Post-processing enhances protein secondary structure prediction with second order deep learning and embeddings by Sotiris Chatzimiltis, Michalis Agathocleous, Vasilis J. Promponas, Chris Christodoulou

“…In fact, with the biggest post-processing window size (limited by the smallest CASP13 protein), we achieved a Q3 accuracy of 98.12% and a Segment Overlap (SOV) score of 96.98 on the CASP13 dataset when the CNNs were trained with the PISCES dataset. Finally, we showed that input representations from embeddings can perform equally well as representations extracted from multiple sequence alignments.…”
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Outburst mechanism and hazard prevention technique of limestone aquifer under isolated island panels by Wei Wang, Wei Wang, Wei Wang, Yanjun Wu, Yanjun Wu, Yanjun Wu, Yongli Shi, Yongli Shi, Yongli Shi, Jingzhong Zhu

“…The maximum stress of the panel floor is greater than that of mining without isolated islands. (2) The special drilling structures, stepwise gradient pressurization, and segmented sequential downward grouting technique are proposed to ensure the grouting effect under goaf. (3) Finally, the limestone water disaster regional treatment and control for the isolated island shaft is carried out and validated. …”
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New insights into the ferroptosis and immune infiltration in endometriosis: a bioinformatics-based analysis by Lusha Liu, Feifei Han, Naiyi Du, Yakun Liu, Aihong Duan, Shan Kang, Bin Li

“…Consensus cluster analysis identified ferroptosis subclusters, and CIBERSORT assessed immune infiltration of these subclusters. Finally, RT-qPCR validated hub FRG expression in clinical tissues.ResultsWe identified two ferroptosis modules of endometriosis, and by enrichment analysis, they are closely linked with autophagy, mTOR, oxidative stress, and FOXO pathways. …”
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Laser Synthesis of Platinum Single-Atom Catalysts for Hydrogen Evolution Reaction by Hengyi Guo, Lingtao Wang, Xuzhao Liu, Paul Mativenga, Zhu Liu, Andrew G. Thomas

“…The atomically dispersed Pt on the carbon substrate exhibited a small overpotential of 68.8 mV at 10 mA cm⁻² for the hydrogen evolution reaction with a mass activity 20.52 times that of a commercial Pt/C catalyst at an overpotential of 50 mV vs. RHE. Finally, we note that the synthesis method is simple, fast, and versatile, and potentially scalable for the mass production of SACs for electrocatalytic applications.…”
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YOLOv8n-CA: Improved YOLOv8n Model for Tomato Fruit Recognition at Different Stages of Ripeness by Xin Gao, Jieyuan Ding, Ruihong Zhang, Xiaobo Xi

“…The CARAFE up-sampling operator was integrated to expand the receptive field for improved feature fusion. Finally, the SIoU loss function was used to solve the problem of insufficient CIoU of the original loss function. …”
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Numerical analysis model for the instantaneous grinding temperature of face gears with a worm grinding wheel by WANG Chao, GUO Hui, RUAN Yuhang, RAN Xiaoping, ZHAO Ning

“…Subsequently, the generation and transfer of heat during the grinding process were examined, leading to the development of a numerical analysis model for the instantaneous grinding temperature of face gears with a worm grinding wheel. Finally, the proposed model’s computational accuracy was validated through the test of the grinding temperature.ResultsThe analysis results demonstrate that the instantaneous grinding temperature significantly increases from the inner diameter to the outer diameter at a fixed tooth height position. …”
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Exploring target selectivity in designing and identifying PI3Kα inhibitors for triple negative breast cancer with fragment-based and bioisosteric replacement approach by Debojyoti Halder, Shreya Mukherjee, R. S. Jeyaprakash

“…Further, the top 2 moieties – Djh1 and Djh2 were selected after MMGBSA analysis and target selectivity prediction towards kinase. Further induced fit docking (IFD) analysis, DFT analysis, and MD simulation were employed to establish that – Djh1 and Djh2 could act as potential hit molecules for selective inhibition of PI3Kα. …”
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Effect of Magnesium Borates on the Fire-Retarding Properties of Zinc Borates by Azmi Seyhun Kipcak, Nil Baran Acarali, Emek Moroydor Derun, Nurcan Tugrul, Sabriye Piskin

“…Examination of the SEM images indicated that the obtained nanoscale minerals had a reaction efficiency ranging between 63–74% for MB and 87–98% for ZB. Finally, the fire-retarding properties of the synthesised pure MBs, pure ZBs, and mixtures of MB and ZB were determined using differential thermal analysis and thermal gravimetry (DTA-TG) and differential scanning calorimetry (DSC).…”
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Adsorption of Lennard-Jones Fluids in Carbon Slit Pores of a Finite Length. A Computer Simulation Study by A. Wongkoblap, S. Junpirom, D.D. Do

“…The simulation box size was also important, especially at low pressures at which the size must be sufficiently large to have a statistically acceptable number of particles in the bulk phase. Finally, it was found that the Canonical Ensemble and the Gibbs Ensemble both yielded the same isotherm (within statistical error); however, the computation time for GEMC was shorter than that for canonical ensemble simulation. …”
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Explore Knowledge-Sharing Strategy and Evolutionary Mechanism for Integrated Project Team Based on Evolutionary Game Model by Yanchao Du, Hengyu Zhou, Yongbo Yuan, Xiaoxue Liu

