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28581
L’anxiété technocratique en France : les romans du Fleuve Noir « Anticipation », 1951-1960
Published 2019-06-01“…Bruss have problems with the inequality and oppressiveness of any technocratic scheme of things ; and Peter Randa suggests that virtually any form of social organization is inimical to the radical kind of individualism that he favors. Finally, in a class by himself and counterpointing Richard-Bessière, we have Gérard Klein. …”
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28582
Attention-enhanced optimized deep ensemble network for effective facial emotion recognition
Published 2025-04-01“…Subsequently, the channel attention module (CAM) and spatial attention module (SAM) are sequentially incorporated in the framework for dominant feature selection. Finally, we integrated fully connected (FC) layers to accurately classify facial emotions (anger, disgust, fear, happy, neutral, sad, and surprise). …”
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28583
PB2 and PA mutations contribute to the pathogenicity of mouse-adapted pdmH1N1-Venus reporter influenza A virus in a mammalian model
Published 2025-01-01“…After passaging the recombinant influenza virus carrying Venus from lung to lung in mice, we found that virulence of the passaged pdmH1N1 CA04-Venus significantly increased and was lethal to the mice. We finally isolated one mouse-adapted pdmH1N1 CA04-Venus with bigger plaques expressing the amount of Venus proteins by using the ninth passage lung homogenate with plague purification. …”
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28584
Experimental Investigations of Offshore Sand Production Monitoring Based on the Analysis of Vibration in Response to Weak Shocks
Published 2021-01-01“…Based on this knowledge, a real-time calculation model of sand production in offshore oil wells is constructed, and the effectiveness of this model is verified. Finally, a field test is carried out with a self-developed sand production signal dynamic time-frequency response software system on 4 wells of an oil production platform in the Bohai Sea. …”
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28585
Spectroscopic analysis (UV-VIS-NIR) for predictive modeling of macro and micronutrients in grapevine leaves
Published 2025-03-01“…Assessing nutrient concentrations in grapevines is crucial not only for the overall physiology of the plant but also for the quality of the resulting wine. Accurate determinations are also relevant for enhancing nutrient use efficiency and formulating fertilizer recommendations. …”
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28586
Confounding Risk Factors in Developing Type 1 Diabetes Mellitus among Children and Adolescents at Sulaimani Chronic Diabetes Health Center
Published 2021-07-01“…Residency and Family history of autoimmune disease were ranked in the fifth line of factor, finally the weakest factor is nationality by total variance of 8.552%. …”
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28587
Electronic media use and sleep in toddlerhood and preschool age
Published 2018-03-01“…Children who were sleeping shorter than 8 hours at night were using computers longer during the week and on weekends, they also spent more time on other screens during the weekends. Finally, the longer over all screen time was prominent in the group of children who had the highest scores of sleep problems. …”
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28588
Identification of lethality-related m7G methylation modification patterns and the regulatory features of immune microenvironment in sepsis
Published 2025-01-01“…Subsequently, 1707 DEGs were identified between the two subtypes, which were significantly enriched in 91 GO terms and 16 KEGG pathways. Finally, the green module with |correlation| > 0.3 was found to be closely related to the subtypes and survival status; further, the top10 hub genes were obtained. …”
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28589
Spatiotemporal requirements of nuclear β-catenin define early sea urchin embryogenesis.
Published 2024-11-01“…Moreover, we found that 2 of the vegetal germ layers, the non-skeletogenic mesoderm and the endoderm, further require a prolonged period of nuclear β-catenin activity after their specification to maintain their respective germ layer identities through time. Finally, we determined that restriction of the anterior neuroectoderm territory depends on at least 2 nuclear β-catenin-dependent inputs and a nuclear β-catenin-independent mechanism. …”
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28590
Merck Open Global Health Library in vitro screening against Schistosoma mansoni identified two new substances with antischistosomal activities for further development
Published 2025-02-01“…Abstract Background Schistosomiasis, which is caused by the parasite Schistosoma mansoni as well as other species of the trematode genus Schistosoma, leads to chronic inflammation and finally to liver fibrosis. If untreated, the disease can cause life-threatening complications. …”
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28591
Early Biomarkers for Detecting Subclinical Exposure to Fumonisin B1, Deoxynivalenol, and Zearalenone in Broiler Chickens
Published 2024-12-01“…On d14, birds in T6 showed significant upregulation of liver miRNAs, gga-let-7a-5p (14.17-fold), gga-miR-9-5p (7.05-fold), gga-miR-217-5p (16.87-fold), gga-miR-133a-3p (7.41-fold), and gga-miR-215-5p (6.93-fold) (<i>p</i> < 0.05) and elevated serum fluorescein isothiocyanate-dextran (FITC-d) concentrations, aspartate aminotransferase (AST), and creatine kinase (CK) levels compared to the control (<i>p</i> < 0.05). …”
