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29041
“Urban by nature”: The Sokoto jihadist approach to urban planning
Published 2020-12-01“…The article will thus finally analyze the Sokoto utopia of a completely sedentarized and urbanized Muslim state—a policy propagated both against fellow Fulbe pastoralists and mobile Tuareg allies. …”
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29042
Differential impact of TIM-3 ligands on NK cell function
Published 2025-01-01“…In vitro killing, proliferation and cytokine production assays were implemented to evaluate whether the four TIM-3 ligands differentially modulate TIM-3+ NK cell functions, and whether disruption of TIM-3/ligand interaction can enhance NK cell-mediated antitumor effector mechanisms. Finally, The Cancer Genome Atlas survival analysis and digital spatial profiling were employed to study the potential impact of etiology-associated differences on patients with HNSCC outcomes.Results We demonstrate that TIM-3 is highly prevalent on circulating and tumor-infiltrating NK cells. …”
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29043
Catastrophizing as a Predictor for Pain Perception and Disability Among Patients Undergoing Spinal Cord Stimulation
Published 2025-01-01“…Clinical assessments indicated a pain perception score of 5.6 ± 1.96, Central Sensitization Inventory score of 42.08 ± 18.39, disability score of 37.62 ± 16.13, fear of movement score of 33.11 ± 8.76, and pain catastrophizing score of 28.43 ± 13.14. Finally, pain catastrophizing was significantly associated with pain perception (β = 0.075 and <i>p</i> = 0.008) and disability (β = 0.90 and <i>p</i> < 0.01). …”
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29044
Unveiling Hidden Aspects of Intermediary Organizations in Innovation: A Systematic Review through the Lens of Industry Taxonomy
Published 2024-04-01“…Methods In this study, using the Systematic Literature Review (SLR) method, all related qualitative and quantitative studies, including articles published in journals and conferences until 2022, were examined, and finally 77 articles were found and analyzed in the field of innovative intermediary institutions. …”
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29045
Inflammatory burden index as a prognostic marker in patients with advanced gastric cancer treated with neoadjuvant chemotherapy and immunotherapy
Published 2025-01-01“…Univariate COX regression analysis was used to analyze the independent risk factors of poor tumor regression and overall survival (OS) in this part of patients, and the predictive value of different inflammatory indexes on prognosis was compared by C-index index. Finally, Inflammatory burden index(IBI) was grouped by X-tile software, and Kaplan-Meier method was used to compare the survival difference between groups.ResultsA total of 163 patients were enrolled in this study. …”
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29046
Diversity and Distribution of <i>Phytophthora</i> Species Along an Elevation Gradient in Natural and Semi-Natural Forest Ecosystems in Portugal
Published 2025-01-01“…The results of the pathogenicity tests carried out on 2-year-old chestnut plants confirmed the key role of <i>P. cinnamomi</i> in the recrudescence of chestnut ink disease and the additional risk posed by <i>P. pachypleura</i>, <i>P. plurivora</i>, and <i>P. multivora</i> to Portuguese chestnut forests. Finally, three species, <i>P. citricola</i>, <i>P. hedraiandra</i>, and <i>P. pachypleura</i>, are reported for the first time in the natural ecosystems of Portugal.…”
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29047
Attention to Monkeypox: An Interpretable Monkeypox Detection Technique Using Attention Mechanism
Published 2024-01-01“…To ensure transparency and interpretability, we incorporated Gradient-weighted Class Activation Mapping (Grad-CAM) and Local Interpretable Model-Agnostic Explanations (LIME) to provide clear insights into the model’s diagnostic reasoning. Finally, to comprehensively assess the performance of our model, we employed a range of evaluation metrics, including Cohen’s Kappa, Matthews Correlation Coefficient, and Youden’s J Index, alongside traditional measures like accuracy, F1-score, precision, recall, sensitivity, and specificity. …”
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29048
Expatriation-enhanced competencies: A multiple case study of technology-based entrepreneurs
Published 2023-01-01“…Concerning knowledge and innovative competencies, creativity, learning new techniques and international innovation environment stand at the fore. Finally, international competencies relate to the acceptance of different cultures (multicultural learning and perception of cultural differences), developing a sense of an international community and an international innovation culture. …”
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29049
L’expérience touristique : une expérience des cadres de l’expérience touristique ?
