Model of fuzzy risk assessment of the information system by ZHAO Dong-mei1, MA Jian-feng1, WANG Yue-sheng2

“…A model of risk assessment was introduced to the estimation of the information system.The method,which combined AHP and fuzzy logical method,was applied to the risk assessment.AHP and fuzzy logical method were altered according to the actual condition of the risk assessment of information system.Applying fuzzy logical method,the im-portant degree of each factor was judged in the aspects of the probability,the impact severity and uncontrollability,not judged immediately.Finally,the risk value of each factor was calculated.By comparing the risk value of each factor,it is known that which risk can take measures to control.By introducing entropy,the proportion of each risk factor in the whole risk assessment system was calculated.Next the risk degree of the whole system was calculated.Then the risk level of the whole system can be determined.The study of the case shows that the model can be easily used to the risk assessment of the information system security.The results are in accord with the reality.…”
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Analysis and suggestions on inter-satellite laser communication of satellite Internet by Shanzhi CHEN, Zhiwen FAN, Jiade JIN, Yun CAO

“…Satellite communication and terrestrial mobile communication have strong complemented co-benefits.Satellite Internet is the hot spot supporting current industrial development and an important part of the future 6G network.Global coverage requires interstellar networking, but inter-satellite communication bandwidth requirements and the instability brought by the free space channel pose new challenges to the space bearer network.Inter-satellite communication technologies and link interface technologies were compared and analyzed.An optical transport network (OTN) carrier network solution based on inter-satellite laser was proposed, which could fully leverage the advantages of the maturities and the economies of the scaled ground optical communication.It constructs a satellite-terrestrial integrated network with strong cost-efectivity, compatibility, and scalability.Finally, the technological directions and evolutions of the inter-satellite laser communication were discussed, and suggestions for industrial development in China were proposed.…”
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Blockchain-based secure and fair crowdsourcing scheme by Junwei Zhang, Wenxuan Cui, Jianfeng Ma, Chao Yang

“…The analysis results show that our scheme can satisfy the above requirements. Finally, the experimental results show that the computational overhead of the BFC scheme is acceptable to both the requester and the workers. …”
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Design and Prototype of an Automated Temperature Monitoring System for Kisoro Farmers’ Storage Facilities. by Nizeyimana, Denis

“…Hardware components include Arduino Uno, LM35 temperature sensor, SIM800A GSM, buzzer, LEDs (red and blue), and LCD, and the software component includes the Arduino IDE, Proteus. Finally, the whole system is tested, and the test results show that the system has the characteristics of remote viewing, high measuring accuracy, and convenient use, and the system could meet the needs of temperature management for Kisoro farmers’ storage facilities.…”
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Caracterización genética de aislamientos de SARS-CoV-2 en las diferentes etapas pandémicas de COVID-19 en Cuba by Liuber Yans Machado Zaldívar, Enrique Noa Romero, Laura Sofía López Rizo, Madeline Blanco de Armas, Nibaldo Luis González Sosa, Juliet Enríquez Puertas, Dania Romay Franchi, María Teresa Pérez Guevara, Danay Carrillo Valdés, Marta Dubed Echevarría, Otto Cruz Sui, Mireida Rodríguez Acosta

“…El 33,3 % de los aislamientos secuenciados correspondieron a los diferentes linajes de la variante Ómicron, seguido de la variante Beta B 1.351 (29,6 %), otros linajes de SARS-CoV-2 (25,9 %), Alfa B 1.1.7 (7,4 %) y Delta B.1.575 (3,7 %). …”
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Analysis on the Difference of Energy Evolution in the Process of Energy Storage Failure of Strong Coal Rush Rock Samples under Different Adaptive Modification Regulation Measures by Fangfang Zhang

“…However, we should focus on the defects of the corresponding control measures and finally try to make a reasonable combination of different modification measures. …”
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Identification of mitophagy-related key genes and their correlation with immune cell infiltration in acute myocardial infarction via bioinformatics analysis by Zulong Sheng, Rui Zhang, Zhenjun Ji, Zhuyuan Liu, Yaqing Zhou

