Risk of aortic aneurysm or dissection following use of fluoroquinolones: a retrospective multinational network cohort studyResearch in context by Jack L. Janetzki, Jung Ho Kim, Evan Minty, Jung Ah Lee, Daniel R. Morales, Rohan Khera, Chungsoo Kim, Thamir M. Alshammari, Scott L. DuVall, Michael E. Matheny, Thomas Falconer, Seonji Kim, Thanh-Phuc Phan, Phung-Anh Nguyen, Min-Huei Hsu, Jason C. Hsu, Rae Woong Park, Kenneth K.C. Man, Sarah Seager, Mui Van Zandt, James P. Gilbert, Patrick B. Ryan, Martijn J. Schuemie, Marc A. Suchard, George Hripcsak, Nicole Pratt, Seng Chan You

“…Methods: A retrospective cohort study was conducted using a large, distributed network analysis across 14 databases from 5 countries (United States, South Korea, Japan, Taiwan, and Australia). The study included 13,588,837 patients aged 35 or older who initiated systemic fluoroquinolones (FQs) or comparable antibiotics (trimethoprim with or without sulfamethoxazole [TMP] or cephalosporins [CPHs]) for UTI treatment in the outpatient setting between JAN 01, 2010 and DEC 31, 2019. …”
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Metabolite Profiling and Association Analysis of Leaf Tipburn in Heat-Tolerant Bunching Onion Varieties by Tetsuya Nakajima, Reina Yamamoto, Kanako Matsuse, Masato Fuji, Koei Fujii, Sho Hirata, Mostafa Abdelrahman, Muneo Sato, Masami Yokota Hirai, Masayoshi Shigyo

“…It is consumed year-round in Japan, where a stable supply is essential. However, in recent years, the challenges posed by climate change and global warming have resulted in adverse effects on bunching onions, including stunted growth, discoloration, and the development of leaf tipburn, threatening both crop quality and yield. …”
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Tissue Distribution of Total Flavonoids Extracts of Drynariae Rhizoma in Young and Old Rats by UPLC–MS/MS Determination by Yue Zhang, Xia Lei, Hongdan Xu, Guoliang Liu, Yeqiu Wang, Huifeng Sun, Fang Geng, Ning Zhang

“…Sm. has been extensively used in China, Japan, and Korea to treat osteoporosis and tonify kidneys. …”
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Alginate-Based Hydrogels with Amniotic Membrane Stem Cells for Wound Dressing Application by Fitriani N, Wilar G, Narsa AC, Elamin KM, Wathoni N

“…Nurul Fitriani,1,2 Gofarana Wilar,3 Angga Cipta Narsa,2 Khaled M Elamin,4 Nasrul Wathoni1 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia; 2Pharmaceutical Research and Development Laboratory of FARMAKA TROPIS, Faculty of Pharmacy, Universitas Mulawarman, Samarinda, 75119, Indonesia; 3Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, 45363, Indonesia; 4Graduate School of Pharmaceutical Sciences, Kumamoto University, Chuo-ku, Kumamoto, 862-0973, JapanCorrespondence: Nasrul Wathoni, Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia, Tel/Fax +6222 842 888888, Email nasrul@unpad.ac.idObjective: Chronic wounds are a common clinical problem that necessitate the exploration of novel regenerative therapies. …”
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Genomic analysis of the SMN1 gene region in patients with clinically diagnosed spinal muscular atrophy: a retrospective observational study by Tamaki Kato, Mamoru Yokomura, Yutaka Osawa, Kensuke Matsuo, Yuji Kubo, Taihei Homma, Kayoko Saito

“…Methods This retrospective observational study conducted in Japan used pre-collected DNA samples from patients with clinically diagnosed SMA. …”
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Increased number concentrations of small particles explain perceived stagnation in air quality over Korea by S. Joo, J. Shin, M. Tesche, N. Dehkhoda, T. Kim, Y. Noh

“…Since visibility is influenced by particle size and composition as well as meteorological factors, light detection and ranging (lidar) data provided by the National Institute for Environmental Studies in Japan and PM<span class="inline-formula">_2.5</span> measurements retrieved from AirKorea are used to determine the trends in PM<span class="inline-formula">_2.5</span> mass extinction efficiency (MEE) in Seoul and Ulsan, South Korea, from 2015 to 2020. …”
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INDUSTRIAL POLICY IN ASIAN NEWLY INDUSTRIALIZED COUNTRIES: CONTROVERSIES, REVIEW AND LESSONS by Dejana Gajinov

“…The paper describes the evolution of industrial policy in these countries and what distinguishes them from other developing countries that were unsuccessful in its implementation: the developmental state, which recognized timely the turning point from the strategy of import substitution to the strategy of export promotion, implemented both strategies simultaneously, picked winners, provided support to infant industries through selective interventions, but also disciplined the recipients of its support, tracked its own comparative advantages and anticipated their changes, with a strong synergy between the state and private sectors, and looking at Japan as a model of industrial development, i.e. the lead goose. …”
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Laboratory evaluation of oral fluid for syphilis screening among clinic users from Lima, Peru by Jazmin Qquellon, Silver K. Vargas, Francesca Vasquez, E. Michael Reyes-Diaz, Kelika A. Konda, Carlos F. Caceres, Jeffrey D. Klausner

