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18901
Subsequent commutation failure suppression strategy of hybrid cascaded HVDC system based on coordinated control of CEC and VDCOL
Published 2024-12-01“…Secondly, aiming at the problem of power return between MMC after VDCOL regulation, the new VDCOL control curve is coordinated to improve the MMC control strategy to ensure stable recovery during system failure. Finally, the simulation model is built in PSCAD/EMTDC simulation environment. …”
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18902
Fatigue failure mechanisms and life prediction of additive manufactured metallic lattices: a comprehensive review
Published 2025-12-01“…The study also delves into the fatigue behaviours influenced by specific configurations and loading conditions, categorises the factors impacting fatigue failure in lattice materials, and presents a comprehensive review of fatigue life prediction methods, derived from an enhanced understanding of the fatigue process and the development of progressive fatigue failure algorithms. Finally, the current research advancements and limitations are discussed to provide a clearer perspective on the fatigue challenges associated with AM metallic lattice materials.…”
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18903
Mycobiology of Dental Unit Water: A Systematic Scoping Review
Published 2025-02-01“…This highlights the pressing need for continued research efforts to develop new and optimized treatment protocols that are specifically tailored to eradicate fungi from DUWLs. Finally, it was notable that there are currently no specific regulations by any dental authority on permissible levels of fungi, as opposed to bacteria, in DUWLs. …”
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18904
High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease
Published 2013-01-01“…In this study, we investigated the mRNA and protein levels of IL-12p40, tumor necrosis factor-like cytokine 1A (TL1A), Janus kinase 2 (JAK2), and IL-23R both locally and systemically in Chinese IBD patients. …”
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18905
OMP38 of Carbapenem‐Resistant Acinetobacter Baumannii‐Mediated mtDNA Release Activates the cGAS‐STING Signaling to Induce Inflammatory Response
Published 2025-01-01“…Intriguingly, CRAB utilized outer membrane vesicles (OMVs) to transport outer membrane protein 38 (OMP38) into mitochondria, triggering mitochondrial DNA (mtDNA) release into the cytosol through the mitochondrial permeability transition pore (mPTP) and activating the cGAS‐STING signaling. Finally, epigallocatechin gallate (EGCG) is demonstrated to block the activation of the cGAS‐STING pathway and ameliorate CRAB‐induced excessive inflammatory response. …”
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18906
A Secure and Efficient White-Box Implementation of SM4
Published 2024-12-01“…Furthermore, theoretical analysis shows that the techniques employed in our scheme effectively prevent existing algebraic attacks. Finally, our design requires only 1.44 MB of memory, significantly less than that of the known DCA-resistant schemes—Zhang et al.’s scheme (24.3 MB), Yuan et al.’s scheme (34.5 MB) and Zhao et al.’s scheme (7.8 MB). …”
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18907
Run-Time Value Chain Analysis and Cost Accounting via Microservices in Agile Manufacturing
Published 2025-01-01“…In contrast, the second focuses on constructing efficient manufacturing activities based on product requirements, allowing for granular analysis of costs and production times across microservices, activities, broader business processes, and finally, cost objects (e.g., customized products, batches of products, or customer invoices). …”
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18908
Exploiting the Achilles’ Heel of Viral RNA Processing to Develop Novel Antivirals
Published 2024-12-01“…As with HIV-1, 5342191’s inhibition of coronaviruses and influenza is mediated through the activation of specific cell signaling networks, including GPCR and/or MAPK signaling pathways that ultimately affect SR kinase expression. Together, these studies highlight the therapeutic potential of compounds that target cellular processes essential for the replication of multiple viruses. …”
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18909
Disturbance Observer-Based Super-Twisting SMC for Variable Speed Wind Energy Conversion System Under Parametric Uncertainties
Published 2025-01-01Subjects: Get full text
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18910
Esophageal Gastrointestinal Stromal Tumor with Rare Intracranial Metastasis
