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19461
Identification of cuproptosis and ferroptosis-related subtypes and development of a prognostic signature in colon cancer.
Published 2025-01-01“…AZD8055_1059, Bortezomib_1191, Dihydrorotenone_1827, and MG-132_1862 were more sensitive in the high-risk group. Finally, we analyzed differential expression of model-related genes between tumor tissues and normal tissues, validated through real-time quantitative PCR and immunohistochemistry. …”
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19462
Comprehensive characterization of platelet function in dogs with hyperadrenocorticism
Published 2025-02-01“…Moreover, 2-MeSADP- and thrombin-induced thromboxane A2 (TxA2) generation was significantly inhibited in dogs with HAC compared to normal dogs, confirming the role of cortisol in TxA2 generation. Finally, thrombin-induced ERK and AKT phosphorylation were significantly inhibited in dogs with HAC. …”
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19463
Preoperative Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and CEA as the Potential Prognostic Biomarkers for Colorectal Cancer
Published 2022-01-01“…A total of 330 patients were finally included in the current study. The mean follow-up duration was 32.8 ± 19.1 months (range, 0.1–67.7). …”
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19464
Differential equations and recursive solutions for cosmological amplitudes
Published 2025-01-01“…Our method works for any graph: for a tree graph with n nodes, this system can be transformed into the canonical differential equations of size 4 n−1 equivalent to the graphic rules derived recently , and we also derive the system of differential equations for loop integrands e.g. of all-loop two-site graphs and one-loop n-gon graphs. Finally, we show how the differential equations truncate for the de Sitter (dS) case (in a way similar to differential equations for Feynman integrals truncate for integer dimensions), which immediately yields the complete symbol for the dS amplitude with interesting structures e.g. for n-site chains and n-gon cases.…”
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19465
A comprehensive pan-cancer analysis of RNF187 in human tumors
Published 2025-01-01“…The findings highlighted associations between RNF187 expression and Tumor Mutational Burden (TMB), Microsatellite Instability (MSI) and Homologous Recombination Deficiency (HRD) in specific tumors. Finally, RNF187 showed a significant positive association with five genes (ALKBH4, FAM134A, MLST8, SANP47 and TMEM9) across the majority of tumors. …”
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19466
Study on the Full‐Cycle Stress Evolution Law and Reasonable Size of Isolated Coal Pillar
Published 2025-01-01“…The results show that the vertical stress and maximum principal stress increase correspondingly with the decrease of the protective coal pillar size under both stages, and the minimum value of the minimum principal stress occurs on the 8 m protective coal pillar; The values of the principal stress ratio and the principal stress deflection angle do not differ greatly in the protection of the coal pillar, and the fluctuation of the values is mainly concentrated in the vicinity of the back‐mining roadway; The second invariant of bias stress (J2) is mainly concentrated in the protective coal pillar near the side of the extraction zone, when the size of the protective coal pillar is reduced to 10 m, the J2 on the side of the extraction zone and the J2 on the side of the roadway are connected, and the whole protective coal pillar is under the influence of J2, which is basically the same as the damage pattern of the plastic zone; Based on the formula of limit balance theory to calculate the elastic core width of different sizes of protective coal pillars, and combined with the results of numerical simulation analysis, it finally concluded that the reasonable size of the protective coal pillar of this isolated island working face is 15 m.…”
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19467
Time-Frequency Characteristics and the Influence Mechanism of the EMR from Coal with Different Joint Angles
Published 2021-01-01“…The duration of the EMR waveform, the dominant frequency of the EMR, and the peak number of the frequency spectrum of coal samples are on the rise. (2) As the joint angle increases, the samples’ failure mode changes from the stage fracture dominated by tension cracks to the rapid fracture with the coexistence of shear and tension cracks and finally to the burst fracture which produces a large number of fragments. …”
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19468
Multifunctional Proteins Bridge Mitosis with Motility and Cancer with Inflammation and Arthritis
Published 2010-01-01“…For these and other genes/proteins, we will highlight points of structural and functional intersection during cellular division and differentiation, as well as states associated with cancer, such as tumor-initiation and epithelial-to-mesenchymal transition (EMT). Finally, we will discuss the potential targeting of these proteins for improved therapeutic outcomes within these degenerative disorders. …”
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19469
Isotherms and Kinetic Studies of Copper Removal from Textile Wastewater and Aqueous Solution Using Powdered Banana Peel Waste as an Adsorbent in Batch Adsorption Systems
Published 2023-01-01“…The kinetics of copper (II) adsorption followed the second-order kinetic model better. Finally, these studies showed that banana peel bio-adsorbent is a potential adsorbent for heavy metal removal from synthetic and textile wastewater.…”
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19470
Two-Dimensional Electroosmotic Consolidation Theory of Nonlinear Soil Voltage Distribution Characteristics
Published 2019-01-01“…The derivation process considered both linear and nonlinear soil voltage distributions, wherein the anode was closed and the cathode was open. Finally, the analytical solution was analyzed and validated with model test cases in terms of the excess pore water pressure and average moisture content of the soil. …”
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19471
Biodiversity Change in Cultural Landscapes—The Rural Hotspot Hypothesis
Published 2025-01-01“…Spatiotemporal dimensions of backyard pressures involving material fluxes, species exchange and retention, alternation of site conditions, and local genetic adaptation are delineated for different backyard features, including building structures, gardens, lawns, and paved grounds. Finally, we propose a future research agenda to quantify effects and trends of rural hotspots and followed patterns of altered species dynamics. …”
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19472
Preventing and addressing youth vaping in British Columbia, Canada: Evidence from triangulation of a scoping review of vaping policy and qualitative interviews with school-aged you...
