Peritoneal lavage with sterile water reduces IL-1 levels and postoperative adhesions following laparotomy in rats by Ryan Fernandi, I Ketut Sudartana, Made Agus Dwianthara Sueta, I Made Mahayasa, Ketut Putu Yasa, I Gusti Agung Bagus Krisna Wibawa

“…In this post-test control group study, 20 adult Wistar rats were subjected to laparotomy before being randomly divided into two groups to receive either intraperitoneal lavage with normal saline (0.9% NaCl) or sterile water. …”
Get full text

An Effective Phytoconstituent Aconitine: A Realistic Approach for the Treatment of Trigeminal Neuralgia by Dilek Çankal, Esra Küpeli Akkol, Yeliz Kılınç, Mert İlhan, Raffaele Capasso

“…Infraorbital nerve chronic constriction injury was performed in adult Wistar Albino rats. After the neuropathic pain developed, the rats were assigned to one of the treatment groups: carbamazepine 40 or 80 mg/kg; aconitine 0.25, 0.50, or 0.75 mg/kg; or saline injection (control group). …”
Get full text

Phytochemical screening and anti-Helicobacter pylori activity of Bryophyllum pinnatum, Ocimum gratissimum and Vernonia amygdalina by Precious Egharevba, Emilia Igue, Kingsley Enerijiofi, Orhue Amengialue

“…The in-vivo study as carried out using Wistar albino rats demonstrated the promising therapeutic effect of the plants extract against Helicobacter pylori infection. …”
Get full text

Morphology and biochemical variables in rats’placentas with pregestational visceral obesity by Catherina Capote Guitian, Nínive Núñez López, Gladys González Aguilar, Amanda Llanes Tamayo, Maryanis Mosqueda Furones, Gipsis Suárez Román

“…<br /><strong>Methods:</strong> female Wistar rats were studied that received monosodium glutamate (4 mg/g of body weight) to induce obesity or 0.9% NaCl (controls) subcutaneously in the neonatal period. …”
Get full text

The histopathologic evaluation of local effects of ozone therapy on the healing of experimental calvarial defects of rats by Tolga Bayar, Ebru Deniz Karslı

“…Methods In our study, 24 male Wistar rats were divided into four groups: two control groups and two ozone-treated groups. …”
Get full text

Benidipine Protects Kidney through Inhibiting ROCK1 Activity and Reducing the Epithelium-Mesenchymal Transdifferentiation in Type 1 Diabetic Rats by Ganlin Wu, Meirong Xu, Kui Xu, Yilan Hu

“…We investigated the protective effect of benidipine, by testing the changes of the activity of Rho kinase and transdifferentiation of renal tubular epithelium cells in vivo. Wistar rats were randomly divided into two groups: normal (N) and diabetes. …”
Get full text

Median Preoptic Nucleus Mediates the Cardiovascular Recovery Induced by Hypertonic Saline in Hemorrhagic Shock by Nathalia Oda Amaral, Lara Marques Naves, Marcos Luiz Ferreira-Neto, André Henrique Freiria-Oliveira, Eduardo Colombari, Daniel Alves Rosa, Angela Adamski da Silva Reis, Danielle Ianzer, Carlos Henrique Xavier, Gustavo Rodrigues Pedrino

“…The recordings of mean arterial pressure (MAP) and renal vascular conductance (RVC) were carried out on male Wistar rats (250–300 g). Hemorrhagic shock was induced by blood withdrawal over 20 min until the MAP values of approximately 60 mmHg were attained. …”
Get full text

Clinical Evaluation of Faricimab in Real-World Diabetic Macular Edema in India- A Multicenter Observational Study by Chakraborty D, Das S, Maiti A, Sinha TK, Das A, Sheth J, Boral SK, Mondal S, Nandi K

“…Debdulal Chakraborty,1 Sudipta Das,2 Aniruddha Maiti,3 Tushar Kanti Sinha,1 Arnab Das,1 Jay Sheth,4 Subhendu Kumar Boral,1 Soumen Mondal,1 Krishnendu Nandi2 1Disha Eye Hospitals, Kolkata, India; 2Nethralayam Superspeciality Eye Care, Kolkata, India; 3Global Eye Hospitals, Kolkata, India; 4Department of Retina Services, Shantilal Shanghvi Eye Institute (SSEI), Mumbai, IndiaCorrespondence: Debdulal Chakraborty, Department of Vitreo-retinal Services, Disha Eye Hospitals, 88 Ghosh Para Road Barrackpore, Kolkata, West Bengal, 700120, India, Tel +91 33 6636 0000, Email devdc@rediffmail.comPurpose: To evaluate the efficacy of faricimab in real-world clinical settings in India for treating diabetic macular edema (DME) in treatment-naïve and recalcitrant eyes.Patients and Methods: This retrospective study involved 39 eyes (16 treatment-naive and 23 recalcitrant) treated with intravitreal faricimab at four centers in India. …”
Get full text

TINJAUAN SEMIOTIKA ATAS PEMAHAMAN HADITH DALAM KITAB FATH ALBARI KARYA IBN HAJAR ALASQALANI by Benny Afwadzi

“…The understanding model of the first hadith, in semiotic significance, indicates the existence of an understanding model with a signifier of denotation and connotation levels. …”
Get full text

Pengaruh Pemberian Ekstrak Rosella (Hibiscus sabdariffa Linn) Terhadap Kadar Malondialdehid dan Aktivitas Katalase Tikus yang Terpapar Karbon Tetraklorida by Zuraida , Eti Yerizel, Eliza Anas

