Recombinant expression systems for production of stabilised virus-like particles as next-generation polio vaccines by Lee Sherry, Mohammad W. Bahar, Claudine Porta, Helen Fox, Keith Grehan, Veronica Nasta, Helen M. E. Duyvesteyn, Luigi De Colibus, Johanna Marsian, Inga Murdoch, Daniel Ponndorf, Seong-Ryong Kim, Sachin Shah, Sarah Carlyle, Jessica J. Swanson, Sue Matthews, Clare Nicol, George P. Lomonossoff, Andrew J. Macadam, Elizabeth E. Fry, David I. Stuart, Nicola J. Stonehouse, David J. Rowlands

“…We compare the antigenicity, thermostability and immunogenicity of these stabilized VLPs against the current inactivated polio vaccine, demonstrating equivalent or superior immunogenicity in female Wistar rats. Structural analyses of these recombinant VLPs provide a rational understanding of the stabilizing mutations and the role of potential excipients. …”
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A finite element method for growth in biological development by Cornel M. Murea, H. G. E. Hentschel

“…We describe finite element simulations of limb growth based on Stokes flow models witha nonzero divergence representing growth due to nutrients in the early stages of limb bud development.We introduce a ''tissue pressure'' whose spatial derivatives yield the growth velocity in the limband our explicit time advancing algorithm for such tissue flows is described in detail.The limb boundary is approached by spline functions to compute the curvature andthe unit outward normal vector. …”
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Incidence and Mechanisms of Coronary Perforations during Rotational Atherectomy in Modern Practice by Yen-Hsiang Wang, Wei-Jhong Chen, Yu-Wei Chen, Chih-Hung Lai, Chieh-Shou Su, Wei-Chun Chang, Chi-Yen Wang, Kae-Woei Liang, Tsun-Jui Liu, Wen-Lieng Lee

“…Knowing why CPs occur in RA should help operators avert such mishaps. Method. Patients who received coronary RA from April 2010 to December 2019 with keywords related to perforations were retrieved from database. …”
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Cucumeropsis mannii seed oil shields against cyclophosphamide-induced hepatorenal toxicity by modulating redox imbalance and iNOS/IL-β1 signalling in rats by Amaka Cecilia Agbara, Ejike Daniel Eze, Christian Emeka Offor, Adam Moyosore Afodun, Ezebuilo Ugbala Ekpono, Peter Chinedu Agu, Chinyere Aloke, Nkeiru Nwaamaka Ezeani, Emmanuel Orire Ikuomola, Ekom Monday Etukudo, Ilemobayo Victor Fasogbon, Angela Mumbua Musyoka, Patrick Maduabuchi Aja

“…We randomly assigned thirty-six (36) male Wistar rats into six groups of six rats each. Groups A and B served as normal and negative controls, respectively. …”
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Saussurea gossypiphora extracts reduce inflammation by reversing inflammatory cytokine levels in in-vitro and in-vivo by Kalyani Jatoth, Pawan Kumar Anoor, Ramesh Kande, Sandeepta Burgula

“…Carrageenan was used to assess the anti-Inflammatory activity in the right hind paw edema of male Wistar rats. Effect of MESGD on inflammasome pathway was studied by performing ELISA for IL-1β, TNF-α and confirmed by immunoblotting for NLRP3 and Caspase 1 in THP1 cells. …”
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Xiaohua Funing decoction ameliorates non-alcoholic fatty liver disease by modulating the gut microbiota and bile acids by Jindong Zhao, Jindong Zhao, Yan Li

“…The effects of obeticholic acid (OCA) and XFD on Mod rats were subsequently evaluated. Wistar rats in the control (Con) group were fed a standard diet. …”
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Optimal and suboptimal protocols for a mathematical model for tumor anti-angiogenesis in combination with chemotherapy by Urszula Ledzewicz, Helmut Maurer, Heinz Schättler

