Counting the cost of hospitalised injury using administrative data in Australia: three considerations from a retrospective cohort data linkage study by Jacelle Warren, Kirsten Vallmuur, Victoria McCreanor, Steven M McPhail, Shahera Banu, Michael Schuetz, Clifford Afoakwah

“…CPI-inflated costs were significantly lower than health group index-inflated estimates, with observed differences between 7.7% (95% CI 6.9% to 8.7%) and 11.9% (95% CI 10.8% to 13.1%) for the same AR-DRG. Finally, cost estimates were significantly higher for care funded by private health insurers compared with care funded by either the public insurer or compulsory third-party injury insurers, with differences varying significantly between 8.4% (95% CI 7.2% to 30.1%) and 55.0% (95% CI 53.3% to 56.9%) for the same AR-DRG. …”
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Transposon-sequencing across multiple Mycobacterium abscessus isolates reveals significant functional genomic diversity among strains by Chidiebere Akusobi, Sanjeevani Choudhery, Bouchra S. Benghomari, Ian D. Wolf, Shreya Singhvi, Thomas R. Ioerger, Eric J. Rubin

“…We also identified genes whose requirements were subspecies, lineage, and isolate-specific. Finally, by correlating TnSeq profiles, we identified 19 previously uncharacterized genetic networks in Mab. …”
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Characteristics of Stratum Structure and Fracture Evolution in Stratified Mining of Shallow Buried High-Gas-Thick Coal Seam by Similarity Simulation by Qin Guangpeng, Cao Jing, Wang Chao, Wu Shuo, Zhai Minghua

“…In the process of stratified mining of ultrathick coal seam, the main fissure of overburden is mainly longitudinal fissure, and it is very easy to form through with the upper layer and will finally connect with the surface under the condition of shallow buried depth. …”
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Efficacy and safety of ketamine and esketamine in reducing the incidence of postpartum depression: an updated systematic review and meta-analysis by Moaz Yasser Darwish, Abdallah A. Helal, Yousif Ahmed Othman, Manar Alaa Mabrouk, Aya Alrawi, Taha Abd-ElSalam Ashraf, Nada K. Abdelsattar, Fatma Mohammed Sayed, Mohamed Abd-ElGawad

“…We extracted PPD occurrence rate, PPD score, pain score and side effects. Finally, a meta-analysis was conducted using RevMan software. …”
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La villégiature anglaise et l’invention de la Côte d’Azur by Alain Bottaro

“…Then such first-hand observations were appropriated by others through literary or iconographic representations such as travelogues or vedute. Finally came « launch time », as the expression goes: that is, the progressive inclusion of local towns in the ranks of top resorts for international travelers. …”
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Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer by Luis Aparicio, Laura Crowley, John R. Christin, Caroline J. Laplaca, Hanina Hibshoosh, Raul Rabadan, Michael M. Shen

“…Notably, we detect copy number variants predominantly within luminal acinar cells in prostate tumors, suggesting a bias in their cell type of origin, as well as a larger field of transcriptomic alterations in non-tumor cells. Finally, we observe that luminal acinar tumor cells in treatment-naïve prostate cancer display heterogeneous androgen receptor (AR) signaling activity, including a split between AR-positive and AR-low profiles with similarity to PrU-like states. …”
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UPLC-MS/MS Method for Givinostat in Rat Plasma: Development, Validation, in vivo Pharmacokinetics Study and in vitro Metabolic Stability Research by Zhan R, Liu Y, Wu J, Shen Y, Xu X, Lin G, Chen X

“…Additionally, this method was successful in evaluating pharmacokinetics in rats after an oral dose of 10 mg/kg givinostat. Finally, in vitro results showed that givinostat had a slow intrinsic clearance (CLint) value of 14.92 μL/min/mg protein with a half-life (t1/2) value of 92.87 min.Conclusion: Givinostat was rapidly absorbed and cleared slowly in vivo, and it was confirmed by in vitro experiments. …”
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Verification of the Reliability of an Automated Urine Test Strip Colorimetric Program Using Colorimetric Analysis: Survey Study by Keigo Inagaki, Daisuke Tsuriya, Takuya Hashimoto, Katsumasa Nakamura

“…The results showed a sensitivity of 100% and a specificity of 58.6% in determining albumin in urine, which is important for determining the stage of diabetic nephropathy. Finally, the area under the curve (0.907) derived from the receiver operating characteristic curve was satisfactory. …”
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Whole transcriptome analysis and construction of gene regulatory networks of granulosa cells from patients with polycystic ovary syndrome (PCOS) by Yuan Yuan, Daiterigele, Qian Zhang, Chen Du

“…The target genes were mainly enriched in metabolic pathways such as mitogen-activated protein kinase (MAPK), Wnt, transforming growth factor-beta (TGF-β), and the cell cycle. …”
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A Study on Excavation Characteristics of Tunnel with Upper-Soft Lower-Hard Stratum by Jun Feng, Hui-juan Yang, Yu Zhang

