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821
Immune and Inflammatory Responses of the Intestinal Mucosa following Extended Liver Radiofrequency Ablation
Published 2017-01-01“…The aim of the present project was to study the immune and inflammatory responses of the intestinal mucosa after extended RFA of the liver. Methods. Twelve Wistar rats were either subjected to RFA of the left lateral hepatic lobe (approximately 30% of the liver mass) after midline laparotomy (group RFA, n=6) or sham operation (group Sham, n=6). …”
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822
Increased N-Ethylmaleimide-Sensitive Factor Expression in Amygdala and Perirhinal Cortex during Habituation of Taste Neophobia
Published 2016-01-01“…Twenty-one naïve male Wistar rats were exposed to a saccharin solution (0.4%) during the first (novel), the second (Familiar I), and the sixth presentation (Familiar II). …”
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823
Effects of Thalidomide on the Expression of Adhesion Molecules in Rat Liver Cirrhosis
Published 2006-01-01“…The cirrhosis was induced in Wistar rats by intraperitoneal injection of <mml:math> <mml:mrow> <mml:msub> <mml:mrow> <mml:mtext>CCl</mml:mtext> </mml:mrow> <mml:mn>4</mml:mn> </mml:msub> </mml:mrow> </mml:math>, and thalidomide (10 mg/kg/day or 100 mg/kg/day) was given by intragastric administration for 8 weeks. …”
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824
Deoxycholic Acid as a Modifier of the Permeation of Gliclazide through the Blood Brain Barrier of a Rat
Published 2013-01-01“…Accordingly, the aim of this study is to investigate whether the bile acid (deoxycholic acid) can change the permeation of gliclazide, through the blood brain barrier of a rat model type-1 diabetes. Twenty-four male Wistar rats were randomly allocated to four groups, of which, two were given alloxan intraperitoneally (100 mg/kg) to induce diabetes. …”
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825
The Combination Therapy with Zoledronic Acid and Propranolol Improves the Trabecular Microarchitecture and Mechanical Property in an Rat Model of Postmenopausal Osteoporosis
Published 2014-01-01“…We conducted the present study to investigate the therapeutic effects of propranolol (PRO), alone and in combination with the antiresorptive agent ZOL, in a rat model of postmenopausal osteoporosis. Female Wistar rats were OVX or sham-operated at 3 months of age. …”
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826
Cerebral Epiphyseal Proteins and Melatonin Modulate the Hepatic and Renal Antioxidant Defense of Rats
Published 2011-01-01“…In view of the therapeutic potential of these proteins, the present experiment was conducted to investigate the effect of buffalo epiphyseal proteins (BEP, at 100 μg/kg BW, i.p.) and melatonin (MEL, at 10 mg/kg BW, i.p) on changes in hepatic and renal antioxidant enzymes of adult female Wistar rats. Buffalo epiphyseal proteins significantly (P<.05) increased hepatic lipid peroxidation (LPO), superoxide dismutase (SOD), glutathione reductase (GR), glutathione peroxidase (GPx), reduced glutathione (GSH), and renal LPO, catalase (CAT), GR, GSH, GPx levels as compared to control animals. …”
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827
In Vivo Assessment of Healing Potential of Ointments Containing Bee Products, Vegetal Extracts, and Polymers on Skin Lesions
Published 2025-01-01“…<b>Methods</b>: In order to investigate the therapeutic properties of the ointments, experimental in vivo injury models (linear incision, circular excision, and thermal burns) were performed on laboratory animals, namely Wistar rats. The treatment was applied topically, once a day, for 21 days. …”
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828
The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
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829
An Evaluation of the Biocompatibility and Chemical Properties of Two Bioceramic Root Canal Sealers in a Sealer Extrusion Model of Rat Molars
Published 2025-01-01“…This study assessed the biocompatibility and chemical properties of two bioceramic root canal sealers, EndoSequence BC Sealer (EBC) and Nishika Canal Sealer BG (NBG), using a sealer extrusion model. Eight-week-old male Wistar rats were used. The mesial root canals of the upper first molars were pulpectomized and overfilled with EBC, NBG, or, as reference, epoxy resin-based AH Plus (AHP). …”
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830
Chronic Hyperglycemia Modulates Rat Osteoporotic Cortical Bone Microarchitecture into Less Fragile Structures
Published 2017-01-01“…In this study, the effect of chronic hyperglycemia in bone turnover, morphology, and biomechanics was evaluated in female Wistar rats in the presence/absence of estrogens (ovariectomy). …”