“…For oneunderlying mathematical model, optimal and suboptimal solutions aregiven for four versions of this problem: the case when onlyanti-angiogenic agents are administered, combination treatment witha cytotoxic agent, and when a standard linear pharmacokineticequation for the anti-angiogenic agent is added to each of thesemodels. …”
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BEHAVIOR OF RAT NEONATES WITH INHERITED STRESS-INDUCED ARTERIAL HYPERTENSION by I. O. Meshkov, T. A. Alekhina, T. A. Moreva

“…The strains were: rats with inherited stress-induced arterial hypertension (ISIAH) and Wistar Albino Glaxo (WAG) rats as control. Different dynamics of weight gain and vibrissae growth were shown. …”
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Increased NOX-dependent ROS production and proportionally enhanced antioxidant response in white adipose tissue of male rats by Jessica de Freitas Nascimento, Keciany Alves de Oliveira, Paula Alexandre de Freitas, Júlia de Araújo Marques Falci, Renata Prado Vasconcelos, Saulo Chaves Magalhães, Talita Mendes Farias, Maria Isabel Cardoso Alonso-Vale, Adriano Cesar Carneiro Loureiro, Denise Pires de Carvalho, Rodrigo Soares Fortunato, Ariclécio Cunha de Oliveira

“…ABSTRACT Objective: This study aimed to investigate the redox balance in subcutaneous and retroperitoneal fat pads of male and female Wistar rats. Materials and methods: The study analyzed the activity and gene expression of the antioxidant enzymes superoxide dismutase, catalase, and glutathione peroxidase, along with the production of NADPH oxidases dependent on H2O2 and gene expression of NOX1, NOX2, and NOX4. …”
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In vivo evaluation biological of protein quality of hamburgers containing fibers by Tiffany Prokopp Hautrive, Ângela Souza Rodrigues, Karine Ines Bolson Moro, Gilberti Helena Hübscher, Ernesto Hashime Kubota

“…This study aimed to evaluate the protein quality of hamburgers made with chitosan and golden flaxseed meal defatted through biological response in rats. Male Wistar rats were fed for 28 days with the following experimental treatments: protein diet and diets diet with casein-tests where casein was replaced by traditional burger meal (HT), burger meal with chitosan (HQ) and burger meal with golden defatted flaxseed meal (HLD). …”
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Molecular networking-assisted flavonoid profile of Gypsophila glomerata extract in relation to its protective effects on carbon tetrachloride-induced hepatorenal damage in rats by Dimitrova Bojana, Vitanska Rumyana, Gevrenova Reneta, Zheleva-Dimitrova Dimitrina, Balabanova Vessela, Stoev Stoycho

“…Ex Adams (Caryophyllaceae) (EGG) and to assess its protective potential on carbon tetrachloride (CCl4)-induced liver and kidney damage in male Wistar rats. Twenty-two flavonoid C-, O- and C,O--glycosides in EGG were annotated by mass spectrometry--based molecular networking; nine of them are reported in this species for the first time. …”
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Protective effects of blueberry anthocyanin extracts on hippocampal neuron damage induced by extremely low-frequency electromagnetic field by Xiyun Sun, Zihan Xu, Yuehua Wang, Ning Liu

“…The protective effects of blueberry anthocyanin extracts against damage induced by extremely low-frequency electromagnetic field (ELF-EMF) were investigated in a rat model. Wistar rats were exposed to ELF-EMF with or without the administration of blueberry anthocyanin extracts (50, 100, and 200 mg/kg per day intragastrically once a day) for 30 days. …”
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Chronic Sleep Disturbance Impairs Glucose Homeostasis in Rats by R. Paulien Barf, Peter Meerlo, Anton J. W. Scheurink

“…To assess a possible causal relationship, we examined the effects of experimental sleep disturbance on glucose regulation in Wistar rats under controlled laboratory conditions. …”
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Antioxidant Vitamins as Oxidative Stress Markers in Rat Plasma After Physical Exercise - a Short Report by Wawrzyniak Agata, Hamułka Jadwiga, Drywień Małgorzata, Górnicka Magdalena, Pierzynowska Jolanta, Wojtaś Malwina, Gajewska Małgorzata, Frąckiewicz Joanna, Gronowska-Senger Anna

