Profiling gene alterations in striatonigral neurons associated with incubation of methamphetamine craving by cholera toxin subunit B-based fluorescence-activated cell sorting by Rachel D. Altshuler, Megan A. M. Burke, Kristine T. Garcia, Kenneth Class, Raffaello Cimbro, Xuan Li, Xuan Li

“…On abstinence day 1 or day 28, we collected the DS tissue from both groups for subsequent FACS and examined gene expressions in CTb-positive (striatonigral MSNs) and CTb-negative (primarily non-striatonigral MSNs). Finally, we examined gene expressions in DS homogenates, to demonstrate cell-type specificity of gene alterations observed on abstinence day 28.ResultsOn abstinence day 1, we found mRNA expression of Gabrb3 decreased only in CTb-positive (but not CTb-negative) neurons of Meth rats compared with saline rats, while mRNA expression of Usp7 decreased in all sorted DS neurons. …”
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Safety Assessment of Ship Collision with Piers under the Protection of Anti-Collision Floating Box Based on BIM Technology by Ying-hao Chen, Cheng Liu, Xue-feng Zhao, Fa-xiong Li

“…At the same time, multi-condition analysis was carried out on the ship impacting the pier anti-collision floating box at different angles, different tonnages, and different speeds. Finally, the analysis results are traced back to the BIM model, achieving the unified integration of BIM model information and finite element analysis results and the purpose of visual analysis of any working conditions. …”
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Valores sociales y promoción turística: la Comarca Minera del Mar Menor (España) by Onésimo Samuel Hernández Gómez, Antonio Raúl Fernández Rincón, Pedro Antonio Hellín Ortuño

“…A partir de 1950 se incorporan valores como tecnología, modernidad y desarrollo económico. A finales de 1960 y principios de los años 70 toman protagonismo valores relacionados con la calidad, el ocio, el lujo y el deseo. …”
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Continuous Improvements and Future Challenges of Air Pollution Control at an Advanced Semiconductor Fab by Hsueh-Hsing Lu, Ming-Chun Lu, Thi-Cuc Le, Zhiping An, David Y. H. Pui, Chuen-Jinn Tsai

“…The challenges to removing derived fine PM and white smoke still remain which can be resolved by using efficient control devices in the pre- and post-treatment stages, such as wet electrostatic precipitators. Finally, the by-product NOx can be minimized by using low-NOx burners or de-NOx control technologies in the future.…”
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Observation of food habits and awareness level of students studying at the School of Physical Education and Sports by Harun Akyol, Metin Bayram, Gokhan Bayraktar, Erdogan Tozoglu

“…In respect of information resources of nutrition and nutrition awareness before and after training, significant relations have been uncovered about awareness of the relation between awareness of level of daily energy need, awareness and way of nutrition habits before and after training and success in sports. Finally, no significant variance has been detected between the nutrition awareness levels of the students at Coaching Department and the ones at Sport Teaching Department in some issues. …”
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The AMPK–mTOR Pathway Is Inhibited by Chaihu Shugan Powder, Which Relieves Nonalcoholic Steatohepatitis by Suppressing Autophagic Ferroptosis by Zheng Liang, Dajin Pi, Jianwei Zhen, Haizhen Yan, Chuiyang Zheng, July Liang Chen, Wen Fan, Qingliang Song, Jinyue Pan, Dongdong Liu, Maoxing Pan, Qinhe Yang, Yupei Zhang

“…The liver protein levels of Adenosine monophosphate-activated protein kinase–mammalian target of rapamycin (AMPK–mTOR)-mediated autophagy and ferroptosis markers, such as p-AMPKα/AMPKα, p-mTOR/mTOR, Beclin-1, microtubule associated protein 1 light chain 3 gamma (LC3), p62 (sequestosome 1 [SQSTM1/p62]), Kelch-like ECH-associated protein 1 (KEAP1), nuclear factor erythroid 2-related factor 2 (Nrf-2), ferritin heavy chain 1 (FTH1), and glutathione peroxidase 4 (GPX4), were restored by CSP. …”
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Severe pneumonia due to concurrent Legionella pneumophila and Acinetobacter baumannii infections: a case report by Xiaoming Yang, Zhongda Liu, Xiaojing Liu, Quan Li, Hui Huang, Yibo Wei, Tao Sun

