Flow Control of Flow Boiling Experimental System by Whale Optimization Algorithm (WOA) Improved Single Neuron PID by Yan Li, Miao Qian, Daojing Dai, Weitao Wu, Le Liu, Haonan Zhou, Zhong Xiang

“…The WOA-improved single-neuron PID (1.01 s) exhibited a faster return to a stable state compared to the traditional PID (2.46 s) and fuzzy PID (1.28 s). Finally, the effectiveness of the algorithm is validated through practical application. …”
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Harmonic Analysis of the Spatiotemporal Pattern of Thunderstorms in Iran (1961–2010) by Ali Akbar Sabziparvar, Seyed Hossein Mir Mousavi, Mostafa Karampour, Mehdi Doostkamian, Esmaeil Haghighi, Iman Rousta, Haraldur Olafsson, Md Omar Sarif, Rajan Dev Gupta, Md Moniruzzaman, Khairul Hasan, Ali Ghasemi

“…Furthermore, in order to conduct the calculations, programming facilities of MATLAB have been explored. Finally, Surfer and GIS were employed to come up with the graphical depiction of the maps. …”
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Effects of Microbes on Insect Host Physiology and Behavior Mediated by the Host Immune System by Shan Zhang, Zhengyan Wang, Qiong Luo, Lizhen Zhou, Xin Du, Yonglin Ren

“…Toll, immune deficiency, and Janus kinase/signal transducers and activators of transcription are the main signaling pathways regulating insect humoral immunity. …”
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AI-driven 3D bioprinting for regenerative medicine: From bench to bedside by Zhenrui Zhang, Xianhao Zhou, Yongcong Fang, Zhuo Xiong, Ting Zhang

“…This paper further describes specific AI applications in 3D bioprinting's key elements, including bioink formulation, model structure, printing process, and function regulation. Finally, the paper discusses current prospects and challenges associated with AI technologies to further advance the clinical translation of 3D bioprinting.…”
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Myeloid Neoplasms with t(5;12) and ETV6-ACSL6 Gene Fusion, Potential Mimickers of Myeloid Neoplasm with PDGFRB Rearrangement: Case Report with Imatinib Therapy and Review of the Li... by Javier De Luca-Johnson, Jose I. Ruades Ninfea, Lauren Pearson, Joanna Conant, Ronald Bryant, Neil A. Zakai, Mary E. Tang

“…In particular, while tyrosine kinase inhibitor therapy is effective in patients with PDGFRB rearrangement, there is little information on imatinib efficacy in patients with ETV6-ACSL6 gene fusion. …”
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Increased Incidence of Thyroid Dysfunction and Autoimmunity in Patients with Vernal Keratoconjunctivitis by Stefano Stagi, Neri Pucci, Laura Di Grande, Cinzia de Libero, Roberto Caputo, Stefano Pantano, Ivan Mattei, Francesca Mori, Maurizio de Martino, Elio Novembre

“…Subclinical hypothyroidism was diagnosed in 6.6% (versus 1.6% of the controls; P<0.05) and overt hypothyroidism in 0.7% (versus 0.0% of the controls; P=NS). Finally, 5.2% of patients were positive for thyroid autoantibodies, which were significantly higher with respect to the controls (0.5%, P<0.05). …”
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Research on the Effect of Geometric Parameters on the Stress Concentration Factor of Multi-Planar KK-Joints and Carbon Fiber-Reinforced Polymer Wrapping Rehabilitation with Numeric... by Yuhao Shi, Peng Deng, Shiqi Zhao, Yan Liu, Zhongyi Zhu, Yunkai Chen

“…Analysis of the effects of different layers and directions of polymer wrap revealed that even six layers of wrapping effectively reduced the stress concentration compared to the initial model. Finally, based on the results of parametric analysis and nonlinear fitting, a calculation formula for the stress concentration factor suitable for KK-joints under axial loads is proposed.…”
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Belzutifan for the treatment of renal cell carcinoma by Xiancheng Wu, David Lazris, Risa Wong, Scott S. Tykodi

