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27781
Supportive functions of soil organic carbon for ecosystem services in karst desertification areas
Published 2025-01-01“…The trade-off/synergy relationship between all the factors was discussed, and the shortcomings of the different ecosystems were identified. Finally, an optimization model with high synergy between each ecosystem service was proposed. …”
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27782
Silencing of STEAP3 suppresses cervical cancer cell proliferation and migration via JAK/STAT3 signaling pathway
Published 2024-12-01“…Western blotting was performed to detect the expression of related proteins, including epithelial-mesenchymal transition (EMT) and Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling markers. …”
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27783
Strategic Analysis of the Financing System of Iran Health Insurance Organization
Published 2024-12-01“…The main threats to IHIO include political and economic unstability, low health insurance premiums, decisions without scientific support and insufficient enforcement of laws. Finally, solutions such as modernizing the tax system, increasing the health literacy of the community, reducing bureaucracy, increasing transparency and accountability, and reforming the monitoring and evaluation system were identified to strengthen the performance of the financing system of IHIO. …”
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27784
Current methods for detecting and assessing HIV-1 antibody resistance
Published 2025-01-01“…Furthermore, in vivo studies in animal models have revealed the rapid emergence of escape variants to mono- or combined bNAb treatments. Finally, similar variants were found in the first clinical trials testing bNAbs for the treatment of HIV-1-infected patients. …”
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27785
Mannan-Binding Lectin Suppresses Peptidoglycan-Induced TLR2 Activation and Inflammatory Responses
Published 2019-01-01“…Administration of MBL alone did not have an effect on the expression of TLR2. Finally, our data showed that PGN-mediated immune responses were more severely suppressed by preincubation with MBL and indicated that MBL can combine with both TLR2 and PGN to block the inflammation cytokine expression induced by PGN. …”
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27786
Quality control and safety management of oil and gas pipelines during its whole life cycle
Published 2023-10-01“…Then, a new construction quality and operation safety model with "quality control as the basis, total-factor management as the core and enhanced whole life cycle risk resistance" was put forward. Finally, the technical direction of quality control and safety management of oil and gas pipelines was prospected based on the application of "Industrial Internet +" and digital technology.…”
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27787
Effects of Meaningful Action Observation Therapy on Occupational Performance, Upper Limb Function, and Corticospinal Excitability Poststroke: A Double-Blind Randomized Control Tria...
Published 2022-01-01“…Both assessors of clinical and neurophysiological outcomes were blinded to the allocation of subjects. Result. Finally, the results of outcomes in 24 patients who completed the study were analyzed. …”
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27788
Changing of expression actinbinding proteins in the kidney under dehydration
Published 2018-04-01“…The most probable molecular mechanism of changing the expression of the genes for alpha-actinin and tropomyosin is transduction of the V2-mediated vasopressin hormonal signal to protein kinase A, phosphorylation of the cAMPresponsible transcriptional factor CREB, and nuclear CREB interaction with gene CRE sites sensitive to it.…”
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27789
Experimental study on the bearing capacity and effective anchorage lengths of inclined steel grouting pipes in loess embankment slope.
