Incidence of HTLV-1-associated myelopathy in the UK from 1991 to 2024: a longitudinal observational cohort study by Carolina Rosadas, Jerico Baylon, Claire Greiller, Adine Adonis, Divya Dhasmana, Nicholas W. S. Davies, Graham P. Taylor, Graham P. Taylor

“…There are limited data on the incidence of HAM, with higher rates seen in Latin America and the Caribbean compared to Japan. We investigated the incidence of HAM in a cohort of initially asymptomatic people with HTLV-1 in the United Kingdom (UK).MethodsThis is a longitudinal retrospective observational study of people with confirmed HTLV-1 infection who first attended the National Centre for Human Retrovirology in London, UK, between 1st March 1991 and 31st March 2024. …”
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Do you have enough space? Habitat selection of insectivorous cave-dwelling bats in fragmented landscapes of Eastern Amazon. by Valéria da C Tavares, Mariane S Ribeiro, Xavier Prous, Alice A Notini, Nathalia Y Kaku-Oliveira, Leandro M D Maciel, Sérgio Sales, Juliana M Longo, Flávia M Evangelista, Lucas Rabelo, Iuri V Brandi, Santelmo S Vasconcelos, Sonia S Talamoni, Guilherme Oliveira, Leonardo C Trevelin

“…We investigated habitat selection by cave bats in a mosaic of Amazonian forests, iron-rich savannas and iron-caves, studying the movements of the aerial insect-catcher Furipterus horrens (Furipteridae) and of the foliage gleaning bat Lonchorhina aurita (Phyllostomidae), both cave-dependent in the area. …”
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Incidence and risk factors for Graves’ orbitopathy in patients who underwent anti-inflammatory and immunosuppressive treatment during medical treatment for Graves’ disease: investi... by Natsuko Watanabe, Jaeduk Yoshimura Noh, Ai Kozaki, Ran Yoshimura, Ai Yoshihara, Nami Suzuki, Masako Matsumoto, Miho Fukushita, Aya Kinoshita, Azusa Aida, Hideyuki Imai, Shigenori Hiruma, Toshu Inoue, Kosuke Inoue, Kiminori Sugino, Koichi Ito

“…This study aimed to clarify the incidence and risk factors for GO treated with AIIST and propose a predictive score, among newly diagnosed Graves’ disease (GD) patients in Japan. A total of 1,553 GD patients who were newly diagnosed during the year 2011 were investigated. …”
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Long-term impact of molecular epidemiology shifts of methicillin-resistant Staphylococcus aureus on severity and mortality of bloodstream infection by Norihito Kaku, Masaki Ishige, Go Yasutake, Daisuke Sasaki, Kenji Ota, Fujiko Mitsumoto-Kaseida, Kosuke Kosai, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara

“…A 2019 nationwide study in Japan revealed the predominant methicillin-resistant Staphylococcus aureus (MRSA) types in bloodstream infections (BSIs) to be sequence type (ST)8-carrying SCCmec type IV (ST8-MRSA-IV) and clonal complex 1-carrying SCCmec type IV (CC1-MRSA-IV). …”
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European Working Time Directive and doctors’ health: a systematic review of the available epidemiological evidence by Consol Serra, Evangelia Demou, Ewan B Macdonald, Sergio Vargas-Prada, Maria Cruz Rodriguez-Jareño, Kaveh A Sanati, Alenka Škerjanc, Pedro G Reis, Ritva Helimäki-Aro

“…From these, 11 studies of high or intermediate quality carried out in North America, Europe and Japan met the inclusion criteria. Six studies included medical residents, junior doctors or house officers and the five others included medical specialists or consultants, medical, dental, and general practitioners and hospital physicians. …”
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AOZORA: long-term safety and joint health in paediatric persons with haemophilia A without factor VIII inhibitors receiving emicizumab – protocol for a multicentre, open-label, pha... by Seitaro Yoshida, Masashi Taki, Hideyuki Takedani, Midori Shima, Keiji Nogami, Azusa Nagao, Haruko Yamaguchi-Suita, Yui Kyogoku, Akira Ishiguro, Kaoru Kitsukawa

