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18961
Development and Evaluation of Photoprotective O/W Emulsions Containing Hydroalcoholic Extract of Neoglaziovia variegata (Bromeliaceae)
Published 2017-01-01“…Nv-HA was incorporated in O/W emulsions in the presence or absence of synthetic filters and their photoprotective efficacy was evaluated by spectrophotometric SPF determination. Finally, the stability study of the formulations was performed through the freezing/defrosting method. …”
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18962
Brincidofovir Use after Foscarnet Crystal Nephropathy in a Kidney Transplant Recipient with Multiresistant Cytomegalovirus Infection
Published 2017-01-01“…A new course of foscarnet finally resulted in prolonged CMV remission. Herein, we present a review of foscarnet nephropathy cases in solid-organ transplanted patients. …”
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18963
Diffusion kinetics of boron in the X200CrMoV12 high-alloy steel
Published 2015-01-01“…A full factorial design with 2 factors at 3 levels was employed to estimate the total boride layer thickness as a function of the boriding parameters (time and temperature) and a simple equation was proposed. Finally, an iso-thickness diagram was given as a tool to predict the total boride layers thicknesses in relation with the practical utilization of this kind of steel.…”
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18964
Effect of Alkaloids from Nelumbinis Plumula against Insulin Resistance of High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease in Mice
Published 2016-01-01“…Further investigation indicated that NPA could inhibit IR by restoring the insulin receptor substrate-1 (IRS-1) and suppressing the expression of c-Jun N-terminal kinase (JNK) phosphorylation. The present results supported the view that the pathogenesis of NAFLD was complex with inflammation, together with increasing serum glucose and IR. …”
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18965
Alexithymia in multiple sclerosis: past, present and future
Published 2025-02-01“…This is followed by an analysis of neurobiological underpinnings of alexithymia derived from neurophysiological and neuroimaging studies in this clinical population. Finally, we provide perspectives to guide future research exploring and managing alexithymia in MS.…”
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18966
A Search for Radio Millisecond Pulsar Companions around Extremely Low-mass White Dwarfs with Ellipsoidal Variability
Published 2025-01-01“…In this study, we selected ∼12,000 ELM WDs or their candidates, and searched for ellipsoidal-like lightcurves with orbital periods shorter than 1 day, by using the public data from Zwicky Transient Facility. Finally, 23 such systems were found, with 17 being newly discovered. …”
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18967
An Imaging Method for Marine Targets in Corner Reflector Jamming Scenario Based on Time–Frequency Analysis and Modified Clean Technique
Published 2025-01-01“…Compared with the existing imaging methods, the proposed method can adapt to the different Doppler distribution characteristics of the ship target and the corner reflector array, thus realizing better robustness in obtaining a well-focused target image. Finally, simulation experiments verify the effectiveness of the algorithm.…”
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18968
A Simple Separation Method of the Protein and Polystyrene Bead-Labeled Protein for Enhancing the Performance of Fluorescent Sensor
Published 2018-01-01“…In the optimized condition, the relative AIF was observed approximately 4.908 ± 0.299. Finally, in 3 μm and 15 μm hole, the AIFs were approximately 3.143 and −1.346 by 2 nm of protein and about −2.515 and 4.211 by 30 nm of the PS beads, respectively. …”
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18969
The Role of Oxidized Low-Density Lipoproteins in Atherosclerosis: The Myths and the Facts
Published 2013-01-01“…The evidence coming from cohort studies demonstrating an association between oxidized LDLs and cardiovascular events, notwithstanding some discrepancies, seems to point towards a role of oxidized LDLs in atherosclerotic plaque development and destabilization. Finally, the results of randomized clinical trials employing antioxidants completed up to date, despite demonstrating no benefits in healthy populations, suggest a benefit in high-risk patients. …”
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18970
Effect of Ultrasonic Treatment on the in Vitro Digestibility Properties of Black Bean Protein
Published 2025-02-01“…The solubility, emulsification, absolute value of Zeta potential of black bean protein were promoted. Finally, the digestibility of black bean protein was improved, the in vitro digestibility of black bean protein increased from 66.50% to 90.9%. …”
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18971
Explainable machine learning framework for cataracts recognition using visual features
Published 2025-01-01“…Subsequently, the SHapley Additive exPlanations and Pearson correlation coefficient methods are applied to analyze the feature importance and select significant visual features. Finally, an ensemble multi-class ridge regression method is applied to recognize the cataracts severity levels based on the selected visual features. …”
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18972
Whole-Genome Duplication and Purifying Selection Contributes to the Functional Redundancy of Auxin Response Factor (ARF) Genes in Foxtail Millet (Setaria italica L.)