“…Belzutifan has demonstrated activity in clinical trials as a front- and later-line therapy, and in combination with tyrosine kinase inhibitors. It has been largely well tolerated, although anemia represents a common on-target side effect and, along with hypoxia, requires monitoring during treatment. …”
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Oral Administration of Oleuropein and Its Semisynthetic Peracetylated Derivative Prevents Hepatic Steatosis, Hyperinsulinemia, and Weight Gain in Mice Fed with High Fat Cafeteria D... by Saverio Massimo Lepore, Valeria Maria Morittu, Marilena Celano, Francesca Trimboli, Manuela Oliverio, Antonio Procopio, Carla Di Loreto, Giuseppe Damante, Domenico Britti, Stefania Bulotta, Diego Russo

“…Also, Ole and Ac-Ole prevented the development of hepatic steatosis. Finally, Ole and Ac-Ole determined a lower increase of HDL and LDL-cholesterol levels and corrected caf diet-induced elevation of plasma glucose concentrations by improving insulin sensitivity. …”
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Bioinformatics approach reveals the critical role of inflammation-related genes in age-related hearing loss by Xi Gu, Chenyu Chen, Yuqing Chen, Chaojun Zeng, Yanchun Lin, Ruosi Guo, Shujin Xu, Chang Lin

“…By CIBERSORT algorithm, 8 humanized key IRDEGs were correlated with the infiltration abundance of 3 immune cells. Finally, it showed that the Alox5ap expression was significantly more effective compared to other variables in the diagnostic model of ARHL. …”
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Antileishmanial Effect of 5,3′-Hydroxy-7,4′-dimethoxyflavanone of Picramnia gracilis Tul. (Picramniaceae) Fruit: In Vitro and In Vivo Studies by Sara M. Robledo, Wilson Cardona, Karen Ligardo, Jéssica Henao, Natalia Arbeláez, Andrés Montoya, Fernando Alzate, Juan M. Pérez, Victor Arango, Iván D. Vélez, Jairo Sáez

“…The leishmanicidal activity attributed to this flavanone is also reported for the first time. Finally, the in vitro and in vivo leishmanicidal activity reported here for 5,3′-hydroxy-7,4′-dimethoxyflavanone offers a greater prospect towards antileishmanial drug discovery and development.…”
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GFTT: Geographical Feature Tokenization Transformer for SAR-to-Optical Image Translation by Hongbo Liang, Xuezhi Yang, Xiangyu Yang, Jinjin Luo, Jiajia Zhu

“…In addition, we leverage a self-supervisory task to encourage the transformer to learn meaningful semantic correspondence from local and global style patterns. Finally, we utilize the noise-contrastive estimation loss to maximize mutual information between the input and translated image. …”
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Time-dependent model for in-situ concrete carbonation depth under combined effects of temperature and relative humidity by Ting Du, Yongjia Cai, Yipu Guo, Jinghao Chen, Sen Chen, Mofang Yuan, Fulin Qu

“…Moreover, sensitivity analysis reveals a noticeable variation in sensitivity factors related to temperature and relative humidity after a 28-day carbonation period, with the sensitivity factor for temperature being higher than that for relative humidity. Finally, by employing the Sensitivity Analysis and Least-Square Fitting (SA-LSF) method, a novel model is developed that incorporates both temperature and relative humidity as influential factors in predicting carbonation depth under diverse environmental conditions. …”
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Development and validation of the Chinese Rural Middle-aged and Elderly Health Literacy Scale by Rui Li, Fei Wang, Jie Huang, Zhengyu Wu, Wenjuan Gong, Yoshida Koki, Yi-Chen Chiang, Maoming Jiang, Jiannan Ma, Zhengkui Liu, Dewen Wang

“…Third, pretesting was used to assess the rationality of the item settings within the CREHLS. Finally, a large-sample survey was used to assess the reliability and validity of the finalisation CREHLS.Results The CREHLS, which comprises 26 items distributed across four dimensions, is designed to evaluate the capacity to access, comprehend, assess and apply pertinent health information related to disease treatment, disease prevention, health promotion and environmental health. …”
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Accurate and optimal control of a bidirectional DC-DC converter: A robust adaptive approach enhanced by particle swarm optimization by Julius Derghe Cham, Francis Lénine Djanna Koffi, Alexandre Teplaira Boum, Ambe Harrison, Paul Michael Dongmo Zemgue, Njimboh Henry Alombah