“…The AOZORA study will evaluate the long-term safety and joint health of paediatric PwHA without factor (F)VIII inhibitors taking emicizumab; here, we report the details of the study protocol and baseline data.Methods and analysis AOZORA is a multicentre, open-label, phase IV clinical study in Japan that aims to enrol approximately 30 PwHA aged <12 years without FVIII inhibitors. …”
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Egg freshness during storage: the effect of laying hen age and shelf life prediction using a novel hybrid modeling method by Yifeng Lu, Jing Li, Zihao He, Linyun Chen, Huixin Tian, Chen Xu, Xinglian Xu, Minyi Han

“…Factors such as temperature, relative humidity, the operation of cleaning, and microorganisms have been shown to play a role in the storage quality of eggs. …”
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Mental health help-seeking knowledge, attitudes and behaviour among male elite rugby players: the role of masculine health-related values by Simon M Rice, John L Oliffe, Yasutaka Ojio, Rei Amemiya

“…The study aimed to investigate how masculine health-related values measured by the Intentions Masculine Values Scale (IMVS) affect help-seeking behaviours among male elite rugby players.Methods A cross-sectional survey was conducted among 220 Japanese male elite rugby players in the Japan Rugby League One (response rate: 40.6%). Participants completed an online survey assessing help-seeking knowledge, attitudes and behaviours, along with masculine health-related values using the IMVS. …”
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Epigenetic alterations of 11beta-hydroxysteroid dehydrogenase 1 gene in the adipose tissue of patients with primary aldosteronism by Yoshimichi Takeda, Masashi Demura, Mitsuhiro Kometani, Shigehiro Karashima, Daisuke Aono, Seigo Konishi, Shin-ichi Horike, Makiko Meguro-Horike, Takashi Yoneda, Yoshiyu Takeda

“…PA, SCS, and Cu were diagnosed according to the guideline of the Japan Endocrine Society. The mRNA level of HSD11B1 was quantified using real-time PCR. …”
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Effect of video-based trauma-informed care training for nursing staff on seclusion and restraint of psychiatric inpatients: A non-randomized controlled study by Michi Miyake, Megumi Hazumi, Kentaro Usuda, Takahiro Kawashima, Maiko Fukasawa, Hisateru Tachimori, Daisuke Nishi

“…Methods: Six of the 11 participating hospitals interested in trauma-informed care training were allocated to the intervention group, while the remaining five were assigned to the control group.The intervention ran from November 2021 to January 2022 in Japan. Data were collected using a specialized psychiatric monitoring system from April 2020 to October 2021 pre-intervention and from February 2022 to January 2023 post-intervention. …”
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<i>Allosaurus europaeus</i> (Theropoda: Allosauroidea) Revisited and Taxonomy of the Genus by André Burigo, Octávio Mateus

“…The genus is distributed in occurrences from the United States, Germany, and Portugal, and from the Late Kimmeridgian to the Late Tithonian, while the Cenomanian report from Japan is reidentified as <i>Segnosaurus</i>.…”
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Leveraging generative adversarial networks for data augmentation to improve fault detection in wind turbines with imbalanced data by Subhajit Chatterjee, Yung-Cheol Byun

“…Nevertheless, a formidable challenge arises from the need for more fault information gleaned from small fault data samples, resulting in data insufficiency and imbalance issues. …”
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A single-center, single-arm, prospective, open-label, and comparative trial to evaluate the safety and tolerability profile of a 90-day oral L-arginine hydrochloride intervention f... by Hiroyuki Naito, Masahiro Nakamori, Megumi Toko, Yuki Hayashi, Taku Tazuma, Tomoaki Watanabe, Keito Ishihara, Keisuke Tachiyama, Yu Yamazaki, Hirofumi Maruyama

