How efficient are specialized public health services in China? A data envelopment analysis and geographically weighted regression approach by Qian Bai, Qian Bai, Lieyu Huang, Yan Guo, Xin Xu, Zhouyixin Zhang, Yuan Wang, Hao Chen, Ying Bian, Ying Bian

“…Meanwhile, in the context of restricted public health resources, how to efficiently utilize these resources becomes a paramount concern.ObjectiveThis study aimed to evaluate the technical efficiency of specialized public health facilities, the major providers of public health services in China, then discuss its temporal and spatial distribution characteristics and finally investigate its influencing factors.MethodsThe super slacks-based measure data envelopment model was constructed to calculate the efficiency of specialized public health facilities of 31 provinces from 2017 to 2019. …”
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From fear to food: predation risk shapes deer behaviour, their resources and forest vegetation by Martin, Jean-Louis, Chamaillé-Jammes, Simon, Salomon, Anne, Gomez Pourroy, Devana Veronica, Schlaeflin, Mathilde, Le Saout, Soizic, Lucas, Annick, Bentaleb, Ilham, Chollet, Simon, Pattison, Jake, Martin-Blangy, Soline, Gaston, Anthony James

“…This contrasted with the wary behaviour observed in the local deer born after the culls. Finally, deer in populations exposed to risk from hunters and/or predators were less likely to forage in the intertidal, although this trend might be, to some extent, affected by resources in the understory. …”
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Comparison of air-liquid interface transwell and airway organoid models for human respiratory virus infection studies by Camilla T. Ekanger, Camilla T. Ekanger, Camilla T. Ekanger, Nilima Dinesh Kumar, Rosanne W. Koutstaal, Fan Zhou, Martin Beukema, Joanna Waldock, Simon P. Jochems, Noa Mulder, Cécile A. C. M. van Els, Cécile A. C. M. van Els, Othmar G. Engelhardt, Nathalie Mantel, Kevin P. Buno, Karl Albert Brokstad, Karl Albert Brokstad, Agnete S. T. Engelsen, Agnete S. T. Engelsen, Rebecca J. Cox, Rebecca J. Cox, Barbro N. Melgert, Barbro N. Melgert, Anke L. W. Huckriede, Puck B. van Kasteren

“…Following infection, a reproducible antiviral cytokine response, including a consistent increase in CXCL10, IL-6, IFN-λ1, IFN-λ2/3, and IFN-β, was detected across all models. Finally, neutralization was assessed by pre-incubation of virus with human serum. …”
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Energy-Saving Metro Train Timetable Optimization Method Based on a Dynamic Passenger Flow Distribution by Jingshuang Li, Fuquan Pan, Hailiang Tang, Sen Tong, Lixia Zhang, Xinguang Li, Xiaoxia Yang

“…The PSO-GA structure has PSO as the main body and integrates the chromosome crossover and mutation operations of the GA into the iterative process to improve the search efficiency of the algorithm. Finally, the proposed method and model are tested based on the actual data of a metro line in Qingdao, China. …”
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The ground beneath our feet: A critical reflection on 135 years of landscape evolution models for southern Africa by Rivoningo Khosa, Vela Mbele, Kelly Kirsten, Robyn Pickering

“…As scientists, we should also re-evaluate the terminology used in scientific dialogue to ensure it accurately reflects evolving perspectives. Finally, while the use of qualitative and quantitative methods have their unique benefits, we consider the application of more quantitative methods of landscape dating to test the existing models and build new, more complex ones. …”
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Predicting recurrence of non-muscle invasive bladder urothelial carcinoma: predictive value of the optimal cut-off value of Ki67 by Rende Peng, Yaoyu Zhang, Mingzhu Jia, Xinping Yi, Xiaoyao Yi, Shadan Li, Jiangchuan Pi, Wenjun Meng

