Drug Abuse Prevention Among Students In Improving The Lives Meaning Through Counseling Logo by Kadek Suranata

“…Abuse of drugs, psychotropic substances, illegal drugs and other addictive substances (drugs) among teenagers especially students to be a problem from time to time keeps going on and it seems difficult to be finalized. So also in Indonesia drug abuse prevention efforts at the level of the student and the student assessment has been a great school for education practitioners and also involving relevant agencies such as BNN, BKKBN, the health department and the police. …”
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Exploring Heat-Response Mechanisms of MicroRNAs Based on Microarray Data of Rice Post-meiosis Panicle by Yan Peng, Xianwen Zhang, Yuewu Liu, Xinbo Chen

“…Then, GO-Slim classification and functional identification of these 178 target genes showed that (1) miRNAs were mainly involved in a series of basic biological processes even under heat conditions; (2) some miRNAs might play important roles in the heat resistance (such as osa-miR164, osa-miR166, osa-miR169, osa-miR319, osa-miR390, osa-miR395, and osa-miR399); (3) osa-miR172 might play important roles in protecting the rice panicle under the heat stress, but osa-miR437, osa-miR418, osa-miR164, miR156, and miR529 might negatively affect rice fertility and panicle flower; and (4) osa-miR414 might inhibit the flowering gene expression by downregulation of LOC_Os 05g51830 to delay the heading of rice. Finally, a heat-induced miRNA-PPI (protein-protein interaction) network was constructed, and three miRNA coregulatory modules were discovered.…”
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Investigation on the Impacts of COVID-19 Lockdown and Influencing Factors on Air Quality in Greater Bangkok, Thailand by Parichat Wetchayont

“…Even low traffic emissions, on their own, did not cause an absolute reduction in air pollution since there are several primary emission sources that dominate the air quality over Greater Bangkok. Finally, these findings highlight the impact of COVID-19 lockdown measures not only on air pollution levels but on their effects on air pollution characteristics, as well.…”
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Psychiatric comorbidities in epilepsy: population co-occurrence, genetic correlations and causal effects by Neil M Davies, Dheeraj Rai, Harriet Forbes, Christina Dalman, Torbjörn Tomson, Daniel Berglind, Michael Lundberg, Cecilia Magnusson, Craig Newschaffer, Brian K Lee, Viktor H Ahlqvist, Paul Madley-Dowd, Christina Dardani, Jessica Rast, Caichen Zhong, Renee M Gardner, Kristen Lyall

“…We then used summary data from genome-wide association studies to investigate whether the identified observational associations could be attributed to a shared underlying genetic aetiology using cross-trait linkage disequilibrium score regression. Finally, we assessed the potential bidirectional relationships using two-sample Mendelian randomisation.Results In a cohort of 7 628 495 individuals, we found that almost half of the 94 435 individuals diagnosed with epilepsy were also diagnosed with a psychiatric condition in their lifetime (adjusted lifetime prevalence, 44.09%; 95% confidence interval (CI) 43.78% to 44.39%). …”
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The Role of the Commercial Space Industry within the US National Security under the Trump Administration by E. A. Kuznetsov

“…The fourth section thoroughly examines key forms and areas of the public–private partnership in commercial use of space, including launch services, communication services, intelligence gathering, as well as production and maintenance of satellites. Finally, the fifth section assesses the prospects for private space activities given the current tightness of the space services market and growing competition. …”
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Role of Astrocytic Dysfunction in the Pathogenesis of Parkinson’s Disease Animal Models from a Molecular Signaling Perspective by Lucas Udovin, Cecilia Quarracino, María I. Herrera, Francisco Capani, Matilde Otero-Losada, Santiago Perez-Lloret

