Fever, Myositis, and Paralysis: Is This Inflammatory Myopathy or Neuroinvasive Disease? by Aneeta R. Kiran, Richard A. Lau, Kim M. Wu, Andrew L. Wong, Philip J. Clements, Emil R. Heinze

“…Laboratory revealed a creatine kinase of 45,000 and a urinalysis with large blood but no red blood cells, suggesting rhabdomyolysis. …”
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Network pharmacology-based screening of the active ingredients and mechanisms of Cymbaria daurica against diabetes mellitus by Ruyu Shi, Dongxue Chen, Mingyue Ji, Baochang Zhou, Ziyan Zhang, Chunhong Zhang, Minhui Li

“…Then, a HepG2 cell insulin resistance model and a high-fat, high-glucose diet combined with a streptozotocin-induced T2DM rat model was established to assess the fasting glucose changes and lipid profile after C. daurica treatment, respectively. Finally, real-time PCR and western blotting were used to verify changes in key targets. …”
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Thymosin β4 Improves Differentiation and Vascularization of EHTs by Tilman Ziegler, Rabea Hinkel, Andrea Stöhr, Thomas Eschenhagen, Karl-Ludwig Laugwitz, Ferdinand le Noble, Robert David, Arne Hansen, Christian Kupatt

“…Furthermore, we demonstrated, in a zebrafish model of embryonic vascular development, that Tβ4 is crucial for the proper execution of lymphatic and angiogenic vessel sprouting. Finally, utilizing Tβ4-transduced EHTs generated from mice genetically engineered to label endothelial cells in vitro, we show that treatment with Tβ4 promotes vascularization and contractility in EHTs, highlighting Tβ4 as a growth factor improving the formation of cardiomyocytes from iPSC and enhancing the performance of EHTs generated from neonatal cardiomyocytes.…”
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lncRNA, miRNA, and mRNA of plasma and tumor-derived exosomes of cardiac myxoma-related ischaemic stroke by Lin Ma, Yu-Hua Liu, Chun Liu, Shu-Qi Wang, Jun Ma, Xiao-Qing Li, Min Ren, Ting-Ting Yang, Guang-Zhi Liu

“…Moreover, 5,533 lncRNAs, 1,331 known miRNAs, and 412 new miRNAs were identified. Finally, gene expression profiles and differentially expressed genes were analysed in 20 samples. …”
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Toward Intelligent Financial Advisors for Identifying Potential Clients: A Multitask Perspective by Qixiang Shao, Runlong Yu, Hongke Zhao, Chunli Liu, Mengyi Zhang, Hongmei Song, Qi Liu

“…In addition, we design a two-stage feature selection algorithm to select highly relevant user features efficiently and accurately from an incredibly huge number of user feature fields. Finally, we conduct extensive experiments on a real-world dataset provided by a famous fintech bank. …”
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High‐performance and flexible thermoelectric generator based on a robust carbon nanotube/BiSbTe foam by Myeong Hoon Jeong, Eun Jin Bae, Byoungwook Park, Jong‐Woon Ha, Mijeong Han, Young Hun Kang

“…The flexible TEG showed excellent stability and durability even after 10,000 bending cycles. Finally, we demonstrate the shapeability of the CNT/BST foam by fabricating a concave TEG with conformal contact on the surface of a cylindrical glass tube, which suggests its practical applicability as a thermal sensor.…”
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Genome Analysis of Rhodococcus Sp. DSSKP-R-001: A Highly Effective β-Estradiol-Degrading Bacterium by Hongyan Zhao, Kejian Tian, Qing Qiu, Yu Wang, Hongyan Zhang, Shuang Ma, Shenbao Jin, Hongliang Huo

“…The existence and expression of estradiol-degrading enzymes were verified by PCR and RTPCR. Finally, comparative genomics was used to compare multiple strains of Rhodococcus. …”
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FGF2 Attenuates Neural Cell Death via Suppressing Autophagy after Rat Mild Traumatic Brain Injury by Chonghui Tang, Yudong Shan, Yilan Hu, Zhanjian Fang, Yun Tong, Mengdan Chen, Xiaojie Wei, Xiaojun Fu, Xinlong Xu

