A Synchronized Hybrid Brain-Computer Interface System for Simultaneous Detection and Classification of Fusion EEG Signals by Dalin Yang, Trung-Hau Nguyen, Wan-Young Chung

“…Furthermore, a four-layer convolutional neural network (CNN) is used as a classifier to distinguish different mental tasks. Finally, the hybrid MI + SSVEP system with a simple structure achieves a high accuracy of 95.56%. …”
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CT-based scoring system for diagnosing eosinophilic solid and cystic renal cell carcinoma versus clear cell renal cell carcinoma by Sunya Fu, Dawei Chen, Yuqin Zhang, Yuguo Wei, Yuning Pan

“…The two groups were matched on a 1:2 basis using the propensity-score-matching (PSM) method, with matching factors including sex and age. Finally, 25 ESC-RCC and 50 ccRCC cases were included and randomly divided into a training cohort (52 cases) and a validation cohort (23 cases). …”
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Investigating the Relationship between SHRM and Organizational Performance by Mediating Role of Management Capability and Entrepreneurial Orientation (Case Study: Veterinary Medici... by Mehdi Ajalli, Ehsan Hemmati

“…Also, managerial ability explains 58% of organizational performance changes, and entrepreneurial orientation explains 48% of organizational performance changes. Finally, organizational performance is 63% due to changes in financial performance and 52% due to changes in employee performance. …”
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FNDC5/irisin mitigates the cardiotoxic impacts of cancer chemotherapeutics by modulating ROS-dependent and -independent mechanisms by Manish Kumar, Abhishek Singh Sengar, Anushree Lye, Pranesh Kumar, Sukhes Mukherjee, Dinesh Kumar, Priyadip Das, Suvro Chatterjee, Adele Stewart, Biswanath Maity

“…Intriguingly, we identified two parallel signaling cascades impacted by FNDC5 in cardiomyocytes: the ROS-driven intrinsic mitochondrial apoptosis pathway and the ROS-independent Ataxia Telangiectasia and Rad3-Related Protein (ATR)/Checkpoint Kinase 1 (Chk1) pathway. In fact, FNDC5 forms a co-precipitable complex with Chk1 alluding to possible intracellular actions for this canonically membrane-associated protein. …”
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Patient-Reported Outcomes in Children Undergoing the Modified Green Procedure for Treating Sprengel’s Deformity: Results from a Multicentric Study by Giovanni Trisolino, Paola Zarantonello, Marco Todisco, Giovanni Luigi Di Gennaro, Grazia Chiara Menozzi, Philipp Scheider, Alessandro Depaoli, Diego Antonioli, Gino Rocca, Sebastian Farr

“…Several dedicated questionnaires such as QuickDASH, the Shoulder Pain Index and the Shoulder Disability Index (SPADI) and finally the UCLA Shoulder Scale were submitted to assess the quality of life of the subjects and the ability to practice certain activities, including work and sports. …”
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Extracellular vesicles, RNA sequencing, and bioinformatic analyses: Challenges, solutions, and recommendations by Rebecca T. Miceli, Tzu‐Yi Chen, Yohei Nose, Swapnil Tichkule, Briana Brown, John F. Fullard, Marilyn D. Saulsbury, Simon O. Heyliger, Sacha Gnjatic, Natasha Kyprianou, Carlos Cordon‐Cardo, Susmita Sahoo, Emanuela Taioli, Panos Roussos, Gustavo Stolovitzky, Edgar Gonzalez‐Kozlova, Navneet Dogra

“…Here, we address these gaps by describing the following points by (1) focusing on the large canopy of the EVs and particles (EVPs), which includes, but not limited to – exosomes and other large and small EVs, lipoproteins, exomeres/supermeres, mitochondrial‐derived vesicles, RNA binding proteins, and cell‐free DNA/RNA/proteins; (2) examining the potential functional roles and biogenesis of EVPs; (3) discussing various transcriptomic methods and technologies used in uncovering the cargoes of EVPs; (4) presenting a comprehensive list of RNA subtypes reported in EVPs; (5) describing different EV‐RNA databases and resources specific to EV‐RNA species; (6) reviewing established bioinformatics pipelines and novel strategies for reproducible EV transcriptomics analyses; (7) emphasizing the significant need for a gold standard approach in identifying EV‐RNAs across studies; (8) and finally, we highlight current challenges, discuss possible solutions, and present recommendations for robust and reproducible analyses of EVP‐associated small RNAs. …”
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Tele-rehabilitation for children with physical disabilities: qualitative exploration of challenges in Iran by Mahta Alsadat Aarabi, Kianoush Abdi, Farin Soleimani

