Revisiting Cosa (Ansedonia, Italy): contributions of SAR-X images from the PAZ satellite to non-invasive archaeological prospecting by José Ignacio Fiz Fernández, Pere Manel Martín Serrano, Maria Mercè Grau Salvat, Antoni Cartes Reverté

“…It can be confirmed that the multi-temporal treatment of SAR PAZ images provides better results than an individualised analysis of the image. Finally, it is of great interest to verify the results of studies using new technologies, where it was previously possible to resort only to prospecting on the ground and to analogical aerial photography in black and white. …”
Get full text

CT45A1‐mediated MLC2 (MYL9) phosphorylation promotes natural killer cell resistance and outer cell fate in a cell‐in‐cell structure, potentiating the progression of microsatellite... by Hao‐Wei Teng, Hsiang‐Yueh Huang, Chun‐Chi Lin, Yuh‐Ching Twu, Wen‐Hao Yang, Wen‐Chun Lin, Hsin‐Yi Lan, Yen‐Yu Lin, Wei‐Lun Hwang

“…Inactivating RHO‐ROCK/MLCK‐MLC2 signaling with small‐molecule inhibitors or short‐hairpin RNAs (shRNAs) targeting myosin light chain kinase (MYLK) abolished NK cell resistance and reduced the outer cell fate of CT45A1‐expressing MSI‐H CRC cells. …”
Get full text

Association of Matrix Metalloproteinase 9 (MMP-9) Polymorphisms with Asthma Risk: A Meta-Analysis by Fenfang Zou, Jianpeng Zhang, Guoan Xiang, Hongbin Jiao, Hongmei Gao

“…Seven studies with 1592 asthma patients and 1987 controls were finally identified. Overall, we found no significant association between −1562 C > T, rs3918242 polymorphism, and asthma susceptibility in any of the genetic model comparisons. …”
Get full text

Attitudes of Turkish academics towards the effects of digital journalism on shaping the political image by Omar Suleiman Saleh Malkawi

“…The statement with the highest average behavioral influences was “It enabled me to follow the speeches and reactions of heads of state in all activities and areas” (AVT = 2.40). Finally, a low positive correlation (0.307**) was found between the effects of the general political mental image and the image of the electoral candidate (p < 0.05), in addition to a low positive correlation between the digital journalism arts and the elements of the general political mental image, where the value of (p < 0.05) was found.…”
Get full text

A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer by Chenxi Lv, Tianwei Chen, Jiangtao Li, Yuqiang Shan, Hong Zhou

“…Single-cell analysis was conducted to investigate cellular interactions associated with the immune-determinant gene module. Finally, immunofluorescence staining for CD8, CD45, and CXCR4 was performed on human GC tissue samples. …”
Get full text

An Effective Dataset Preprocessing Method in Tilted Gear Defects Target Detection by Lifen Tu, Qi Peng, Aiqun Zhang, Xiao Yang, Jiaqi Wang

“…Subsequently, the rotated data are utilized to train the defect detection model. Finally, the test set is subjected to the same image rotation method as the first step, resulting in the generation of high-precision defect detection results, which are then input into the defect detection model. …”
Get full text

Blockchain technology adoption strategies for the shipping costs bearer in the fresh product supply chain by Weisi Zhang, Lin Wu, Lulu Ji

“…Specifically, when the R&D cost coefficient of CER is high, regardless of blockchain adoption, the supplier bearing the shipping costs maximizes the overall profit of the supply chain. Finally, concerning whether the bearer should invest in blockchain technology, when the R&D cost coefficient of CER is low and consumer low-carbon preferences are high, adopting blockchain technology leads to Pareto optimal profits for both the supplier and the retailer, regardless of who bears the shipping costs. …”
Get full text

Optimal dietary vitamin E level facilitates ovarian development of female largemouth bass (Micropterus salmoides) broodstock by Qiuyu Gao, Qiao Feng, Dong Zhou, Zhili Ding, Changle Qi, Youqin Kong, Qiyou Xu

