Long-term Cd remediation mechanisms and potential risks in soil with biochar application under dry-wet cycling at different soil moisture levels by Shuang Huang, Zhuowen Meng, Jingwei Wu, Lei Xin, Qin Zhao

“…The results showed that Cd adsorbed by biochar in soils during long-term ageing first underwent rapid adsorption (over 0–5 years of simulated ageing), then equilibrium stabilization (over 5–20 years of simulated ageing), and finally slight re-released (over 20–30 years of simulated ageing). …”
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The protein structurome of Orthornavirae and its dark matter by Pascal Mutz, Antonio Pedro Camargo, Harutyun Sahakyan, Uri Neri, Anamarija Butkovic, Yuri I. Wolf, Mart Krupovic, Valerian V. Dolja, Eugene V. Koonin

“…In addition, we identified a case of exaptation of a cellular nucleoside monophosphate kinase as an RNA-binding protein in several virus families. …”
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Synthesis and antitumor activity of some novel thiophene, pyrimidine, coumarin, pyrazole and pyridine derivatives by Albratty Mohammed, El-Sharkawy Karam Ahmed, Alam Shamsher

“…Also, when compounds 5a,b reacted with either ethyl cyanoacetate or malononitrile, they gave pyridine derivatives (15a-d) through the formation of intermediates (14a-d). Finally, formation of fused pyrimidine derivatives (17a,b) was achieved through the reaction of compounds 5a,b and salicylaldehyde applying two different pathways. …”
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Overexpressing the ClpC AAA+ unfoldase accelerates developmental cycle progression in Chlamydia trachomatis by Aaron A. Jensen, Saba Firdous, Lei Lei, Derek J. Fisher, Scot P. Ouellette

“…By analyzing the global transcriptional response to ClpC overexpression using RNA sequencing, we observed a shift to earlier expression of canonical late developmental cycle genes and other EB-associated genes. Finally, we directly linked overexpression of ClpC with earlier production of infectious chlamydiae. …”
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Problems and Barriers Related to the Use of AI-Based Clinical Decision Support Systems: Interview Study by Godwin Denk Giebel, Pascal Raszke, Hartmuth Nowak, Lars Palmowski, Michael Adamzik, Philipp Heinz, Marianne Tokic, Nina Timmesfeld, Frank Brunkhorst, Jürgen Wasem, Nikola Blase

“…Initially, the problems were separated into “general,” “development,” and “clinical use.” Finally, a workshop within the project consortium served to systematize the identified problems. …”
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Identification of a novel heterozygous GPD1 missense variant in a Chinese adult patient with recurrent HTG-AP consuming a high-fat diet and heavy smoking by Xiao-Yao Li, Bei-Yuan Zhang, Xin-Ran Liang, Yan-Yu Han, Min-Hua Cheng, Mei Wei, Ke Cao, Xian-Cheng Chen, Ming Chen, Jian-Feng Duan, Wen-Kui Yu

“…A biogenic analysis was performed to study the population frequency, conservation, and electric potential diagram of the new variant p.K327N. Finally, the previously reported GPD1 variants were sorted and their phenotypic relationships were compared. …”
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Length of stay in the pediatrics emergency department and associated factors among pediatrics patients in Eastern Ethiopia public hospital, Ethiopia 2022. by Netsanet Melkamu, Amelmasin Faris, Muluken Yigezu, Mickiale Hailu, Anteneh Atle, Manaye Kasahun, Mohammed Kebede, Tsegasew Embiale, Tsinukal Tesfay, Sewmehone Amsalu, Yakob Tadese, Bruck Tesfaye, Gebrehiwot Berie

“…After data is collected and cleaned, entered using Epi data version 4.6 and then exported to Stata version 14.1 for analysis. Finally, an AOR with a 95% CI was computed, and variables with a P-value < 0.05 in the multivariable analysis were taken as significant factors for prolonged length of stay.…”
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Sylvain Sangla, Politique et espace chez Henri Lefebvre by Sylvain Sangla

“…Les acquis de nos recherches consistent finalement dans : la vérification de l’importance de l’œuvre lefebvrienne (notamment en ce qui concerne l’espace, la ville et l’urbain) ; l’examen du marxisme anarchisant lefebvrien, qui permet la compréhension des contradictions actuelles et des révolutions possibles ; la précision du lien consubstantiel existant entre les analyses lefebvriennes de l’espace et l’autogestion ; la vérification d’une convergence entre la pensée de Lefebvre et celle de Deleuze.…”
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Developing a decision support tool to predict delayed discharge from hospitals using machine learning by Mahsa Pahlevani, Enayat Rajabi, Majid Taghavi, Peter VanBerkel

“…The ALC guideline groups patients first by diagnosis, then by age, and finally by entry code, categorizing prediction outcomes into three probability ranges: below 30%, 30-70%, and above 70%. …”
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Clinical Predictors of Aspirin Resistance in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis by Fan Zhang, Hongyan Zheng

“…Results: In total, 10 publications were finally included in our study (n = 2113 patients). …”
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Artificial Neural Network and Response Surface Methodology-Driven Optimization of Cu–Al₂O₃/Water Hybrid Nanofluid Flow in a Wavy Enclosure with Inclined Perio... by Tarikul Islam, Sílvio Gama, Marco Martins Afonso

