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  1. 1821
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    Emergency Evacuation of Hazardous Chemical Accidents Based on Diffusion Simulation by Jiang-Hua Zhang, Hai-Yue Liu, Rui Zhu, Yang Liu

    Published 2017-01-01
    “…We then verify the validity and feasibility of the algorithm using Jinan, China, as a computational example. In the end, we compare the results from different scenarios to explore the key factors affecting the effectiveness of the evacuation process.…”
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  3. 1823
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    Addressing Methodological and Generalizability Challenges in Cervical Rotation-Traction Manipulation (CRTM) for Cervical Radiculopathy [Letter] by Wang R, Xv M, Yao L

    Published 2025-01-01
    “…Ruixue Wang,1 Mingzhu Xv,2 Lin Yao3 1Innovation Research Institute of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China; 2Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of China; 3Institute of Acupuncture and Moxibustion, Shandong University of Traditional Chinese Medicine, Jinan, 250355, People’s Republic of ChinaCorrespondence: Lin Yao, Changqing Campus, Shandong University of Traditional Chinese Medicine, No. 4655 University Road, Guyun Lake Street, Changqing District, Jinan, Shandong, People’s Republic of China, Email yaolin@sdutcm.edu.cn…”
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    Population pharmacokinetics of iruplinalkib in healthy volunteers and patients with solid tumors by Guihong Yang, Yimei Wang, Huimin Zhao, Ziyi Jiang, Shansong Zheng, Mingjing Ge, Meimei Si, Xiaoyan Kang

    Published 2025-01-01
    “…Abstract Iruplinalkib (WX‐0593), a selective oral ALK/ROS1 tyrosine kinase inhibitor, was approved in China as first‐line therapy for ALK‐positive non‐small‐cell lung cancer (NSCLC) and for the treatment of locally advanced or metastatic ALK‐positive NSCLC that has progressed following crizotinib therapy. …”
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  12. 1832
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    Knock-In Mice with Myo3a Y137C Mutation Displayed Progressive Hearing Loss and Hair Cell Degeneration in the Inner Ear by Peipei Li, Zongzhuang Wen, Guangkai Zhang, Aizhen Zhang, Xiaolong Fu, Jiangang Gao

    Published 2018-01-01
    “…To investigate the mechanism of DFNB30-type deafness, we established a mouse model of Myo3a kinase domain Y137C mutation by using CRISPR/Cas9 system. …”
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  15. 1835
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    Numerical Simulation and Optimization Design of End-Suspended Pile Support for Soil-Rock Composite Foundation Pit by Qingchao Xu, Zhenhao Bao, Tu Lu, Huarui Gao, Jiakang Song

    Published 2021-01-01
    “…In order to design the soil-rock combination foundation pit more safely and effectively, this paper presents the investigations of the mechanical and deformational characteristics of end-suspended piles supporting the structures in Jinan CBD area. Based on the measured data, a finite element model was established through the two-dimensional numerical simulation method to study the deformational characteristics of the end-suspended piles, and the influences of the depth of socketed rock, the width of rock shoulder, and the prestress of anchor cables on the deformations and mechanical property of end-suspended piles were discussed. …”
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  18. 1838
  19. 1839

    The Effect of Irisin as a Metabolic Regulator and Its Therapeutic Potential for Obesity by Hui Li, Fang Wang, Mu Yang, Jiao Sun, Yi Zhao, Dongqi Tang

    Published 2021-01-01
    “…Furthermore, we also described the potential anti-inflammatory properties of irisin under a variety of inflammatory conditions. Finally, the review discussed the existing unresolved issues and controversies about irisin, including the transcription of the irisin precursor FNDC5 gene in humans, the cleavage site of the yet unknown proteolytic enzyme that cleaves irisin from FNDC5, and the reliability of irisin levels measured with available detection methods.…”
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  20. 1840

    Evolution Mechanism, Monitoring, and Early Warning Method of Water Inrush in Deep-Buried Long Tunnel by Wenfeng Tu, Liping Li, Shuai Cheng, Diyang Chen, Yongcai Yuan, Yanhao Chen

    Published 2021-01-01
    “…By analyzing the evolution law of multi-information in the process of water inrush, the evolution model and its identification method are put forward. Finally, the level of water inrush was determined through the analysis of the dynamic and static reserves of disaster source, and a multilevel and comprehensive warning system of tunnel water inrush is established. …”
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