Published 2024-01-01“…Thirdly, effective anchorage lengths of inclined steel grouting pipe with anchorage lengths of 6 m, 9 m, and 12 m were compared and analyzed. Finally, inclined steel grouting pipe average cohesive strength along effective anchorage length section at the interface between cement grouting and soil stratum was compared with that of rock bolt. …”
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27790
Tuberculosis and COVID-19: Lessons from the Past Viral Outbreaks and Possible Future Outcomes
Published 2020-01-01“…Second, although challenging due to data scarcity, investigating the pathological pathways linking TB and SARS-CoV-2 leads to the idea that their coexistence might yield a more severe clinical evolution. Finally, we addressed the issues of vaccination and diagnostic reliability in the context of coinfection. …”
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27791
Adaptation and combination of two scales to measure dispositional gratitude in health sciences faculty: a psychometric analysis
Published 2025-02-01“…The validation of the one-factor model with convergent reliability and validity suggests that the total scale score serves as an adequate measure of gratitude. Finally, it represents a valuable contribution to the teaching of health sciences since it generates healthy environments with prosocial attitudes that facilitate flourishing in personal and academic life, and in the future, health professionals with humanism as their standard.…”
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27792
Serum Glial Cell Line-Derived Neurotrophic Factor (sGDNF) Is a Novel Biomarker in Predicting Cirrhosis in Patients with Chronic Hepatitis B
Published 2022-01-01“…On multivariable regression, sGDNF was independently associated with cirrhosis with an odds ratio of 6.98 (95% CI: 1.10–17.94). Finally, we demonstrated that sGDNF outperformed AST to platelet ratio index, FIB-4, fibroscore, forn index, and fibrometer in differentiating F4 vs. …”
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27793
The role of SASP in ischemic stroke: a deep dive into cellular mechanisms
Published 2025-01-01“…Investigated immune infiltration in stroke patients, managed quality control and annotation of single-cell data, cherry-picked central cells based on SASP scores, unearthed essential genes via enrichment analysis, conducted pseudo-time and intercellular communication studies, and prognosticated drugs for hub genes. Finally, authenticated core gene expression in serum of MCAO and Sham rats using real-time fluorescent polymerase chain reaction (RT-qPCR).ResultsFourteen hub genes were discerned. …”
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27794
Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies
Published 2015-12-01“…Data from eligible studies were extracted, and the meta-analysis was performed by using the STATA software V.12.0.Results 14 studies were finally included in the analysis. The results showed that overweight and obesity were significantly associated with higher knee OA risks of 2.45 (95% CI 1.88 to 3.20, p<0.001) and 4.55 (95% CI 2.90 to 7.13, p<0.001), respectively. …”
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27795
Spatiotemporal Dynamics of Drought in the Huai River Basin (2012–2018): Analyzing Patterns Through Hydrological Simulation and Geospatial Methods
Published 2025-01-01“…On the other hand, we identified a time–lag relationship among meteorological, agricultural, and hydrological droughts, uncovering interactions and propagation mechanisms across different drought types in this basin. Finally, we concluded that the WRF-Hydro model can provide highly accurate soil moisture simulation results and can be used to assess the spatiotemporal variations in regional drought events and the propagation mechanisms between different types of droughts.…”
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27796
Spatio-temporal evolution characteristics and influencing factors of environmental welfare performance in Chinese cities
Published 2025-02-01“…Using the Hybrid-Network-DEA model, we measure the EWP of 240 cities in China, and then investigate the spatial distribution characteristics and spatio-temporal evolution patterns of EWP. Finally, empirical testing of the factors influencing EWP is conducted using spatial econometric methods.ResultsThe overall level of EWP in 240 Chinese cities from 2004 to 2019 is relatively low, but it generally shows a wavy upward trend. …”
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27797
Mémoires sous vitrines : mises en scènes de l’esclavage dans les musées du Bénin et du Ghana
Published 2009-11-01“…Trois éléments structurels permettent d’opérer ce double langage à travers lequel l’histoire mise en scène vient finalement valider l’idéologie inhérente à chacune de ces trois nations. …”
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27798
Optical band gap modulation in functionalized chitosan biopolymer hybrids using absorption and derivative spectrum fitting methods: A spectroscopic analysis
Published 2025-01-01“…The dopped samples show an increase in their linear optical susceptibility, third-order nonlinear optical susceptibility and nonlinear refractive indices, changing from 3.165 × 10–15 to 2.831 × 10–12 esu. Finally, light propagation velocities, surface resistance, and thermal emissivity were also examined.…”
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27799
Molecular Alterations of KIT Oncogene in Gliomas
Published 2007-01-01“…KIT, a class III receptor tyrosine kinase (RTK), is frequently involved in tumourigenic processes. …”
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27800
A novel social-network-analysis-based approach for analyzing complex network of actors involved in accessibility of anti-cancer medications in Iran
Published 2024-12-01“…Then, the influence relationships of these actors were comprehensively analysed through in-depth interviews with nine key informants involved in pharmaceutical policies through a structured questionnaire. Finally, a novel network of actors was determined accordingly, and a SNA-based approach proposed to reveal the intrinsic roles and various aspects of the importance of the network’s actors. …”
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