“…FGF2 could also protect cells from various forms of death such as apoptosis or necrosis through inhibition of autophagy. Finally, autophagy activator rapamycin could abolish the protective effects of FGF2. …”
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Ekspresi Protein Sitoplasmik SOCs2 pada Adenokarsinoma Kolorektal: Studi Imunohistokimia by Nita Afriani Azmal, Shinta Ayu Intan, Tofrizal Tofrizal

“…They increase signaling pathways into cells via the Janus kinase pathway (JAK) - signal transducer and activator of transcription (STAT) -suppressor of cytokine signaling (SOCs) JAK-STAT. …”
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Computer-Aided Rapid Establishment of Fingerprint of Xiaojin Capsule by HPLC by Hui Jiang, Yuansheng Xiao, Xingya Xue, Hongli Jin, Yang Xiang, Yanfang Liu, Gaowa Jin

“…Next, the standard fingerprint chromatogram of XJC, which can reflect every herb material, was generated. Finally, quality markers were screened through unsupervised cluster analysis and supervised orthogonal partial least squares discrimination analysis. …”
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Truncated SPAG9 as a novel candidate gene for a new syndrome: Coarse facial features, albinism, cataract and developmental delay (CACD syndrome) by Majid Alfadhel, Bashayr S. Alhubayshi, Muhammad Umair, Ahmed Alfaidi, Deemah Alwadaani, Essra Aloyouni, Safdar Abbas, Abdulkareem Al Abdulrahman, Mohammed Aldrees, Abeer Al Tuwaijri, Ruaa S. Alharithy, Abdulaziz Alajlan, Abdulrahman Alswaid, Saad Almohrij, Sultan Al-Khenaizan

“…Abstract Sperm-associated antigen 9 (SPAG9) is a member of cancer-testis antigen, having characteristics of a scaffold protein, which is involved in the c-Jun N-terminal kinase JNK signaling pathway, suggesting its key involvement in different physiological processes, such as survival, apoptosis, tumorigenesis, and cell proliferation. …”
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An Overview of Solar Orbiter Observations of Interplanetary Shocks in Solar Cycle 25 by Domenico Trotta, Andrew Dimmock, Heli Hietala, Xochitl Blanco-Cano, Timothy S. Horbury, Rami Vainio, Nina Dresing, Immanuel Christopher Jebaraj, Francisco Espinosa Lara, Raúl Gómez-Herrero, Javier Rodriguez-Pacheco, Yulia Kartavykh, David Lario, Jan Gieseler, Miho Janvier, Milan Maksimovic, Nasrin Talebpour Sheshvan, Christopher J. Owen, Emilia K. J. Kilpua, Robert F. Wimmer-Schweingruber

“…Finally, we give details and guidance on the access use of the present survey, available on the EU-project “Solar Energetic Particle Analysis Platform for the Inner Heliosphere” website. …”
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Autism Spectrum Disorder Classification with Interpretability in Children Based on Structural MRI Features Extracted Using Contrastive Variational Autoencoder by Ruimin Ma, Ruitao Xie, Yanlin Wang, Jintao Meng, Yanjie Wei, Yunpeng Cai, Wenhui Xi, Yi Pan

“…In case of degraded predictive accuracy when data size is extremely small, a transfer learning strategy is proposed here as a potential solution. Finally, we conduct neuroanatomical interpretation based on the correlation between s-MRI features extracted from CVAE and surface area of different cortical regions, which discloses potential biomarkers that could help target treatments of ASD in the future.…”
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Mechanism of hyperbaric oxygen therapy downregulating H-type angiogenesis in subchondral bone of knee osteoarthritis through the PHD2/HIF-1α pathway by Jianjian Wang, Wen Yu, Yuxin Zhang, Bo Chen, Zhaoxiang Meng

