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1041
Various endurance training intensities improve GFR and Up-regulate AQP2/GSK3β in lithium-induced nephropathic rats
Published 2025-02-01“…Methods Thirty-five male Wistar rats were divided into five groups: control, lithium-only, lithium with low-intensity exercise (LIT), lithium with medium-intensity exercise (MIT), and lithium with high-intensity exercise (HIT). …”
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1042
Сhanges in subcellular distribution of lysosomal cysteine proteinases activity in parenchymatous organs of rats under the action of nitric oxide synthesis modulators
Published 2018-09-01“…The object of study – male rats Wistar line, the material was the cytoplasmic and lysosomal fraction of homogenates of liver, kidney, lung tissues. …”
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1043
The effect of silymarin on ischemia-reperfusion injury in skeletal muscles of rats
Published 2024-03-01“…Material and Methods: We used 18 male Wistar albino rats weighing 225-275 g. Each of the three groups of rats [Control (C), Ischemia-Reperfusion (I/R), and Silymarin-Ischemia/Reperfusion (S-I/R)] consisted of six rats. …”
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1044
Protective Effect of High-Intensity Interval Training (HIIT) and Moderate-Intensity Continuous Training (MICT) against Vascular Dysfunction in Hyperglycemic Rats
Published 2022-01-01“…Twenty-four eight-week-old male Wistar rats were randomly assigned into four groups: healthy nonexercising control (C), hyperglycemic control (HG-C), hyperglycemic + HIIT (HG-IT), and hyperglycemic + MICT (HG-CT). …”
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1045
Involvement of RBP4 in Diabetic Atherosclerosis and the Role of Vitamin D Intervention
Published 2018-01-01“…The purposes of this study were to evaluate the expression of retinol-binding protein 4 (RBP4) in diabetic rats with atherosclerosis and to investigate the role of vitamin D intervention. Male Wistar rats were randomly divided into 4 groups, including the control group (NC), the diabetic rats (DM1), the untreated diabetic atherosclerosis rats (DM2), and the vitamin D-treated diabetic atherosclerosis rats (DM3). …”
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1046
Potensi Ekstrak Kunyit (Curcuma longa) Terhadap Kadar Ischemia Modified Albumin (IMA) pada Tikus Model Penyakit Jantung Koroner
Published 2020-11-01“…Metode: Desain penelitian ini adalah rancangan post-test only control group dengan menggunakan tikus wistar jantan sebanyak 30 ekor yang terbagi ke dalam 5 kelompok yaitu, kelompok 1 kontrol negatif, kelompok 2 kontrol positif, kelompok perlakuan 1, 2, dan 3. …”
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1047
Molecular evidence of the inhibitory potential of melatonin against sodium arsenite toxicity
Published 2025-02-01“…Methods: Forty-eight adult healthy male wistar rats aged 7–8 weeks were divided into eight for this research. …”
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1048
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding
Published 2023-01-01“…The present study was to examine whether miR-145 modulates phenotypic transformation of VSMCs under normal state and synthetic state and to explore the possible role of ADAM17-mediated ACE2 shedding and ACE2-Ang-(1–7)-Mas receptor axis. Wistar rats were fed with high-sucrose/high-fat diet for 30 weeks to establish a metabolic hypertension animal model. …”
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1049
New methods of local medical treatment of purulent wounds
Published 2020-06-01“…The material was in vitro studies and experimental animals (Wistar rats), which was modeled a purulent wound and then divided into 3 groups according to the treatment method with the three studied combinations, each of which contained benzalkonium chloride and metronidazole, the combinations differed in bases, which were polyethylene oxide or sodium salt of carboxymethylcellulose, or polymethylsiloxane polyhydrate. …”
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1050
The Effect of Lipotoxicity on Renal Dysfunction in a Nonobese Rat Model of Metabolic Syndrome: A Urinary Proteomic Approach
Published 2019-01-01“…In this study, we investigated the manifestation of renal lipid accumulation and its effect on renal dysfunction in a model of metabolic syndrome—the hereditary hypertriglyceridemic rat (HHTg)—by assessing microalbuminuria and targeted urinary proteomics. Male Wistar control rats and HHTg rats were fed a standard diet and observed over the course of ageing at 3, 12, and 20 months of age. …”
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1051
Efectos del ácido fólico sobre el crecimiento de la descendencia de ratas tratadas con alcohol
Published 2013-07-01“…<br /><strong>Métodos:</strong> se utilizaron 24 ratas Wistar gestantes, divididas en cuatro grupos: A: control, B: tratadas con ácido fólico, C: tratadas con etanol y D: tratadas con etanol y ácido fólico. …”
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1052
Metabolic Effects of Testosterone Hormone Therapy in Normal and Orchiectomized Male Rats: From Indirect Calorimetry to Lipolytic Enzymes
Published 2019-01-01“…In total, thirty-two male Wistar rats (300–400 g) were divided into four groups (n = 8/group), including (a) sham-operated and vehicle-injected group (Sham), (b) T-treated sham group (T-Sham) for which sham-operated rats were injected with IM testosterone undecanoate (100 mg/kg, for one week), (c) orchiectomy and vehicle-injected group (Orch), and (d) T-replaced orchiectomy group (T-Orch). …”
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1053
CircRNA-miRNA-mRNA regulatory network in high-altitude hypobaric hypoxia-induced hearing impairment and hearing acclimatization
Published 2025-03-01“…To decipher transition-related circular RNAs (circRNAs)-microRNAs (miRNAs)-messenger RNA (mRNAs) regulatory network. Methods: Wistar rats were airlifted from plain to high altitude and maintained for 30 days and 60 days. …”
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1054
Shen Shuai II recipe improves renal hypoxia to attenuate renal injury in 5/6 renal ablation/infarction rats and effect evaluation using blood oxygenation level-dependent functional...
