Deformed wing virus coopts the host arginine kinase to enhance its fitness in honey bees (Apis mellifera) by Andrea Becchimanzi, Giovanna De Leva, Rosanna Mattossovich, Serena Camerini, Marialuisa Casella, Giovanni Jesu, Ilaria Di Lelio, Sabrina Di Giorgi, Joachim R. de Miranda, Anna Valenti, Silvia Gigliotti, Francesco Pennacchio

“…Abstract Background Deformed wing virus (DWV) is a major honey bee pathogen that is actively transmitted by the parasitic mite Varroa destructor and plays a primary role in Apis mellifera winter colony losses. …”
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Remodeling of tumor microenvironments by EGFR tyrosine kinase inhibitors in EGFR-mutant non-small cell lung cancer by Soomin Kim, Jaemoon Koh, Tae Min Kim, Songji Oh, Soyeon Kim, Jeonghwan Youk, Miso Kim, Bhumsuk Keam, Yoon Kyung Jeon, Dong-Wan Kim, Dae Seog Heo

“…We used digital spatial profiling to analyze non-small cell lung carcinomas in 25 patients before and after EGFR tyrosine kinase inhibitor (TKI) treatment, including 14 patients treated with first-line osimertinib, focusing on CD45-positive immune regions and pan-cytokeratin-positive tumor regions. …”
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Tierra y crédito en la diócesis de Guatemala a finales de la época colonial by Christophe Belaubre

“…A partir del ejemplo de la diócesis de Guatemala intentamos esbozar algunos elementos para medir el peso real de los censos en la economía colonial en el contexto de crisis económica que marcó el Reino a finales del siglo XVIII: ¿el peso de los censos pudo haber movilizado una parte de las elites criollas para construir un discurso anti-clerical?…”
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Dual band four port MIMO antenna with dual circular polarization for Wi-Fi/WiMAX applications by Poonam Thanki, Trushit Upadhyaya, Upesh Patel, Khaled Aliqab, Meshari Alsharari, Ayman A. Althuwayb, Ammar Armghan, Vishal Sorathiya

“…The planar compact four port circularly polarized printed MIMO antenna described in this article is small and intended to support Wi-Fi and WiMAX applications. Suggested four E-shaped monopole elements make up the dual circularly polarized (CP) MIMO antenna that has two left hand CP (LHCP) elements and two right hand CP (RHCP) elements. …”
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Cardiovascular safety of Janus kinase inhibitors in inflammatory bowel disease: a systematic review and network meta-analysis by Huibin Yang, Ting An, Yuxuan Zhao, Xiaojing Shi, Bangmao Wang, Qingyu Zhang

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Evaluasi penggunaan tepung cangkang rajungan sebagai bahan baku pakan juwana udang windu Penaeus monodon by Agus Kurnia, Wellem H Muskita, Oce Astuti, , Asnani, Wulandari Harahap

“…Hasil penelitian ini menyimpulkan bahwa tepung cangkang rajungan dapat digunakan sebagai bahan pakan sumber protein dalam pakan juvenile udang windu.   Kata kunci: penggantian bahan, tepung cangkang rajungan, tepung ikan, udang windu …”
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Uridine-cytidine kinase 2 is correlated with immune, DNA damage repair and promotion of cancer stemness in pan-cancer by Jinlong Tian, Yanlei Li, Yu Tong, Yuan Zhang, Tingxiao Zhao, Yao Kang, Qing Bi

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Glycogen Synthase Kinase-3 Regulates Production of Amyloid-β Peptides and Tau Phosphorylation in Diabetic Rat Brain by Zhong-Sen Qu, Liang Li, Xiao-Jiang Sun, Yu-Wu Zhao, Jin Zhang, Zhi Geng, Jian-Liang Fu, Qing-Guo Ren

“…Diabetes mellitus (DM) and Alzheimer’s disease (AD) are characterized by amyloid deposits. Glycogen synthase kinase-3 (GSK-3) plays an important role in the pathogenesis of AD and DM. …”
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Patients outcomes in lung adenocarcinoma transforming to small-cell lung cancer after tyrosine kinase inhibitor therapy by Shuai Wang, Yongsen Wang, Xuan Wu, Li Yang, Xiaoju Zhang