“…Another major pathway involves IκB kinase (IKK) downregulation by ARL6ip5 (ADP-ribosylation-like factor 6 interacting protein 5, encoded by the cell differentiation-associated, JWA, gene). …”
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Global outcomes and prognosis for relapsed/refractory mature T-cell and NK-cell lymphomas: results from the PETAL consortium by Jessy Xinyi Han, Min Jung Koh, Leora Boussi, Mark Sorial, Sean M. McCabe, Luke Peng, Shambhavi Singh, Ijeoma Julie Eche-Ugwu, Judith Gabler, Maria J. Fernandez Turizo, Caroline T. MacVicar, Aditya Garg, Alexander Disciullo, Kusha Chopra, Alexandra Lenart, Emmanuel Nwodo, Jeffrey Barnes, Min Ji Koh, Eliana Miranda, Carlos Chiattone, Robert Stuver, Steven M. Horwitz, Mwanasha Merrill, Eric Jacobsen, Martina Manni, Monica Civallero, Tetiana Skrypets, Athina Lymboussaki, Massimo Federico, Yuri Kim, Jin Seok Kim, Jae Yong Cho, Thomas Eipe, Tanuja Shet, Epari Sridhar, Alok Shetty, Saswata Saha, Hasmukh Jain, Manju Sengar, Carrie Van Der Weyden, Henry Miles Prince, Ramzi Hamouche, Tinatin Murdashvili, Francine Foss, Marianna Gentilini, Beatrice Casadei, Pier Luigi Zinzani, Takeshi Okatani, Noriaki Yoshida, Sang Eun Yoon, Won-Seog Kim, Girisha Panchoo, Zainab Mohamed, Estelle Verburgh, Jackielyn Cuenca Alturas, Mubarak Al-Mansour, Josie Ford, Maria Elena Cabrera, Amy Ku, Govind Bhagat, Helen Ma, Ahmed Sawas, Khyati Maulik Kariya, Makoto Iwasaki, Forum Bhanushali, Owen A. O’Connor, Enrica Marchi, Changyu Shen, Devavrat Shah, Salvia Jain

“…In peripheral T-cell lymphoma–not otherwise specified and anaplastic lymphoma kinase–negative anaplastic large cell lymphoma (ALK– ALCL), patients with relapsed lymphoma demonstrated a superior median overall survival (OS) relative to refractory from the time of second-line treatment. …”
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Information retrieval interfaces in virtual reality-A scoping review focused on current generation technology. by Maurice Schleußinger

“…Although conventional retrieval features are less common, systems enable retrieval of literature, 3D objects, images, books and texts and arrange them in a virtual space (e.g. as grids, arcs or maps). Finally, many of these systems were compared to conventional counterparts through user evaluation (n = 10). …”
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Music listening evokes story-like visual imagery with both idiosyncratic and shared content. by Sarah Hashim, Lauren Stewart, Mats B Küssner, Diana Omigie

“…For each excerpt, listeners rated how much visual imagery they were experiencing and how vivid it was, their liking of and felt emotional intensity in response to the excerpt, and, finally, described the content of any visual imagery they may have been experiencing. …”
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Astragalin: A Bioactive Phytochemical with Potential Therapeutic Activities by Ammara Riaz, Azhar Rasul, Ghulam Hussain, Muhammad Kashif Zahoor, Farhat Jabeen, Zinayyera Subhani, Tahira Younis, Muhammad Ali, Iqra Sarfraz, Zeliha Selamoglu

“…It carries out the aforementioned activities by the regulation and modulation of various molecular targets such as transcription factors (NF-κB, TNF-α, and TGF-β1), enzymes (iNOS, COX-2, PGE2, MMP-1, MMP-3, MIP-1α, COX-2, PGE-2, HK2, AChe, SOD, DRP-1, DDH, PLCγ1, and GPX), kinases (JNK, MAPK, Akt, ERK, SAPK, IκBα, PI3K, and PKCβ2), cell adhesion proteins (E-cadherin, vimentin PAR-2, and NCam), apoptotic and antiapoptotic proteins (Beclin-1, Bcl-2, Bax, Bcl-xL, cytochrome c, LC3A/B, caspase-3, caspase-9, procaspase-3, procaspase-8, and IgE), and inflammatory cytokines (SOCS-3, SOCS-5, IL-1β, IL-4, IL-6, IL-8, IL-13, MCP-1, CXCL-1, CXCL-2, and IFN-γ). …”
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Design, Implementation and Environmental Impact of Cutoff Wall for Pollution Control in an Industrial Legacy Site by Lu Yu, Sichen Chen, Jinnan Wang, Zhihong Zhang, Yan Huang

“…A protocol for a cutoff wall (50 m length × 2 m width × 3 m height) was finally verified and applied at the real contaminated site for the blocking of compound pollutant diffusion. …”
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A novel FPGA‐Based Bi input‐reduced order extended Kalman filter for speed‐sensorless direct torque control of induction motor with constant switching frequency controller by Remzi Inan