Published 2024-12-01“…This study aimed to explore the effect of SSR on renal hypoxia and injury in CKD rats.Methods Twenty-five Wistar rats underwent 5/6 renal ablation/infarction (A/I) surgery were randomly divided into three groups: 5/6 (A/I), 5/6 (A/I) + losartan (LOS), and 5/6 (A/I) + SSR groups. …”
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1055
Combination of Mangosteen (Garcinia mangostana L.) Pericarp Extract and Physical Exercise Decreases Atherosclerotic Lesions in Atherogenic Diet-Fed Rats
Published 2024-12-01“…This study aimed to investigate the effect of MP extract combined with PE on atherosclerotic changes in rats fed an atherogenic diet. Twenty-five male Wistar rats (Rattus norvegicus) aged 6-8 weeks were randomly divided into five groups of five rats each: C (control, normal diet), CH (atherogenic diet), T1 (atherogenic diet plus MP extract 800 mg/kg/day in three divided doses with PE), T2 (atherogenic diet plus MP extract-loaded nanoemulsion 50 mg/kg/day with PE), and T3 (atherogenic diet plus atorvastatin 1.44 mg/day with PE). …”
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1056
INTENSITY OF OXIDATIVE STRESS DEVELOPMENT IN RAT MAJOR CEREBRAL HEMISPHERES UNDER COMBINED CONDITIONS OF SYSTEMIC INFLAMMATORY RESPONSE, CHANGES IN THE NORMAL LIGHT-DARK CYCLE, AN...
Published 2024-07-01“…The study was conducted on 44 white Wistar rats weighing 150-200 kg of various articles, divided into 3 groups: control (15), a combination of AD and SIR (14), and a combination of AD, SIR, and fluoxetine (15). …”
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1057
Nose-to-Brain Delivery of Chitosan-Grafted Leciplexes for Promoting the Bioavailability and Antidepressant Efficacy of Mirtazapine: In Vitro Assessment and Animal Studies
Published 2025-01-01“…Then, the determined optimum formulation was coated with chitosan (CS-MRZ-LPX) and utilized in pharmacodynamics investigations and in vivo biologic distribution studies in Wistar male rats. <b>Results</b>: The customized MRZ-LPX formulation had a diameter size of 186.2 ± 3.5 nm and drug EE of 45.86 ± 0.76%. …”
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1058
Effects of Quetiapine on Novelty‐Related Object Recognition Memory and Hippocampal BDNF Level in Sleep‐Deprived Rats
Published 2025-01-01“…Materials and Methods A total of 42 adult male Wistar albino rats were assigned into six experimental groups: non‐sleep‐deprived (NSD) control, short‐term control group (n = 7) received a single intraperitoneal (i.p.) injection 10 mg/kg QET of 1 mL saline (4 days) (NSD‐STQET), long‐term control group (n = 7) received single i.p. injection 10 mg/kg QET of 1 mL saline (30 days) (NSD‐LTQET); 72 h sleep‐deprived (SD) group, 72 h SD short‐term group received short‐term i.p. injection 10 mg/kg QET of either (n = 7) (SD‐STQET), and 72 h SD long‐term group received long‐term i.p. injection 10 mg/kg QET of either (n = 7) QET (SD‐LTQET). …”
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1059
A systematic review of the worldwide prevalence of survivors of poliomyelitis reported in 31 studies
Published 2017-07-01“…We aim to undertake a systematic review of all literature concerning the prevalence of survivors of poliomyelitis.Methods Electronic databases were searched from 1900 up to May 2016 for peer-reviewed studies using a population-based approach witha defined denominator and some form of diagnostic or clinical verification of polio. …”
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1060
Elevated Serum Levels of the Antiapoptotic Protein Decoy-Receptor 3 Are Associated with Advanced Liver Disease
Published 2016-01-01“…In patients with CVH, sDcR3 significantly correlated to fibrosis severity, as estimated by Ishak score (P=0.019) or by liver stiffness measured with elastography (Spearman r=0.698, P<0.001). …”
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