Activation of TLR4-Mediated NF𝜅B Signaling in Hemorrhagic Brain in Rats by Weiyu Teng, Lishu Wang, Weishuang Xue, Chao Guan

“…The present study was to evaluate the temporal profile of the expression of TLR4 and the activation of TLR4-mediated NF𝜅B signaling in brain tissues of Wistar rats after ICH. TLR4 mRNA and protein, the phosphorylation of inhibitors of kappa B (p-I𝜅B𝛼), and the activity of NF𝜅B were examined in hemorrhagic cerebral tissue by Rt-PCR, Western blots, immunohistochemistry staining, and EMSA. …”
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Cardiopulmonary Profile in Streptozotocin-Induced Type 1 Diabetic Rats during Systemic Endotoxemia by Ching-Hsia Hung, Che-Ning Chang, Yu-Wen Chen, Yu-Chung Chen, Jann-Inn Tzeng, Jhi-Joung Wang

“…Thirty-two adult male Wistar rats were randomly assigned to a control group or to a group treated with streptozotocin (STZ) to create an animal model of type 1 diabetes. …”
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The KAB MIRROR by Felix, Mwesige

“…We pledge to develop The Kab Mirror to its desired standards. We wish you the best.…”
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Role of Mas Receptor Antagonist A799 in Renal Blood Flow Response to Ang 1-7 after Bradykinin Administration in Ovariectomized Estradiol-Treated Rats by Aghdas Dehghani, Shadan Saberi, Mehdi Nematbakhsh

“…Methods. Ovariectomized Wistar rats received estradiol (OVE) or vehicle (OV) for two weeks. …”
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Evaluation of antihyperlipidemic effect of rosemary oil in streptozotocin-induced diabetic rats by Deniz Uluisik, Ercan Keskin

“…<p> <b>Materials and Methods:</b> In this study, thirty-two adult male Wistar Albino rats were used. Working groups were consisted as follows: control group (C, n=6), rosemary group (R, n=6), diabetes group (STZ, n=10) and diabetes+rosemary group (STZ+R, n=10). …”
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Histopathologic Evaluation of Nonalcoholic Fatty Liver Disease in Hypothyroidism-Induced Rats by Şule Demir, Mustafa Ünübol, Serap Ünübol Aypak, Emrah İpek, Serdar Aktaş, Gamze Sevri Ekren, Murat Yılmaz, Recai Tunca, Engin Güney

“…Therefore, our study aims to evaluate NAFLD, from the histopathologic perspective, in hypothyroidism-induced rats. Wistar rats were divided into 2 groups: the experimental group consumed water containing methimazole 0.025% (MMI, Sigma, USA) for 12 weeks and the control group consumed tap water. …”
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Effects of gestational and lactational exposure to ethanol on body and bone growth of rat offspring by Natalia Viana Tamiasso, Fabiana Rocha Araújo, Natália de Melo Ocarino, Amanda Maria Sena Reis, Athelson Stefanon Bittencourt, Rogéria Serakides

“…Objective: To evaluate the effects of maternal ethanol consumption during pregnancy (prenatal) as well as during pregnancy and lactation (pre- and post-natal). Methods: 12 Wistar rats were divided into ethanol and control groups. …”
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The Effects of Vitamin D on Gentamicin-Induced Acute Kidney Injury in Experimental Rat Model by Ender Hur, Alev Garip, Asuman Camyar, Sibel Ilgun, Melih Ozisik, Sena Tuna, Murat Olukman, Zehra Narli Ozdemir, Eser Yildirim Sozmen, Sait Sen, Fehmi Akcicek, Soner Duman

“…Methods. Thirty nonuremic Wistar albino rats were divided into 3 groups: Control group, 1 mL saline intramuscular (im) daily; Genta group, gentamicin 100 mg/kg/day (im); Genta + vitamin D, gentamicin 100 mg/kg/day (im) in addition to 1α, 25 (OH)2D3 0.4 mcg/kg/day subcutaneously for 8 days. …”
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Antifibrotic Effect of Combination of Nilotinib and Stem Cell-Conditioned Media on CCl4-Induced Liver Fibrosis by Gamal Shiha, Ahmed Nabil, Ahmed Lotfy, Reham Soliman, Ayman A. Hassan, Islam S. Ali, Doaa F. Gad, Faten Zahran

