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18861
Recent advances of the thermodynamic behavior of tin species in aqueous solution
Published 2023-01-01“…Additionally, the potential-pH diagram of Sn/H2O system at different temperatures (298 K, 373 K, and 550 K), dissolved Sn activities (1, 10−1, 10−3, and 10−6), and the potential-pH diagram of the Sn species in a chloridion aqueous solution (Sn/H2O-Cl) was summarized. Finally, the application prospect of the potential-pH diagram for Sn/H2O system was investigated in the intelligent simulation of Sn metallurgy and the practical application of Sn materials.…”
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18862
Disruptive mood dysregulation disorder, parental stress, and attachment styles
Published 2024-07-01“…Furthermore, parents of children with DMDD show a higher association with insecure adult attachment styles than parents of children without DMDD. Finally, an adult preoccupied-ambivalent attachment style explains the variability in parental stress in the DMDD group to a large degree. …”
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18863
Nonviral targeted mRNA delivery: principles, progresses, and challenges
Published 2025-01-01“…In this review, we first described the physiological barriers in the process of mRNA delivery and then discussed the design approach and recent advances in mRNA delivery systems with an emphasis on their tissue/cell‐targeted abilities. Finally, we pointed out the existing challenges and future directions with deep insights into the design of efficient mRNA delivery systems. …”
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18864
Effects of oxidation and precursors (lysine, glyoxal and Schiff base) on the formation of Nε-carboxymethyl-lysine in aged, stored and thermally treated chicken meat
Published 2022-09-01“…As post-mortem ageing and storage time increased, the CML content in cooked chicken breast significantly increased from 1.81 mg/kg to 2.00 mg/kg during 0−6 h, and then decreased from 2.00 mg/kg to 1.80 mg/kg during 6 h−1 day, finally increased again during 1−7 days, while the CML contents of raw and cooked leg significantly and continuously increased from 1.78 mg/kg to 2.08 mg/kg. …”
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18865
Effect of adhesive on the anchorage performance of variable curvature waveform clamping anchor for CFRP plate: Experimental investigation and carrying capacity calculation
Published 2025-07-01“…Then, a carrying capacity calculating method for friction-bending coupling anchoring was established based on the mechanism of the bending effect. Finally, by integrating the friction-bending coupling process with friction-adhesion coupling process, a carrying capacity calculating method for the friction-bending-adhesion coupling anchoring was proposed. …”
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18866
BSG-WSL: BackScatter-guided weakly supervised learning for water mapping in SAR images
Published 2025-02-01“…Then, a morphological pseudo-label optimization algorithm is designed to employ CAMs to generate high-quality pseudo-labels. Finally, a confidence cross-entropy loss is introduced to utilize pseudo-labels to train the extraction model and achieve precise water extraction in different scenarios. …”
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18867
The Structural, Biophysical, and Antigenic Characterization of the Goose Parvovirus Capsid
Published 2025-01-01“…As a member of the genus <i>Dependoparvovirus</i>, GPV could also be bound by cross-reactive anti-AAV capsid antibodies that bind to the five-fold region of the viruses, as shown by native immuno-dot blot analysis. Finally, the GPV VP structure was compared to those of other bird dependoparvoviruses, which revealed that VR-III may be important for GPV and Muscovy duck parvovirus (MDPV) infection.…”
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18868
Characterization of HIV-1 Infection and Innate Sensing in Different Types of Primary Human Monocyte-Derived Macrophages
Published 2013-01-01“…By contrast, all MDM types were activated to a comparable extent by intracellular DNA, and the macrophage serum-free medium-(Mac-SFM-)differentiated MDMs responded strongly to membrane fusion through expression of CXCL10. Finally, we found that HIV infection of RPMI/M-CSF-differentiated MDMs induced low-grade expression of two interferon-stimulated genes in some donors. …”
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18869
An Unusual Case of Systemic Inflammatory Myofibroblastic Tumor with Successful Treatment with ALK-Inhibitor
Published 2014-01-01“…Tumor cells showed immunoreactivity for smooth muscle actin and anaplastic lymphoma kinase 1 (ALK1). Tissue from the L5 vertebra showed a process histologically identical to that seen in the liver. …”
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18870
An Investigation of Manifold-Based Direct Control for a Brain-to-Body Neural Bypass
Published 2024-01-01“…By daily recalibrating only scaling factors, we achieved rapid learning and stable high performance in simple, incremental 2D tasks over more than 12 weeks of experiments. Finally, we showed that this brain decoding strategy can be effectively coupled to peripheral nerve stimulation to trigger voluntary hand movements. …”
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18871
