Real-world outdoor air exposure effects in a model of the human airway epithelium – A comparison of healthy and asthmatic individuals using a mobile laboratory setting by Pavel Rossner, Helena Libalova, Tereza Cervena, Michal Sima, Zuzana Simova, Kristyna Vrbova, Antonin Ambroz, Zuzana Novakova, Fatima Elzeinova, Anezka Vimrova, Lubos Dittrich, Michal Vojtisek, Martin Pechout, Michal Vojtisek-Lom

Subjects: Get full text

Real-world clinical evidence of oral semaglutide on metabolic abnormalities in subjects with type 2 diabetes: a multicenter retrospective observational study (the Sapporo-Oral SEMA study) by Sho Furusawa, Hiroshi Nomoto, Chiho Oba-Yamamoto, Jun Takeuchi, Miki Ito, Hiroyoshi Kurihara, Shin Aoki, Aika Miya, Hiraku Kameda, Akinobu Nakamura, Tatsuya Atsumi

“…Oral semaglutide in subjects with type 2 diabetes improved glycemic control and body weight in a real-world clinical setting.…”
Get full text

The best young scientist award abstracts presented at the 32nd World Congress on Controversies in Obstetrics, Gynecology & Infertility (COGI), November 21–23, 2024, Lisbon, Portugal by Ahmed Ghoubara

Get full text

Renoprotective Effect of Thai Patients with Type 2 Diabetes Mellitus Treated with SGLT-2 Inhibitors versus DPP-4 Inhibitors: A Real-World Observational Study by Apichaya Chanawong, Suriyon Uitrakul, Supatcha Incomenoy, Natnicha Poonchuay

Get full text

Two-Stage Arthrodesis after an Infected Total Knee Replacement Using a Coupled Nail and Dual-Plate Construct: A Third-World Solution and Review of Options by Marlon M. Mencia, Raakesh Goalan, Atiba Akii Bua

Get full text

High tumor mutational burden predicts favorable response to anti-PD-(L)1 therapy in patients with solid tumor: a real-world pan-tumor analysis by Sehhoon Park, Jaeyun Jung, You Jeong Heo

“…TruSight Oncology 500 (TSO500) is currently used globally as a routine assay for TMB.Methods Between 2019 and 2021, 1744 patients with cancer received TSO500 assay as part of a real-world clinical practice at the Samsung Medical Center, and 426 received anti-PD-(L)1 treatment. …”
Get full text

End of the world brane dynamics in holographic 4d N $$ \mathcal{N} $$ = 4 SU(N) with 3d N $$ \mathcal{N} $$ = 2 boundary conditions by Jesús Huertas, Angel M. Uranga

“…They describe solutions with an asymptotic AdS5 × S 5 terminating at AdS4 End of the World boundary configurations, whose rich dynamics reproduces the above physical properties. …”
Get full text

The Real-World Clinical Outcomes of Heavily Pretreated HER2+ and HER2-Low Metastatic Breast Cancer Patients Treated with Trastuzumab Deruxtecan at a Single Centre by Anna-Maria Lazaratos, Matthew Dankner, Aalya Hamouda, Soumaya Labidi, Victor Cohen, Lawrence Panasci, Jennifer E. Friedmann, François Patenaude, Cristiano Ferrario, Mark Basik, April A. N. Rose, Parvaneh Fallah

Get full text

Differences in the Cardiovascular Risk Assessment in Cardiology Outpatients in Mali: Comparison between Framingham Body Mass Index-Based Tool and Low-Information World Health Organization Chart by Bâ Hamidou Oumar, Sangaré Ibrahima, Camara Youssouf, Sidibé Noumou, Coulibaly Souleymane, Cissoko Yacouba, Sidibé Samba, Konaté Massama, Maiga Asmaou Kéita, Doumbia Coumba Thiam, Touré Mamadou, Diakité Mamadou, Menta Ichaka, Diall Ilo Bella

Get full text

Durvalumab as consolidation therapy in patients who received chemoradiotherapy for unresectable stage III NSCLC: Real-world data from an expanded access program in Brazil (LACOG 0120) by Mauro Zukin, Victor Gondim, Andrea Kazumi Shimada, Ellias Magalhães e Abreu Lima, Clarissa Mathias, Williams Fernandes Barra, William Nassib William Junior, Mônica Padoan, Yuri Bittencourt, Rosely Yamamura, Carlos Eduardo Baston Silva, Letícia de Jesus Rossato, Caio de Almeida Monteiro, Rafaela Gomes de Jesus, Gustavo Gössling, Ana Caroline Zimmer Gelatti

Subjects: Get full text

10 External validation of a digital pathology-based multimodal artificial intelligence prostatebiopsy biomarker in a prospective, real-world prostate cancer cohort treated with radicalprostatectomy by A.S. Bjartell, A. Krzyzanowska, V. Liu, M. Thierney, T. Joyce, M. Sjöström, M.M. Palominos-Rivera, E. Chen, A. Kraft, F. Esteva A.E, Feng