Published 2020-01-01“…Our patient lived for 13 years with excellent disease control with imatinib, but the fact that it does not cross the blood-brain barrier makes it not useful in preventing or treating brain lesions. New tyrosine kinase inhibitors that may cross the blood-brain barrier could be the answer to these cases.…”
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18911
Review of Adaptive Cell Selection Techniques in LTE-Advanced Heterogeneous Networks
Published 2016-01-01“…Moreover, more accurate cell load estimation is obtained in the extended RBUR adaptive CRE bias technique through constant bit rate (CBR) traffic, which further improved load balancing as against the estimation based on the number of user equipment (UE). Finally, this paper presents suggestions for future research directions.…”
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18912
On the imbalance of international communications
Published 2022-11-01“…This study attempts to illustrate the fundamental problems, to ex- plore the consequences of communication imbalance, and to examine communication dysfunctions in order to provide a set of solutions specifically addressed to the ell- mination or the reduction of the detrimental effects of communication dysfunctions. …”
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18913
ChromaFold predicts the 3D contact map from single-cell chromatin accessibility
Published 2024-11-01“…Compared to leading contact map prediction models that use ATAC-seq and CTCF ChIP-seq, ChromaFold achieves state-of-the-art performance using only scATAC-seq. Finally, fine-tuning ChromaFold on paired scATAC-seq and Hi-C in a complex tissue enables deconvolution of chromatin interactions across cell subpopulations.…”
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18914
The Neuroprotective Disease-Modifying Potential of Psychotropics in Parkinson's Disease
Published 2012-01-01“…The most promising neuroprotective investigative priorities will involve disease-modifying trials of the safest agents alone or in combination to capture salutary effects on H3 histone deacetylase, gene transcription, glycogen synthase kinase-3, α-synuclein, reactive oxygen species (ROS), reactive nitrogen species (RNS), apoptosis, inflammation, and trophic factors including GDNF and BDNF.…”
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18915
Ester-Based Lubricant and Anti-Leidenfrost Additive Solutions on Aluminum High-Pressure Die-Casting Applications
Published 2025-01-01“…Additionally, a pilot plant methodology for testing newly formulated lubricants has been established while the experimental methodology developed for assessing heat-transfer capability is validated as a rapid and cost-effective approach for evaluating lubrication alternatives for high-pressure die-casting applications. Finally, the efficiency of environmentally friendly ester-based lubricants for high-temperature applications has been demonstrated.…”
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18916
The Impact of Bioactive Lipids on Cardiovascular Development
Published 2011-01-01“…LPA stimulates the clonal expansion of neurospheres from neural stem/progenitor cells and induces c-fos via activation of mitogen- and stress-activated protein kinase 1 (MSK1) in ES cells. S1P acts on hematopoietic progenitor cells as a chemotactic factor and has also been found to be critical for cardiac and skeletal muscle regeneration. …”
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18917
Determination of Crizotinib in Mouse Tissues by LC-MS/MS and Its Application to a Tissue Distribution Study
Published 2020-01-01“…Toxicity induced by crizotinib, a small-molecule tyrosine kinase inhibitor, is a significant clinical issue during treatment. …”
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18918
Changes in Proteinuria on the Risk of All-Cause Mortality in People with Diabetes or Prediabetes: A Prospective Cohort Study
Published 2017-01-01“…A total of 17,878 participants were finally included in this study. There were 1193 deaths after a median follow-up of 6.69 years. …”
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18919
Inhibition of GSK3β is synthetic lethal with FHIT loss in lung cancer by blocking homologous recombination repair
Published 2025-01-01“…Here, we report that inhibitors of glycogen synthase kinase 3 beta (GSK3β) and the homologous recombination DNA repair (HRR) pathway are synthetic lethal with FHIT loss in lung cancer. …”
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18920
Characteristics of the IBEX Ribbon and Their Implications for a Source Region Outside the Heliopause
Published 2025-01-01Subjects: Get full text
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