“…We also explored the interactions between the key genes themselves or with miRNAs/transcription factors (TFs) and drug compounds and visualized the protein structure of the key genes. Finally, we explored and validated the expression of key genes in plasma samples of patients with an AMI and healthy individuals.ResultsWe screened 28 MRDEGs in AMI. …”
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Comparing some blood parameters of ski racers and long-distance athletes by Banu Can, Metin Bayram, Gökhan Bayraktar, Harun Akyol

“…There are meaningful differences between the control and athlete groups and between control and skier groups in terms of Creatinine Kinase value (p=0.00). There was not any significant correlation between the groups compared to the other parameters. …”
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Cancer-associated fibroblasts induce almonertinib resistance in non-small cell lung cancer by Guohao Wei, Yu Nie, Min Sun, Wenzheng Zhou, Huihui Zhao, Fangfang Chen, Chuandong Zhu

“…Differential gene expression analysis, along with GO and KEGG enrichment analyses, was performed to predict the potential mechanisms underlying resistance to third-generation EGFR-TKIs. Finally, qPCR and Western blot analyses were used to explore the signaling pathways by which CAFs induce resistance to almonertinib in NSCLC cells. …”
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Dapagliflozin improves diabetic kidney disease by inhibiting ferroptosis through β-hydroxybutyrate production by Yan Tian, Chenxia Zhou, Qun Yan, Ziyi Li, Da Chen, Bo Feng, Jun Song

“…In addition, the role of the β-hydroxybutyrate- Calcium/Calmodulin Dependent Protein Kinase Kinase 2 (BHB-CaMKK2) axis in mediating dapagliflozin regulating ferroptosis was examined.Results Dapagliflozin significantly ameliorated kidney injury in mice with DKD. …”
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Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPARδ in obesity and diabetes by Yizhen Bai, Dechao Tan, Qiaowen Deng, Lingchao Miao, Yuehan Wang, Yan Zhou, Yifan Yang, Shengpeng Wang, Chi Teng Vong, Wai San Cheang

“…Western blotting results indicated that CA treatment upregulated the expression of peroxisome proliferator-activated receptor delta (PPARδ), and activated nuclear factor erythroid 2-related factor 2 (Nrf2)/ heme oxygenase-1 (HO-1) and AMP-activated protein kinase (AMPK)/ protein kinase B (Akt)/ endothelial nitric oxide synthase (eNOS) signaling pathways in mouse aortas in vivo and ex vivo. …”
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Contractile Protein Expression and Phosphorylation and Contractility of Gastric Smooth Muscles from Obese Patients and Patients with Obesity and Diabetes by Wen Li, Kent C. Sasse, Yulia Bayguinov, Sean M. Ward, Brian A. Perrino

“…Fundus and antrum muscles were obtained from sleeve gastrectomies and were used in in vitro myobath contractile studies and for capillary electrophoresis and immunodetection of γ-actin, CPI-17, pT38-CPI-17, MYPT1, pT853-MYPT1, pT696-MYPT1, myosin light chain (MYL9), pS19-MYL9, myosin light chain kinase (MYLK), protein phosphatase-1δ (PP1δ), and Rho-associated kinase (ROCK2). …”
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RETRACTED ARTICLE: Synthesis of silver nanoparticles using Plantago lanceolata extract and assessing their antibacterial and antioxidant activities by Muhammad Zahir Shah, Zheng-Hui Guan, Ala Ud Din, Amjad Ali, Ata Ur Rehman, Kashif Jan, Shah Faisal, Shah Saud, Muhammad Adnan, Fazli Wahid, Saud Alamri, Manzer H. Siddiqui, Shamsher Ali, Wajid Nasim, Hafiz Mohkum Hammad, Shah Fahad

“…NPs showed efficient activity as compared to ACE, and finally, the bacterial growth was impaired by biogenic NPs. …”
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Variables associated with cognitive function: an exposome-wide and mendelian randomization analysis by Yong-Li Zhao, Yi-Ning Hao, Yi-Jun Ge, Yi Zhang, Lang-Yu Huang, Yan Fu, Dan-Dan Zhang, Ya-Nan Ou, Xi-Peng Cao, Jian-Feng Feng, Wei Cheng, Lan Tan, Jin-Tai Yu