“…Trial Registration number: Japan Registry of Clinical Trials (jRCTs061230001), first registered 11/04/2023.…”
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Defining New Research Questions and Protocols in the Field of Traumatic Brain Injury through Public Engagement: Preliminary Results and Review of the Literature by Shumaila Hasan, Aswin Chari, Mario Ganau, Chris Uff

“…Brain tissue sampling is the mainstay of diagnosis in neuro-oncology; following on this path, we hypothesise that information gleaned from neural tissue samples obtained in TBI patients upon hospital admission may correlate with outcome data in TBI patients, enabling an early, accurate, and more comprehensive pathological classification, with the intent of guiding treatment and future research. …”
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Single-arm multicenter phase II study on aggressive local consolidative therapy in combination with systemic chemotherapy for stage IV non-small cell lung carcinoma with oligometas... by Takaaki Tokito, Kazuhiko Yamada, Hidenobu Ishii, Yuichi Takiguchi, Go Saito, Koichi Minato, Hisao Imai, Hiroshi Tanaka, Satoru Miura, Kageaki Watanabe, Yoshifusa Koreeda, Akira Ono, Naoki Furuya, Toshihiro Misumi, Kazushige Hayakawa, Etsuyo Ogo, Hiroaki Okamoto

“…Clinical trial registration: University Hospital Medical Information Network, Japan (protocol identification number: UMIN000022431, first registration date: 01/JUN/2016).…”
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Exploring associations of financial well-being with health behaviours and physical and mental health: a cross-sectional study among US adults by Kai McKeever Bullard, Carla Mercado, Michele L F Bolduc, Desmond Banks, Courtni Andrews, Zoe R F Freggens, Rashid Njai

“…With increasing time since the last health service visit or screening, FWB was increasingly lower compared with adults with visits or screenings &lt;1 year (≥10 years or ‘never’, FWB ranged from −1 (blood sugar check) to −6.5 (dental examination/cleaning) points). FWB was lower with declining general health status (excellent (reference), very good (−0.5 points), good (−3.4 points) and fair/poor (−6.6 points)). …”
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In silico methods for immunogenicity risk assessment and human homology screening for therapeutic antibodies by Aimee E. Mattei, Andres H. Gutierrez, Soorya Seshadri, Jacob Tivin, Matt Ardito, Amy S. Rosenberg, William D. Martin, Anne S. De Groot

“…To facilitate larger scale analyses and accelerate preclinical immunogenicity risk assessment, our group developed an integrated web-based platform called ISPRI, (Immunogenicity Screening and Protein Re-engineering Interface) that provides hands-on access through a secure web-based interface for scientists working in large and mid-sized biotech companies in the US, Europe, and Japan. This toolkit has evolved and now contains an array of algorithms that can be used individually and/or consecutively for immunogenicity assessment and protein engineering. …”
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Cohort profile: the East London Health and Care Partnership Data Repository: using novel integrated data to support commissioning and research by George Howard, Kamaldeep Bhui, Amy Ronaldson, Evangelos Chandakas, Qiongwen Kang, Katie Brennan, Aminat Akande, Irene Ebyarimpa, Eleanor Wyllie, Richard Fradgley, Mark Freestone

“…Data completeness for risk factors (eg, blood pressure, cholesterol) was high in patients with long-term conditions.Future plans The data are being further cleaned and evaluated using imputation, Bayesian and economic methods, principally focusing on specific cohorts, including type II diabetes, depression and personality disorder. …”
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Epidemiology of Liver Cancer in Europe by F Xavier Bosch, Josepa Ribes

“…Areas of highest rates include Eastern and South Eastern Asia, Japan, Africa and the Pacific Islands (LC age-adjusted incidence rates [AAIRs] ranging from 17.6 to 34.8). …”
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Effect of Instituting Upper Limits for Chest Compression Depth for Laypersons at Six-months After Chest Compression-Only Training: A Randomized Controlled Simulation Study

“…Considering the situation of out-of-hospital cardiac arrest in Japan, studies focusing on compression depths in another aged people should be considered.…”
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