“…Furthermore, by thoroughly comparing its performance against existing controllers such as conventional sliding mode controller, super-twisting sliding mode controller, adaptive sliding mode controller, this paper aims to emphasize the superiority of the proposed controller in achieving accurate and robust performance of the Half-bridge bidirectional DC-DC converter. Finally, experimental results were provided to validate the proposed controller in real time.…”
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Evidence That ADAM17 Mediates the Protective Action of CGRP against Angiotensin II-Induced Inflammation in Vascular Smooth Muscle Cells by Si-yu Zeng, Li Yang, Chen-liang Hong, Hui-qin Lu, Qiu-jiang Yan, Yan Chen, Xu-ping Qin

“…Small interference RNA (siRNA) and inhibitors of CGRP, epidermal growth factor receptor (EGFR), and extracellular signal-regulated kinase 1/2 (ERK1/2) were adopted to investigate their effect on Ang II-induced inflammation in VSMCs. …”
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Algorithm of Strawberry Disease Recognition Based on Deep Convolutional Neural Network by Li Ma, Xueliang Guo, Shuke Zhao, Doudou Yin, Yiyi Fu, Peiqi Duan, Bingbing Wang, Li Zhang

“…In this paper, based on the deep convolution neural network technology, the recognition of strawberry common diseases was studied, as well as a new method based on deep convolution neural network (DCNN) strawberry disease recognition algorithm, through the normal training of strawberry image feature representation in different scenes, and then through the application of transfer learning method, the strawberry disease image features are added to the training set, and finally the features are classified and recognized to achieve the goal of disease recognition. …”
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Overcoming beta-lactam resistance in Pseudomonas aeruginosa by targeting metallo-beta-lactamase VIM-1: a one-microsecond molecular dynamics simulation study by Mohammed Salleh M. Ardawi, Samar A. Badreddine, Muhammad Yasir, Muhammad Yasir, Aiah M. Khateb, Aiah M. Khateb, Safaa A. Turkistani, Ahmed Afandi, Samah O. Noor, Adhari Alselmi, Adhari Alselmi, Vivek Dhar Dwivedi, Vivek Dhar Dwivedi, Esam I. Azhar, Esam I. Azhar

“…These compounds were then subjected to re-docking and one-microsecond molecular dynamics (MD) simulations to assess their binding stability and interactions within the MBL-VIM-1 active site. Finally, post-MD simulation calculations were employed to estimate the interaction strengths and compare the efficacy of these compounds against the reference inhibitor. …”
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Promising LOX proteins for cartilage-targeting osteoarthritis therapy by Luca Morici, Eric Allémann, Olivier Jordan, Ines Nikolić

“…Lectin-like oxidized low-density lipoprotein family are receptors located at the surface of chondrocytes, which interact with their ligand, ox-LDL, activating several catabolic pathways involved in OA pathophysiology. Finally, lysyl oxidase and lysyl oxidase-like are enzymes expressed intracellularly (in chondrocytes' cytoplasm) involved in elastin biosynthesis and collagen cross-linking in cartilage extracellular matrix. …”
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The Maternal Microbiome Programs the m6A Epitranscriptome of the Mouse Fetal Brain and Intestine by Zhuoyu Xiao, Sun Liu, Zengguang Li, Jinru Cui, Hailan Wang, Zihan Wang, Qihuan Ren, Laixin Xia, Zhijian Wang, Yuan Li

“…From the m6A profiles, we identified 2,655 and 2,252 m6A modifications regulated by the maternal microbiome in the fetal brain and intestine, respectively, and we demonstrated that these m6A-modified genes were enriched in the neuro/intestinal developmental pathways, such as the Wnt signaling pathway. Finally, we verified that antibiotic treatment mostly recapitulated changes in m6A, and we further showed that the loss of heterozygosity of Mettl3 rescued m6A levels and the expression changes of some developmental genes in the fetal intestine that resulted from antibiotic treatment. …”
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