“…However, his condition deteriorated very rapidly, and he required endotracheal intubation and mechanical ventilation for respiratory support. Finally, metagenomic next-generation sequencing (mNGS) of his bronchoalveolar lavage fluid identified L. pneumophila and A. baumannii. …”
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Co-optimising frequency-containment services from zero-carbon sources in electricity grids dominated by Renewable Energy Sources by Aimon Mirza Baig, Luis Badesa, Yi Wang, Goran Strbac

“…The results demonstrate that ancillary services costs can be reduced from 35% to 3.3% and 45% to 4.2% of the total system operating cost under wind scenarios of 70GW and 100GW respectively. Similarly, simulations demonstrate that the provision of ancillary services can significantly reduce emissions in the system.…”
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Fabrication of antibacterial bio‐composite from polyvinyl alcohol incorporated with Azadirachta indica by Md. Tanvir Hossain, Md. Abdus Shahid

“…Moreover, PNBC has a Tg of 84°C, a pyrolysis temperature of 266°C, and degrades between 230 and 400°C, as shown by DSC and TGA. Finally, the results of this experiment were compared with available literature and a cost analysis was conducted. …”
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Oocyte transcriptomes and follicular fluid proteomics of ovine atretic follicles reveal the underlying mechanisms of oocyte degeneration by Yukun Song, Erhan Hai, Nan Zhang, Yu Zhang, Junlan Wang, Xitong Han, Jiaxin Zhang

“…Additionally, we uncovered 333 differentially expressed proteins that may coordinate follicular atresia and revealed key pathways, such as negative regulation of angiogenesis, metabolic pathways, and transcription and mRNA splicing, that lead to oocyte degeneration. Finally, by combining transcriptome and proteomics analyses, we identified two oocyte-secreted biomarkers, PGK1 and ANGPT2, that may be associated with follicular atresia. …”
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Dynamic Coupling Analysis of Vehicle-Bridge System for Long-Span Suspension Bridge Based on Backpropagation Neural Network Method by Zuolong Luo, Xiaobo Zheng, Haoyun Yuan, Xirong Niu

“…It is shown through a numerical example that, compared with FEM, the proposed method is much more economical to achieve reasonable accuracy when dealing with the dynamic coupling problem of the vehicle-bridge system. Finally, an engineering case involving a detailed finite element model of a long-span suspension bridge with a main span of 1688 m is presented to demonstrate the applicability and efficiency under the premise of ensuring the approximation accuracy, which indicates that the proposed method provides a new approach for dynamic coupling analysis of the vehicle-bridge system of long-span suspension bridges.…”
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A Reliable Medium for Monitoring Atmospheric Deposition near Emission Sources by Using Snow from Agricultural Areas by Jiayang Liu, Zaijin Sun, Wenkai Lei, Jingwen Xu, Qian Sun, Zhicheng Shen, Yixuan Lyu, Huading Shi, Ying Zhou, Lan Zhang, Zefeng Wu, Yuepeng Pan

“…Finally, a positive correlation was found between the cadmium content in the snow and the production capacity (<i>R</i>² = 0.90, <i>p</i> < 0.05) and total permitted emissions (<i>R</i>² = 0.69, <i>p</i> > 0.05) of the nearby factories. …”
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Ámbitos de conflicto y repertorios de violencia en el Suroccidente Colombiano by Carlos Enrique Moreno León

“…Se puede concluir que a finales del siglo xx, las fuerzas en confrontación convergen en ciertos territorios que los hacen centrales en la dinámica de la guerra misma. …”
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Preoperative Neutrophil-to-Lymphocyte Ratio, Platelet-to-Lymphocyte Ratio, and CEA as the Potential Prognostic Biomarkers for Colorectal Cancer by Fu Ming-Sheng, Du Mei-Ling, Cai Xun-Quan, Hu Yuan-Xin, Zhang Wei-Jie, Pan Qin-Cong