“…ObjectiveTo investigate the optimal cut-off value of immunohistochemical marker Ki67 as a prognostic factor to predict the recurrence of non-muscle invasive bladder urothelial carcinoma (NMIBUC).MethodsA total of 331 patients diagnosed with NMIBUC who underwent surgery in the Yongchuan Hospital and the Second Affiliated Hospital of Chongqing Medical University from January 2012 to January 2020 were finally included in this study. The optimal cut-off value of Ki67 for predicting recurrence of NMIBUC was calculated by ROC curve and Youden index. …”
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A General Framework for Closed Loop Negative Feedback Multivariable Physiological Control Systems: Existence, Uniqueness, and Stability of Homeostatic Equilibrium Points by Anna Procopio, Annarita Tedesco, Fabrizio Lo Regio, Giuseppe Cesarelli, Leandro Donisi, Carlo Ricciardi, Alessio Merola, Alfonso Maria Ponsiglione, Maria Romano, Francesco Montefusco, Carlo Cosentino, Francesco Amato

“…The development of such a general model has at least three important repercussions: the first concerns the possibility of better understanding the basic mechanisms common to many physiological systems; the second is to develop a common theoretical framework to enable effective approaches to the analysis and design of synthetic biological control systems; finally, the investigation of the structural properties of the model in a general context, allows a guided and simplified application to specific cases. …”
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Development and Validation of a Nomogram for Predicting Long-Term Net Adverse Clinical Events in High Bleeding Risk Patients Undergoing Percutaneous Coronary Intervention by Junyan Zhang, Zhongxiu Chen, Ran Liu, Yuxiao Li, Hongsen Zhao, Yanning Li, Minggang Zhou, Hua Wang, Chen Li, Li Rao, Yong He

“…These were then utilized to construct a prognostic prediction nomogram, including chronic kidney disease, left main stem lesion, multivessel disease, triglycerides (TG), and creatine kinase-myocardial band (CK-MB). The nomogram exhibited strong predictive ability (the area under the curve (AUC) to predict 1-year NACE-free survival was 0.728), displaying favorable levels of accuracy, discrimination, and clinical usefulness in the internal validation cohort. …”
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NOX4 modulates breast cancer progression through cancer cell metabolic reprogramming and CD8+ T cell antitumor activity by Yingying Xiong, Yiming Weng, Shan Zhu, Jian Qin, Jia Feng, Xiaopeng Jing, Chao Luo, Wei Gong, Rui Sun, Min Peng

“…Flow cytometry characterized tumor-infiltrating immune cells. Finally, NOX4-overexpressing cells were tested for survival benefit and response to dual-checkpoint immunotherapy (anti-PD-1/anti-CTLA-4).ResultsNOX4 deletion accelerated tumor growth in vivo and enhanced proliferation, colony formation, and migratory capacity in vitro. …”
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Du nomadisme à la sédentarisation by Aimé Landry Dongmo, Patrice Djamen, Éric Vall, Koussou Mian-Oudanang, Doubangolo Coulibaly, Jean Lossouarn

“…Livestock breeding systems, crop-livestock relationships and livestock product industries are studied to highlight the modalities of farming practices, stakeholder logics and their effects on the sustainability of natural resources, economic profitability and social equity. Finally, prospects are put forward to support the sustainable development of pastoral faming systems.…”
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Self /other recognition and distinction in adolescents with anorexia nervosa: A pilot study using a double mirror paradigm. by Nathalie Lavenne-Collot, Emilie Maubant, Stéphanie Déroulez, Guillaume Bronsard, Moritz Wehrmann, Michel Botbol, Alain Berthoz

“…Furthermore, in contrast with that of HCs, the critical threshold for switching between self and other varied with the direction of morphing in anorexia nervosa participants. Finally, when participants with anorexia were seated in a chair with a backrest and footrest strengthening the median axis of their body, the self-recognition threshold (M1) increased significantly, approaching that of controls.…”
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Book history's recent methodological trend: national and intemational outlines by Jyrki Hakapää

“…Secondly, researchers should seek alternative defining frameworks: studies focusing on linguistic, social, or gender borders, rather than a national approach, would offer further insights. Finally, specific methodologies have been created for international history studies; comparative studies, studies on cultural transfer, and entangled histories all reveal different aspects of examined societies and individuals. …”
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Rural-Urban Determinants of Receiving Skilled Birth Attendants among Women in Bangladesh: Evidence from National Survey 2017-18 by Sohani Afroja, Abu Saleh Muhammad Nasim, Md. Salauddin Khan, Mohammad Alamgir Kabir