“…Abstract Background Non-small cell lung cancer (NSCLC) transforming to small cell lung cancer (SCLC) is one of the mechanisms of resistance to tyrosine kinase inhibitors (TKIs). Cases of NSCLC transforming into SCLC have been discovered. …”
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Mucocutaneous Adverse Events in Patients With Cancer Treated with the Highly Selective RET Kinase Inhibitor Selpercatinib (LOXO-292) by Rachel E. Reingold, MD, Rose Parisi, MD, MBA, Guilherme Harada, MD, Andrea P. Moy, MD, George Dranitsaris, PhD, Jasmine H. Francis, MD, Julia Canestraro, OD, FAAO, Julia A. Lester, MPH, Lauren A. Kaplanis, RN, Dazhi Liu, PharmD, BCOP, Mario E. Lacouture, MD, Alexander Drilon, MD

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RETROSPECTIVE ET ANALYSE DEMOGRAPHIQUE DE LA DYNAMIQUE URBAINE DU SYSTEME WILAYAL TEBESSI (1966–2008) by MEDARAG NAROU BOUBIR HANA, FARHI ABDELLAH

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Treatment time and learning curve analysis of 1.5 T MR-Linac workflows led by radiation oncologists or therapists by J.M. Westerhoff, F.J. Raaijmakers, L.A. Daamen, E.N. de Groot-van Breugel, L.T.C. Meijers, J.R.N. van der Voort van Zyp, J.J.C. Verhoeff, S. Mook, H.M. Verkooijen, M.P.W. Intven

“…Materials and methods: This study was conducted utilizing the prospective Multi-OutcoMe EvaluatioN of radiation Therapy Using the MR-Linac study (MOMENTUM, NCT04075305). Mean (±standard deviation) online adaptation time and total treatment time were collected from MR-Linac log files. …”
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Manifestação do lúdico nas aulas de educação física nas séries finais do ensino fundamental by Débora Cristina Pereira Ciesca, Arestides Pereira da Silva Júnior

“…Desta forma, o objetivo do presente estudo é apresentar a manifestação do lúdico nas aulas de Educação Física nas séries finais do Ensino Fundamental. A referida pesquisa caracterizou-se como de cunho descritivo com abordagem qualitativa, em que o relato dos professores foi a essência para o seu desenvolvimento. …”
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Exploring novel and potent glycogen synthase kinase-3β inhibitors through systematic drug designing approach by Shabir Ahmad Ganai, Suma Mohan, Shahid Ahmad Padder

“…Abstract Significant implications of glycogen synthase kinase-3β (GSK-3β) have been reported in various neuronal disorders and malignant cancers. …”
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Systematic Literature Review: Pengaruh Media Pembelajaran Keberagaman Budaya pada Minat dan Hasil Belajar Siswa by Olive Olyssia, Nasution Nasution, Ganes Gunansyah

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“Linajes de embustes”: cargas de centurias y tiempos universales en el mundo maya colonial by Mario Humberto Ruz

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Late Emergence of an Imatinib-Resistant ABL1 Kinase Domain Mutation in a Patient with Chronic Myeloid Leukemia by Mireille Crampe, Claire Andrews, Anne Fortune, Stephen E. Langabeer

“…The introduction of the tyrosine kinase inhibitor (TKI) imatinib has revolutionised the outlook of chronic myeloid leukemia (CML); however, a significant proportion of patients develop resistance through several mechanisms, of which acquisition of ABL1 kinase domain mutations is prevalent. …”
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Meningkatkan Minat Belajar Siswa Sekolah Dasar dalam Sains Melalui Integrasi Model SAVI-Mind Mapping by Mokhammad Rizqi Zidane, Putri Arwinda Putri, M. Muhlis, Nadia Putri Mulyani Posangi, Nurma Yuliana

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Winter observations of Eurasian Lynx (Lynx lynx) inspecting karst caves and dolines in the Northern Dinaric Mountains, Slovenia by Miha Krofel

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Functional interaction between receptor tyrosine kinase MET and ETS transcription factors promotes prostate cancer progression by Elisa Carouge, Clémence Burnichon, Martin Figeac, Shéhérazade Sebda, Nathalie Vanpouille, Audrey Vinchent, Marie‐José Truong, Martine Duterque‐Coquillaud, David Tulasne, Anne Chotteau‐Lelièvre

“…Finally, by performing a comparative transcriptomic analysis, we identify target genes that could play a relevant role in these cellular processes. …”
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