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18721
A Comprehensive Review of the Diversity of Fungal Secondary Metabolites and Their Emerging Applications in Healthcare and Environment
Published 2024-11-01“…Investigators further highlighted the importance of omics technologies in understanding the regulation and biosynthesis of SMs, which offers an understanding of novel applications in drug discovery and sustainable agriculture. Finally, the authors have addressed the potential for genetic manipulation and biotechnological innovations for further exploitation of fungal SMs for commercial and environmental benefits.…”
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18722
Auditory decision-making deficits after permanent noise-induced hearing loss
Published 2025-01-01“…Our findings demonstrate NIHL diminished perceptual acuity, reduced attentional focus, altered choice bias, and slowed down evidence accumulation speed. Finally, video-tracking analysis of motor behavior during task performance demonstrates that NIHL can impact sensory-guided decision-based motor execution. …”
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18723
Analyzing and Estimating Thermal Conductivity of Sedimentary Rocks from Mineral Composition and Pore Property
Published 2021-01-01“…Compaction diagenesis enhances bulk thermal conductivity of sedimentary rocks, particularly sandstones, by decreasing the rock porosity and mineral particle size. Finally, correction factors with respect to mineral grains were proposed to correct the thermal resistance of intergrain contacts and degree of intactness of crystals, and an optimized formula was adopted to calculate the thermal conductivity of sedimentary rock based on rock structure and mineral constituents.…”
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18724
Biochemical and antioxidant responses of common carp (Cyprinus carpio) exposed to sublethal concentrations of the antiepileptic and analgesic drug gabapentin
Published 2025-01-01“…The exposure to the highest two concentrations resulted in significant changes in plasma indices such as glucose (only group 100 μg/l), alanine aminotransferase (ALT), lactate dehydrogenase (LDH), lipase, creatine kinase (CK), amylase as well as butyrylcholinesterase (BChE). …”
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18725
A Double Resistive–Capacitive Approach for the Analysis of a Hybrid Battery–Ultracapacitor Integration Study
Published 2025-01-01“…Limitations of the proposed models are also discussed. Finally, the main advantages of HESSs are highlighted in terms of energy and open-circuit voltage (OCV) characteristics.…”
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18726
Analysis of Aerosol Type and Fine- and Coarse-mode Aerosol Direct Radiative Forcing over Regions in East and Southeast Asia Based on AERONET Version 3 Data
Published 2021-03-01“…Also, the lowest values for both the radiative forcing and the radiative forcing efficiency in southern China occurred during summer. Finally, the various aerosol constituents displayed distinct spatial and temporal distributions in Southeast Asia, with the SA aerosol contributing approximately 20% of the total aerosol on the Indochinese Peninsula and the NA and WA aerosol forming the largest percentages on the Malay Peninsula.…”
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18727
Acute Deterioration of Pulmonary Arterial Hypertension (PAH) in a Patient with Neurofibromatosis Type 1 (NF1)
Published 2019-01-01“…A plastic surgeon removed one of the neurofibromas and pathologically diagnosed it as neurofibromatosis type 1 (NF1). We finally rediagnosed her with pulmonary hypertension with unclear and/or multifactorial factors when she deteriorated 1 year after being treated only with bronchodilators. …”
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18728
Association of nutrients intake during pregnancy with the risk of allergic disease in offspring: a meta-analysis of prospective cohort studies
Published 2023-05-01“…Moreover, high β-carotene and magnesium intakes during pregnancy were related to lower eczema risk in offspring, whereas eczema risk in offspring was increased for pregnant women with high intake of butter and margarine. Finally, the asthma risk in offspring could protect against for pregnant women with high intake of vitamin D and apple, whereas high folic acid during pregnancy could produce excess asthma risk in offspring. …”
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18729
Mechanisms of nucleus accumbens deep brain stimulation in treating mental disorders
Published 2025-01-01“…., predominantly GABAergic and dopaminergic systems) and anatomical pathways that have been shown to be relevant for NAc DBS stimulation effects, we aim to further elucidate the neurobiological determinants of NAc DBS efficacy. Finally, since treatment effects of NAc DBS are most probably also related to alterations in NAc connected circuits or networks, we review studies focusing on the investigation of NAc DBS network effects. …”
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18730
Sustained Release of Prostaglandin E2 in Fibroblasts Expressing Ectopically Cyclooxygenase 2 Impairs P2Y-Dependent Ca2+-Mobilization
Published 2014-01-01“…The inhibition of P2Y responses by PGE2 involves the activation of PKCs and PKD, a response that can be suppressed after pharmacological inhibition of these protein kinases. In addition to this, PGE2 reduces the fibroblast migration induced by P2Y-agonists such as UTP. …”
