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1061
Malícia honey (Mimosa quadrivalvis L.) produced by the jandaíra bee (Melipona subnitida D.) shows antioxidant activity via phenolic compound action in obese rats
Published 2025-02-01“…This study aimed to evaluate whether administration of Mimosa quadrivalvis L. honey to obese rats could reduce oxidative stress in vital organs through phenolic compound action.MethodsWistar rats (228 ± 14.69 g) were randomly divided into two groups: a healthy group (HG, n = 20) fed a control diet and an obese group (OG, n = 20) fed a cafeteria diet for the initial 8 weeks. …”
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1062
Development and validation of an LC-MS/MS method for the simultaneous estimation of tadalafil and macitentan in rat plasma: Greenness assessment and design of experiment approach
Published 2025-03-01“…Pharmacokinetic studies in male Wistar rats (tadalafil: 0.0033 mg/kg; macitentan: 0.0003 mg/kg) revealed distinct absorption and elimination profiles. …”
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1063
Glucagon-Like Peptide-2 Analogue ZP1849 Augments Colonic Anastomotic Wound Healing
Published 2020-01-01“…Methods. Eighty-seven male Wistar rats were stratified into four groups and received daily treatment with vehicle or ZP1849 starting one day before (day -1) end-to-end anastomosis was constructed in the left colon on day 0, and on days 0 (resected colon segment), 3, and 5, gene expressions of GLP-2R, Ki67, insulin-like growth factor- (IGF-) 1, type I (COL1A1) and type III (COL3A1) procollagens, cyclooxygenase- (COX-) 1, COX-2, and matrix metalloproteinase- (MMP-) 7 were quantified by RT-qPCR. …”
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1064
Investigating the neuroprotective effects of Dracocephalum moldavica extract and its effect on metabolomic profile of rat model of sporadic Alzheimer's disease
Published 2025-02-01“…The antioxidant potential of the extract was evaluated by 2,2-Diphenyl-1-picrylhydrazyl and nitric oxide radical scavenging assays. Male Wistar rats were injected with STZ (3 mg/kg, single dose, bilateral ICV) to induce a sporadic AD (sAD) model. …”
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1065
Fermented sugarcane juice-derived probiotic Levilactobacillus brevis RAMULAB54 enhances lipid metabolism and glucose homeostasis through PPAR-γ activation
Published 2025-01-01“…Organic acid interactions with PPAR-γ were evaluated via molecular docking, while cytotoxicity and adipocyte differentiation in 3T3-L1 cells were tested using MTT assays, Oil Red O staining, triglyceride quantification, and qRT-PCR. In vivo, male Wistar rats in hyperlipidemic and streptozotocin-induced hyperglycemic models were treated with LB13243 for 4 weeks, followed by analysis of food intake, body weight, serum glucose, lipids, and histopathology. …”
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1066
Curative Effect of AD-MSCs against Cisplatin-Induced Hepatotoxicity in Rats is Potentiated by Azilsartan: Targeting Oxidative Stress, MAPK, and Apoptosis Signaling Pathways
Published 2023-01-01“…After characterization and labeling of AD-MSCs by PKH26 dye, 54 Wistar male albino rats were randomly divided into nine groups: I (CONT), II (AZIL.H), III (CISP), IV (CISP + AZIL.L), V (CISP + AZIL.H), VI (CISP + AD-MSCs), VII (CISP + AZIL.L + AD-MSCs), VIII (CISP + AZIL.H + AD-MSCs), and IX (CISP + VITA C). …”
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1067
Circadian Rhythms Fluctuate the Treatment Effects of Intravesical Treatments on Rat Urinary Frequency Models
Published 2024-01-01“…Nine eleven-week-old female Wistar rats were divided into three groups to receive intravesical instillation of 0.1% acetic acid (AA), 1.0% AA, or phosphate-buffered saline (PBS). …”
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1068
Effects of yacon on carbohydrates and lipid metabolism, oxidative-nitrative stress markers changes in rats with experimental metabolic syndrome
Published 2025-01-01“…Experimental procedure: In the study were used male Wistar white rats, in which metabolic syndrome was induced by consuming a 10 % fructose solution. …”
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1069
Effects of Curcumin on Iron Overload in Rats
Published 2021-12-01“…This study investigated the effects of curcumin on iron overload in rats. Methods: Forty male Wistar rats weighing 139.78 ± 11.95 gm (Mean ± SD) were divided into three equal groups: (i) controls; (ii) iron overload group that received six doses of iron dextran 1000 mg/kg–1 by intraperitoneal injections (i.p.); and (iii) iron overload curcumin group that received six doses of curcumin (1000 mg/kg BW by i.p.). …”
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1070
Estrés oxidativo en ratas envejecidas