“…The 10 categories are as follows: unorganized internet infrastructure, lack of a developed program, inefficient technology, disregard for ethical principles, lack of therapist information, visual and auditory limitations, cultural misconceptions, weakness of empathy and therapeutic alliance, Lack of familiarity with telerehabilitation, and the other online therapy problems. Conclusion Finally, by identifying these challenges, it is possible to provide services with higher qualities to people of this group by reducing barriers. …”
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Numerical Simulation of CAARC Standard High-Rise Building Model Based on MRT-LBM Large Eddy Simulation by Rui Zhao, Zehua Feng, Danhui Dan, Yuhang Wu, Xianduo Li

“…Three LBM large eddy simulation models, MRT-LBM-WALE, MRT-LBM-DSM, and MRT-LBM-SM, which can simulate the flow around a bluff body with high Rayleigh number, are constructed by using the subgrid eddy viscosity to modify the kinematic viscosity of LBM. Finally, the three turbulence models are used to simulate and analyze the three-dimensional steady wind flow field of a single high-rise building of the standard CAARC high-rise building model in the atmospheric boundary layer, and the numerical results are analyzed and compared with the wind tunnel test results. …”
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Integration of machine learning and experimental validation to identify the prognostic signature related to diverse programmed cell deaths in breast cancer by Longpeng Li, Longpeng Li, Jinfeng Zhao, Yaxin Wang, Zhibin Zhang, Wanquan Chen, Jirui Wang, Yue Cai

“…Potential drugs targeting key genes were analyzed by Cmap. Finally, the expression levels of key genes in clinical tissues were verified by RT-PCR.ResultsPCDS showed higher levels in cancer compared to normal. …”
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In vitro gastrointestinal digestion simulation screening of novel ACEI peptides from broccoli: mechanism in high glucose-induced VSMCs dysfunction by Shuzhi Zhang, Jingjing Guo, Shikun Suo, Li Ju, Zhaoqiang Jiang, Pingshuan Dong, Yanli Wang, Yali Dang, Laijing Du

“…This indicates that HG elevated Ang II levels. Finally, five peptides significantly attenuated Ang II-induced VSMCs proliferation and migration by down-regulating AT1R expression and inhibiting ERK and p38 MAPK phosphorylation. …”
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Characterizing the Flow and Interaction of Microbubbles in a 2D Capillary Network for Targeted Drug Delivery: A Simulation Study by Sadegh Shurche, Akram Shahidani, Roghaye Bodaghi Hossein Abadi

“…Meanwhile, the maximum velocity was 5.59 mm/s, and the minimum and maximum pressure values were 303.13 Pa and 0.42 Pa. Finally, the MB-MB interaction force exceeded the Brownian and gravitational forces. …”
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Comparative analysis of anticoagulant influence on PMI estimation based on porcine blood metabolomics profile measured using GC-MS by Patrycja Mojsak, Paulina Samczuk, Paulina Samczuk, Paulina Klimaszewska, Michal Burdukiewicz, Michal Burdukiewicz, Jaroslaw Chilimoniuk, Krystyna Grzesiak, Krystyna Grzesiak, Karolina Pietrowska, Justyna Ciborowska, Anna Niemcunowicz-Janica, Adam Kretowski, Adam Kretowski, Michal Ciborowski, Michal Ciborowski, Michal Szeremeta

“…Thus, we identified 41 metabolites with time−dependent intensities that were not susceptible to EDTA presence. Finally, we assessed the performance of these metabolites in a PMI predictive model. …”
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First Measurements of Ambient PM2.5 in Kinshasa, Democratic Republic of Congo and Brazzaville, Republic of Congo Using Field-calibrated Low-cost Sensors by Celeste McFarlane, Paulson Kasereka Isevulambire, Raymond Sinsi Lumbuenamo, Arnold Murphy Elouma Ndinga, Ranil Dhammapala, Xiaomeng Jin, V. Faye McNeill, Carl Malings, R. Subramanian, Daniel M. Westervelt