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18731
Extraction of Features due to Breathing Crack from Vibration Response of Rotated Blades considering Tenon Connection and Shroud Contact
Published 2019-01-01“…Next, the stiffness of the blade trunk with a breathing crack is analyzed. Finally, the vibration response of blade trunks with the occurrence of breathing crack is analyzed in time and frequency domains by numerical simulation. …”
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18732
A Meta-Analysis for Association of Maternal Smoking with Childhood Refractive Error and Amblyopia
Published 2016-01-01“…Potential publication bias was finally examined by Egger’s test. Results. A total of 9 articles were included in this meta-analysis. …”
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18733
Blood Plasma of Patients with Parkinson’s Disease Increases Alpha-Synuclein Aggregation and Neurotoxicity
Published 2016-01-01“…This was supported by the observations that phosphorylated α-syn oligomers entered neurons, rapidly increased accumulated thioflavin S-positive inclusions, and induced a series of metabolic changes that included activation of polo-like kinase 2, inhibition of glucocerebrosidase and protein phosphatase 2A, and reduction of ceramide levels, all of which have been shown to promote α-syn phosphorylation and aggregation. …”
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18734
Current biomarkers of prostate cancer
Published 2021-12-01“…And with the increase in their availability, finally, the possibility of an individual approach to the appointment of treatment for men with prostate cancer appears on the horizon. …”
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18735
Proteomic Profiling of Ex Vivo Expanded CD34-Positive Haematopoetic Cells Derived from Umbilical Cord Blood
Published 2013-01-01“…In the presented publications, CD34-positive cells were isolated from cord blood and expanded for up to 7 days in media supplemented with stem cell factor (SCF), thrombopoietin (THPO), interleukin 6 (IL-6), and fms-related tyrosine kinase 3 ligand (FLT3lg). At days 3 and 7, expanded cells were harvested and analyzed by flow cytometry and quantitative proteomics. 2970 proteins were identified, whereof proteomic analysis showed 440 proteins significantly changed in abundance during ex vivo expansion. …”
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18736
Theoretical modeling of RF ablation with internally cooled electrodes:Comparative study of different thermal boundary conditions at theelectrode-tissue interface
Published 2009-05-01“…In the NC cases,this overestimation was more evident for higher values of theconvective heat transfer coefficient ($h$). Finally, with NC, when$h$ was increased the temperature profiles became more similar tothose with DC. …”
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18737
Decomposition of the Methylene Blue Dye Using Layered Manganese Oxide Materials Synthesized by Solid State Reactions
Published 2018-01-01“…For example, the layered manganese oxides material synthesized at 400°C, using a heating rate of 10°C/min, showed the highest AC conductivity and had the best performance in the degradation of methylene blue. Finally, we propose a general mechanism for understanding how manganese oxides behave as catalysts that produce oxidizing species from H2O2 which degrades methylene blue. …”
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18738
Chronic Inflammation and Neutrophil Activation as Possible Causes of Joint Diseases in Ballet Dancers
Published 2014-01-01“…Herein, we investigated the effects of a ballet class on the kinetic profiles of creatine kinase (CK) and lactate dehydrogenase (LDH) activities, cytokines, complement component 3 (C3), and the concentrations of immunoglobulin (Ig), IgA and IgM, in ballerinas. …”
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18739
Research on Hydraulic Fracturing Pressure Relief Technology in the Deep High-Stress Roadway for Surrounding Rock Control
Published 2021-01-01“…In this study, the working face 14203 of the Zaoquan coal mine was taken as the engineering background, the deformation mechanism of surrounding rock in the deep-buried high-stress roadway was analyzed, and the hydraulic fracturing pressure relief technology in the advanced roadway was proposed for surrounding rock control. Finally, the numerical simulation and field tests were used to validate the comprehensive effect of the proposed technology. …”
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18740
Neural mechanisms of non-pharmacological interventions in patients with mild cognitive impairment and Alzheimer's disease: An ALE meta-analysis
Published 2025-02-01“…Secondly, in the MCI group there was increased activation in the precuneus and precentral gyrus after treatment, whereas there was decreased activation in the anterior cingulate gyrus; in the AD group there was only increased activation after treatment, including in the lingual gyrus and bilateral superior temporal gyrus. Finally, the bilateral cuneus and precentral gyrus showed increased activation after cognitive training, while bilateral insula, among others, showed decreased activation. …”
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