An In silico Approach towards Finding the Cancer-Causing Mutations in Human MET Gene by Fayeza Sadia Laskar, Md. Nazmul Islam Bappy, Md. Sowrov Hossain, Zenifer Alam, Dilruba Afrin, Sudeb Saha, Kazi Md. Ali Zinnah

“…Mesenchymal–epithelial transition (MET) factor is a proto-oncogene encoding tyrosine kinase receptor with hepatocyte growth factor (HGF) or scatter factor (SF). …”
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Multiple Assessments on the Gamma-Ray Protection Properties of Niobium-Doped Borotellurite Glasses: A Wide Range Investigation Using Monte Carlo Simulations by H. O. Tekin, Fatema T. Ali, Ghada Almisned, Gulfem Susoy, Shams A. M. Issa, Antoaneta Ene, Wiam Elshami, Hesham M. H. Zakaly

“…However, the replacement of 2% moles of Nb2O5 with 1% mole of Ta2O5 and 1% mole of ZrO2 provided significant improvements in both glass density and attenuation properties against gamma rays. Finally, the HVL values of the S3 sample were compared with some glass- and concrete-shielding materials and the S3 sample was reported for its outstanding properties. …”
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Effort-reward imbalance and health outcomes in emergency nurses: the mediating role of work–family conflict and intrinsic effort by Le Tong, Le Tong, Ling Zhu, Ling Zhu, Hao Zhang, Hao Zhang, Luying Zhong, Luying Zhong, Dongmei Diao, Dongmei Diao, Xiaoli Chen, Xiaoli Chen, Jianna Zhang, Jianna Zhang

“…Statistical analyses, including mediation and moderation, were performed using the PROCESS macro to evaluate the relationships between the variables.ResultsIn this study, 1,540 emergency nurses were finally included. The analysis revealed that 80.5% of participants reported experiencing effort-reward imbalance, which was significantly associated with increased somatic symptoms and mental symptoms. …”
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تولية الكافر على المسلم في ولاية الحكم عند ابن تيمية by Ahmad Muqorobin, Ahmad Rayhan

“…The reality is very difficult to find the ideal leader figure, until finally many discourses that say that the leader is not important Muslims or infidels. …”
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Sulforaphane Ameliorates the Intestinal Injury in Necrotizing Enterocolitis by Regulating the PI3K/Akt/GSK-3β Signaling Pathway by Zhong-Kun Bao, Yan-Hong Mi, Xiao-Yu Xiong, Xin-Hong Wang

“…IEC-6 and FHC cells were induced with LPS to mimic NEC in vitro and coincubated with SFN; then, the inflammatory factor levels and cell apoptosis rate were detected. Finally, Western blot was used to assess the expression of PI3K/Akt/GSK-3β pathway-related proteins in vitro and in vivo. …”
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Tensions within the British Conservative Party in the Context of Brexit by R. I. Blagoveshchenskii

“…The third group fully supports T. May’s policy. And, finally, the fourth faction opposes the very idea of Brexit and backs for the second Brexit referendum. …”
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ATP Induces Disruption of Tight Junction Proteins via IL-1 Beta-Dependent MMP-9 Activation of Human Blood-Brain Barrier In Vitro by Fuxing Yang, Kai Zhao, Xiufeng Zhang, Jun Zhang, Bainan Xu

“…Degradation of tight junction proteins (TJPs) such as ZO-1 and occludin occurs, which finally contributes to disruption of BBB. A contact coculture system using human astrocytes and hCMEC/D3, an immortalized human brain endothelial cell line, was used to mimic BBB in vitro. …”
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Drawing-Aware Parkinson’s Disease Detection Through Hierarchical Deep Learning Models by Ioannis Kansizoglou, Konstantinos A. Tsintotas, Daniel Bratanov, Antonios Gasteratos

“…By directly comparing it against a similar end-to-end classifier, the benefits of our technique are clearly illustrated during experiments. Finally, its performance is compared against several state-of-the-art ML- and DL-based PD detection methods, demonstrating the method’s supremacy.…”
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Sustainability by extraction of bioactive compounds from onion seeds by Mestour, Selma, Meniai, Abdeslam-Hassen, Melloul, Sarra, Louaer, Mehdi

“…These fatty acids are well known for their benefits for human health. Finally this research showed ability of the supercritical CO2 extraction to induce a sustainability character while being performing in producing bioactive substances, excluding the use of organic solvent and even replacing classical and traditional techniques like hydrodistillation.…”
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Bioadhesive Chitosan Films Loading Curcumin for Safe and Effective Skin Cancer Topical Treatment by Seila Tolentino, Mylene M. Monteiro, Felipe Saldanha-Araújo, Marcilio Cunha-Filho, Tais Gratieri, Eliete N. Silva Guerra, Guilherme M. Gelfuso

“…Furthermore, curcumin alone was more effective in inhibiting tumor cells than radiotherapy alone (<i>p</i> < 0.01), with no additional benefit observed when curcumin was combined with radiotherapy. Finally, irritation tests confirmed that the films were safe for topical application. …”
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Multi-Layer Perceptron Model Integrating Multi-Head Attention and Gating Mechanism for Global Navigation Satellite System Positioning Error Estimation by Xiuxun Liu, Zuping Tang, Jiaolong Wei

