Abundant repressor binding sites in human enhancers are associated with the fine-tuning of gene regulation by Wei Song, Ivan Ovcharenko

“…Our work reveals modulated enhancer activity and adaptable gene regulation through the evolutionary dynamics of TF binding sites.…”
Get full text

Spatiotemporal analysis of Plasmodium falciparum erythrocyte binding antigen-175 gene dimorphism in Ghana by Abraham Y. Kpirikai, Belinda A. Ofosu, Josie N. A. Okai, Victor Kornu, Abdul Rashid Kassim, Esther Donkor, Frederica Malm, Osumanu Ahmed, Mona-Liza E. Sakyi, Samirah Saiid, Albert Yao Kudakpo, Charles Mensah, Francis Dzabeng, Collins Morang’a, Gordon A. Awandare, Yaw Aniweh, Lucas N. Amenga-Etego

“…The merozoites stage of the parasite, crucial for asexual development invade erythrocytes through ligand-receptor interactions. Erythrocyte binding antigen (EBA)-175 is one of the key ligands facilitating invasion via interaction with glycoprotein A (GpA) receptors on the erythrocytes. …”
Get full text

Deciphering olfactory receptor binding mechanisms: a structural and dynamic perspective on olfactory receptors by Jingtao Wang, Jingtao Wang, Qidong Zhang, Wu Fan, Qingzhao Shi, Jian Mao, Jianping Xie, Guobi Chai, Guobi Chai, Chenglei Zhang

“…This has provided new insights into the binding mechanisms between odor molecules and olfactory receptors. …”
Get full text

“Ain’t the American Dream Grand”: Satirical Play in Rockstar’s Grand Theft Auto V by John Wills

Get full text

Gérard Noiriel, Le massacre des Italiens, Aigues-Mortes, 17 août 1893 by Jean-Lucien Sanchez

Get full text

Actin-Binding Proteins as Potential Biomarkers for Chronic Inflammation-Induced Cancer Diagnosis and Therapy by Yu-Gui Zhang, Jiang-Tao Niu, Hong-Wei Wu, Xin-Lei Si, Shu-Juan Zhang, Dong-Hui Li, Tian-Tian Bian, Yue-Feng Li, Xing-Ke Yan

“…Actin-binding proteins (ABPs), by interacting with actin, regulate the polymerization, depolymerization, bundling, and cross-linking of actin filaments, directly or indirectly, thereby mediating the maintenance of cell morphology, cell movement, and many other biological functions. …”
Get full text

A multivalent binding model infers antibody Fc species from systems serology. by Armaan A Abraham, Zhixin Cyrillus Tan, Priyanka Shrestha, Emily R Bozich, Aaron S Meyer

“…Systems serology aims to broadly profile the antigen binding, Fc biophysical features, immune receptor engagement, and effector functions of antibodies. …”
Get full text

S-DCNN: prediction of ATP binding residues by deep convolutional neural network based on SMOTE by Sixi Hao, Sixi Hao, Cai-Yan Li, Xiuzhen Hu, Zhenxing Feng, Gaimei Zhang, Caiyun Yang, Huimin Hu

Subjects: “…ATP binding residues…”
Get full text

A Promising Candidate: Heparin-Binding Protein Steps onto the Stage of Sepsis Prediction by Yang Yang, Guihuan Liu, Qingnan He, Jie Shen, Linyong Xu, Ping Zhu, Mingyi Zhao

“…Heparin-binding protein (HBP) is a granular protein derived from polynuclear neutrophils. …”
Get full text

Binge Eating Behavior and Weight Loss Maintenance over a 2-Year Period by Carly R. Pacanowski, Meghan M. Senso, Kristin Oriogun, A. Lauren Crain, Nancy E. Sherwood

Get full text

Quercetin alleviates endothelial dysfunction in preeclampsia by inhibiting ferroptosis and inflammation through EGFR binding by Meiting Shi, Lu Sun, Jiachun Wei, Yao Shen, Jian Wang, Ping Zhang, Xiaofeng Yang, Yuzhen Ding, Wanchang Yin, Xinyao Lu, Xuesong Yang, Guang Wang, Ruiman Li

