Preventing and addressing youth vaping in British Columbia, Canada: Evidence from triangulation of a scoping review of vaping policy and qualitative interviews with school-aged you... by Ramona H. Sharma, Sarah J. Dow-Fleisner, Laura L. Struik

“…The interviews, conducted in 2020 and 2021 in the Okanagan region of British Columbia, were analyzed using NVivo software through conventional content analysis, an inductive approach where two coders collaboratively identified categories and sub-categories from participant responses using a finalized codebook. Results: The policy review identified gaps in comprehensiveness, public accessibility, and enforcement, particularly at regional levels, where policies often lack comprehensiveness and fail to address vaping-specific challenges. …”
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Commonality of Virulence-Promoting Function in Rhodococcus equi Virulence Associated Proteins (Vaps) by Timothy R. Ganderton, Daniel Ghete, Karen Hogg, Graeme J. Park, Christoph G. Baumann, Anthony J. Wilkinson, Paul R. Pryor

“…There was a differential activity across these virulence-promoting Vaps with the most “acid-neutralising” activity found with VapN, then VapA and K, and finally VapB. These data suggest that VapA production, which is often found in equine infections, can be substituted by VapK and B (produced by plasmids often found in porcine species) or VapN (produced by plasmids often isolated in bovine and human samples). …”
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Vegetation height estimation based on machine learning model driven by multi-source data in Eurasian temperate grassland by Wuhua Wang, Jiakui Tang, Na Zhang, Xuefeng Xu, Anan Zhang, Yanjiao Wang, Kaihui Li, Yidan Wang

“…The first Eurasian temperate grassland vegetation height dataset was finally generated. The results highlighted the superior performance of the Random Forest with an R2 of 0.54, RMSE of 7.39 cm, and MPAE of 49.25 %. …”
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A microstructure-based numerical approach for uniaxial fatigue life-based non-uniaxial fatigue life prediction of hypo-eutectoid steels by Jonghoon Shin, Hyunki Kim, Minwoo Kang, Chungan Lee, Seunghyun Hong, Yoon Suk Choi

“…The proposed prediction procedure involves the generation of a statistically representative synthetic microstructure, the development of slip system-based fatigue constitutive models for the primary ferrite and pearlite phases constituting the hypo-eutectoid steel, the synthetic microstructure-based finite element simulations for uniaxial, torsional, and in-phase and out-of-phase axial plus torsional fatigue loading conditions using the developed constitutive models, the extraction of the cyclic increment of the fatigue indicator parameters (ΔFIP) from fatigue-simulated microstructures for the local fatigue damage quantification, the calibration of the uniaxial fatigue life prediction model by linking simulated uniaxial ΔFIPs to the uniaxial fatigue life data, and finally the prediction of the non-uniaxial fatigue life (through simulated non-uniaxial ΔFIPs) using the uniaxial fatigue-calibrated life prediction model. …”
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Association of calf circumference with osteoporosis and hip fracture in middle-aged and older adults: a secondary analysis by Mumin Cao, Yuanwei Zhang, Mengze Tong, Xiangxu Chen, Ziang Xu, Renwang Sheng, Liu Shi, Cheng Zhang, Wenbin Fan, Tian Xie, Yingjuan Li, Jinyu Wang, Wei Gao, Yunfeng Rui

“…The receiver operating characteristic (ROC) curve was utilized to determine the optimal cut-off value for CC. Finally, logistic regression model analysis was applied to test the predictive efficacy of CC. …”
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Latin America in the 21st Century: Regional Development Trajectories by D. A. Kuznetsov

“…The second implies civilizational ‘isolation’ of LAC within large but still only regional integration projects. Finally, the third scenario proceeds from the linear development of the current regional trends. …”
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Uplift Test and Design Method for Bearing Capacity of Isolated Spread Concrete Foundation Slab with Large Width-to-Height Ratio by Yuanqi Li, Xiaoliang Qin, Jinhui Luo, Meng Xiao, Cong Hua