“…Methods Our study included 164,463 non-demented adults (89,644 [54.51%] female; mean [SD] age, 56.69 [8.14] years) from the UK Biobank who completed four cognitive assessments at baseline. 364 variables were finally extracted for analysis through a rigorous screening process. …”
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Evaluation of Safety and Efficacy of a Single Lorecivivint Injection in Patients with Knee Osteoarthritis: A Multicenter, Observational Extension Trial by Christopher J. Swearingen, Jeyanesh R. S. Tambiah, Ismail Simsek, Heli Ghandehari, Sarah Kennedy, Yusuf Yazici

“…Abstract Introduction Lorecivivint (LOR), a CDC-like kinase/dual-specificity tyrosine kinase (CLK/DYRK) inhibitor thought to modulate inflammatory and Wnt pathways, is being developed as a potential intra-articular knee osteoarthritis (OA) treatment. …”
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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by Graham McIlroy, Charlotte Gaskell, Aimee Jackson, Emily Yafai, Rachel Tasker, Catherine Thomas, Sonia Fox, Rebecca Boucher, Fitsum Ghebretinsea, Claire Harrison, Adam J. Mead, Mary Frances McMullin

“…The most frequent gene mutation found in patients is JAK2 V617F, causing constitutive activation of the kinase and activation of downstream signalling. Fedratinib is an oral selective JAK2 inhibitor. …”
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The Effects of Different Challenge-Level Balance Tasks on Stroke Cortical Responses and Balance Assessment Using EEG by Rui Xu, Yu Bai, Jun Liang, Ningning Wang, Yongzheng He, Lin Meng, Dong Ming

“…The pairwise-derived Brain Symmetry Index (pdBSI), and Granger Causality (GC) were analyzed with a two-way (task <inline-formula> <tex-math notation="LaTeX">$\times $ </tex-math></inline-formula> group) RMANOVA. Finally, a multiple linear regression analysis was applied to predict the BBS score with the above parameters. …”
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Delivery of dendritic cells targeting 3M2e-HA2 nanoparticles with a CpG adjuvant via lysosomal escape of Salmonella enhances protection against H9N2 avian influenza virus by Futing Jia, Wenfeng Wang, Yawen Tian, Ainul Zahra, Yingkai He, Chongbo Ge, Tongyu Zhang, Mingyue Wang, Jingshuo Gong, Gerui Zhang, Guilian Yang, Wentao Yang, Chunwei Shi, Jianzhong Wang, Haibin Huang, Xin Cao, Yang Zeng, Nan Wang, Zhannan Wang, Chunfeng Wang, Yanlong Jiang

“…The chicken dendritic cells (DCs) targeting the nanobody phage-54 were then fused to HA2-3M2e to yield pYL327. Finally, a synthesized 20-repeat CpG adjuvant gene fragment was inserted into pYL327, resulting in the plasmid pYL331. …”
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Identification of prognostic biomarker of non-small cell lung cancer based on mitochondrial permeability transition-driven necrosis-related genes and determination of anti-tumor ef... by Zhifei Ma, Wen Chen, Aiping Zhang, Xiaokang Shen, Lin Zheng

“…Three biomarkers with prognostic values were finally screened, including ARL14, ZDHHC11B, and HLF. …”
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Peel of pumpkin (Cucurbita pepo) diets boost growth, digestive-absorptive functions, immune-antioxidant indices, and regulate immunomodulatory genes and mTOR/MAPK-P38/apoptosis sig... by Rowida E. Ibrahim, Gehad E. Elshopakey, Elsayed M. Younis, Abdelwahab A. Abdelwarith, Asmaa Yaseen, Tarek Khamis, Simon J. Davies, Afaf N. Abdel Rahman

“…CPP diets caused down-regulation (P˂0.05) of the splenic expression of the tumor suppressor gene (P53), mitogen-activated protein kinase (P38), caspase-9, and mechanistic target of rapamycin. …”
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