“…We estimated an average annual PM2.5 concentration of 43.5 µg m−3 in Kinshasa for 2019, which exceeds the World Health Organization (WHO)’s Interim Target 1 (10 µg m−3) by 4 times. Finally, the surface PM2.5 level and the aerosol optical depth were about 40% lower during the COVID-19 lockdown in 2020 than the corresponding period in 2019, which cannot be attributed solely to changes in meteorology or wildfire emission. …”
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A Novel Risk Score Model for the Differential Diagnosis of Type 2 Diabetic Nephropathy: A Multicenter Study by Yuetong Zhao, Lin Liu, Li Zuo, Xianghai Zhou, Song Wang, Hongwei Gao, Feng Yu, Xiaomei Zhang, Mi Wang, Ling Chen, Rui Zhang, Fang Zhang, Shuhong Bi, Qiong Bai, Jiaxiang Ding, Qinghua Yang, Sixu Xin, Sanbao Chai, Min Chen, Junqing Zhang

“…We used univariate and multivariate logistic regression analyses to identify independent risk factors of DN in the training group and conducted multivariate logistic regression analysis with these independent risk factors in the training group to find regression coefficients “β” to establish a risk score model. Finally, we conducted internal and external validation of the model with ROC curves. …”
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Papaverine Enhances the Oncolytic Effects of Newcastle Disease Virus on Breast Cancer In Vitro and In Vivo by Sura Akram, Ahmed Majeed Al-Shammari, Hayder B. Sahib, Majid Sakhi Jabir

“…Evaluation of the antitumor activity included growth inhibition measurement; the immunohistochemistry assay measured caspase protein expression. Finally, a semiquantitative microarray assay was used to screen changes in apoptotic proteins. …”
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Evaluación bibliométrica de la investigación sobre Tecnologías Habilitadoras para la Transformación Digital en Cuba by Yudayly Stable-Rodríguez, Lee Yang Díaz-Chieng, Alfredo Javier Pérez Gamboa, Esteban Rodríguez-Torres

“…Además, permitió comparar las tendencias mostradas por la producción científica cubana con respecto al contexto internacional. Se ofrecen ideas finales sobre futuras líneas de investigación y la importancia de los resultados encontrados.…”
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A Comparative Study of VMD-Based Hybrid Forecasting Model for Nonstationary Daily Streamflow Time Series by Hui Hu, Jianfeng Zhang, Tao Li

“…The ensemble forecast was finally reconstructed by summing. Historical daily streamflow series recorded at the Wushan and Weijiabao hydrologic stations from 1 January 2001 to 31 December 2014 in China were investigated using the proposed VMD-based models. …”
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Enhancing unity-based AR with optimal lossless compression for digital twin assets. by Mohammed Hlayel, Hairulnizam Mahdin, Mohammad Hayajneh, Saleh H AlDaajeh, Siti Salwani Yaacob, Mazidah Mat Rejab

“…Experimental results show a detailed comparison among these compression algorithms, which can give insights and help choose the best method according to the compression ratio, decompression speed, and resource usage. It finally leads to more efficient implementations of AR digital twins on resource-constrained mobile platforms with greater flexibility in development and a better end-user experience. …”
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SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease by Mridula Bhalla, Jinhyeong Joo, Daeun Kim, Jeong Im Shin, Yongmin Mason Park, Yeon Ha Ju, Uiyeol Park, Seonguk Yoo, Seung Jae Hyeon, Hyunbeom Lee, Junghee Lee, Hoon Ryu, C. Justin Lee

“…We checked for the presence of SIRT2 in human AD patients as well as the mouse model APP/PS1 and finally, we selectively ablated SIRT2 in the astrocytes of APP/PS1 mice to observe its effects on pathology. …”
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NT-proBNP and Major Adverse Cardiovascular Events in Patients with ST-Segment Elevation Myocardial Infarction Who Received Primary Percutaneous Coronary Intervention: A Prospective... by Zuoan Qin, Yaoyao Du, Quan Zhou, Xuelin Lu, Li Luo, Zhixiang Zhang, Ning Guo, Liangqing Ge

“…Age, number of implanted stents, Killip class, infarction-related artery, applied intra-aortic balloon pump (IABP), creatine kinase (CK) peak value, CK-MB peak value, TnI peak value, and ST-segment resolution were independently associated with MACE (P<0.05). …”
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