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26721
Clinical efficacy of a virtual reality tool for the treatment of obesity: study protocol of a randomised controlled trial
Published 2022-06-01“…Readiness to change, BMI, eating habits and physical activity, psychological well-being, body image satisfaction, quality of life in relation to body image, and weight bias internalisation will be assessed at baseline, post intervention, 1-week and 4-week follow-up. Finally, variables related to adherence and satisfaction with the VR tool will be evaluated for the experimental groups.Ethics and dissemination This study was approved by the Research Projects Committee of the Vall d’Hebron University Hospital. …”
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26722
An optimized deep-forest algorithm using a modified differential evolution optimization algorithm: A case of host-pathogen protein-protein interaction prediction
Published 2025-01-01“…Additionally, the optimized model predicted seven novel host-pathogen interactions. Finally, the model was implemented as a web application which is accessible at http://dfh3pi.covenantuniversity.edu.ng.…”
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26723
Improvement in the Flux Uniformity of the Solar Dish Concentrator System through a Concave Quartz Window
Published 2020-01-01“…Obviously, the concave quartz window was better than the plane quartz window in improving the flux uniformity. Finally, a further study on the sinusoidal quartz window scheme of all of the above optimal parameter schemes showed that when the installation position of the receiver relative to the dish concentrator was changed, the flux uniformity of the receiver could continue to improve. …”
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26724
Combined anti-leukemic effect of gilteritinib and GSK-J4 in FLT3-ITD+ acute myeloid leukemia
Published 2025-02-01“…Gilteritinib treats acute myeloid leukemia (AML) with the FMS-like receptor tyrosine kinase-3 (FLT3) internal tandem duplication (ITD) mutation. …”
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26725
Direct engulfment of synapses by overactivated microglia due to cadmium exposure and the protective role of Nrf2
Published 2025-01-01“…We also created Nrf2 knockdown (KD) BV2 microglia to investigate the role of cell-specific Nrf2 in Cd-induced microglial activation. Finally, we developed co-culture systems of either Nrf2-KD or Scramble microglia and primary neurons or HT22 neurons to study the effects of Nrf2-regulated microglial activation on synaptic damages induced by Cd. …”
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26726
Advanced process control in laser-based powder bed fusion–Smart Fusion feedback-loop control as a path to uniform properties for complex structures?
Published 2025-01-01“…In MS1, the open-loop lead to signs of in-situ precipitation resulting in a significant local hardness increase in comparison to the feedback-loop control. Finally, the complex MS1 part could be built without minimum exposure times and uniform hardness of 350 HV0.5.…”
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26727
A Structural Comparison between the Origin-Destination Matrices Based on Local Windows with Socioeconomic, Land-Use, and Population Characteristics
Published 2021-01-01“…It is capable of better determining the SSIM of sparse OD matrices by up to 8% compared with the GSSI method. Finally, the sensitivity analysis results indicate that the suggested method is robust and reliable since it is sensitive to applying both constant and random coefficients.…”
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26728
Access to Diagnostics and Treatment for People With Metastatic EGFR-Positive NSCLC: Lessons From Project PRIORITY
Published 2025-03-01“…In addition, 89% reported receiving at least one tyrosine kinase inhibitor (TKI); osimertinib was the most prescribed first-line TKI for stage IV participants diagnosed after 2017. …”
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26729
Hyperinsulinemia Induced Altered Insulin Signaling Pathway in Muscle of High Fat- and Carbohydrate-Fed Rats: Effect of Exercise
Published 2021-01-01“…Exercise significantly upregulated phosphoinositide 3 kinase (PI3K) docking site phosphorylation and downregulated the negative IRS1 phosphorylations thereby increasing the glucose transporter (GLUT) expressions and reducing the lactate accumulation. …”
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26730
Alumina-enriched sunflower bio-oil in machining of Hastelloy C-276: a fuzzy Mamdani model-aided sustainable manufacturing paradigm
Published 2024-11-01“…Besides, the utilization of 0.6 vol% Alumina-sunflower bio-oil has demonstrated a reduction of 17.86% in total machining cost, along with reductions of 15.44% in energy consumption and carbon emissions, when compared to dry machining. Finally, a Taguchi-designed experiment consisting of sixteen trials was performed in different lubricating conditions, and a Fuzzy-Mamdani model was employed to achieve a sustainable machining environment. …”
