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28541
DEPDet: A Cross-Spatial Multiscale Lightweight Network for Ship Detection of SAR Images in Complex Scenes
Published 2024-01-01“…Moreover, to enhance the fusion of features at diverse scales, we design a new path aggregation feature pyramid network DEPAFPN, which combines deformable convolution and CSMSC2F. Finally, we introduce partial convolution to construct a lightweight detection head module PCHead, which can be employed to extract spatial features with greater efficiency. …”
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28542
Efficacy of high-dose steroids versus low-dose steroids in the treatment of immune checkpoint inhibitor-associated myocarditis: a case series and systematic review
Published 2025-02-01“…The primary aim was to compare clinical outcomes and therapeutic responses between patients treated with high-dose versus low-dose methylprednisolone.ResultsPatients receiving an initial high-dose intravenous methylprednisolone (1 g/day) exhibited a more rapid reduction in myocardial injury markers, including troponin I/T (cTnI/T), creatine kinase (CK), and N-terminal pro b-type natriuretic peptide (NT-proBNP), compared to those receiving lower doses. …”
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28543
Blockchain-Driven Optimized Chaotic Encryption Scheme for Medical Image Transmission in IoT-Edge Environment
Published 2025-01-01“…The experimental findings reveal that the suggested framework establishes a more robust and secure environment for image exchange, surpassing the performance of other blockchain-based systems in terms of integrity, robustness and security. Finally, the paper spreads the bright light of advantages in deploying the proposed framework to formulate the most secured environment in the IoT-Edge environment for medical image transmission.…”
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28544
Clinical manifestations, para-clinical features and outcome of Iranian adults with respiratory syncytial virus (RSV) infection: a report from hospitalized patients
Published 2025-02-01“…Notably, biochemical and inflammatory markers such as CRP, ESR, and LDH were significantly elevated beyond the normal range. Finally, five patients (13.9%) who received intensive care treatments died. …”
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28545
How does the ultrasonic assist CO2 immiscible flooding?
Published 2025-03-01“…Next, the changes in oil recovery and residual oil distribution after applying ultrasonic-assisted CO2 immiscible flooding were analyzed. Finally, the mechanism of EOR through ultrasonic-assisted CO2 immiscible flooding was summarized based on the results of interfacial tension (IFT) tests. …”
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28546
Activin A promoted the anti‐tumor effect of ActRIIA high CD8+ T cells in mouse hepatoma
Published 2025-01-01“…Additionally, these cells have a high proliferative potential. Finally, overexpression of Mettl3 inhibited the expression of ActRIIA in CD8+ T cells. …”
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28547
First-principles calculations to investigate thermoelectric, thermophysical, and optical properties of RNi₄P₁₂ (R = Sm, Eu) rare-earth metal skutterudites
Published 2024-12-01“…Elastic parameters are estimated using the Voigt-Reuss-Hill approximation, with elastic stability crucial for practical applications, characterized by brittleness indicating the compounds’ ability to deform without fracturing under stress. Finally, transport and thermal properties are analyzed, providing insights into conductivity and heat dissipation characteristics. …”
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28548
Successful Achievement of Demanding Outcomes in Upadacitinib-Treated Atopic Dermatitis Patients: A Real-World, 96-Week Single-Centre Study
Published 2025-01-01“…Abstract Introduction Results from randomized controlled trials of upadacitinib, a Janus kinase (JAK) inhibitor, have led to its approval for the treatment of moderate-to-severe atopic dermatitis (AD) in patients aged ≥ 12 years. …”
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28549
Inhibition of S100A8/A9 ameliorates neuroinflammation by blocking NET formation following traumatic brain injury
Published 2025-04-01“…Further experiments with PAD4 knockout mice confirmed that the reduction of NETs could substantially alleviate S100A8/A9-driven neuroinflammation. Finally, we established that the suppression of NET formation by S100A8/A9 inhibition is primarily mediated through the AMPK/Nrf2/HO-1 signaling pathway. …”
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28550
Contact-dependent growth inhibition (CDI) systems deploy a large family of polymorphic ionophoric toxins for inter-bacterial competition.
