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18981
Vaccinomics Approach for Designing Potential Peptide Vaccine by Targeting Shigella spp. Serine Protease Autotransporter Subfamily Protein SigA
Published 2017-01-01“…From these, FHTVTVNTL and IELAGTLTL peptides were shown to have 100% conservancy. Finally, IELAGTLTL was shown to have the highest population coverage (83.86%) among the whole world population. …”
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18982
Normal tissue radioprotection by amifostine via Warburg-type effects
Published 2016-08-01“…Although amifostine in vitro did not inhibit the activity of the prolyl-hydroxylase PHD2, experiments with mouse liver showed that on a short timescale WR-1065 induced expression of the Hypoxia Inducible Factor HIF1α, lactate dehydrogenase LDH5, glucose transporter GLUT2, phosphorylated pyruvate dehydrogenase pPDH and PDH-kinase. This effect was confirmed on normal mouse NCTC hepatocytes, but not on hepatoma cells. …”
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18983
Microstructural Analysis and Radiological Characterization of Alkali-Activated Materials Based on Aluminosilicate Waste and Metakaolin
Published 2025-01-01“…Alkali-activated materials of aluminosilicate origin, made from the different ashes, fly and wood, are very attractive research targets and can be applied in various technological fields due to their thermal stability, resistance to thermal shock, high porosity, high sustainability, and finally, low energy loss during production. In this paper, we evaluate physico-chemical properties, microstructure, and radiological environmental impacts when wastes that contain elevated levels of naturally occurring radionuclides (NORs) such as fly ash and wood ash are made into “green cements” such as AAMs. …”
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18984
Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice
Published 2016-01-01“…In vitro results demonstrated that matrine significantly inhibited mitogen-activated protein kinase phosphorylation and decreased nuclear transcription factor kappa-B subunit p65 protein translocation into the nucleus. …”
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18985
Profiles of science process skills and sustainability awareness of junior high school students
Published 2024-12-01“…Instrumen yang digunakan yaitu soal pilihan ganda untuk mengukur tingkat keterampilan proses sains dan angket untuk mengetahui kesadaran minat siswa. Hasil penelitian menunjukkan bahwa keterampilan proses sains siswa masih berada pada tingkat cukup dengan perolehan persentase rata – rata 61,97, sedangkan tingkat persentase kesadaran menyukai siswa dalam kategori medium dengan perolehan persentase 66,2. …”
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18986
Chronic C-Type Natriuretic Peptide Infusion Attenuates Angiotensin II-Induced Myocardial Superoxide Production and Cardiac Remodeling
Published 2012-01-01“…CNP reduced Ang II-induced increases in cardiomyocyte size and interstitial fibrosis and suppressed hypertrophic- and fibrosis-related gene expression. Finally, CNP decreased Ang II-induced cardiac superoxide production. …”
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18987
A spatiotemporal distribution prediction model for electric vehicles charging load in transportation power coupled network
Published 2025-02-01“…Furthermore, the transportation-power coupled network is established based on the graph-theoretic analysis approach, and the spatial and temporal distribution characteristics of charging loads are predicted by Monte Carlo simulation. Finally, a case study is conducted in an actual urban region. …”
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18988
An urban land surface temperature and emissivity separation algorithm from ASTER TIR data and its application
Published 2025-12-01“…Three aspects are included: firstly, sing the XGBoost algorithm to estimate urban canopy bright temperature (BT) from 5 ASTER TIR top of atmosphere (TOA) BTs; secondly, employing an improved TES algorithm based on sky view factor (SVF) to separate LST and LSE; finally, the accuracy of the proposed algorithm is evaluated from simulation data. …”
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18989
Optimal WSN Deployment to Measure Air Quality in Dynamic Multi-Source Dispersion Scenarios: A Case Study in Arequipa
Published 2025-01-01“…Thus, to address this public health challenge, this article introduces a novel dynamic multi-source dispersion model that accounts for variations in wind velocity and direction over time, recognizing that air pollution is influenced by rapidly changing environmental factors. …”
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18990
Research advances of metal fluoride for energy conversion and storage
Published 2025-01-01“…In the field of water electrolysis, we focus on surface reconstruction and the critical role of fluorine, demonstrating the catalytic performance of metal fluorides from the perspectives of reconstruction mechanism and process analysis. Finally, we provide a summary and outlook for this field, aiming to offer guidance for future breakthroughs in the energy storage and conversion applications of metal fluorides.…”