“…To identify the association, we performed the chi-square test. Finally, multiple logistic regression was used to analyse the factors associated with SBAs and determine the degree of SBAs disparity between urban and rural areas. …”
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Metabolic profiling of Perilla leaves of different colors: insights into metabolite variation and bioactive compound distribution by Senouwa Segla Koffi Dossou, Qianchun Deng, Feng Li, Lei Wang, Nanjun Jiang, Habtamu Kefale, Rong Zhou, Donghua Li, Meilian Tan, Linhai Wang

“…Glycosylated cyanidins and delphinidins were identified as the key compounds responsible for the purple coloration of leaves. Finally, we found that the variation in glutamate metabolism may be one of the main contributors for variation in metabolite profiles and biological attributes of Perilla leaves of different colors. …”
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A lightweight wheat ear counting model in UAV images based on improved YOLOv8 by Ruofan Li, Xiaohua Sun, Kun Yang, Zhenxue He, Zhenxue He, Xinxin Wang, Xinxin Wang, Chao Wang, Chao Wang, Bin Wang, Fushun Wang, Fushun Wang, Hongquan Liu, Hongquan Liu

“…Additionally, a lightweight dynamic upsampler, Dynamic Sample (DySample), is introduced to decrease computational complexity of the upsampling process by dynamically adjusting interpolation positions. Finally, the lightweight module Spatial Context-Aware Module (SCAM) is utilized to accurately map the connection between small targets and global features, enhancing the discrimination of small targets from the background. …”
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Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish by Sunil Sharma, Alfredo Rojas, Abhishek Gour, Rosemaria Serradimigni, Connor Leong, Abhisheak Sharma, Subham Dasgupta

“…We then assessed global DNA methylation using a combination of whole-mount immunohistochemistry and ELISA for 5-methylcytosine (5-mC) and showed significant IPP-induced hypermethylation within whole embryo in situ. Finally, we focused on eye and brains as targets. …”
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Identification and validation of key autophagy-related genes in lupus nephritis by bioinformatics and machine learning. by Su Zhang, Weitao Hu, Yelin Tang, Xiaoqing Chen

“…Additionally, the association between key genes and kidney diseases was predicted. Finally, key genes expression in kidney was verified by clinical samples and animal experiments.…”
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Assessment of toxic response of Lactuca sativa to compost extracted from agri-food waste by Diego Andr´es Zapata-Gonz´alez, Juan Manuel Trujillo-Gonz´alez, Marco Aurelio Torres-Mora, Daniel Gonz´alez-Santamaria, Raimundo Jim´enez-Ballesta

“…Method: We set up a mini composting pilot where raw materials were classified, chopped into bits, and finally mixed. They include residues of Solanum tuberosum (potatoes), Zea mays (corn), Musa Paradisiaca (bananas), Allium cepa (onions), Lactuca sativa (lettuce), Daucus carota (carrots), Solanum lycopersicum (tomatoes), as well as fruits such as Passiflora edulis (passion fruit), Carica papaya (papaya). …”
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Variative Components of the University Course of Mathematical Analysis: The Experience of Introduction into the Practice of Teaching by S. I. Кalinin, L. V. Pankratova

“…Secondly, the variable content of education offers the possibility to systematically rethink and rapidly revise educational material, taking into account new scientific facts and discoveries. Finally, it can develop cognitive autonomy of junior students, encouraging them to carry out regular and informal research activities. …”
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Unlocking the Potential of Receptor-Based Approaches in Diabetes Treatment by Mohsina Patwekar, Faheem Patwekar, J. Pavan Kumar, P. Dharani Prasad, Nazia Malik, A. Venkata Badarinath, Prashanth Parupathi, Konatham Teja Kumar Reddy, Selvaraja Elumalai, Zainul Abedeen Ab Samad

“…Additionally, G-protein-coupled receptor (GPCR) agonists and adenosine monophosphate-activated protein kinase (AMPK) activators are emerging as potential medicines to improve insulin sensitivity, glucose uptake, and insulin signaling pathways. …”
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