“…Thus, the control and the implementation performances of digitalised emulator are tested. Finally, the estimation and control performance results and the execution time of the each part of the proposed HIL emulator of the speed‐sensorless BI‐ROEKF‐based CSFC‐DTC of the IM are presented.…”
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MicroRNA-101-3p Suppresses mTOR and Causes Mitochondrial Fragmentation and Cell Degeneration in COPD by Lei Fang, Xinggang Wang, Ming Zhang, Petra Khan, Michael Tamm, Michael Roth

“…The regulatory effect of miR-101-3p modification on mTOR expression, mitochondrial fragmentation, and remodeling properties (α-SMA, fibronectin, MTCO2, and p70S6 kinase) was assessed in ASMC (healthy nonsmokers: n = 3; COPD: n = 3) by Western blotting and immunofluorescence microscopy. …”
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Cardiac Injury Biomarkers and the Risk of Death in Patients with COVID-19: A Systematic Review and Meta-Analysis by Sami H. Alzahrani, Mohammed W. Al-Rabia

“…Secondary markers included creatine kinase-myocardial bound (CK-MB), myoglobin, interleukin-6 (IL-6), and C-reactive protein (CRP). …”
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Good practices for dialysis education, treatment, and eHealth: A scoping review. by Anita van Eck van der Sluijs, Sanne Vonk, Brigit C van Jaarsveld, Anna A Bonenkamp, Alferso C Abrahams

“…The good practices for dialysis treatment focus mainly on dialysis access devices and general quality improvement of dialysis care. Finally, eHealth is useful for HD and PD and affects both quality of care and health-related quality of life.…”
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Diagnóstico del cáncer mediante biomarcadores circulantes by Álvaro Pablo Moina-Veloz, Johan Alexander Maldonado-Carrasco, Diana Carolina Chiluiza-Tubon, Virginia Monserrath Ortiz-Vásquez

“…Los biomarcadores predictivos además proporcionan información sobre el efecto de una intervención terapéutica en el resultado y por tanto ofrece información valiosa para guiar la toma de decisiones en el tratamiento. Consideraciones finales: El estudio de biomarcadores en el diagnóstico del cáncer ha demostrado ser una herramienta prometedora con potencial aplicación clínica. …”
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2D-Action Asynchronous Cooperative Lane Change Trajectory Planning Method for Connected and Automated Vehicles by Liyang Wei, Weihua Zhang, Haijian Bai, Jingyu Li

“…A cooperative lane change trajectory evaluation objective function is constructed, considering multivehicle comfort and efficiency. Finally, the AALC model is solved in the continuous collision space according to the optimal objective function, and the lane change is divided into free, cooperative, and refused according to the optimization. …”
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An integrated investigation of mitochondrial genes in COPD reveals the causal effect of NDUFS2 by regulating pulmonary macrophages by Xiaoli Zou, Qiqing Huang, Tutu Kang, Shaoran Shen, Chenxi Cao, Jianqing Wu

“…Random forest (RF) analysis, least absolute shrinkage and selection operator (LASSO) regression, and Mendelian Randomization (MR) analysis of hub MitoDEGs further nominated NDUFS2, CAT, and MRPL2 as causal MitoDEGs for COPD, whose predominate expressions in pulmonary macrophages were revealed by an independent single-cell transcriptomic dataset of COPD human lungs. Finally, NDUFS2 was evaluated as the top-ranked contributor to COPD in the nomogram model and its downregulation in pulmonary macrophages could result in pro-inflammatory secretion, enhanced intercellular communications, whereas depressed phagocytosis of macrophages as revealed by gene set variation analysis (GSVA) and cell-cell interaction (CCI) analysis of single-cell transcriptomic dataset of COPD human lungs, which was later confirmed in COPD mouse model and macrophage cell lines. …”
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A Novel Case Base Reasoning and Frequent Pattern Based Decision Support System for Mitigating Software Risk Factors by Muhammad Asif, Jamil Ahmed

“…Thirdly, Case Based Reasoning (CBR) approach has been used to determine the previous cases as rules. Finally, automated rules have been generated to develop an intelligent DSS to mitigate the software risks. …”
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Pengaruh sedentary lifestyle terhadap kesehatan mental pada remaja by Tiara Ash Syafa, Misrah Misrah

“…Meanwhile, of the total of 18 respondents with a moderate sedentary lifestyle, 2 people (11.1%) experienced high mental health disorders, 16 people (88.9%) experienced moderate mental health disorders, and none experienced low mental health disorders. Finally, of the 2 respondents with a low sedentary lifestyle, 2 people (100.0%) experienced low mental health disorders. …”
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