Published 2013-12-01“…<strong><br />Métodos:</strong> se seleccionaron un total de 20 ratas Wistar machos con un peso aproximado entre 200 y 250 gramos, para conformar dos grupos con 10 ratas adultas jóvenes y 10 ratas adultas. …”
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1071
Transgenerational effect of prenatal stress on behavior and lipid peroxidation in brain structures of female rats during the estral cycle
Published 2024-07-01“…The effect of stress in pregnant female Wistar rats on the behavior and lipid peroxidation (LP) in the neocortex, hippocampus and hypothalamus in the female F2 generation during the ovarian cycle was investigated. …”
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1072
Hyperbaric oxygen potentiates platelet-rich plasma composition and accelerates bone healing
Published 2025-03-01“…A closed femur fracture model was established in male Wistar rats, with treatments of hPRP or nPRP administered around the fracture site immediately post-fracture and on days 7, 14, 21, and 28. …”
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1073
Study on the Genetic Differences in Reservoir Characteristics Based on the Bidirectional Provenance of the Yanchang Formation in the Jiyuan Area, Ordos Basin, China
Published 2022-01-01“…Combined with the nature of the basement of the basin and the characteristics of the present structure, it is believed that the Jiyuan area is located in the central and western parts of the basin, spanning two first-level structural units, the Tianhuan Depression and the Yishan Ramp. This special geographical location makes Jiyuan area affected by bidirectional provenance. …”
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1074
The Response of the Pulp-Dentine Complex, PDL, and Bone to Three Calcium Silicate-Based Cements: A Histological Study in an Animal Rat Model
Published 2020-01-01“…An experimental lateral root perforation with pulp exposure was performed in 32 lower incisors of 16 male Wistar albino rats. They were randomly assigned into three test groups (each including eight teeth) that were filled either by Biodentine (BD) or MicroMega mineral trioxide aggregate (MM-MTA) or EndoSequence root repair material putty (ESRRM putty), besides eight unperforated incisors from the other four rats (control group). …”
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1075
Mas Receptor Blockade Promotes Renal Vascular Response to Ang II after Partial Kidney Ischemia/Reperfusion in a Two-Kidney-One-Clip Hypertensive Rats Model
Published 2021-01-01“…Thirty-seven 2K1C male Wistar rats with systolic blood pressure ≥150 mmHg were randomly divided into three groups; sham, IR, and IPC + IR. …”
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1076
Investigating the Effect of Testosterone Supplement on Heart and Muscle Damage in Rats Applied with Swimming Exercise
Published 2019-04-01“…The study was conducted on 30 day-old 27 (Wistar, male) rats that were supplied from “Selçuk University Experimental Medicine Research and Application Center”. …”
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1077
Investigating the preventive effects of pulsed electromagnetic fields on glucocorticoid-induced osteoporosis in rats
Published 2025-01-01“…A total of seventy-two adult male Wistar rats composed the experimental group and were subsequently assigned to three groups for treatment. (1) On the first day (day 0), 24 rats in the PEMF group were intravenously injected with lipopolysaccharide (LPS) at a concentration of 10 μg/kg. …”
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1078
The influence of monosodium glutamate on the development of oxidative-nitrosative stress in the large cerebral hemispheres of rats under the combination of a change in the “light-d...
Published 2024-06-01“…The research was carried out on 72 white Wistar rats weighing 150–200 of different sexes, divided into 5 groups: control (n = 15), AD (n = 13), SIR (n = 15), a combination of SIR and AD (n = 14), a combination of SIR, AD, and glutamate (n = 15). …”
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1079
Hypoglychemic activity of Moringa oleifera extract in streptozotocin-induced diabetic rats
Published 2024-08-01“…Method: Healthy male Wistar rats (weight 200-300 g, aged 9-11 weeks) were used in the experiment. …”
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1080
The potential of aloe vera gel utilization for skin wound healing in rats based on GC–MS and HPLC chemical profile
Published 2025-01-01“…The study aimed to evaluate wound healing of aloe vera gel as raw or ethanol extract on a dorsal full thickness circular wound in Wistar rats. Rats subjected to the excision surgery were grouped into: control (+ ve), without treatment. and Kenacomb, aloe raw gel and aloe ethanol extract applied groups for 3, 7, 14 and 21 days for treatment evaluation. …”
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