“…The aim of the study was to verify the hypothesis that β-carotene, vitamin E, vitamin C administered individually or in combination may differently modify their levels in blood plasma being also markers of the oxidative stress. Male Wistar rats were supplemented antioxidants per os (α-to-copherol - 2 mg/d, ascorbic acid - 12 mg/d, β-carotene - 1 mg/d), both individually or in combination of 2 or 3, for 14 days. …”
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Garlic and Onion Attenuates Vascular Inflammation and Oxidative Stress in Fructose-Fed Rats by Marcela Alejandra Vazquez-Prieto, Cecilia Rodriguez Lanzi, Carina Lembo, Claudio Rómulo Galmarini, Roberto Miguel Miatello

“…This study evaluates the antioxidant and the anti-inflammatory properties of garlic (G) and onion (O) in fructose-fed rats (FFR). Thirty-day-old male Wistar rats were assigned to control (C), F (10% fructose in drinking water), F+T (tempol 1 mM as control antioxidant), F+G, and F+O. …”
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Histopathological, Histomorphometrical, and Radiographical Evaluation of Injectable Glass-Ceramic-Chitosan Nanocomposite in Bone Reconstruction of Rat by Maryam Seyedmajidi, Seyedmahmood Rabiee, Sina Haghanifar, Seyedkamal Seyedmajidi, Seyed Gholam ali Jorsaraei, Homayoun Alaghehmand, Naghmeh Jamaatlu, Ali Bijani

“…Thirty-two 6–8-week-old male Wistar rats were chosen. One hole on each right and left tibia was made. …”
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Evaluation of antioxidant and anti-hypercholesterolemic potential of Vitis vinifera leaves by Sushma Devi, Randhir Singh

“…In the present study, we evaluated anti-hypercholesterolemic potential of Vitis vinifera red leaves extract in experimental wistar male rats. Material and methods: Qualitative and quantitative phytochemical screening of vitis vinifera methanolic extract (VVME) and vitis vinifera aqueous extract aqueous (VVAE) extract was carried out to identify the phytoconstituents. …”
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Islet Stellate Cells Isolated from Fibrotic Islet of Goto-Kakizaki Rats Affect Biological Behavior of Beta-Cell by Feng-Fei Li, Bi-Jun Chen, Wei Li, Ling Li, Min Zha, S. Zhou, M. G. Bachem, Zi-Lin Sun

“…We previously isolated islet stellate cells (ISCs) from healthy Wistar rat islets. In the present study, we isolated “already primed by diabetic environment” ISCs from islets of Goto-Kakizaki rats, determined the gene profile of these cells, and assessed the effects of these ISCs on beta-cell function and survival. …”
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Influence of Chronic Alcohol Use on Osteoblastic Differentiation of Bone Marrow Cells, Bone Properties, and Hepatic and Renal Morphology of Rats by Michelle Cardoso de Sousa, Mariana Raquel da Cruz Vegian, Matheus Alves Biserra, Bruno César Almeida Costa, Samira Esteves Afonso Camargo, Sigmar de Mello Rode, Carolina Judica Ramos, Luciane Dias de Oliveira, Luana Marotta Reis de Vasconcellos

“…The aim of this study was to evaluate the effects of chronic use of 20% alcohol on rats regarding osteoblastic differentiation, extrinsic and intrinsic properties of the tibia, and hepatic and renal morphology. Wistar rats were divided into three groups (n=9) in accordance with a 24-week diet. …”
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Diets Rich in Olive Oil, Palm Oil, or Lard Alter Mitochondrial Biogenesis and Mitochondrial Membrane Composition in Rat Liver by Youzan Ferdiand Djohan, Massara Camara-Cissé, Gilles Fouret, Béatrice Bonafos, Bernard Jover, Jean-Paul Cristol, Charles Coudray, Christine Feillet-Coudray, Eric Badia

“…This was an experimental study in male Wistar rats fed a diet containing 30% of each oil. …”
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