“…To obtain the suggested design method of uplift capacity for the foundation slab, effective width correction coefficient k and slope correction coefficient j were introduced to propose a design formula. Finally, the proposed design method was applied to a practical engineering, and the economic indicators obtained from the suggested design method were compared with that from the original design method. …”
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The sow vaginal and gut microbiota associated with longevity and reproductive performance by Ziyu Liu, Tsungcheng Tsai, Bin Zuo, Samantha Howe, Jason E. Farrar, Christopher E. Randolph, Charles V. Maxwell, Jiangchao Zhao

“…Furthermore, sows in the U4P group with longevity potential also showed better reproductive performance. Finally, we discovered bacterial predictors (e.g., Prevotellaceae NK3B31 group) for the total number of piglets born throughout the four parities in both the rectum and vagina. …”
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An Update Review to Cast Light on the Possible Role of Altered Oropharyngeal Microbiota in Differentiating True Psychosis from Malingered Psychosis in a Forensic Psychiatric Settin... by Mohsen Khosravi, Domenico De Berardis, Sahel Sarabandi, Sakineh Mazloom, Amir Adibi, Negin Javan, Zahra Ghiasi, Mohammad Nafeli, Negar Rahmanian

“…As per the systematic search terms (namely, “diagnostic marker,” “oropharyngeal microbiome,” “forensic psychiatric setting,” “psychosis,” and “oropharyngeal microbiota”), relevant English publications were searched from January 1, 1980, to September 15, 2023, in Scopus, the Web of Science, Embase, Cochrane Library, PubMed, and Google Scholar databases. Finally, eight articles were included in the present review. …”
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Performance evaluation of organizational units with the hybrid approach of intuitionistic fuzzy DEMATEL-ELECTRE by Maryam Daneshvar, Fatemeh Karimi Jafari, Zahra Moradi Golriz

“…First, the performance indicators have been determined by the literature review and consulting experts, and then the importance and weight of each of the performance indicators has been calculated using the intuitionistic Fuzzy DEMATEL and finally, the performance of organization's units has been evaluated using the ELECTRE intuitionistic Fuzzy method. …”
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Relationship between inherited genetic variation and survival from colorectal cancer stratified by tumour location by Christopher Wills, Katie Watts, Amy Houseman, Timothy S. Maughan, David Fisher, Nada A. Al-Tassan, Richard S. Houlston, Valentina Escott-Price, Jeremy P. Cheadle

“…We investigated the relationship between Phosphatidylinositol 4-Kinase Type 2 Beta (PI4K2B) expression in colorectal tumours and survival in 597 patients from The Human Protein Atlas (THPA). …”
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Evaluation of hygienic food handling practices and associated factors among food handlers in the Amhara region, Ethiopia: a systematic review and meta-analysis by Lamenew Fenta, Kebadu Tadesse

“…Data was collected and entered into Excel and finally exported to Stata V.17 for analysis. Eyeball testing using forest plots, Cochrane Q test statistics and I² had been used to identify and measure heterogeneity. …”
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Expression of Leptin Receptor and Effects of Leptin on Papillary Thyroid Carcinoma Cells by Marilena Celano, Valentina Maggisano, Saverio Massimo Lepore, Marialuisa Sponziello, Valeria Pecce, Antonella Verrienti, Cosimo Durante, Marianna Maranghi, Piernatale Lucia, Stefania Bulotta, Giuseppe Damante, Diego Russo

“…In this translational study, we analyzed in vitro the effects of leptin on the growth and migration of thyroid cancer cells (TPC-1 and K1), the molecular mechanisms underlying leptin’s action, and the influence of prolonged leptin exposure on cell response to a protein kinase inhibitor lenvatinib. The expression levels of OB-R mRNA and protein were also investigated in vivo in a series of aggressive PTCs divided into two groups based on the presence of the BRAF mutation. …”
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Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs by Khushboo Agrawal, Viswanath Das, Natálie Táborská, Ján Gurský, Petr Džubák, Marián Hajdúch