“…This study was carried out to examine the antifibrotic effect of Nilotinib and stem cell exosomes on CCl4-induced liver fibrosis in rats. Male Wistar rats were injected intraperitoneally with CCl4 twice a week for 9 weeks and given daily treatments of Nilotinib (20 mg/kg), stem cell exosomes (0.5 ml/rat), and the combination treatment of Nilotinib and stem cell exosomes during the last 5 weeks of CCl4 intoxication. …”
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Sevoflurane Preconditioning plus Postconditioning Decreases Inflammatory Response with Hemodynamic Recovery in Experimental Liver Ischemia Reperfusion by Estela Regina Ramos Figueira, Joel Avancini Rocha-Filho, Cinthia Lanchotte, Ana Maria Mendonça Coelho, Mauro Nakatani, Eduardo Ryoiti Tatebe, Jonathan Augusto Venceslau Lima, Camilla Oliveira Mendes, Bruno Camargo Rocha Paim de Araujo, Emilio Elias Abdo, Luiz Carneiro D’Albuquerque, Flavio Henrique Ferreira Galvão

“…Materials and Methods. Twenty Wistar rats were divided into four groups: sham group, control ischemia group (partial warm liver ischemia for 45 min followed by 4 h of reperfusion), SPC group (administration of sevoflurane 2.5% for 15 min with 5 min of washout before liver IR), and SPPoC group (administration of sevoflurane 2.5% for 15 min before ischemia and 20 min during reperfusion). …”
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Enhanced bioavailability of Quercetin-loaded niosomal in situ gel for the management of Parkinson’s disease by Abhishek A. Revankar, Archana S. Patil, Reshma Karishetti, Krutuja R. Chougule, Priyanka Patil, Abhijit Salokhe

“…This study investigates the formulation of quercetin, a natural bioflavonoid with potent antioxidant and anti-inflammatory properties, as niosomes for intranasal delivery to enhance its bioavailability and therapeutic potential for PD.MethodsThe niosomal formulation was optimized for critical parameters including particle size, entrapment efficiency, and zeta potential. Male Wistar rats were utilized to assess the effects of quercetin-loaded niosomes on motor function, dopaminergic neuron protection, and oxidative stress alleviation.ResultsThe optimized niosomal formulation exhibited a particle size of 195 nm, a polydispersity index (PDI) of 0.29, a zeta potential (ZP) of −30.63 mV, and an entrapment efficiency (EE) of 82.77%. …”
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The Change of Left Ventricular Function in Rats with Subclinical Hypothyroid and the Effects of Thyroxine Replacement by Xuedi Chen, Cuixia Gao, Ningning Gong, Yu Wang, Limin Tian

“…Methods. Sixty-five male Wistar rats were randomly divided into five groups: control group; sHT A, B, and C group; and sHT + T4 group. …”
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Cardiovascular Protective Effect of Garcinia dulcis Flower Acetone Extract in 2-Kidney-1-Clip Hypertensive Rats by Nattaya Thongsepee, Pongsakorn Martviset, Wanwisa Himakhun, Pathanin Chantree, Phornphan Sornchuer, Kant Sangpairoj, Siriphun Hiranyachattada

“…The objective of this study was to examine the cardiovascular protective effect of GD flower acetone extract in 2-kidney-1-clip (2K1C) hypertensive rats. Male Wistar rats underwent 2K1C or sham operation (SO) and were housed for 4 weeks. …”
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The Ginkgo biloba Extract Reverses the Renal Effects of Titanium Dioxide Nanoparticles in Adult Male Rats by Carlos Enrique Escárcega-González, Irma Guadalupe Reynoso-Andeola, Fernando Jaramillo-Juárez, Haydée Martínez-Ruvalcaba, Francisco A. Posadas del Rio