Published 2016-12-01“…Cette dernière acception en particulier permet de mettre en évidence le fait qu’ainsi définie l’expérience touristique est peut-être moins l’expérience de l’autre que l’expérience de la consommation de l’autre ou, pour le dire autrement, le fait que l’expérience touristique n’est peut-être finalement qu’une expérience des cadres de la consommation touristique.…”
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29050
Expression of angiotensin converting enzyme 2 in patients with oral squamous cell carcinoma
Published 2024-06-01“…RNA isolation was performed using the TRIR kit from Invitrogen. cDNA was synthesized from total RNA isolated from tissues using a first-strand synthesis kit. Finally, ACE2 was assayed using an ultrasensitive human-specific ELISA kit. …”
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29051
MT2A promotes angiogenesis in chronically ischemic brains through a copper–mitochondria regulatory mechanism
Published 2025-02-01“…HUVEC activity and mitochondrial structure and function were detected to explore the ability of MT2A to alleviate CPO-induced damage. Finally, a rat model of 2-vessel occlusion plus encephalo-myo-synangiosis (2VO + EMS) with CPO was established to test the proangiogenic effect of MT2A through the copper–mitochondria regulatory mechanism in chronically ischemic brains. …”
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29052
Vaginal colonization, vertical transmission rate, antimicrobial susceptibility profile, and associated factors of potential neonatal pathogens among pregnant women at public health...
Published 2025-02-01“…Logistic regression model was used to identify the associated factors. Finally, variables with p < 0.05 and their 95% confidence interval were considered statistically significant.ResultsA total of 348 pregnant women attending vaginal delivery were included in the study. …”
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29053
Exploring the Determinants of Long-Term Physical Activity Maintainenance from a Maintainers Perspective: What do they say?
Published 2025-01-01“…The interviews were transcribed, anonymized, coded into meaning segments, sorted into themes, and finally grouped into categories. The themes and categories were solely based on the content. …”
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29054
Different cortex activation between young and middle-aged people during different type problem-solving: An EEG&fNIRS study
Published 2025-03-01“…The highest alpha frequency band power for different electrodes was recorded while solving general knowledge questions in the young group and insight questions in the middle-aged group. Finally, the EEG and fNIRS correlation results showed positive correlations between HbO and alpha frequency band power in specific brain regions while solving general knowledge questions, particularly in the middle-aged group.The study reveals age-related differences in behavioral performance, brain activation patterns, and neural correlates during various cognitive tasks, showcasing distinct strengths between middle-aged and young individuals in specific question types.…”
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29055
Color Confinement, Hadron Dynamics, and Hadron Spectroscopy from Light-Front Holography and Superconformal Algebra
Published 2018-01-01“…One obtains empirically viable predictions for spacelike and timelike hadronic form factors, structure functions, distribution amplitudes, and transverse momentum distributions. Finally, I address the interesting question of whether the momentum sum rule is valid for nuclear structure functions.…”
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29056
Chemotherapy-induced cellular senescence promotes stemness of aggressive B-cell non-Hodgkin’s lymphoma via CCR7/ARHGAP18/IKBα signaling activation
Published 2025-01-01“…Transwell assays assessed cell migration and invasion. Finally, inhibitors GS143 and Y27632 were used to examine the effect of IKBα and ARHGAP/RhoA inhibition on B-NHL-TIS.Results Here we identified a distinct group of TIS, composed of memory B-cell population characterized by strong positive expression of CCR7, which was significantly elevated in TIS population compared with normal proliferating and autonomously senescent lymphoma cell populations. …”
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29057
Production technology of poultry sausage-1: the studies on the quality of chemical, microbiological and organoleptic
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29058
Cancer stem cells and tumor-associated macrophages as mates in tumor progression: mechanisms of crosstalk and advanced bioinformatic tools to dissect their phenotypes and interacti...
Published 2025-02-01“…The aggressive behavior of CSCs is guided by several intracellular signaling pathways such as WNT, NF-kappa-B, NOTCH, Hedgehog, JAK-STAT, PI3K/AKT1/MTOR, TGF/SMAD, PPAR and MAPK kinases, as well as extracellular vesicles such as exosomes, and extracellular signaling molecules such as cytokines, chemokines, pro-angiogenetic and growth factors, which finely regulate CSC phenotype. …”
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29059
ALDH1L2 drives HCC progression through TAM polarization
Published 2025-01-01“…In addition, ALDH1L2 knockdown enhances the anti-HCC activity of the tyrosine kinase inhibitor sorafenib. Conclusions: These findings provide the first evidence indicating that ALDH1L2 is directly involved in tumor progression by interacting with tumor-associated macrophages through the Jak2/STAT3 signaling pathway and that ALDH1L2 may be a target molecule for HCC therapy. …”
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29060
Genomic characteristics of ST6115 carbapenem-resistant Klebsiella pneumoniae coharboring blaNDM-1 and blaIMP-4
Published 2025-02-01“…Annotation and analysis of the genome enabled the identification of the plasmid structure and the comparative analysis of the genetic background. Finally, the conjugation transfer experiment was conducted to assess the transferability of the plasmid pHD8428-NDM-IMP.ResultsA comparable phylogenetic analysis revealed that ST6115 HD8428 and the majority of ST17 strains (9/12) were clustered on the same clade, which suggests a close relationship between two ST types. …”
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