“…Serum was also tested using RPR (RPR slide test, Wiener Laboratorios SAIC, Argentina) and TPPA (Serodia, Fujirebio Diagnostics Inc., Japan). We assessed oral fluid rapid test overall percent agreement, sensitivity, specificity, and Kappa coefficient against serum SD Bioline Syphilis, TPPA, and RPR. …”
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Efficacy, safety and cost-effectiveness of obinutuzumab in patients with follicular lymphoma: a rapid review by Chao Wang, Yunzhuo Dong, Peng Men, Ruixia Zhang, Ying Xiao, Yishan Bu, Yinpeng Qin, Xinran Zhang, Qianqian Dou, Yiheng Yang, Huier Gao, Yi Zhang

“…The economic researches conducted in China, United States, Japan, Italy and Norway had demonstrated that obinutuzumab-based chemothrepy was cost-effective compared to other chemothrepies. …”
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Biofloc technology significantly reshapes water microbiome and improves survival rates in Japanese eel (Anguilla japonica) by Jiho Yang, Hyunjun Choi, Jun Seong Park, Yehyeon Cha, Ju-Ae Hwang, Seung-Yoon Oh

“…The Japanese eel (Anguilla japonica), consumed as a luxury food item in China, Japan, and South Korea, has seen little research related to BFT. …”
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Phase II trial of nab-paclitaxel plus ramucirumab in combination with nivolumab for unresectable advanced or recurrent gastric cancer after progression on first-line treatment incl... by Hidekazu Hirano, Naoki Takahashi, Yusuke Amanuma, Nobumi Suzuki, Daisuke Takahari, Takeshi Kawakami, Chie Kudo-Saito, Kengo Nagashima, Narikazu Boku, Ken Kato, Hirokazu Shoji

“…Biomarker analyses of serial blood and tumor samples are planned to clarify predictive markers and molecular mechanisms underlying treatment resistance by multifaceted analytical methods (e.g., flow cytometry, DNA sequencing [DNAseq]/RNA sequencing [RNAseq]). …”
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Maternal Satisfaction towards Childhood Immunization Service and Its Associated Factors in Wadla District, North Wollo, Ethiopia, 2019 by Fisha Alebel GebreEyesus, Nega Tezera Assimamaw, Netsanet Tsegaye GebereEgziabher, Bisrat Zeleke Shiferaw

“…During the period of data collection, every questionnaire was cross-checked and the collected data were checked for completeness and consistency on a daily basis. Then, the cleaned data was coded and entered in to Epi Info software version 7.2.2.2 and exported to SPSS software version 23.0 for analysis. …”
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Abortion-related complications in Brazil: results from the World Health Organization Multi-country Survey on Abortion (MCS-A) by Nelio Neves Veiga Junior, Luiz Francisco Cintra Baccaro, Adriana Mendonça da Silva Alexandrino, Alexandre Volta Andrade do Nascimento, Camila Tereza Camilo Clerot, Cintya Andreia do Nascimento Santos, Claudia Lucrécia de Matos Silva, Claudio Lucio de Medeiros Albuquerque, Débora Paulo Santos, Demétrio Antonio Gonçalves da S. Gomes, Édson Cunha de Araújo Junior, Elizabete das Chagas Vilanova, Georgina Costa Teixeira, Graciete Helena Nascimento dos Santos, Guilherme Augusto Guerra Avelar, Iara Elce Lopes Barros, Jaqueline Polon Abboud, Jeane Cristina Antas Lins, Joanne Thalita Pereira Silva, Kelma H. Aguiar de Lucena, Lara Wanderley Paes Barbosa, Lia Ferreira Caixeta Barreto de Siqueira, Luciana de Melo Freitas Carneiro, Lucila Nagata, Márcia de Oliveira Pereira Lúcio, Maria Cleane Rodrigues da Silva, Maria da Conceição Ribeiro Simões, Maria Fernanda da Mota Magalhães, Mariana Viana Almeida, Michelle Regina Faria Lira, Nádia Martins de Paula Souza, Rafael Martins Papa, Rafael Ribeiro Matos, Renata Porto Pinheiro, Roberta Souza dos Anjos, Suelen Miranda de Jesus, Tedy Roger Flores Ynturias, Valéria Cristina Gonçalves, Viviane Resende de Abreu Caetano

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CRYO-NIVAL MODELING SYSTEM. CASE STUDY: BUCEGI MOUNTAINS AND FĂGĂRAŞ MOUNTAINS by ALEXANDRU NEDELEA, RĂZVAN OPREA, FLORIN ACHIM, LAURA COMĂNESCU

“…Le climat actuel des prairies alpines est plus doux que celui pléistocène, quand les glaciers aient occupé les origines des vallées de ces massifs, mais en comparaison avec cela des surfaces plus basses, il est pourtant rude et humide, défavorable au développementdes forêts. …”
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Prediksi Kelulusan Tepat Waktu Berdasarkan Riwayat Akademik Menggunakan Metode K-Nearest Neighbor by Imam Riadi, Rusydi Umar, Rio Anggara