“…A total of 330 patients were finally included in the current study. The mean follow-up duration was 32.8 ± 19.1 months (range, 0.1–67.7). …”
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A comprehensive pan-cancer analysis of RNF187 in human tumors by Xuezhong Zhang, Xuebin Zhang, Tonggang Liu, Kaihui Sha

“…The findings highlighted associations between RNF187 expression and Tumor Mutational Burden (TMB), Microsatellite Instability (MSI) and Homologous Recombination Deficiency (HRD) in specific tumors. Finally, RNF187 showed a significant positive association with five genes (ALKBH4, FAM134A, MLST8, SANP47 and TMEM9) across the majority of tumors. …”
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Isotherms and Kinetic Studies of Copper Removal from Textile Wastewater and Aqueous Solution Using Powdered Banana Peel Waste as an Adsorbent in Batch Adsorption Systems by Momina Seleman, Takele Sime, Abate Ayele, Assefa Sergawie, Thabo Nkambule, Jemal Fito

“…The kinetics of copper (II) adsorption followed the second-order kinetic model better. Finally, these studies showed that banana peel bio-adsorbent is a potential adsorbent for heavy metal removal from synthetic and textile wastewater.…”
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Feasibility and acceptability of multiple methods of recording injecting drug use episode data among people who inject drugs in Melbourne, Australia: a pilot evaluation study proto... by Alexis Roth, Peter Higgs, Paul Dietze, Nick Scott, Daniel O’Keefe, Filip Djordjevic, Ashleigh Cara Stewart, Dylan Vella-Horne, Zoe Gleeson, Damian Pavlyshyn, Matthew Gill, Rebekka Petrovic, Ben Cocchiaro

“…These multiple data sources will be combined to conduct a comprehensive analysis of the physiological and risk characteristics of an estimated 800 individual injecting drug use episodes (if participants inject four times weekly). Finally, post-participation qualitative interviews will explore the acceptability of the data collection methods.Ethics and dissemination Ethics approval for ITM-Ex was obtained from Alfred Hospital Ethics Committee (project number 368/22). …”
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Biodiversity Change in Cultural Landscapes—The Rural Hotspot Hypothesis by Carsten Neumann, Robert Behling, Gabriele Weiss

“…Spatiotemporal dimensions of backyard pressures involving material fluxes, species exchange and retention, alternation of site conditions, and local genetic adaptation are delineated for different backyard features, including building structures, gardens, lawns, and paved grounds. Finally, we propose a future research agenda to quantify effects and trends of rural hotspots and followed patterns of altered species dynamics. …”
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Colorectal cancer detection with enhanced precision using a hybrid supervised and unsupervised learning approach by Akella S. Narasimha Raju, K. Venkatesh, Ranjith Kumar Gatla, Eswara Prasad Konakalla, Marwa M. Eid, Nataliia Titova, Sherif S. M. Ghoneim, Ramy N. R. Ghaly

“…The hybrid schema of this work treats the deficiencies of the previous approaches, such as incorporating CNN-based effective feature extraction, Transformer networks for developing attention mechanisms, and finally the fine decision boundary of the support vector machine. …”
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Temporal trends and future projections of incidence rate and mortality for asthma in China: an analysis of the Global Burden of Disease Study 2021 by Xi Chen, Xi Chen, Dandan Ma, Hangyu Li, Yilin Liu, Guixing Xu, Xinyu Deng, Qi Li, Junqi Li, Hui Pan

“…The age-period-cohort model was applied to estimate the effects of the age, period, and cohort on the incidence and mortality. Finally, future asthma trends for the next 25 years were predicted utilizing the Bayesian age-period-cohort (BAPC) model.ResultsOver the past three decades, the incidence rate declined in waves while the mortality declined steadily. …”
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