Learning Power Systems Waveform Incipient Patterns Through Few-Shot Meta-Learning
Published 2024-01-01“…Next, at the meta-training stage, an adaptability-enhancing weighting initialization strategy is constructed to address the data differences between the meta-training stage and IF detection stage. Finally, an IF detection model based on convolutional neural networks (CNNs) is obtained through the fine-tuning process. …”
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18872
Occurrence of antibiotics and antibiotic resistance genes at various stages of different aquaculture modes surrounding Tai Lake, China
Published 2025-01-01“…These findings will support the optimization of aquaculture mode and antibiotic usage to the green and sustainable development of aquaculture finally.…”
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18873
Real-Time G-Protein-Coupled Receptor Imaging to Understand and Quantify Receptor Dynamics
Published 2011-01-01“…A study of short-term dynamics of the long isoform of the dopamine type 2 receptor revealed an agonist-induced increase in the mobile fraction of receptors with a rate of movement of 0.08 μm/s For long-term assays, the ratio between the relative fluorescence intensity at the cell surface versus that in the intracellular compartment indicated that receptor internalization only occurred in cells co-expressing G protein-coupled receptor kinase 2. These results indicate that the lateral movement of receptors and receptor internalization are not directly coupled. …”
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18874
Cathepsin C Is Involved in Macrophage M1 Polarization via p38/MAPK Pathway in Sudden Cardiac Death
Published 2021-01-01“…Western blotting was carried out to measure the expressions of cathepsin C (CTSC), focal adhesion kinase (FAK), p-FAK, and proteins related to the p38/MAPK signaling pathway, whereas immunohistochemistry was performed to determine the localization and expression of CTSC, TNF-α, and CD206 in arterial tissues. …”
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18875
Cardiac function and quality of life improvement with fasudil hydrochloride in patients with diabetes post-PCI: a randomized controlled trial
Published 2025-02-01“…Objective We assessed the efficacy of fasudil hydrochloride, a Rho-kinase inhibitor, as adjunct therapy for enhancing cardiac function, managing blood sugar, and improving quality of life in patients with diabetes who have coronary heart disease (CHD) and who underwent percutaneous coronary intervention (PCI). …”
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18876
New derivatives of sulfonylhydrazone as potential antitumor agents: Design, synthesis and cheminformatics evaluation
Published 2021-12-01“…Phosphoinositide 3-kinase α (PI3Kα) is a propitious target for designing anticancer drugs. …”
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18877
Machine learning potential predictor of idiopathic pulmonary fibrosis
Published 2025-01-01“…Furthermore, GSEA revealed enrichment in multiple pathways, while immune function analysis demonstrated a significant correlation between IPF onset and immune cell infiltration. Finally, the roles of PODNL1 and PIGA as biomarkers were validated through in vivo and in vitro experiments using qRT-PCR, Western blotting, and immunohistochemistry.ResultsThese findings suggest that PODNL1 and PIGA may serve as critical biomarkers for IPF onset and contribute to its pathogenesis.DiscussionThis study highlights their potential for early biomarker discovery and risk prediction in IPF, offering insights into disease mechanisms and diagnostic strategies.…”
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18878
Spatial–Temporal Analysis of Coupling Coordination Between New Urbanization and Ecological Environment in Ya’an, China
Published 2025-01-01“…The coupling coordination degree (CCD) and relative development degree (RDD) models are applied to analyze spatial and temporal changes in new urbanization and the ecological environment in Ya’an from 2011 to 2021. Finally, spatial autocorrelation and geographically weighted regression (GWR) models are combined to analyze the factors influencing coupling coordination degree differences among Ya’an’s districts and counties. …”
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18879
Discovering the Graph-Based Flow Patterns of Car Tourists Using License Plate Data: A Case Study in Shenzhen, China
Published 2020-01-01“…Next, daily graphs of tourist movements between road segments and tourist attractions are constructed. Finally, a frequent subgraph mining algorithm is used to extract the flow patterns of car tourists. …”
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18880
Luminescent Lanthanide Infinite Coordination Polymers for Ratiometric Sensing Applications
Published 2025-01-01“…This ratiometric approach is particularly suitable for detecting trace analytes and for use in complex environments where factors like background noise, temperature fluctuations, and light intensity variations may affect the results. Finally, we outline future research directions for improving the design and synthesis of ratiometric Ln-CPs, such as incorporating long-lifetime reference luminescent molecules, exploring near-infrared emission systems, and developing up-conversion or two-photon luminescent materials. …”
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