“…The research phase begins with data collection, attribute selection, data cleaning, data transformation, selection of testing data and training data. …”
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In-Situ Electrospinning Dressings Loaded with Kaempferol for Reducing MMP9 to Promote Diabetic Ulcer Healing by Li J, Meng H, Guo W, Zhou L, Wu S, Gao G, Liu Q, You D, Qu W

“…Jianwen Li,1,2,&ast; Hongqi Meng,3,&ast; Wenlai Guo,3 Lubin Zhou,4 Siyu Wu,3 Guanghui Gao,4 Quanzhe Liu,3 Di You,5 Wenrui Qu2,3 1Gastroenteric Medicine and Digestive Endoscopy Center, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 2Joint International Research Laboratory of Ageing Active Strategy and Bionic Health in Northeast Asia of Ministry of Education, Changchun, 130041, People’s Republic of China; 3Department of Hand Surgery, the Second Hospital of Jilin University, Changchun, 130041, People’s Republic of China; 4Polymeric and Soft Materials Laboratory, Advanced Institute of Materials Science, School of Chemical Engineering, Changchun University of Technology, Changchun, 130012, People’s Republic of China; 5Department of Anesthesiology, China-Japan Union Hospital of Jilin University, Changchun, 130012, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Di You; Guanghui Gao, Email youdi1118@jlu.edu.cn; ghgao@ccut.edu.cnBackground: Diabetic foot ulcers (DFUs) are often associated with persistent inflammatory response, impaired macrophage polarization, and slow vascular regeneration. …”
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ETIKOS PAGRINDIMO PROBLEMA POSTMODERNIOJOJE KULTŪROJE by Jūratė Micevičiūtė

“…Habermaso diskursyvioji etika, pasinaudojusi tokiais praėjusio amžiaus mąstymo laimėjimais kaip pagarba asmens orumui ir laisvei bei dialogo filosofija, kuri remiasi ne individualistine, bet solidarumo antropologija. Ispanė A. Cortina papildė šią teoriją svarstymu apie praktinį jos pritaikomumą - minimumų etikų samprata. …”
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ALTERNATYVI MODERNYBĖ IR JOS STRATEGIJOS by Arūnas Gelūnas

“…The final part of the article presents some aspects of the reactions to modern science and rationality by a Non-Western society, namely that of Meiji Japan. The philosophy of "first Japanese philosopher" - Kitaro Nishida - is briefly examined. …”
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Lymphadenopathies: A Retrospective Study of Epidemiology, Characteristics, Diagnosis and Treatment Outcomes of Patients in a Tertiary Hospital in Mogadishu-Somalia by Kıratlı K, Bulut M, Ali MA, Aysin M, Ali AM, Mohamed Hirsi I, Bashir AM

“…Kaz&inodot;m K&inodot;ratl&inodot;,1 Muhammet Bulut,2 Mukhtar Abdullahi Ali,1 Murat Aysin,3 Ahmed Mohamed Ali,1 Ibrahim Mohamed Hirsi,4 Ahmed Muhammad Bashir5 1Mogadishu Somalia Turkey Recep Tayyip Erdo&gbreve;an Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Mogadishu, Somalia; 2Sancaktepe &Scedil;ehit Prof. Dr. Ilhan Varank Training and Research Hospital, Department of Radiology, Istanbul, Turkey; 3Balikesir University Faculty of Medicine, Department of Public Health, Balikesir, Turkey; 4Mogadishu Somalia Turkey Recep Tayyip Erdo&gbreve;an Training and Research Hospital, Department of Pediatrics, Mogadishu, Somalia; 5Mogadishu Somalia Turkey Recep Tayyip Erdo&gbreve;an Training and Research Hospital, Department of Internal Medicine, Mogadishu, SomaliaCorrespondence: Kaz&inodot;m K&inodot;ratl&inodot;, Mogadishu Somalia Turkey Recep Tayyip Erdo&gbreve;an Training and Research Hospital, Department of Infectious Diseases and Clinical Microbiology, Mogadishu, Somalia, Email drkazimkiratli@gmail.comIntroduction: Lymphadenopathies, which can be caused by infections, malignant diseases, autoimmune disorders, and many other diseases, pose a challenge to clinicians in sub-Saharan Africa, as well as all over the world. …”
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Analisis Kadar Kreatinin Serum Sebelum dan Setelah Terapi Tenovofir pada Penyandang HIV di RS Dr. M. Djamil Padang Periode 2012-2013 by Regina Ivanovna, Efrida ., Roza Kurniati

“…Pada hasil penelitian, didapatkan perbedaan rata-rata kadar kreatinin serum yang bermakna sebelum dan setelah terapi tenofovir sebesar 0,7± 0,2 mg/dLdan 0,9 ± 0,5 mg/dL (P&lt;0,05). Dapat disimpulkan bahwa terdapat peningkatan kreatinin serum setelah terapi tenofovir pada penyandang HIV.…”
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