Effects of Baicalin on Gout Based on Network Pharmacology, Molecular Docking, and in vitro Experiments by Liu C, Liu W, Lu H, Fan Y, Wang A

“…Subsequently, the key targets were selected to dock with baicalin based on molecular docking. Finally, in vitro experiments were conducted to further validate the predictions.Results: A total of 318 potential targets of baicalin and 752 gout-related targets were screened. …”
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Analyzing the impact of glycemic metabolic status on cardiovascular mortality and all-cause mortality related to the estimated glucose disposal rate: a nationwide cohort study by Shiming He, Shiming He, Shiming He, Chao Wang, Chao Wang, Chao Wang, Xin Huang, Xin Huang, Xin Huang, Guoan Jian, Guoan Jian, Guoan Jian, Zihao Lu, Zihao Lu, Zihao Lu, Kun Jiang, Kun Jiang, Kun Jiang, Guobo Xie, Guotai Sheng, Yang Zou

“…Additionally, Kaplan-Meier curves were used to compare the cumulative incidence of cardiovascular and all-cause mortality across different metabolic statuses. Finally, the predictive value of eGDR for mortality was assessed using receiver operating characteristic curves.ResultsDuring an average follow-up of 115 months, a total of 6,906 (15.01%) participants experienced all-cause mortality, with 1,798 (3.91%) deaths attributed to cardiovascular causes. …”
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Assessing sustainable practices and managerial approaches in the hotel industry: A comparative case study by Jitka Vávrová, Lenka Červová, Blanka Brandová, Jorge Pacheco

“…From a managerial perspective, this study offers a comprehensive overview of hotels’ sustainability practices and serves as a practical list of potential sustainable practices for hotels to consider. Finally, the conclusion provides suggestions for future research that can further advance sustainable practices in the hotel industry. …”
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Rehabilitation Protocol Variability Following Arthroscopic Bankart Repair and Remplissage for Management of Anterior Shoulder Instability: A Systematic Review by Juan B. Villarreal-Espinosa, Michael M. Reinold, Mohammad Khak, Mohammad J. Shariyate, Carol Mita, Jeffrey Kay, Arun J. Ramappa

“…Time to return to sport was also described in 37/41 of the retrieved studies. Finally, only two of the 27 comparative studies tailored their rehabilitation protocol according to the specific procedure performed, underscoring the lack of an individualized approach (i.e. same rehabilitation protocol for different procedures)…”
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Development and Validation of a Nosocomial Infection Nomogram Model in the NICU: A Novel and Nurse-Led Way to Prediction in Preterm Infants by Shang Y, Chen L, Hu X, Zhang K, Cheng Q, Shui X, Deng Z

“…Bootstrap method was used to repeat 1,000 times for internal validation.Results: A total of 892 preterm infants were finally included and a nurse-led predictive model established, which included six variables: skin color changes, respiratory related changes, feeding deterioration, birth weight, number of arterial and venous blood draws, and days of nasogastric tube placement. …”
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RET Inhibitor SPP86 Triggers Apoptosis and Activates the DNA Damage Response Through the Suppression of Autophagy and the PI3K/AKT Signaling Pathway in Melanoma Cells by Zhang Y, Liu H, Wang K, Zheng J, Luan H, Xin M

“…Yuli Zhang,1,2 Haidong Liu,1 Kun Wang,3 Juan Zheng,4 Hong Luan,1 Ming Xin5 1Department of Dermatology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China; 2Department of Endocrinology, The Second Hospital of Shandong University, Jinan, Shandong, People’s Republic of China; 3Department of Endocrinology and Metabology, Liaocheng People’s Hospital, Liaocheng, Liaocheng, Shandong, People’s Republic of China; 4Joint Laboratory for Translational Medicine Research, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China; 5The Key Laboratory of Molecular Pharmacology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of ChinaCorrespondence: Ming Xin, The Key Laboratory of Molecular Pharmacology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China, Email xinming137@163.com Hong Luan, Department of Dermatology, Liaocheng People’s Hospital, Liaocheng, Shandong, People’s Republic of China, Email lcsrmyy@126.comBackground: Melanoma is a highly lethal form of skin cancer, and effective treatment remains a significant challenge. …”
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The effect of environmental awareness as a moderation on determinants of green product purchase intention by A.S. Rama, . Yasri, P. Susanto

“…Therefore, further research should attempt to expand the sample size to include more provinces in Indonesia. Finally, this study used a cross-sectional research design, which gathered data simultaneously.…”
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Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1 by Hong Zhou, Jiaxin Zhou, ShanShan Liu, Jing Niu, Jinghua Pan, Ruiman Li

“…A mouse model of RSA was constructed for confirmation. Finally, we analyzed the correlations between serum hsa-miR-532-3p levels and the clinical features of pregnant women with RSA. …”
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Clinical Application of Laser Walking Stick in Subacute Hemiplegia Walking Training by XIONG Mingyue, ZHAO Yawen, PAN Zhe, TANG Mei, ZHENG Cheng, LUO Yi, TAN Jie

“…Methods were as followed: at first, the patients were told to step forward with affected foot and make the toes as close to the rear red line as possible, and the toes of the healthy side were between the two parallel red lines; secondly, the patients were told to put the affected toes between the parallel red lines, and the healthy toes exceeded the front red line; finally, the patients were instructed to gradually increase the stride length of the affected side to similar to that of the healthy side. …”
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Reloading mechanical characteristics of cemented tailings backfill after dynamic loading action by Xuepeng SONG, Bowen FAN, Shi WANG, Hongwei ZHANG