“…Dietary vitamin E supplementation significantly upregulated the expression of genes involving vitamin E transfer, ovarian development, and hormone, including alpha-tocopherol transfer protein, luteinizing hormone, follicle-stimulating hormone, vitellogenin receptor (vgr), vitellogenin (vg), 17-beta-hydroxysteroid dehydrogenase (17β-hsd), cyclin-dependent kinase 2 (cdk2), and cytochrome P450 family 17 (cyp-17), with the highest expression levels detected in the 209.31 mg/kg group (P < 0.05). …”
Get full text

Curative Effect of AD-MSCs against Cisplatin-Induced Hepatotoxicity in Rats is Potentiated by Azilsartan: Targeting Oxidative Stress, MAPK, and Apoptosis Signaling Pathways by Amany Abdlrehim Bekhit, Olivia N. Beshay, Michael A. Fawzy, Sara Mohamed Naguib Abdel-Hafez, Gaber El-Saber Batiha, Farid S. Ataya, Moustafa Fathy

“…In conclusion, the present findings demonstrated that AZIL improves the hepatoprotective potential of AD-MSCs against CISP-induced hepatotoxicity by modulating oxidative stress, mitogen-activated protein kinase, and apoptotic pathways.…”
Get full text

Design and Performance of Ultrathin Overlay Epoxy-Rubber Concrete by Qi Huang, Fei Chen

“…Then, the amount of epoxy resin binder was further determined based on the porosity and antistripping performance of the epoxy-rubber concrete. Finally, the mechanical properties, road performance, and functions of epoxy-rubber concrete were comprehensively considered to determine the optimum rubber power replacement rate obtaining the composition design of epoxy-rubber concrete. …”
Get full text

Relationship between upper extremity fat mass and race time in triathlete by Ebru Cetın, Ulviye Bılgın, Mergul Colak, İmdat Yarım, Halil Taskın

“…At 40 ° C air temperature, athletes firstly swam for 1.5 km, which was followed by cycling on 40 km track and finally 10 kilometers track run. SPSS 16.0 statistical software was utilized for data calculation and evaluation. …”
Get full text

Efficient Method for Robust Backdoor Detection and Removal in Feature Space Using Clean Data by Donik Vrsnak, Marko Subasic, Sven Loncaric

“…Secondly, it reduces the memory footprint and the computation time by at least an order of magnitude compared to other methods, which allows FEAT-IN to be used practically in real-world scenarios. Finally, it is not constrained to only computer vision tasks, as this assumption holds for feature spaces of different problems, which is demonstrated by applying it without any change to semantic analysis on the SST-2 dataset.…”
Get full text

The Potential Role of sPD-L1 as a Predictive Biomarker in EGFR-Positive Non-Small-Cell Lung Cancer by Vesna Ćeriman Krstić, Dragana Jovanović, Natalija Samardžić, Milija Gajić, Jelena Kotur Stevuljević, Aleksandra Klisic, Ivan Soldatović, Damir Radončić, Marina Roksandić Milenković, Biljana Šeha, Nikola Čolić, Katarina Lukić, Milan Savić

“…Materials and Methods: Blood samples from 35 patients with EGFR-mutated (EGFRmut) adenocarcinoma who achieved disease control with EGFR tyrosine kinase inhibitor (EGFR TKI) therapy were collected for sPD-L1 analysis. …”
Get full text

Characterization of the genomic landscape of canine diffuse large B-cell lymphoma reveals recurrent H3K27M mutations linked to progression-free survival by Anna Darlene van der Heiden, Raphaela Pensch, Sophie Agger, Heather L. Gardner, William Hendricks, Victoria Zismann, Shukmei Wong, Natalia Briones, Bryce Turner, Karin Forsberg-Nilsson, Cheryl London, Kerstin Lindblad-Toh, Maja Louise Arendt