“…The activation relationship between PHD2 and downstream signaling pathways was investigated through gene knockout and overexpression experiments. Finally, cell scratch assays, tube formation assays, and chondrogenic differentiation experiments were conducted to verify the mechanism of the PHD2/HIF-1α signaling pathway under hyperbaric oxygen stimulation. …”
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Silica Induces Changes in Cytosolic Free Calcium, Cytosolic pH, and Plasma Membrane Potential in Bovine Alveolar Macrophages by Attila Tárnok, Thomas Schlüter, Ingeborg Berg, Günther Gercken

“…Furthermore the calcium signal was quenched by Mn2+ and diminished by the calcium channel blocker verapamil. The protein kinase C specific inhibitor bisindolylmaleimide II (GF 109203 X) did not inhibit the silica‐induced [Ca2+]i rise. …”
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<i>VFL-Cafe</i>: Communication-Efficient Vertical Federated Learning via Dynamic Caching and Feature Selection by Jiahui Zhou, Han Liang, Tian Wu, Xiaoxi Zhang, Yu Jiang, Chee Wei Tan

“…Theoretical analysis is then conducted to provide guidance on cache configuration, optimizing performance. Finally, extensive experimental results validate <i>VFL-Cafe</i>’s efficacy, demonstrating remarkable improvements in communication efficiency and model accuracy.…”
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Usefulness of Low-Dose Splenic Irradiation prior to Reduced-Intensity Conditioning Regimen for Hematopoietic Stem Cell Transplantation in Elderly Patients with Myelofibrosis by Etsuko Matsubara, Jun Yamanouchi, Riko Kitazawa, Taichi Azuma, Hiroshi Fujiwara, Takaaki Hato, Masaki Yasukawa

“…The Janus kinase (JAK) 1 and 2 inhibitor, ruxolitinib, was recently approved in Japan and has been effective in many patients with myelofibrosis (MF). …”
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Evolutionary Algorithms and Quantum Computing: Recent Advances, Opportunities, and Challenges by Junaid Ur Rehman, Muhammad Shohibul Ulum, Abdurrahman Wachid Shaffar, Amirul Adlil Hakim, Mujirin, Zaid Abdullah, Hayder Al-Hraishawi, Symeon Chatzinotas, Hyundong Shin

“…Furthermore, we investigate the role of nature-inspired metaheuristics in enhancing the performance of noisy intermediate-scale quantum computers by fine-tuning their parameters. Finally, we discuss some of the recent progress at the intersection of both computing frameworks to highlight the current status and potential of the currently available quantum computing hardware. …”
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Regulatory role of S1P and its receptors in sepsis-induced liver injury by Bin Wang, Bin Wang, Xiaoyu Wu, Xiaoyu Wu, Jiangfeng Cheng, Jiangfeng Cheng, Junming Ye, Junming Ye, Hongquan Zhu, Hongquan Zhu, Xiaofeng Liu, Xiaofeng Liu

“…This paper focused on the mechanistic pathways through which S1P and its receptors modulate immunity, bile acid metabolism, and liver-intestinal circulation in septic liver injury. Finally, the relationships between S1P and its receptors with liver inflammation and metabolism and the use of related drugs for the treatment of liver injury were examined. …”
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Marginal Zone Lymphoma Complicated by Protein Losing Enteropathy by Nadine Stanek, Peter Bauerfeind, Guido Herzog, Henriette Heinrich, Matthias Sauter, Daniela Lenggenhager, Cäcilia Reiner, Markus G. Manz, Jeroen S. Goede, Benjamin Misselwitz

“…Additional treatments with steroids, octreotide, a diet devoid of long-chain fatty-acids, and parenteral nutrition did not prevent further clinical deterioration with marked weight loss (23 kg), further reduction in albumin concentrations (nadir 8 g/L), and a pronounced drop in performance status. Finally, immunochemotherapy with rituximab and bendamustine resulted in hematological remission and remarkable clinical improvement. 18 months after therapy the patient remains free of gastrointestinal complaints and has regained his body weight with normal albumin levels. …”
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