Published 2025-03-01“…The interviews, conducted in 2020 and 2021 in the Okanagan region of British Columbia, were analyzed using NVivo software through conventional content analysis, an inductive approach where two coders collaboratively identified categories and sub-categories from participant responses using a finalized codebook. Results: The policy review identified gaps in comprehensiveness, public accessibility, and enforcement, particularly at regional levels, where policies often lack comprehensiveness and fail to address vaping-specific challenges. …”
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19473
La poética del cuerpo en los relatos de Franz Kafka ‘En la colonia penitenciaria’ (1919) y ‘La metamorfosis’ (1915)
Published 2005-12-01“… La crisis de la modernidad hacia finales del siglo XIX en Centroeuropa da lugar a una literatura en los países de habla alemana que tematiza la asincronía entre la realidad socio-política y el proceso de modernización económica. …”
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19474
Commonality of Virulence-Promoting Function in Rhodococcus equi Virulence Associated Proteins (Vaps)
Published 2023-01-01“…There was a differential activity across these virulence-promoting Vaps with the most “acid-neutralising” activity found with VapN, then VapA and K, and finally VapB. These data suggest that VapA production, which is often found in equine infections, can be substituted by VapK and B (produced by plasmids often found in porcine species) or VapN (produced by plasmids often isolated in bovine and human samples). …”
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19475
Exploring the Mechanism of Antioxidant Action of Bitter Almond Based on Network Pharmacology and Molecular Docking Techniques
Published 2023-01-01“…The active ingredients of bitter almond were obtained through the traditional Chinese medicine systematic pharmacology database and analysis platform (TCMSP), and the main active ingredients were screened by bioavailability (OB) and drug-like properties (DL); the GeneCards database was used to search antioxidant-related disease targets through the traditional Chinese medicine systematic pharmacology database and analysis; building a “drug-disease-target” visual network map with Cytoscape 3.9.0 software; a protein interaction (PPI) network was constructed using STRING website and core targets were screened; GO function and KEGG pathway enrichment analysis were obtained using Metoscape. Finally, SailVina software was used to molecularly dock the major active ingredients and target proteins and visualize them using PyMOL software. …”
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19476
PEER TUTORING IN LEARNING A FOREIGN LANGUAGE AS A NON-MAJOR
Published 2017-04-01“…The undertaken experiment lasted for two years, showed that peer tutoring advantages in foreign language training consist in the following: firstly, such way of lessons allows teachers to avoid time-losing monotonous reading and translations of texts discouraging students; secondly, exchanging opinions, students study each other and gain skills of estimation of personal and others' work; thirdly, interacting in pairs or small groups, pupils are more active, than during the independent work or work organized by the teacher, they react to the arising educational situations; finally, such training considerably solves a problem of shortage of class periods on teaching the subject "Foreign language" as students manage to cope with much large scope of a training material as compared they manage to make during the traditional organization of an educational process.Practical significance. …”
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19477
Psychological Characteristics and Health Behavior for Juvenile Delinquency Groups
Published 2022-01-01“…By comparing the odds ratio (OR) of each question in the YPPQ test between the experimental group and the control group, it is found that the psychological characteristics of the experimental group are significantly affected by family, school, and even society. Finally, it proposes a “mixed hierarchical intervention model” for juvenile delinquency to intervene in health behaviors. …”
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19478
High-Performance Computational Early Warning Analysis of Agricultural Economy Relying on Binary Fuzzy Cluster Analysis Algorithm
Published 2021-01-01“…Its functional structure includes management business, innovation business, service business, production business, and operation business functions, in addition to the design of the collection and storage scheme based on Hadoop data warehouse, to achieve accurate matching of information of science and technology agricultural services in the whole agricultural industry chain. Finally, the implementation and maintenance of the cloud-based science and technology agricultural service information system are deployed, and the operational effects of its information system-related functions are demonstrated using prototype design. …”
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19479
Uplift Test and Design Method for Bearing Capacity of Isolated Spread Concrete Foundation Slab with Large Width-to-Height Ratio
Published 2018-01-01“…To obtain the suggested design method of uplift capacity for the foundation slab, effective width correction coefficient k and slope correction coefficient j were introduced to propose a design formula. Finally, the proposed design method was applied to a practical engineering, and the economic indicators obtained from the suggested design method were compared with that from the original design method. …”
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19480
Structural, Optical and Electrochromic Properties of Sol–Gel V2O5 Thin Films
Published 2003-01-01“…The absorbance of films colored at three different potentials is measured in the UV–VIS–PIR wavelength range, and this study shows that the changes in the optical absorption are consistent with the film color changes. Finally, the optical and electrochromic properties of the films prepared by this method are compared with those of our sputtered films already studied and with other works.…”
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