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    Health Through Discovery / by Dintiman, George B.

    Published 1989
    Subjects:
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    Book
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    Lung and blood early biomarkers for host-directed tuberculosis therapies: Secondary outcome measures from a randomized controlled trial. by Robert S Wallis, Sibuse Ginindza, Trevor Beattie, Nishanee Arjun, Morongwe Likoti, Modulakgotla Sebe, Vinodh A Edward, Mohammed Rassool, Khatija Ahmed, Katherine Fielding, Bintou A Ahidjo, Mboyo D T Vangu, Gavin Churchyard

    Published 2022-01-01
    “…Biomarkers can accelerate tuberculosis regimen development, but no studies have yet examined early biomarkers of TB-HDTs.<h4>Methods</h4>Biomarkers of inflammation and microbicidal activity were evaluated as a part of a recent phase-2 randomized controlled trial of four HDTs in 200 patients with pulmonary tuberculosis and baseline predictors of poor outcome, including CC-11050 (PDE4i), everolimus (mTORi), auranofin (oral gold salt), and ergocalciferol (vitamin D). …”
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    Relationship between pharmacotherapy for major depressive disorder and healthcare utilisation in British Columbia, Canada: a retrospective population-based cohort by Sonya Cressman, Louisa Edwards, Kimberlyn McGrail, Stirling Bryan, Alison Hoens, Rohit Vijh, Sandra Peterson, Zeina Waheed, Mary Bunka, Nick Pang, Shahzad Ghanbarian, Gavin Wong, Linda Riches, Jehannine Austin

    Published 2024-12-01
    “…The odds ratio (OR) for health service utilisation between the pharmacotherapy group and the non-pharmacotherapy group for individuals who were recently incident was 8.14 (95% CI 7.40, 8.95) for outpatient physician visits, 1.04 (95% CI 1.02, 1.07) for ED visits and 1.05 (95% CI 1.00, 1.10) for hospitalisations, after adjusting for comorbidities and other sociodemographic variables in our regression analyses, whereas for the actively prevalent group the ORs were 7.57 (7.27, 8.49), 0.91 (0.89, 0.92) and 1.00 (0.98, 1.02), respectively.Conclusion This study examined the association of pharmacotherapy on healthcare utilisation for adults with MDD in BC. …”
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    Cytokine Profile in Early Infection by Leptospira interrogans in A/J Mice by Lorena Bavia, Íris A. de Castro, Mariane Tami Amano, Ana Maria Gonçalves da Silva, Silvio Arruda Vasconcellos, Lourdes Isaac

    Published 2019-01-01
    “…The innate immune response against Leptospira is mainly dependent on phagocytosis and activation of the Complement System. …”
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