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28592
Biological significance of soluble IL-2 receptor
Published 1993-01-01“…On the other hand, it cannot exclude that sIL-2R is a by-product without biological significance. Finally, it is puzzling that in many conditions in which an increase of blood sIL-2R values has been observed, MNCs display a decreased in vitro capacity to produce sIL-2R. …”
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28593
Extracellular Vesicles in Periodontitis: Pathogenic Mechanisms and Therapeutic Potential
Published 2025-01-01“…Ling Zhang,1,* Xiaotong Li,2,* Bin Zhang,3 Ruiji Li4 1School of Nursing, Jining Medical University, Jining, Shandong, 272067, People’s Republic of China; 2Department of Stomatology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 3Department of Laboratory Medicine, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272001, People’s Republic of China; 4School of Pharmacy, Jining Medical University, Rizhao, Shandong, 276826, People’s Republic of China*These authors contributed equally to this workCorrespondence: Ruiji Li, School of Pharmacy, Jining Medical University, Xueyuan Road 669, Rizhao, Shandong, 276826, People’s Republic of China, Tel +86-15762380824, Email li-ruiji@mail.jnmc.edu.cnAbstract: Periodontitis is a prevalent yet frequently overlooked oral disease that is linked to a range of systemic conditions. …”
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28594
Examining the complementarity in belowground water use between different varieties and ages of Arabica coffee plants and dominant shade tree species in an organic agroecosystem
Published 2025-02-01“…Deeper soil water (60–120 cm; 45–69 %) was the main source for the shade trees, but important differences were observed among species, showing the potential of minimizing competition for water through tree species selection. Finally, our study shows that water uptake from groundwater sources increased with increasing tree size.…”
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28595
Sensitive windows for within- and trans-generational plasticity of anti-predator defences
Published 2023-08-01“…This suggests that transgenerational plasticity, although linked to within-generational plasticity by the embryonic sensitive window, may also be induced via a specific channel, independent of within-generational plasticity induction and expression. Finally, the late developmental window was never a sensitive window of transgenerational plasticity as it was theoretically expected. …”
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28596
CDC25B Is a Prognostic Biomarker Associated With Immune Infiltration and Drug Sensitivity in Hepatocellular Carcinoma
Published 2024-01-01“…Gene set enrichment analysis (GSEA) was used to identify signaling pathways enriched in CDC25B expression, and differential genes (DEGs) were used to screen out coexpressed hub genes and construct protein-protein interaction (PPI) networks. 5-Ethynyl-2′-deoxyuridine (EDU) staining was used to compare the proliferation and differentiation ability of the HCC cell line (HCC-LM3) after knockdown of CDC25B. Finally, we investigated the mutation of CDC25B in HCC and the relationship between CDC25B expression and tumor cell infiltration of lymphocytes and some immune checkpoints as well as drug sensitivity. …”
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28597
Palmitic Acid Methyl Ester Induces G2/M Arrest in Human Bone Marrow-Derived Mesenchymal Stem Cells via the p53/p21 Pathway
Published 2019-01-01“…The results from the present study show that PAME significantly reduced the levels of G2/M phase regulatory proteins, cyclin-dependent kinase 1 (Cdk1), and cyclin B1 and inhibited proliferation in hBM-MSCs. …”
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28598
Shared genetics between breast cancer and predisposing diseases identifies novel breast cancer treatment candidates
Published 2024-11-01“…In this manner, we are able to prioritize a list of drugs based on each predisposing disease, with each drug linked to a set of implicating pathways. Finally, we evaluate our recommendations against drugs currently under investigation for breast cancer. …”
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28599
Fast and Slow Roasting of Alcohol- and Honey-infused Coffee Blends: A Comparative Study of PAH and N-PAH Emissions
Published 2023-12-01“…The PAH diagnostic ratios indicated that the source of PAHs in green coffee was pyrogenic in nature and more specifically, petroleum combustion. Finally, the emission factors for the fast and slow roasting of green coffee were 1.36 mg kg−1 of coffee (7.49 µg BaP-TEQ kg−1) and 0.483 mg kg−1 (1.35 µg BaP-TEQ kg−1), respectively. …”
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28600
In the Plots of Neoliberalism: the Impact of AirBnb on Hotel Industry and the Real Estate Market in São Paulo and Rio de Janeiro, Brazil
Published 2024-12-01“…Furthermore, although no evidence was found that this platform has had a significant impact on hotel occupancy rates, ADR and RevPAR in these cities in recent years, the competition between AirBnb and hotel industry is considered unfair. Finally, there are signs of an impact on the real estate market typologies in both São Paulo and Rio de Janeiro, where there has been an increase in real estate launches explicitly aimed at seasonal rentals.…”
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