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26731
Validation of deep-learning accelerated quantitative susceptibility mapping for deep brain nuclei
Published 2025-01-01“…QSM values from 7 deep brain nuclei were extracted and agreements between images with different Afs were assessed. Finally, the correlations between age and QSM values in the selected deep brain nuclei were evaluated.Results59 participants were recruited. …”
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26732
Relationship of modifiable risk factors with the incidence of thyroid cancer: a worldwide study
Published 2025-01-01“…Pearson correlation coefficient was used to evaluate the correlation. Finally, statistical modeling was done using Generalized Additive Model (GAM). …”
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26733
Advances in therapies using mesenchymal stem cells and their exosomes for treatment of peripheral nerve injury: state of the art and future perspectives
Published 2025-11-01“…Subsequently, it provides an overview of the current status of mesenchymal stem cell and exosome-based therapies in clinical trials, followed by a comparative analysis of therapies utilizing mesenchymal stem cells and exosomes. Finally, the review addresses the limitations and challenges associated with use of mesenchymal stem cell–derived exosomes, offering potential solutions and guiding future directions.…”
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26734
Human Action Recognition Using Difference of Gaussian and Difference of Wavelet
Published 2023-09-01“…Linear Discriminant Analysis (LDA), a widely used dimensionality reduction technique, is also used to eliminate duplicate data. Finally, a closest neighbor method is used to classify the dataset. …”
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26735
Prognostic significance of CDK1 expression in diffuse large B-Cell lymphoma
Published 2025-01-01“…Previous studies have found that cyclin-dependent kinase 1(CDK1) are related to tumor growth and metastasis. …”
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26736
Recovery process of patients with iliac vein compression syndrome after stenting: a grounded theory study
Published 2025-01-01“…The stages were (1) exacerbation—worsening symptoms that disrupt daily life, compelling the patient to finally address the issue; (2) seeking help—medical professional help sought; (3) despondency—ongoing pain and recurring symptoms after surgery; (4) adjustment—self-directed health promotion with support systems aiding in recovery; and (5) health preservation—suitable health care and beneficial exercise habit development. …”
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26737
Deciphering mixed infections by plant RNA virus and reconstructing complete genomes simultaneously present within-host.
Published 2025-01-01“…To this end, we tested different sequencing strategies, and we finally combined direct cDNA ONT (Oxford Nanopore Technology) sequencing with the bioinformatics tool RVhaplo. …”
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26738
Multilevel Assessment of Exercise Fatigue Utilizing Multiple Attention and Convolution Network (MACNet) Based on Surface Electromyography
Published 2025-01-01“…MACNet is developed to assess sEMG fatigue, incorporating improved temporal attention based on sliding window, multiscale convolution, and channel-spatial attention. Finally, GradCAM visualization is used to verify the developed model’s interpretation, exploring the effects of sEMG channels and time-domain characteristics on exercise fatigue. …”
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26739
The Economic Succession Doctrine in Private Enforcement of EU Competition Law: 'Nothing Extraordinary' After Skanska Industrial?
Published 2019-10-01“…Secondly, the limits of the economic succession doctrine remain unclear: it is unclear when a corporate restructuring indeed leads to the establishment of a “new” undertaking, free from the antitrust liability acquired by its predecessor. Finally, it remains unclear whether Skanska Industrial case law could also be extended to other remedies besides damage claims, such as actions requesting a court injunction, compensation for unjust enrichment, or a declaration that a contract is null and void. …”
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26740
Shionone Inhibits Glomerular Fibirosis by Suppressing NLRP3 Related Inflammasome though SESN2-NRF2/HO-1 Pathway
Published 2025-01-01“…Results The results demonstrated that SH effectively suppressed glomerular fibrosis, induced adenosine monophosphate-activated protein kinase (AMPK) phosphorylation, and inhibited NLR family pyrin domain containing 3 (NLRP3) activation. …”
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