“…The data are then preprocessed to extract available features. Finally, the features are input into the constructed model for training and testing to obtain the estimated positioning error value. …”
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Effects of Ghrelin on Triglyceride Accumulation and Glucose Uptake in Primary Cultured Rat Myoblasts under Palmitic Acid-Induced High Fat Conditions by Lingling Han, Jia Li, Ying Chen, Wei Wang, Dan Zhang, Guoliang Liu

“…The glucose transporter 4 (GLUT4), AMP-activated protein kinase (AMPK), acetyl-CoA carboxylase (ACC), and uncoupling protein 3 (UCP3) were assessed by RT-PCR and western blot. …”
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Typhoon Maria Precipitation Retrieval and Evolution Based on the Infrared Brightness Temperature of the Feng-Yun 4A/Advanced Geosynchronous Radiation Imager by Gen Wang, Kefu Wang, Wei Han, Dongyong Wang, Xuexing Qiu

“…Based on the preliminary experimental “quantification” evaluation index, we concluded that the method adopted in this paper can be used to retrieve precipitation in infrared data and to retrieve the spiral cloud rain bands of a typhoon. Finally, based on the AGRI channel brightness temperature of a 10.8-micron window channel, we applied the membership degree information of a typhoon’s dominant cloud system from the fuzzy c-means (FCM) clustering method to modify precipitation retrieval results. …”
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Collaborative security assessment of cloud-edge-device distributed systems based on order parameters by FAN Qigang, JIANG Zhongyuan, LI Xinghua, MA Jianfeng

“…In this way, the efficient and low-cost collaborative protection of security risks could be realized to maximize systemic security benefits. Finally, the consistency theory and assessment method were verified through simulations. …”
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Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning by Qianqian Liang, Yide Wang, Zheng Li, Zheng Li, Zheng Li, Zheng Li

“…Multiple machine learning algorithms identified 4 shared biomarkers for COPD and diabetes, including CADPS, EDNRB, THBS4 and TMEM27. Finally, the 4 shared biomarkers were validated in single-cell sequencing data, clinical samples, and animal models, and their expression changes were consistent with the results of bioinformatic analysis.ConclusionsThrough comprehensive bioinformatics analysis, we revealed the potential connection between diabetes and COPD, providing a theoretical basis for exploring the common regulatory genes.…”
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Les premiers colons de l’ancienne Haïti et leurs attaches en métropole, à l’aube des premiers établissements (1650-1700) by Philippe Hroděj

“…This population was heterogeneous: from the indentured servant (enlisted to cultivate tobacco or to hunt) to the officer, from the deserter to the settler, to the missionaries, buccaneers, pirates, or privateers, so many originally different lives finally met in America. The ability to move over long distances was extraordinary, and dealing with the Atlantic without evoking the Indian Ocean and the South Sea makes no sense. …”
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Deja vu: Medieval Motifs in Modern Arab Political Life by V. V. Naumkin, V. A. Kuznetsov

“…Major attention is paid to Libyan militias, which are studied on the materials of field research conducted by one of the authors. Finally, the third element discussed is the particular role of the army and other security forces in the Arab political systems.The authors provide three possible interpretations of all the revealed coincidences. …”
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The IclR-family transcriptional regulator XyrR controls flotation, motility, antibiotic production and virulence in Serratia sp. ATCC 39006 by Carlo Miguel Castro Sandoval, Carlo Miguel Castro Sandoval, George P. C. Salmond

“…We also found that the proteins encoded by a putative yagEF-yjhF operon, involved in xylonate catabolism and transport, showed a 5- to 7-fold increase in expression. Finally, we show that IclR is a repressor of xylonate catabolism in S39006 and suggest that xylonate is potentially involved in controlling carbapenem and prodigiosin biosynthesis. …”
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Seismic Performance of Offshore Piers under Wave Impact and Chloride Ion Corrosion Environment by Yin Gu, Anhua Yu, Xiaolong Zhang

“…Then, according to the corrosion characteristics of coastal chloride salts on reinforced concrete bridge piers, the corrosion parameters is selected by Latin hypercube sampling, and the influence of corrosion expansion and cracking of bridge pier cover on the chloride ion corrosion process is considered to modify the degradation model of corroded reinforced concrete materials. Finally, the wave load measured by the test is converted by the similarity criterion of the fluid mechanic test and loaded into the ABAQUS full-bridge model, and the pier after the tsunami wave is evaluated by the pushover analysis. …”
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Random-Parameter Multivariate Negative Binomial Regression for Modeling Impacts of Contributing Factors on the Crash Frequency by Crash Types by Chenzhu Wang, Fei Chen, Jianchuan Cheng, Wu Bo, Ping Zhang, Mingyu Hou, Feng Xiao

“…Subsequently, we compute the goodness-of-fit and predictive measures to confirm the superiority of the proposed model. Finally, we also calculate the elasticity effects to augment the comparison. …”
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