“…It contains 27% of the polyphenols isorhamnetin, kaempferol, and quercetin, as antioxidants. We used male adult Wistar rats (200–300 g), divided into four groups: control group (treated with 5.0 mg/kg of sodium chloride, intravenous), titanium dioxide nanoparticles (TiO2-NPs) group (5.0 mg/kg, intravenous), GbE group (10 mg/kg, intraperitoneal), and GbE + TiO2-NPs group (treated 24 h before with 10 mg/kg of GbE, intraperitoneal), followed, 24 h later, by 5.0 mg/kg of TiO2-NPs intravenously. …”
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Pengaruh Bone Marrow Mesenchymal Stem Cells Terhadap Sekresi VEGF pada Penyembuhan Luka Bakar Tikus by Gusti Revilla

“…This research was an experimental research with design the post-test only control, using 12 Wistar rats, divided into 2 groups: control (PBS), treatment (BM-MSCs), stem-cells subcutaneously administered dose of 2 x 106 cells / ml. …”
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Investigation of PACAP Fragments and Related Peptides in Chronic Retinal Hypoperfusion by Dora Werling, Dora Reglodi, Peter Kiss, Gabor Toth, Krisztina Szabadfi, Andrea Tamas, Zsolt Biro, Tamas Atlasz

“…The aim of the present study was to investigate the potential retinoprotective effects of different PACAP fragments (PACAP 4-13, 4-22, 6-10, 6-15, 11-15, and 20-31) and related peptides (secretin, glucagon) in BCCAO-induced ischemic retinopathy. Wistar rats (3-4 months old) were used in the experiment. …”
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Abnormal Expression of Connexin43 in Cardiac Injury Induced by S-Band and X-Band Microwave Exposure in Rats by Yue Yin, Xinping Xu, Yabing Gao, Juan Wang, Binwei Yao, Li Zhao, Haoyu Wang, Hui Wang, Ji Dong, Jing Zhang, Ruiyun Peng

“…We used S- and X-band radiation sources with the average power density of 5 and 10 mW/cm2 to expose Wistar rats to single or composite exposure. At the 6th hour, on the 7th, 14th, and 28th days after exposure, ECG was used to detect the electrical conduction of the heart, and the myocardial enzyme was measured by the automatic biochemical analyzer. …”
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Hypolipidemic Effect of Chloroform Extract of Lagenaria siceraria: Potential Inhibitory Activity of Phytochemicals Targeting the HMG-CoA Reductase Revealed by Molecular Docking and... by Qudsia Kanwal, Mahmood Ahmed, Atiq Ur-Rehman, Aneela Anwar, Samiah Shahid, Atif Shahzad, Attaullah Shah Bukhari, Muhammad Ahmad, Numan Yousaf, Muhammad Muddassar

“…This study aimed to investigate the phytochemicals and in vivo hypolipidemic effect of chloroform extract of Lagenaria siceraria in Triton X-100 (100 mg/kg body weight) induced hyperlipidemic Wistar rats. The phytochemical characterization and estimation were performed on the base of the GC-MS approach. …”
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The Effect of Antivascular Endothelial Growth Factor on the Development of Adhesion Formation in Laparotomized Rats: Experimental Study by Murat Basbug, Nurullah Bulbuller, Cemalettin Camci, Refik Ayten, Erhan Aygen, Ibrahim Hanifi Ozercan, Zulfu Arikanoglu, Sami Akbulut

“…Methodology. Thirty female Wistar albino rats (200–224 g) were divided into three groups. …”
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The impact of absorbable hemostatic agents on wound healing in an experimental penile fracture rat model by Mehmet Ezer, Engin Doğantekin, Muzaffer Çaydere, Aykut Koç, Çağrı Öktem, Sema Hücümenoğlu

“…Materials and methods A total of 32 Wistar albino rats were divided into four groups: Control (C), Primary Suturing (PS), ORC, and Gelatin Sponge (GS). …”
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