“…Then, a replicator dynamic system is established based on payoff matrix, to determine the evolutionary tendency of knowledge-sharing behavior. Finally, numerical simulations are conducted to explore the influences of all parameters on the knowledge-sharing strategy. …”
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Self-other distinction modulates the sense of self-agency during joint actions by Laura Zapparoli, Marika Mariano, Lucia Maria Sacheli, Tommaso Berni, Caterina Negrone, Carlo Toneatto, Eraldo Paulesu

“…Do we explicitly and implicitly feel like we are fully in control of the motor act even if the goal is finally achieved by our partner? To address these questions, we measured explicit and implicit sense of self-agency in individual and (coordinated or sequential) interactive contexts. …”
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Comprehensive Analysis on the Specific Role and Function of Mitochondrial Inner Membrane Protein MPV17 in Liver Hepatocellular Carcinoma by Hanchuan Tao, Cheng Wang, Chongmei Lu, Ning Ma, Yifan Zhu, Shihai Xuan, Xiaojun Zhou

“…Then, MPV17 was analyzed by prognostic model, Cox analysis, predictive nomogram, pathway correlation, and immunoassay. Finally, the functions of MPV17 were determined by CCK-8 and Tranwell assays. …”
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Designing a web-based virtual environment for 3D cadaster by Javad Sadidi, Sabah Motamedi, hani rezayan

“…Then, the trends of 3D visualization developments for older plugin and WebGL based technologies have been considered. Finally, a number of the most important systems according to the needed criteria for web-based 3D cadaster were evaluated and consequently, Cesium virtual environment has been selected as the best for the development purpose. …”
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Identification of Damage in Pear Using Hyperspectral Imaging Technology by Cheng-Tao Su, Bin Li, Hai Yin, Ji-Ping Zou, Feng Zhang, Yan-De Liu

“…The results of the discriminant model show that the discrimination accuracy of the SVM based on R, A, and K-M spectra is higher than that of PLS-DA of them; the A-RAW-SVM model has the best discrimination performance with an overall discrimination accuracy of 100% for the test and 98.98% for calibration sets, respectively. Finally, the spectra were selected by the competitive adaptive reweighted sampling (CARS) and the uninformative variables elimination (UVE) to obtain the characteristic wavelengths, and the SVM models were built based on the filtered R, A, and K-M. …”
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Application of an Internet of Things Oriented Network Education Platform in English Language Teaching by Huizhen Li

“…By analyzing the current situation of the Internet of Things education platform, including its development and structure, this paper constructs the evaluation model of the combination of long-term memory neural network model and gray model and realizes the evaluation of the teaching effect of the Internet of Things education platform. Finally, through the study of the model, the teaching effect of the Internet of Things education platform is evaluated. …”
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Application of Path Analysis in identification of dominant effective meteorological parameters on ET0 in West Azarbaijan by Yagob Dinpashoh, Masoumeh Foroughi

“…Also, it was found that the wind speed at all of stations had a significant correlation (at the 0.01% level) with ET0. …”
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Nonintrusive Load Identification for Industrial Users Integrated with LSQR and Sequential Leader Clustering by Shuhui Yi, Yinglong Diao, Junjie Liu, Tian Fang, Xiaodong Yin

“…The sequential leader clustering algorithm is propounded to classify transient events of typical industrial loads and further identify which kind of loads had switched. Finally, to validate the effectiveness of the presented model, data of industrial loads from a concrete plant are collected, including blender, cement screw, sewage dump, and inclined belt conveyor, and simulation analysis is fulfilled. …”
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International Organizations: the Main Factors of Emergence and Development by L. S. Voronkov

“…The article presents the main factors that in later stages of internationalization and development of contemporary international relations gave the impetus to emergence and development of international organizations, including the military-technological revolution, that gave birth to mass destruction weapons and avalanche-like growth of the number of human and material losses during wars and military conflicts, the Cold War between world communism and world capitalism, the collapse of the colonial system and formation ofa new main contradiction of the world politics between the "Club of rich countries" and states of the "global periphery", beginning of development of regional integration processes and, finally, the emergence of global problems. The article emphasizes that both IIGOs and INGOs evolved from the supportive tools in implementation of multilateral interaction of sovereign states towards becoming an integral part of contemporary international relations, fulfilling many vital functions of modern human society and its citizens. …”
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Skeletal muscle ribosome analysis: A comparison of common assay methods and utilization of a novel RiboAb antibody cocktail by Joshua S. Godwin, J. Max Michel, C. Brooks Mobley, Gustavo A. Nader, Michael D. Roberts

“…., magnitudes of bias) discussed herein. Finally, the RiboAb cocktail may also represent ribosome content, although this should be further explored in other models.…”
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Different functions of PHF10 isoforms – subunits of the PBAF chromatin remodeling complex by A. A. Sheynov, V. V. Tatarskiy, A. M. Azieva, S. G. Georgieva, N. V. Soshnikova

“…All PHF10 isoforms are degraded by β-TrCP ubiquitin ligase but PHF10-S isoforms contain a cluster of serins (X-cluster) for multiple phosphorylation by casein kinase I. This phosphorylation protects the β-TrCP degron from β-TrCP recognition and subsequently stabilizes the PHF10-S isoforms. …”
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