“…In contrast, the conditioned medium from senescent fibroblasts that upregulated NF-κB activity altered deoxycytidine kinase levels in drug-untreated CRC cells and abrogated DAC effect on degradation of DNA methyltransferase 1. …”
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Diversity in Notch ligand-receptor signaling interactions by Rachael Kuintzle, Leah A Santat, Michael B Elowitz

“…Lfng strengthened Delta-mediated trans-activation and weakened Jagged-mediated trans-activation for both receptors. Finally, cis-ligands showed diverse cis-inhibition strengths, which depended on the identity of the trans-ligand as well as the receptor. …”
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Fatigue life prediction of asphalt binders under variable loading levels based on dissipated pseudo-strain energy by Chenze Fang, Hui Li, Zhenxia Li, Yuanzhao Chen, Tengteng Guo

“…Furthermore, the evolution law and increment process of fatigue damage for the tested binders were analyzed using the fatigue damage characterized by dissipated pseudo-strain energy (DPSE). Finally, a binder fatigue life prediction model considering the sequence and interaction of variable loading levels according to damage equivalent criterion. …”
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Impact of Organic Agriculture on the Quality of Grapes (Syrah and Tempranillo) Harvested in Guanajuato, Mexico: Relationship Between Soil Elemental Profile and Grape Bioactive Prop... by Fabio Macías-Gallardo, Tannia Alexandra Quiñones-Muñoz, Raúl Miranda-Avilés, Luis Felipe Ramírez-Santoyo, Gabriela Ana Zanor, César Ozuna

“…The second component showed positive correlations between OM, silt, soil oxides, antioxidant capacity, and phenols in grape skin and seed. Finally, the edaphic conditions of the ORG vineyard allowed for one to obtain optimal grapes for winemaking due to their higher phenol content.…”
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Study of the Feasibility of Regeneration of Central Worn-Out Textures of Ilam City Based on Urban Smart Growth Approach by pakzad azadkhani, mohammad Salavarzizadeh, Fatemeh Farogh Doost

“…Evaluation of the digital strata shows that some indicators (including size of the sections, access to services, main and secondary access points) are in a good condition and others (including unused land, population density, gender ratios, active population, employment rate, and literacy rate) are in a poor condition. Finally, the results show that 2.3 hectares of the worn-out texture of Ilam City, including 22-Bahman Square, Ashrafi Esfahani St. where it crosses Resalat Intersection, the northern edge of Moghavemat Intersection, the northern edge of Imam Square, and the area around Koudak Park, have the highest priority for regeneration and revitalization.…”
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Default mode network-basal ganglia network connectivity predicts the transition to postherpetic neuralgia by Ying Wu, Chao Wang, Wei Qian, Lieju Wang, Lina Yu, Minming Zhang, Min Yan

“…Moreover, DMN-BGN connectivity was associated with the ID pain score in patients with AHZ. Finally, the DMN-BGN connectivity of AHZ patients could predict the outcome of HZ patients with sensitivity and specificity of 77.8 % and 63.2 %, respectively. …”
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Mechanistic insights into Rho/MRTF inhibition-induced apoptotic events and prevention of drug resistance in melanoma: implications for the involvement of pirin by Bardees M. Foda, Bardees M. Foda, Annika E. Baker, Annika E. Baker, Annika E. Baker, Łukasz Joachimiak, Marzena Mazur, Richard R. Neubig, Richard R. Neubig, Richard R. Neubig

“…The effects of CCG-257081 on proliferation (Ki67) and caspase-3 activation were assessed in resistant YUMMER_R tumors in vivo. Finally, two CCG-257081 enantiomers were tested for pirin binding, inhibition of the Rho/MRTF-mediated activation of ACTA2 gene expression in fibroblasts, and the prevention of Vem resistance development by YUMMER_P cells.ResultsVem reduced growth of parental but not resistant cells, while CCG-257081 inhibited both. …”
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