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831
Elevation of Glucose 6-Phosphate Dehydrogenase Activity Induced by Amplified Insulin Response in Low Glutathione Levels in Rat Liver
Published 2016-01-01“…Weanling male Wistar rats were fed on a 10% soybean protein isolate (SPI) diet for 3 weeks with or without supplementing 0.3% sulfur-containing amino acids (SAA; methionine or cystine) to examine relationship between glutathione (GSH) levels and activities of NADPH-producing enzymes, glucose 6-phosphate dehydrogenase (G6PD) and malic enzyme (ME), in the liver. …”
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832
Azithromycin Prevents Pregnancy Loss: Reducing the Level of Tumor Necrosis Factor-Alpha and Raising the Level of Interleukin-10 in Rats
Published 2013-01-01“…Thirty-six pregnant female Wistar rats were divided into 4 equal groups as follows: control group, where 0.3 mL of normal saline solution was administered intravenously on day 10 of pregnancy; azithromycin group, where azithromycin was administered orally at 350 mg kg−1 day on days 9, 10, and 11 of pregnancy; lipopolysaccharide group, where LPS was administered intravenously via the tail vein at 160 μg kg−1 on day 10 of pregnancy; and the azithromycin + LPS group, where azithromycin was administered orally at 350 mg kg−1 day on days 9, 10, and 11 of pregnancy and LPS was administered intravenously at 160 μg kg−1 on day 10 of pregnancy. …”
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833
HMGB1 Box A gene therapy to alleviate bleomycin-induced pulmonary fibrosis in rats
Published 2025-01-01“…In a bleomycin-induced pulmonary fibrosis model in the male Wistar rats, Student’s t-test and one-way ANOVA were used to compare groups of samples. …”
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834
Preclinical Evidences for an Antimanic Effect of Carvedilol
Published 2015-01-01“…Thus, we hypothesized that CVD would prevent and/or reverse mania-like behavioral and neurochemical alterations induced by lisdexamfetamine dimesylate (LDX). To do this, male Wistar rats were submitted to two different protocols, namely, prevention and reversal. …”
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835
Inhibitory Effect of NMDA Receptors in the Ventral Tegmental Area on Hormonal and Eating Behavior Responses to Stress in Rats
Published 2014-01-01“…The effects of intraventral tegmental area (I-VTA) memantine on the plasma corticosterone and eating parameters disturbance induced by acute stress were investigated. Methods. Male Wistar rats (W: 250–300 g) were divided into control and experiential groups, each of which received memantine either intra-VTA or peripherally. …”
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836
The 1886 Yoruba Peace Treaty and Imperative Lessons of Yoruba National Unity
Published 2021-12-01“…I salute all our guests, friends, and well-wishers here gathered. Ladies and Gentlemen: In the thousands of years of the pre-20th century history of the Yoruba nation, the Yoruba Peace Treaty of September 23 1886 is a unique document of incalculable importance. …”
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837
The use of drones and Artificial Intelligence for dugong sighting detection in a limited resource scenario
Published 2025-01-01“…This study aims to recount our experience conducting a combination of drone and AI-assisted detection (WISDAM) in a scenario with limited resources to detect dugongs. …”
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838
Protective effect of Panax ginseng extract on cisplatin-induced AKI via downregulating cell death associated genes
Published 2025-01-01“…Abstract This study is designed to assess the effect of root extract of P. ginseng on kidney tissue injury attributed to cisplatin and its molecular mechanism involved in this process in the AKI rat model. Twenty-four male Wistar rats were randomly allocated into 4 experimental groups including: the control group, the cisplatin group, the extract 100 mg/kg group, and the extract 200 mg/kg group. …”
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839
Alteration of Loperamide-Induced Prostate Relaxation in High-Fat Diet-Fed Rats
Published 2014-01-01“…Materials and Methods. Adult male Wistar rats were divided into 2 groups: (1) control rats fed with normal chow and (2) rats fed with HFD for 6 months. …”
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840
Recovery from Lesion-Associated Learning Deficits by Fetal Amygdala Transplants
Published 2002-01-01“…In two groups of adult Wistar rats, sham operation or bilateral lesions of the CeA were produced electrolytically (2mA for 8 sec). …”
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