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18991
Metastatic brain tumors: from development to cutting‐edge treatment
Published 2025-01-01“…For lung cancer, targeted therapy and immunotherapy have shown efficacy, while in breast cancer, monoclonal antibodies, tyrosine kinase inhibitors, and antibody–drug conjugates are effective in BM. …”
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18992
Free Pasture of Exotic Goats Reduces Diversity and Negatively Affects Body Condition in Scorpions (Arachnida: Scorpiones) Assemblage From Brazilian Seasonal Dry Tropical Forest
Published 2025-01-01“…Furthermore, in these sites, the composition of the species was also affected, with habitat‐generalist species favoring habitat‐specialist species. Finally, sites with free pasture of goats presented scorpions with reduced body condition (body mass and size) than sites without goats. …”
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18993
Multi-ancestry genome-wide meta-analysis with 472,819 individuals identifies 32 novel risk loci for psoriasis
Published 2025-01-01“…Gene-drug interaction analysis suggested that psoriasis-associated genes overlapped with targets of current medications for psoriasis. Finally, we used the multi-ancestry meta-analysis to explore drug repurposing and the potential targets for psoriasis. …”
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18994
Effect of Astaxanthin on Immune Function and Myocardial Injury in Mice with Chronic Sleep Deprivation
Published 2024-12-01“…Moreover, the levels of serum creatine kinase (CK), superoxide dismutase (SOD), tumor necrosis factor-α (TNF-α), glutathione peroxidase (GSH-Px), interleukin (IL)-1β, IL-6, nitric oxide synthase (NOS) and γ-glutamyl transpeptidase (γ-GT) rose markedly in each treatment group, and the level of malondialdehyde (MDA) significantly declined. …”
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18995
Big Data-Based Boring Indexes and Their Application during TBM Tunneling
Published 2021-01-01“…Subsequently, the defined boring indexes are verified using performance prediction of 291 cyclic tunneling processes. Finally, a preliminary application of support measure suggestions is conducted using the statistical features of boring indexes, where certain criteria are proposed and verified. …”
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18996
Comparison of Clinical Efficacy of Intravenous Acetaminophen with Intravenous Morphine in Acute Renal Colic: A Randomized, Double-Blind, Controlled Trial
Published 2014-01-01“…Intensity of pain was reassessed in 15, 30, 45, and 60 minutes according to VAS criteria. Finally, data from 108 patients were analyzed, 54 patients in each group. …”
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18997
Optically Transparent Anionic Nanofibrillar Cellulose Is Cytocompatible with Human Adipose Tissue-Derived Stem Cells and Allows Simple Imaging in 3D
Published 2019-01-01“…Moreover, it is shown that aNFC is cytocompatible, allowing for MSC proliferation, maintaining cell viability and multilineage differentiation potential. Finally, aNFC is compatible with scanning electron microscopy (SEM) and light microscopy including the application of conventional dyes, fluorescent probes, indirect immunocytochemistry, and calcium imaging. …”
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18998
Short-Term Changes in Fertility Attributes and Soil Organic Matter Caused by the Addition of EM Bokashis in Two Tropical Soils
Published 2015-01-01“…Particulate organic carbon (POC) and mineral-associated organic carbon (MOC) and total organic carbon (TOC) were also investigated. Finally, the Principal Component Analysis was conducted in order to identify possible patterns related to soils when fertilized with EM Bokashi. …”
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18999
Constructing the biomolecular networks associated with diabetic nephropathy and dissecting the effects of biomolecule variation underlying pathogenesis
Published 2024-11-01“…In the second step, we investigated the differential expression and co-expression of hub nodes in diseased and normal individuals, identifying lncRNA-mRNA relationships implicated in disease regulation. Finally, we gathered DN-related single nucleotide polymorphisms (SNPs) and lncRNAs from the LincSNP 3.0 database. …”
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19000
A scoping review on heat indices used to measure the effects of heat on maternal and perinatal health
Published 2024-04-01“…All studies demonstrate that certain socioeconomic factors influence the effect of heat on maternal and perinatal health outcomes.Conclusion We make three suggestions based on the results: (1) heat indices should be standardised across studies and explained. (2) An increased number of perinatal and maternal health outcomes explored. Finally, (3) enhanced collaboration across climate and health to improve understanding.…”
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