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In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies
Published 2024-12-01“…Even if the source of a given biologic is ‘fully human’, T cell epitopes that are contained in the sequences of the biologic may activate the immune system, enabling the development of anti-drug antibodies that can reduce drug efficacy and may contribute to adverse events. …”
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122
The assessment of change in human heat stress risk in Brazil projected by the CMIP6 models
Published 2025-01-01“…Climate change in Brazil is expected to increase the occurrences of heat related conditions hazardous to human health. Thresholds in the environmental conditions leading to heat stress in humans are projected to be exceeded for long periods of the year across large parts of the country. …”
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123
A Multi-Systems Approach to Human Movement after ACL Reconstruction: The Cardiopulmonary System
Published 2021-12-01“…The cardiopulmonary system plays a pivotal role in athletic and rehabilitative activities following anterior cruciate ligament reconstruction, along with serving as an important support for the functioning of other physiologic systems including the integumentary, musculoskeletal, and nervous systems. …”
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124
Both Maturation and Survival of Human Dendritic Cells are Impaired in the Presence of Anergic/Suppressor T Cells
Published 2003-01-01“…In the present work we studied the effects of co-culturing human anergic CD4+ T cells with autologous dendritic cells (DC) at different stages of maturation. …”
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125
Presenting the model of recruitment and selection of human resources of the public sector with the approach of the entrepreneurial government
Published 2024-05-01“…The results of the research show that organizational leadership style has no significant effect on human resource management and has been rejected; however, the significant effect of organizational leadership style on the competitive work environment, the competitive work environment on human resource management, and the organizational leadership style on human resource management with the mediating role of the competitive work environment has been confirmed. …”
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126
Economic, social and cultural human rights in the context of preventing the spread of COVID-19 in Ukraine
Published 2020-06-01“…Theoretical provisions and legal principles of introducing and realizing guarantees and restrictions of economic, social and cultural human rights (rights to health care, safe working conditions, business activity, equal access to public service, education, sufficient standard of living, social protection, etc.) have been analyzed. in terms of preventing the spread of COVID-19 in Ukraine. …”
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127
Active Ageing Level of Older Persons: Regional Comparison in Thailand
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128
An electrolyte-gated transistor for the monitoring of a CRISPR/Cas activity
Published 2025-05-01“…In these devices, fabricated on flexible plastic substrates, the active material (reduced graphene oxide, rGO) is deposited by printing and then functionalized with Au nanoparticles decorated with polyU RNA reporter strands. …”
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129
Socio-Economic Dimension of Human Potential of World Countries in the Digital Space of the Labor Market
Published 2023-11-01“…The authors also provide the sectoral structure of employment in Ukraine and the average annual rate of growth of the indicator level in the leading countries with a digital direction of labor market development, as well as comparative socio-economic measurement and forecasting of Germany's effective use of human potential, subject to the expansion of labor inflows and the improvement of the working capacity of active human resources. …”
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130
Scientific support for the use of psychiatric knowledge in the investigation of crimes against human life and health
Published 2023-12-01“…It has been determined that the current state of scientific significance of the use of special psychiatric and psychological knowledge in the investigation of crimes against human life and health is influenced by the peculiarities of development of criminal procedure legislation. …”
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131
Prediction of Future Terrorist Activities Using Deep Neural Networks
Published 2020-01-01“…The more the civilizations have advanced, the more the people are working towards exploring different mechanisms to protect the mankind from terrorism. …”
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132
Strengthening public health education and humanitarian response through academic volunteerism
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133
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Theoretical and methodological approaches to the problem of student’s health in the algorithm of recreational activities
Published 2022-06-01“…There are other components of health: occupational factor, genetic component, environment. One of the main activities of higher educational institutions is to educate students in high demands on themselves, the vital need to work, the desire and ability to work creatively, to replenish and improve their knowledge; lead a healthy lifestyle.…”
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135
Activities of Detective Units in the National Police of Ukraine: Current Status and Perspectives
Published 2021-07-01“…It should be noted that detective work in Ukraine is a new type of professional activity. …”
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136
Sensor selection scheme in activity recognition based on hierarchical feature reduction
Published 2018-08-01“…To better understand the activity state of human, we might need multiple sensors on different parts of the body. …”
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137
In Vitro Activity of Geldanamycin Derivatives against Schistosoma japonicum and Brugia malayi
Published 2010-01-01“…GA derivatives are being evaluated as anti-neoplastic agents, but their utility against parasites whose heat shock proteins (Hsps) have homology with human Hsp90 is unknown. The activities of four synthetic GA derivatives were tested in vitro using adult Brugia malayi and Schistosoma japonicum. …”
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138
Functionalization of selenium nanoparticles with olive polyphenols – impact on toxicity and antioxidative activity
Published 2023-12-01“…SeNPs showed lower toxicity on human hepatocellular carcinoma (HepG2) and human colorectal adenocarcinoma (Caco2) cells compared to selenite. …”
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139
What does the fox select? Spatial ecology of Rocky Mountain red fox during peaks and troughs of human recreation
Published 2025-01-01“…These findings might indicate some foxes are concentrating on the temporal and spatial resource pulse of anthropogenic food, while others exhibited more natural tactics. Our work advanced the spatial ecology of Rocky Mountain red fox, identified variation in space use tactics associated with humans and natural resources among red foxes in a heavily recreated area, and demonstrated how human activity can influence the spatial behavior of a carnivore within a national park.…”
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Lessons learnt from horse-related human fatalities: Accident analysis using HFACS-Equestrianism
Published 2025-02-01“…Also, the role of non-technical skills such as communication, effective supervision, and adequate leadership were highlighted as factors that could contribute to enhanced safety in this high-risk domain. The human-horse dyad in equestrianism is complex and unique when compared to other high-risk work and non-work activities. …”
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