Published 2024-11-01“…Group 5 exploits homologous putrescine import proteins encoded by puuP and plaP, and group 6 toxins recognize di/tripeptide transporters encoded by paralogous dtpA and dtpB genes. Finally, we find that the ionophore domains exhibit significant intra-group sequence variation, particularly at positions that are predicted to interact with CdiI. …”
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28551
Identification of Breast Cancer Biomarkers by Constructing Protein-Protein Interaction and miRNAs-mRNAs Networks
Published 2025-01-01“…STRING v9. 1 and cytoHubba plugin in Cytoscape (v3.9.1) were used to investigate PPI network construction and identification of hub genes. Finally, key microRNAs (miRNAs) were predicted.Results: After protein-protein interaction analysis, a total of 10 upregulated DEMs (DLGAP5, CCNB1, TTK, NUSAP1, RRM2, BUB1B, CDK1, CENPF, TOP2A, and ASPM) and 10 downregulated DEMs (PPARG, LIPE, CD36, FABP4, SCD, LPL, DGAT2, PNPLA2, ACSL1, and LEP) were screened as hub genes. …”
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28552
Measuring effective indicators for waste disposal in order to assess the sustainable environment: application of fuzzy approach
Published 2023-09-01“…Multiple alternatives and evaluation attributes need to be analyzed to finalize the locations of these facilities. The selection of a landfill site in an urban area is a critical issue due to the involvement of many parameters. …”
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28553
Physical and emotional abuse with internet addiction and anxiety as a mediator and physical activity as a moderator
Published 2025-01-01“…Subsequently, the relationships among the variables were explored using pearson correlation analysis. Finally, mediation and moderation models were assessed using the SPSS PROCESS macro plugin. …”
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28554
<i>In silico</i> mapping of coronary artery disease genes
Published 2020-01-01“…They can be considered as new candidate genes. Finally, we identified sixteen new genes (AGPAT4, ARHGEF12, BDP1, DHX58, EHBP1, FBF1, HSPB9, NPBWR2, PDLIM5, PLCB3, PLEKHM2, POU2F3, PRKD2, TMEM136, TTC29 and UTP20) outside the known loci. …”
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28555
Biodistribution of a Mitochondrial Metabolic Tracer, [18F]F-AraG, in Healthy Volunteers
Published 2022-01-01“…The biodistribution was generally reflective of the expression and activity profiles of the enzymes involved in [18F]F-AraG’s cellular accumulation, mitochondrial kinase dGK, and SAMHD1. The highest uptake was observed in the kidneys and liver, while the brain, lung, bone marrow, and muscle showed low tracer uptake. …”
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28556
Intravesical BCG in patients with non-muscle invasive bladder cancer induces trained immunity and decreases respiratory infections
Published 2023-01-01“…An epigenomics approach combining chromatin immuno precipitation-sequencing and RNA-sequencing with in vitro trained immunity experiments identified enhanced inflammasome activity in BCG-treated individuals. Finally, germline variation in genes that affect trained immunity was associated with recurrence and progression after BCG therapy in NMIBC.Conclusion We conclude that BCG immunotherapy induces trained immunity in NMIBC patients and this may account for the protective effects against respiratory infections. …”
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28557
Memorias trans: género, orientalismo, anarquismo e islam en Isabelle Eberhardt y Leda Rafanelli
Published 2025-01-01“…El objetivo de este trabajo es problematizar el anarquismo transnacional de finales del siglo XIX y principios del siglo XX –estudiado principalmente desde un prima masculino y occidental– con el fin de priorizar una mirada de género y poscolonial. …”
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28558
Decidualized ovarian and rectouterine deep endometriosis disguised as malignancy in the second-trimester of pregnancy: A case report
Published 2025-01-01“…This patient recovered well and then went to the department of obstetrics for high-risk pregnancy supervision. Finally, the baby was delivered at 39 weeks by cesarean section because of fetal growth restriction (FGR). …”
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28559
Imprint of ancestral and modern threats in human mind – experience of fear, disgust, and anger
Published 2025-01-01“…However, as disgust declines with age, the brain must adaptatively shift the emotional processing from disgust to fear to protect older adults from contamination risks. Finally, our study reveals that pandemic fear is better predicted by specific behaviors rather than general anxiety, suggesting a need for new assessments.…”
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28560
Elucidating the effects of manganese on the growth and cadmium accumulation of OsNRAMP5 mutant rice
Published 2025-02-01“…Furthermore, both hydroponic and pot experiments show that Cd concentrations in ZA7 were significantly lower than those in ZZ35, and decreased further with increasing Mn supply. Finally, the relationship between soil available-Mn (diethylene-triamine-pentaacetic acid-extractable, DTPA-Mn), which is directly related to plant Mn uptake, and ZA7 grain yields fitted well. …”
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