Get full text

Correction: Filling the data gap on CGRP mAb therapy in low- to middle-income countries in Southeast Asia: insights from a real-world study in Thailand by Prakit Anukoolwittaya, Akarin Hiransuthikul, Thanakit Pongpitakmetha, Sekh Thanprasertsuk, Wanakorn Rattanawong

Get full text

Real-world Bleeding Outcomes and Costs Following Vascular Graft Anastomosis Using PROLENE Sutures with HEMO-SEAL Technology in Patients Undergoing Abdominal Aortic Aneurysm Repair by Nadia Y. Sutton, Niels-Derrek Schmitz

“…**Objectives:** Compare real-world bleeding-related outcomes and costs following vascular anastomosis using PROLENE sutures with HEMO-SEAL technology (HEMO-SEAL sutures) compared with standard PROLENE sutures in patients receiving abdominal aortic aneurysm (AAA) repair in the United States. …”
Get full text

Effectiveness and Safety of the TRIO Optimal Health Management Program in Patients With Type 2 Diabetes Mellitus Initiating Basal Insulin Therapy: Prospective Observational Real-World Study by Chenxi Li, Lixin Guo, Lixin Shi, Li Chen, Liming Chen, Yaoming Xue, Hong Li, Yuzhen Liang, Jing Yang, Weimin Wang, Dalong Zhu

“…ObjectiveThis prospective observational study evaluated the effectiveness and safety of the TRIO optimal health management program for patients with T2DM initiating BI therapy in a real-world setting. MethodsPatients aged 18-85 years with inadequate glycemic control (baseline hemoglobin A1c [HbA1c] ≥7%) starting BI therapy were enrolled in outpatient and inpatient settings. …”
Get full text

The Effects of Oral Semaglutide on Hepatic Fibrosis in Subjects with Type 2 Diabetes in Real-World Clinical Practice: A Post Hoc Analysis of the Sapporo-Oral SEMA Study by Hiroya Kitsunai, Yuka Shinozaki, Sho Furusawa, Naoyuki Kitao, Miki Ito, Hiroyoshi Kurihara, Chiho Oba-Yamamoto, Jun Takeuchi, Akinobu Nakamura, Yumi Takiyama, Hiroshi Nomoto

“…Methods: A secondary analysis of a multicenter, retrospective, observational study investigating the efficacy and safety of oral semaglutide in Japanese subjects with type 2 diabetes in a real-world clinical setting (the Sapporo-Oral SEMA study) was conducted. …”
Get full text

Overall Survival of Patients with Metastatic Renal Cell Carcinoma Following the Introduction of Targeted and Immunotherapies: A Norwegian Retrospective, Real-World Registry Data Study (RECON3) by Puco K, Notland CS, Szulkin R, Jonasson C, Beisland C, Johannesen TB, Solli O, Oldenburg J, Heinrich D

Subjects: “…real-world data…”
Get full text

Characteristics and real-world medication persistence of people living with HIV treated with DTG/3TC or BIC/FTC/TAF: a hospital claims database study in Japan by Rie Kanamori, Nozomi Aoki, Akio Kanazawa, Mayumi Yuda, Nao Makino, Emi Ohata, Nobuyuki Fukui, Hirotake Mori, Hirohide Yokokawa, Toshio Naito

Subjects: Get full text

Visual Acuity Outcomes and Influencing Factors in a Cohort of UK Real-World Diabetic Macular Oedema Patients During the First Two Years of Anti-VEGF Treatment by Qing Wen, Helene Karcher, David M. Wright, Samriddhi Buxy Sinha, Usha Chakravarthy, Catarina Santos, Franklin Igwe, Recivall Salongcay, Katie Curran, Tunde Peto

“…Conclusions: Our study confirms the effectiveness of anti-VEGF treatments in improving or maintaining vision for DMO patients, consistent with previous real-world clinical data. An elder age, a better baseline VA, low annual injection numbers (<5), and less frequent injection intervals (≥12 weeks) were negatively associated with ISVA success in the first two years. …”
Get full text

Methodological challenges using routine clinical care data for real-world evidence: a rapid review utilizing a systematic literature search and focus group discussion by Michelle Pfaffenlehner, Max Behrens, Daniela Zöller, Kathrin Ungethüm, Kai Günther, Viktoria Rücker, Jens-Peter Reese, Peter Heuschmann, Miriam Kesselmeier, Flavia Remo, André Scherag, Harald Binder, Nadine Binder, for the EVA4MII project

Subjects: Get full text

Corrigendum to “Efficacy and Tolerability of Intravenous Ferric Carboxymaltose in Patients with Iron Deficiency at a Hospital Outpatient Clinic: A Retrospective Cohort Study of Real-World Clinical Practice” by António Robalo Nunes, Ana Palricas Costa, Sara Lemos Rocha, Ana Garcia de Oliveira

Get full text