“…Furthermore, QCT alleviates PE-like maternal manifestations and endothelial dysfunction in the placenta of the selective reduced uteroplacental perfusion (sRUPP) rat model through binding to the epidermal growth factor receptor (EGFR). …”
Get full text

Evolution of sequence, structural and functional diversity of the ubiquitous DNA/RNA-binding Alba domain by Jaiganesh Jagadeesh, Shruthi Sridhar Vembar

“…Abstract The DNA/RNA-binding Alba domain is prevalent across all kingdoms of life. …”
Get full text

Residual Capability of Alkali Binding by Hydrated Pozzolanic Cements in Long-Service Concrete Structures by Mario Berra, Teresa Mangialardi, Antonio Evangelista Paolini

“…An experimental procedure was developed and applied to cement pastes made with two different pozzolanic cements (CEM IV/B (P) and CEM IV/B (V)) in order to ascertain the existence of a residual capability of alkali binding by long-term hydrated pozzolanic cements and, at the same time, to evaluate the alkali retention capability and the concentration of OH− ions in the pore solution of such cementitious matrices. …”
Get full text

A Review of Electronic Band Structure of Graphene and Carbon Nanotubes Using Tight Binding by Davood Fathi

“…The electronic band structure variations of single-walled carbon nanotubes (SWCNTs) using Huckle/tight binding approximation theory are studied. According to the chirality indices, the related expressions for energy dispersion variations of these elements are derived and plotted for zigzag and chiral nanotubes.…”
Get full text

EFFECT OF BASIC AMENITIES ON SOCIO-ECONOMIC DEVELOPMENT OF RURAL AREAS IN BENUE STATE NIGERIA by ONYOWO REBECCA ATUNGWU

“…The data collected were analysed using inferential statistics (regression analysis). Findings of the study indicated that primary healthcare, pipe-borne water, education, and rural electrification have significant effect on socioeconomic development of rural areas in Benue State, Nigeria. …”
Get full text

CIRBP Regulates Pancreatic Cancer Cell Ferroptosis and Growth by Directly Binding to p53 by Hongqiang Gao, Ran Xie, Rong Huang, Chonglin Wang, Yue Wang, Dongdong Wang, Kaimin Liu, Conghui Yang, Qingxiong Yang, Long Chen

“…Pancreatic cancer is one of the most malignant gastrointestinal tumors, and it is of great significance to explore the molecular mechanism of its progression and find new biological therapeutic targets. CIRBP is a cold-induced protein that plays a key role in many physiological and pathological processes, but its role in pancreatic cancer is still unclear. …”
Get full text

Breaking the cycle: a pilot study on autonomous Digital CBTe for recurrent binge eating by Rebecca Murphy, Charandeep Khera, Emma L. Osborne

Subjects: Get full text

Protein-ligand binding affinity prediction using multi-instance learning with docking structures by Hyojin Kim, Heesung Shim, Aditya Ranganath, Stewart He, Garrett Stevenson, Jonathan E. Allen

“…IntroductionRecent advances in 3D structure-based deep learning approaches demonstrate improved accuracy in predicting protein-ligand binding affinity in drug discovery. These methods complement physics-based computational modeling such as molecular docking for virtual high-throughput screening. …”
Get full text

Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)]4 by Bruno Pagano, Iolanda Fotticchia, Stefano De Tito, Carlo A. Mattia, Luciano Mayol, Ettore Novellino, Antonio Randazzo, Concetta Giancola

“…Distamycin A is known to bind to AT-rich sequences of duplex DNA, but it has recently been shown to interact also with G-quadruplexes. …”
Get full text

Drug-target binding affinity prediction based on power graph and word2vec by Jing Hu, Shuo Hu, Minghao Xia, Kangxing Zheng, Xiaolong Zhang

“…Results Compared with other methods, regression-based drug target affinity is more representative of the binding ability. Accurate prediction of drug target affinity can effectively reduce the time and cost of drug retargeting and new drug development. …”
Get full text