DAVTA neurons or by intra-VTA infusion of an HCN antagonist in wild-type mice. Our findings support that the retention of HCN channels at GABAergic synapses by GBRs in DAVTA neurons provides a negative feedback mechanism that restricts IPSP duration and mitigates the development of anxiety.…”
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Computational analysis of the effect of a binding protein (RbpA) on the dynamics of Mycobacterium tuberculosis RNA polymerase assembly. by Sneha Bheemireddy, Ramanathan Sowdhamini, Narayanaswamy Srinivasan

“…<h4>Background</h4>RNA polymerase-binding protein A (RbpA) is an actinomycetes-specific protein crucial for the growth and survival of the pathogen Mycobacterium tuberculosis. …”
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The Role of Sialic Acid-Binding Receptors (Siglecs) in the Immunomodulatory Effects of Trypanosoma cruzi Sialoglycoproteins on the Protective Immunity of the Host by Alexandre Morrot

“…In what follows we propose that signaling via sialic acid-binding Ig-like lectin receptors for these highly sialylated structures on host cells contributes to the arrest of cell cycle progression in the G1 phase and may allow the parasite to modulate the immune system of the host.…”
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Novel FeII and CoII Complexes of Natural Product Tryptanthrin: Synthesis and Binding with G-Quadruplex DNA by Yi-ning Zhong, Yan Zhang, Yun-qiong Gu, Shi-yun Wu, Wen-ying Shen, Ming-xiong Tan

“…Single-crystal X-ray diffraction analyses show that these complexes display distorted four-coordinated tetrahedron geometry via two heterocyclic nitrogen and oxygen atoms from tryptanthrin ligand. Binding with G-quadruplex DNA properties revealed that both complexes were found to exhibit significant interaction with G-quadruplex DNA. …”
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Roland CANU, Johann CHAULET, Caroline DATCHARY et Julien FIGEAC (dir.) (2018), Critiques du numérique by Françoise Paquienséguy

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Nicolaus Copernicus Üniversitesi Kütüphanesi (Biblioteka Glowna) : Bina ve Derme Özellikleri ile İlgili Bir İnceleme by Fatih Rukancı, Hakan Anameriç

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Synthesis, Characterization, Biological Activity and DNA Binding Studies of Metal Complexes with 4-Aminoantipyrine Schiff Base Ligand by B. Anupama, M. Padmaja, C. Gyana Kumari

“…Biological screening of the complexes reveals that the Schiff base transition metal complexes show significant activity against microorganisms. Binding of Co(II) complex with calf thymus DNA (CT DNA) was studied by spectral methods.…”
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Identification of plasma proteins binding oxidized phospholipids using pull-down proteomics and OxLDL masking assay‡ by Philipp Jokesch, Lisa Holzer, Lydia Jantscher, Sebastian Guttzeit, Rudolf Übelhart, Olga Oskolkova, Valery Bochkov, Bernd Gesslbauer

“…The latter group of proteins is essentially not investigated because only three OxPC-binding plasma proteins are currently known. The goal of this work was to characterize a broad spectrum of plasma proteins selectively binding OxPLs. …”
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Solving Constrained Flow-Shop Scheduling Problem through Multistage Fuzzy Binding Approach with Fuzzy Due Dates by Hamiden Abd El-Wahed Khalifa, Sultan S. Alodhaibi, Pavan Kumar

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