Published 2021-01-01“…Intrinsic disorder was featured in the middle regions of ARF activators. Finally, expression profiles of SiARFs under hormone and abiotic stress treatment not only revealed their potential function in stress response but also indicate their functional redundancy. …”
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18973
Extracellular vesicles—a new player in the development of urinary bladder cancer
Published 2025-01-01“…EVs isolated from urinary bladder cancer cells affect other lower-grade cancer cells or normal cells by inducing different metabolic pathways (transforming growth factor β/Smads pathway; phosphoinositide 3-kinase/Akt pathway) that promote epithelial–mesenchymal transition. …”
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18974
Peroxisome Proliferator-Activated Receptor α Reduces Endothelin-1-Caused Cardiomyocyte Hypertrophy by Inhibiting Nuclear Factor-κB and Adiponectin
Published 2016-01-01“…We examined the activation of extracellular signal-regulated kinase (ERK) and p38 proteins caused by ET-1 and the inhibition of the ERK and p38 pathways on ET-1-induced cell size and adiponectin expression. …”
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18975
Tripartite organization of brain state dynamics underlying spoken narrative comprehension
Published 2025-01-01“…Speech comprehension involves the dynamic interplay of multiple cognitive processes, from basic sound perception, to linguistic encoding, and finally to complex semantic-conceptual interpretations. …”
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18976
Fibroblast Growth Factor 18 Increases the Trophic Effects of Bone Marrow Mesenchymal Stem Cells on Chondrocytes Isolated from Late Stage Osteoarthritic Patients
Published 2014-01-01“…Results from transwell coculture study showed that expression of matrix producing genes in OA chondrocytes increased when cocultured with MSCs with FGF18 in culture medium, while hypertrophic genes were not changed by coculture. Finally, coimplantation of MSCs with OA chondrocytes produces more matrix than chondrocytes only. …”
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18977
Single-cell sequencing provides clues about the developmental genetic basis of evolutionary adaptations in syngnathid fishes
Published 2025-02-01“…We found no evidence for tooth primordia cells, and we observed re-deployment of osteoblast genetic networks in developing dermal armor. Finally, we found that epidermal cells expressed nutrient processing and environmental sensing genes, potentially relevant for the brooding environment. …”
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18978
Strain Rockbursts Simulated by Low-Strength Brittle Equivalent Materials
Published 2016-01-01“…Test results showed that, with an initial state of high stress from both upper layers’ gravitational effects and in situ stress due to tectonic movements, the excavation brings a dramatic rise in the hoop stress and sharp drop in radial stress, which leads to the splitting failure of rock mass. Finally a rockburst occurred associated with the release of strain energy stored in highly stressed rock mass. …”
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18979
The Research and Mechanism of Extracting Vitamin B6 Using Aqueous Two-Phase Systems
Published 2020-01-01“…It was demonstrated that temperature has no influence in binodal curves and the salting-out ability follows the order Na2CO3 > Na2SO4. Finally, we chose the best system (isopropyl alcohol + ethanol + Na2CO3 + H2O) to find out the extraction efficiency when dealing with vitamin B6. …”
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18980
Olive Oil Total Phenolic Contents and Sensory Sensations Trends during Oven and Microwave Heating Processes and Their Discrimination Using an Electronic Tongue
Published 2018-01-01“…Besides, bitter, fruity, green, and pungent intensities showed a linear dependency with the total phenolic contents (0.8075≤R-Pearson ≤ 0.9694). Finally, the potentiometric electronic tongue together with linear discriminant analysis-simulated annealing algorithm allowed satisfactory discrimination (sensitivities of 94±4%, for repeated K-fold cross-validation) of olive oils subjected to intense microwave heating (5–10 min, 160–205°C) from those processed under usual cooking conditions (oven heating during 15–60 min or microwave heating during 1.5–3 min, 72–165°C). …”
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