“…Furthermore, the ANN model demonstrates high accuracy with a mean squared error (MSE) of 0.00018, making it a strong alternative to RSM analysis. Finally, this study focuses on the interaction between the hybrid nanofluid, a wavy geometry, and MHD effects, which can optimize heat transfer and contribute to energy-efficient cooling or heating technologies.…”
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Mechanism of melanoma suppression by Prosopis juliflora derived alkaloids: Apoptosis induction and signaling pathway inhibition by Jasoda Choudhari, Snehal K. Nimal, Shridhar Chougule, Trupti Shinde, N.R. Dhatrak, Gopal C. Kundu, Rajesh N. Gacche

“…Notably, PJLME-AF inhibited spheroid formation and reduced PD-L1 expression. Finally, anti-tumor activity of PJLME-AF was further confirmed in a in-vivo mice model. …”
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A predictive risk‐scoring model for survival prognosis of multiple myeloma based on gain/amplification of 1q21: Experience in a tertiary hospital in South‐Western China by Yanqiu Xiong, Shanshan Liang, Wenjiao Tang, Li Zhang, Yuhuan Zheng, Ling Pan, Ting Niu

“…The model's discriminative ability was evaluated using the AUC in both the training and validation sets. Finally, we compared the performance of the +1q21‐involved risk with the established R‐ISS and R2‐ISS models. …”
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A Novel Variant Of Regenerating Iα Gene (REG) In Type II Diabetics Among Pakistani Targeted Population by Sadaf Saleem, Saeeda Baig, Sadia Farrukh, Mazhar Shafiq

“…Results: Blood samples were drawn from 90 finalized patients, including 70 diabetics and 20 controls with an M: F ratio of 12:8. …”
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Anticancer effects of ABTL0812, a clinical stage drug inducer of autophagy-mediated cancer cell death, in glioblastoma models by Andrea Mancini, Alessandro Colapietro, Loredana Cristiano, Alessandra Rossetti, Vincenzo Mattei, Giovanni Luca Gravina, Giovanni Luca Gravina, Héctor Perez-Montoyo, Marc Yeste-Velasco, Jose Alfon, Carles Domenech, Claudio Festuccia

“…Furthermore, the histological analysis of tumors indicated that ABTL0812 decreases angiogenesis. Finally, we investigated the combination of ABTL0812 with the standard of care treatments for GBM radiotherapy and temozolomide in an orthotopic model, detecting that ABTL0812 potentiates the efficacy of both treatments and that the strongest effect is obtained with the triple combination of ABTL0812+radiotherapy+temozolomide.ConclusionsOverall, the present study demonstrated the anticancer efficacy of ABTL0812 as single agent and in combination with the GBM standard of care treatments in models of glioblastoma and supports the clinical investigation of ABTL0812 as a potential novel therapy for this aggressive brain tumor type.…”
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Diagnosis of Schizophrenia and Its Subtypes Using MRI and Machine Learning by Hosna Tavakoli, Reza Rostami, Reza Shalbaf, Mohammad‐Reza Nazem‐Zadeh

“…Moreover, a validation phase involved employing the model on a dataset domestically acquired using the same imaging assessments (N = 13). Finally, we explored the correlation between neuroimaging features and behavioral assessments. …”
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Vehicle-Mounted Photovoltaic System Energy Management in Intelligent Transportation Systems: A Maximum Power Point Tracking Control by Jingao Wang, Qifei Liu, Silan Jing

“…Based on this, it does not need to cause multiple interference to the circuit, and the tracking efficiency is high. Finally, the relative experimental results are provided to verify the performance of the proposed method.…”
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Antifungal activity and mechanism of Phoebe bournei wood essential oil against two dermatophytes by Yan Yang, Qinglin Sun, Yuting Zhang, Junhua Huang, Wenjun Ma, Qi Yang, Zaikang Tong, Junhong Zhang

“…ROS and MMP probe detection of intracellular ROS and MMP change. Finally, WGCNA analysis was used to identify and verify the key genes.ResultsWe found that the main components of PWEO are monoterpenes and sesquiterpenoids. …”
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Evaluation and comparison of portfolios formed by strategies through PE, PEG, PERG-SD, and PERG-Beta in the Tehran stock exchange by Hossein Eslami, Seyed Mohammad Moshashaei, Farzad Rahimzadeh

“…At the end of each season, the return and systematic risk of each category of portfolios were calculated. Finally, based on the risk and return of each portfolio, research hypotheses were tested using statistical tests (Wilcoxon and Friedman) and SPSS software.Findings: The results showed that the return of portfolios formed by low coefficients (LOW) is higher than the return of portfolios formed by high coefficients (HIGH) and the TEDPX index in all four strategies: PE, PEG, PERG-SD, and PERG-Beta. …”
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Prevalence of Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae in Ethiopia: A Systematic Review and Meta-Analysis by Teklehaimanot Kiros, Lema Workineh, Tegenaw Tiruneh, Tahir Eyayu, Shewaneh Damtie, Debaka Belete

“…Estimation of outcome measures at 95% confidence interval was performed using Der-Simonian-Laird’s random-effects model. Finally, results were presented via text, figures, and tables. …”
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