“…After the excavation method was determined, the rule of change in the stress and deformation of the surrounded rock with time in the actual excavation process was analyzed by field monitoring means. Finally, on the basis of the findings in the numerical analysis as well as the field monitoring, the engineering characteristics, such as the stress and deformation of the surrounded rock during the excavation of deep buried tunnels in the upper-soft lower-hard ground, were analyzed. …”
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De Novo Acute Myeloid Leukemia with Combined CBFB-MYH11 and BCR-ABL1 Gene Rearrangements: A Case Report and Review of Literature by Venkata Rakesh Sethapati, Ra’ed Jabr, Leyla Shune, Wissam El Atrouni, Patrick R. Gonzales, Wei Cui, Shivani Golem

“…The detection of t(9;22) led to the addition of daily doses of dasatinib (tyrosine kinase inhibitor) from day 7 onwards. The patient achieved complete remission on day 45. …”
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Soil chemical factors contributing to differences in bacterial communities among tea field soils and their relationships with tea quality by Shuning Zhang, Shuning Zhang, Naoki Yanagisawa, Mio Asahina, Hiroto Yamashita, Hiroto Yamashita, Hiroto Yamashita, Takashi Ikka, Takashi Ikka, Takashi Ikka, Takashi Ikka

“…We conducted pot cultivation of tea plant ‘Yabukita’ to investigate how soil chemical factors affect bacterial communities and their influences on the nutrient status and quality of tea plants, and finally explored the complex relationships between soil bacterial features and tea quality.Results and discussionThe results showed that soil bacterial α-diversity was higher level in soils D and E, with distinct β-diversity patterns separating higher pH soils (D and E) from lower pH soils (A, B, and C). …”
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Early prediction of in-hospital mortality in patients with congestive heart failure in intensive care unit: a retrospective observational cohort study by Tao Huang, Rui Yang, Jun Lyu, Didi Han, Fengshuo Xu, Shuai Zheng, Luming Zhang, Haiyan Yin

“…Discrimination, calibration and clinical validity of the model were evaluated by AUC, calibration curve, Hosmer-Lemeshow χ2 test and decision curve analysis, respectively. Finally, data from 15 503 patients with CHF in the multicentre eICU-CRD were used for external validation of the established nomogram.Results The inclusion criteria were met by 15 983 subjects, whose in-hospital mortality rate was 12.4%. …”
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About One Memorable Date in the History of Spain by G. I. Volkova

“…In 1714 the Catalans, being in the camp of the losers in the War of the Spanish Succession, finally lost any hope to gain independence. 300 years later, nationalists, who are in power now in Catalonia, want to take advantage of that memorable date by organizing a regional referendum in order to choose their own path of development. …”
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Study on Mechanical Performance of Prestressed UHPFRC U-Beam Bridges by Mengying Liu, Eugen Brühwiler, Fengkun Cui, Yue Xu

“…Then, the finite element model considering material nonlinearity and structural ductility is established using Midas FEA software. Finally, the failure mode, failure process, cracking moment, ultimate moment, and strain of the full-scale model are studied. …”
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Mental health risk in human services work across Europe: the predictive role of employment in various sectors by Ágnes Győri, Éva Perpék, Szilvia Ádám

“…Then sociodemographic correlates of occupational mental health risk factors were assessed by means of Pearson's chi-squared test. Finally, correlations were explored between perceived psychosocial risk factors and human vs. non-human services occupations, as well as contextual variables by applying multilevel logistic and multinomial regression analyses.ResultsThe prevalence of mental health risk was 45.1%. …”
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Machine Selection for Inventory Tracking with a Continuous Intuitionistic Fuzzy Approach by Ufuk Cebeci, Ugur Simsir, Onur Dogan

“…The results indicate that Alternative A1 ranked first because of its superior speed and operational efficiency, while Alternative A3 ranked last due to its high initial cost despite being cost-effective. Finally, a sensitivity analysis further examines the impact of varying criteria weights on the alternative rankings. …”
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Identification of CD8+ T Cell-Related Genes: Correlations with Immune Phenotypes and Outcomes of Liver Cancer by Qi Pan, Ying Cheng, Donghua Cheng

“…We then screened the factors in the coexpression module correlated with CD8+ T lymphocyte content greater than 0.4. Finally, the expression levels of these factors were verified at the protein level using immunohistochemistry and single-cell sequencing. …”
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Inducible engineering precursor metabolic flux for synthesizing hyaluronic acid of customized molecular weight in Streptococcus zooepidemicus by Rui Zhao, Jun Li, Yingtian Li, Xujuan Pei, Jingyi Di, Zhoujie Xie, Hao Liu, Weixia Gao

“…In contrast, SE2, utilizing the weaker promoter PR22, synthesized shorter HA with a MW of 1.63 MDa, thereby verifying the hypothesis. Finally, to precisely regulate HA MW according to specific demands, an efficient sucrose-induced expression system was screened and employed to control the transcription level of hasE, obtaining recombinant strain SE3. …”
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Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease by Hua-xiong Zhang, Dilmurat Hamit, Qing Li, Xiao Hu, San-feng Li, Fu Xu, Ming-yuan Wang, Guo-qing Bao, Hong-yan Li

“…Transcription factors (GATA2, POU2F2, NFKB1, etc.) can regulate the expression of biomarkers. Finally, we discovered that all biomarkers could bind to MLT with a strong binding energy. …”
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