“…The activity and sparsity of the AE signal initially decrease, then increase, and finally decrease again with the increase in impact amplitude. …”
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Determinants of breast cancer screening among women of reproductive age in sub-Saharan Africa: A multilevel analysis. by Beminate Lemma Seifu, Yohannes Mekuria Negussie, Angwach Abrham Asnake, Fraol Daba Chinkey, Bezawit Melak Fente, Zufan Alamrie Asmare

“…An adjusted prevalence ratio with the corresponding 95% confidence interval was used to measure the strength of the association. Finally, statistical significance was declared at a p-value < 0.05.…”
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Determinants of Preterm Birth among Women Who Gave Birth in Amhara Region Referral Hospitals, Northern Ethiopia, 2018: Institutional Based Case Control Study by Abebayehu Melesew Mekuriyaw, Muhabaw Shumye Mihret, Ayenew Engida Yismaw

“…Variable having    p-value <0.05 in binary logistic regression were the candidate for multivariable analyses. Finally, the statistical significance of the study was claimed based on the Adjusted Odds Ratio (AOR) with 95% Confidence Interval (CI) and its p-value <0.05. …”
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Prevalence of Cryptococcal Antigenemia and Associated Factors among HIV/AIDS Patients at Felege-Hiwot Referral Hospital, Bahir Dar, Northwest Ethiopia by Mohabaw Jemal, Teshiwal Deress, Teshome Belachew, Yesuf Adem

“…A P value <0.05 was considered statistically significant. Finally, data were presented in the form of texts, figures, and tables. …”
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Using XBGoost, an interpretable machine learning model, for diagnosing prostate cancer in patients with PSA < 20 ng/ml based on the PSAMR indicator by Dengke Li, Baoyuan Chang, Qunlian Huang

“…The best-performing model was selected and evaluated through tenfold cross-validation to ensure interpretability. Finally, the performance was assessed using the test set data for validation. …”
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RBMDC-Net: Effective Jaw Cyst Segmentation Network Using Residual Bottleneck and Multiscale Dilated Convolution by Huixia Zheng, Xiaoliang Jiang, Xu Xu, Zhenfei Yuan

“…In addition, we introduce the multi-level feature guidance module (MFGM) to address the issue of semantic dilution that often occurs during the progressive up-sampling. Finally, to evaluate the effectiveness of RBMDC-Net, we developed two image datasets: the first is the original images of jaw cyst collected by Quzhou People&#x2019;s Hospital, and the second is its augmented dataset. …”
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Share Capital Management in the Context of Ensuring Competitive Advantages of the Retail Business Entity by A. S. Dyadin, N. V. Bobro

“…The basis for assessing the structure of capital by the criterion of its effectiveness is the calculation of the effect of financial leverage in previous periods and determining the impact of individual factors (return on assets, weighted average cost of debt, share of debt and equity) on this effect by using the method of chain substitutions regarding the weighted average cost of borrowed capital adjusted for the net operating result of the investment, the value of leased fixed assets, the amount of rent, as well as the share of financial loans, trade payables and long-term credit in the form of leased fixed assets in total borrowed capital. Finally, the target-oriented capital structure is formed during the fifth stage, taking into account the obtained results of optimization according to all the criteria and features of the components of capital and the factors that affect them. …”
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Towards an Automated Design Evaluation Method for Wire Arc Additive Manufacturing by Johannes Pusicha, Henrik Stromberg, Markus Quanz, Armin Lohrengel

“…Additionally, the analogy of Heuvers’ spheres to the MAT helps estimate a limit of <inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><mstyle scriptlevel="0" displaystyle="true"><mfrac><mrow><msub><mi>k</mi><mi>H</mi></msub><mo>−</mo><mn>1</mn></mrow><mrow><msub><mi>k</mi><mi>H</mi></msub><mo>+</mo><mn>1</mn></mrow></mfrac></mstyle></semantics></math></inline-formula> for the mass gradient (<inline-formula><math xmlns="http://www.w3.org/1998/Math/MathML" display="inline"><semantics><msub><mi>k</mi><mi>H</mi></msub></semantics></math></inline-formula>: Heuvers’ factor). Finally, tests on example parts demonstrate the method’s effectiveness in verifying compliance to the specified rules. …”
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Construction and Simulation of Online English Reading Model in Wireless Surface Acoustic Wave Sensor Environment Optimized by Particle Swarm Optimization by Bolan Zhou

“…The research results identified eight cognitive attributes of English reading and successfully generated diagnostic information at the group and individual levels and finally formed graphics and textual diagnostic feedback. …”
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The Explo’Santé mixed methods protocol: an interventional research school health promotion project in France by Matteo Olivo, Adeline Darlington-Bernard, Corélie Salque, Laurie Fraticelli, Emmanuel Ricard, Florence Carrouel, Emily Darlington

“…Discussion Explo’Santé was designed to contribute to school-based health promotion strategies, by including key players, promoting partnerships, targeting multiple levels of impact and effect, and to ensure every step is research-based and informed. Finally, this study aims to identify the elements which would enable Explo’Santé to become a model in France and internationally.…”
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Mechanical properties and damage mechanism of steel fiber reinforced cemented tailings backfill by Yanbi XIONG, Xiaohui LIU, Haiyong CHENG, Shunchuan WU, Jing ZHANG, Weihua LIU, Rujun TUO, Zemin LIU

“…However, exceeding this threshold (25 kg·m−3) negatively impacts the cement matrix structure, increasing porosity and consequently decreasing the mechanical properties of the backfill. Finally, SPSS curve estimation is employed to establish a strength calculation model for backfill at various ages. …”
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