“…Experimental research design with Post test Only Control Group Design. Samples of 24 male Wistar Strain rats were 2-3 months old. weighing 150-200 gr. …”
Get full text

Kombinasi K-Means dan Support Vector Machine (SVM) untuk Memprediksi Unsur Sara pada Tweet by Wiga Maulana Baihaqi, Muliasari Pinilih, Miftakhul Rohmah

“…Tulisan yang disampaikan melalui twitter dinamakan dengan tweets atau dalam bahasa indonesia lebih dikenal dengan kicau, tulisan yang dishare memiliki batas maksimum, tulisan tidak boleh lebih dari 140 karakter, karakter disini terdiri dari huruf, angka, dan simbol. …”
Get full text

Effects of Sildenafil and Vitamin E on Paraquat-Induced Pulmonary Fibrosis in Rats by Fouziyeh Siahpour, Hosein Sadeghi, Esmaeel Panahi kokhdan, Mohammad Khoshnoud

“…This study aimed to evaluate the effects of sildenafil and vitamin E on paraquat-induced pulmonary fibrosis. Male Wistar rats were used in animal studies. Paraquat was administered orally (R1-1) at a single dose of 40 mg/kg to induce lung fibrosis. …”
Get full text

The Cytokine and Bone Protein Expression by Ellagic Acid-Hydroxyapatite in Bone Remodelling Model by Dyah Noviana Primasari, Intan Nirwana, Hendrik Setia Budi, Agung Satria Wardhana, Annisa Fitria Sari, Novita Novita, Andika Putri Setyawan, Meircurius Dwi Condro Surboyo, Khairul Anuar Shariff

“…This study aimed to determine the effects of combining ellagic acid and hydroxyapatite in bone marker remodelling by analysing the expression of tumour necrosis factor-α (TNF-α), interleukin 10 (IL-10), bone morphogenetic 4 protein (BMP-4), and osteopontin (OPN). Methods. Thirty Wistar rats were used in the study. A defect was created in each animal’s femur using a low-speed diamond bur. …”
Get full text

Evaluation of antidiabetic potential, cardio, pancreatic, nephroprotective effect, and herb-herb-drug interaction of Madhukiran formulations in T2 diabetic rats by Vrushabh S. Kondalkar, Pranali P. Polshettiwar, Ganesh B. Choudhari, Anil T. Pawar, Vishnu P. Choudhari

“…Experimental procedure: Wistar rats were given a single intraperitoneal injection of STZ fifteen minutes after receiving an injection of NA, which caused diabetes. …”
Get full text

In Utero Nutritional Manipulation Provokes Dysregulated Adipocytokines Production in F1 Offspring in Rats by Mervat Y. Hanafi, Mohamed I. Saad, Taha M. Abdelkhalek, Moustafa M. Saleh, Maher A. Kamel

“…Materials and Methods. Wistar rats were allocated in groups: F1 offspring of control mothers under control diet (CF1-CD) and under high-fat diet (CF1-HCD), F1 offspring of obese mothers under CD (OF1-CD) and under HCD (OF1-HCD), and F1 offspring of malnourished mothers under CD (MF1-CD) and under HCD (MF1-HCD). …”
Get full text

Deferasirox improved iron homeostasis and hematopoiesis in ovariectomized rats with iron accumulation by Niloofar Honari, Mahtab Sayadi, Seyed Mehdi Sajjadi, Somayeh Solhjoo, Gholamreza Anani Sarab

“…This study aims to investigate the effects of Deferasirox on iron homeostasis and hematopoiesis in ovariectomized rats with iron accumulation. Sixty-four female Wistar rats were divided into eight groups and underwent ovariectomy surgery to simulate menopause. …”
Get full text

Luteolin ameliorates rat model of metabolic syndrome-induced cardiac injury by apoptosis suppression and autophagy promotion via NR4A2/p53 regulation by Xiyan Dai, Bo Liang, Yaolin Sun

“…Methods Forty male albino Wistar rats were divided into 5 groups randomly as controls, MetS, and MetS animals treated with luteolin (25, 50, 100 mg/kg ip). …”
Get full text

Larval Cytotoxic and Subacute Toxicity of Gardenia ternifolia, Rourea coccinea, and Cassytha filiformis Used in Traditional Medicine of Benin (West Africa) by E. Agbodjento, J. R. Klotoé, T. I. Sacramento, T. V. Dougnon, E. Déguenon, J. Agbankpé, K. Fabiyi, P. Assogba, M.-P. Hounkanrin, R. Akotegnon, T. J. Dougnon, J.-M. Atègbo

“…The subacute toxicity of these plants was evaluated in male Wistar albino rats at three different doses (200, 400, and 800 mg/kg) according to the OECD 407 guidelines. …”
Get full text

Different Dietary Proportions of Fish Oil Regulate Inflammatory Factors but Do Not Change Intestinal Tight Junction ZO-1 Expression in Ethanol-Fed Rats by Yi-Wen Chien, Hsiang-Chi Peng, Ya-Ling Chen, Man-Hui Pai, Hsiao-Yun Wang, Hsiao-Li Chuang, Suh-Ching Yang

“…Sixty male Wistar rats were fed a control or an ethanol-containing diet in groups C or E. …”
Get full text

Habit of elongate amphibole particles as a predictor of mesothelial carcinogenicity by Andrey A. Korchevskiy, Ann G. Wylie

“…It was demonstrated that modeled mesothelioma potency correlates with relative potency for pleural instillation in Wistar rats, and correlates inversely with membranolytic toxicity index HC50. …”
Get full text