“…In particular, we identified hotspot mutations in two histone genes, H3C8, and LOC119877878, resulting in H3K27M alterations predicted to dysregulate gene expression. Finally, a survival analysis revealed that H3K27M mutations in H3C8 were associated with increased hazard ratios for progression-free survival. …”
Get full text

An Analysis of the Effectiveness and Safety of Upadacitinib in the Treatment of Inflammatory Bowel Disease: A Multicenter Real-World Study by Hongzhen Wu, Tingting Xie, Qiao Yu, Tao Su, Min Zhang, Luying Wu, Xiaoling Wang, Xiang Peng, Min Zhi, Jiayin Yao

“…Upadacitinib, a Janus kinase 1 (JAK1) inhibitor, has shown effectiveness in trials for Crohn’s disease (CD) and ulcerative colitis (UC). …”
Get full text

Medication related osteonecrosis (MRONJ) in the management of CTIBL in breast and prostate cancer patients. Joint report by SIPMO AND SIOMMMS by Francesco Bertoldo, Cristina Eller-Vainicher, Vittorio Fusco, Rodolfo Mauceri, Jessica Pepe, Alberto Bedogni, Andrea Palermo, Umberto Romeo, Giuseppe Guglielmi, Giuseppina Campisi

“…., CTIBL and its management, pharmacology and pharmacodynamics of BMAs, definition and diagnosis of MRONJ), developed a joint report on the following five issues: a) prevention and dental management in cancer patients candidates to LD-BMAs, or under LD-BMAs; b) prophylactic drug holiday; c) MRONJ treatment; d) LD-BMAs therapeutic drug holiday; and e) restart of LD-BMA treatment after successful healing of MRONJ.Finally, ten key questions with answers were prepared and placed at the end of the document. …”
Get full text

Embryonic heat conditioning induces paternal heredity of immunological cross- tolerance: coordinative role of CpG DNA methylation and miR-200a regulation by Padma Malini Ravi, Tatiana Kisliouk, Shelly Druyan, Amit Haron, Mark A. Cline, Elizabeth R. Gilbert, Noam Meiri

“…Additionally, analysis of sperm methylation patterns in EHC mature chicks led to identification of genes associated with neuronal development and immune response, indicating potential neural network reorganization. Finally, miR-200a emerges as a regulator potentially involved in mediating the cross-tolerance effect.…”
Get full text

Effect of trilaciclib administered before chemotherapy in patients with extensive-stage small-cell lung cancer: A pooled analysis of four randomized studies by Ying Liu, Lin Wu, Dingzhi Huang, Qiming Wang, Chen Yang, Li Zhou, Shuguang Sun, Xiaomei Jiang, Ying Cheng

“…Background: Trilaciclib is a transient cyclin-dependent kinase 4/6 (CDK4/6) inhibitor that reduces the incidence of chemotherapy-induced myelosuppression (CIM). …”
Get full text

Goose astrovirus induces apoptosis and endoplasmic reticulum stress in gosling hepatocytes by Zhihua Lu, Haiqin Li, Xiaona Gao, Duanfeng Fu, Haoyu Huang, Cheng Huang, Meiqin Wu, Xiaoquan Guo

“…RT-qPCR and Western blot analyses indicated that GoAstV infection enhanced the expression of ER Ca2+ release channels (IP3R and RYR) and calmodulin-dependent protein kinase II (CaMKII), while decreasing the expression of ER Ca2+ uptake channels (SERCA). …”
Get full text

Investigation of the Effects and Degradation Mechanism of Low-oxygen on the Stability of Blueberry Anthocyanins in Juice Simulation system by Zhouyang SHENG, Gengsheng XIAO, Lijuan ZHANG, Yujuan XU, Jijun WU, Yuanshan YU, Tenggen HU, Bo ZOU

“…The effects of different metal ions, ascorbic acid, and phenolic acids under low oxygen and conventional conditions on anthocyanins were compared. Finally, high-performance liquid chromatography-triple quadrupole mass spectrometry tandem analysis was used to detect the degradation products of anthocyanins.…”
Get full text