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25801
Prediction of traditional Chinese medicine for diabetes based on the multi-source ensemble method
Published 2025-01-01“…The frequencies of occurrences of medicinal herbs corresponding to these three algorithms are obtained, each containing an active ingredient list. Finally, the frequencies of occurrences of the medicinal herbs obtained from the three algorithms using the component and target datasets are integrated to select duplicate drugs as the candidate drugs for diabetes treatment.ResultsThe identification results reveal that theproposed ensemble method has higher accuracy than GBDT, FNT, and LightGBM. …”
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25802
An optimized lightweight real-time detection network model for IoT embedded devices
Published 2025-01-01“…In addition, it provides a detection frame rate of up to 33 Frames Per Second (FPS), satisfying the real-time requirement. Finally, an intelligent production line system based on FRYOLO is implemented, which not only provides robust technical support for the efficient operation of fruit production processes but also demonstrates the availability of the proposed network model in practical IoT applications.…”
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25803
MicroRNA-219 in the central nervous system: a potential theranostic approach
Published 2024-12-01“…Furthermore, miR-219 also plays a role in modulating tau toxicity, which is relevant to the pathophysiology of Alzheimer’s disease and schizophrenia. Finally, it reportedly has protective effects against seizures and Parkinson’s disease, as well as neoplasms, by inhibiting proliferation, suppressing invasion, and inducing cell death in tumor cells. …”
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25804
Fabrication and characterization of V-doped ZnO films implemented to lead-free piezoelectric micromachined devices
Published 2025-01-01“…The results indicate a piezoelectric coefficient as high as 194.5 pm/V, which is superior to most doped ZnO films. Finally, an experimental testing system is established to examine the p-MUT performance. …”
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25805
Exploration and Analysis of Collaborative Matching Algorithm Empowering Large Data Fiscal Budget
Published 2022-01-01“…Combined with the matching algorithm and linear regression prediction algorithm in data analysis, the financial data is analyzed in depth. Finally, the PSO-SA algorithm runs 10 rounds on the datasets with matching scales d=10 and 30, respectively. …”
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25806
Notas sobre la cosmología disciplinar del Trabajo Social
Published 2016-01-01“…Ello nos permite traducir el sentido histórico de las experiencias singulares, en un texto disciplinar en plena y constante realización, sin coordenadas preestablecidas ni finales prescriptivos. Dicho asunto, representa la reanudación del presente como como confluencia del pasado y rutas de futuro, producto de la acción creadora de los y las Trabajadores y Trabajadoras Sociales en el fructifico espacio de lo social. …”
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25807
In vivo antitumor activity of PHT-427 inhibitor-loaded polymeric nanoparticles in head and neck squamous cell carcinoma
Published 2025-12-01“…The phosphatidylinositol-3-kinase (PI3K) signaling pathway is frequently activated in HNSCC, making it an attractive target for therapies. …”
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25808
Advances in Hemodynamic Analysis in Cardiovascular Diseases Investigation of Energetic Characteristics of Adult and Pediatric Sputnik Left Ventricular Assist Devices during Mock Ci...
Published 2019-01-01“…Furthermore, this study expands the information on LV-LVAD interaction, which leads to the optimization of the RBP speed rate control in clinics for adult and pediatric patients suffering from heart failure. Finally, we show that the implementation of control algorithms using the modulation of the RBP speed in order to open the aortic valve and unload the LV more efficiently is necessary and will be content of further research.…”
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25809
Neuropathology-based approach reveals novel Alzheimer's Disease genes and highlights female-specific pathways and causal links to disrupted lipid metabolism: insights into a viciou...
Published 2025-01-01“…Post-GWAS analyses illuminate the functional and biological mechanisms underlying AD and reveal sex-specific differences. Finally, through PheWAS and Mendelian Randomization analysis, we identify causal links with AD neuropathology pointing to disrupted lipid metabolism, as well as impaired peripheral immune response and liver dysfunction as part of a vicious cycle that fuels neurodegeneration.…”
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25810
Shpet, Humboldt, Kant: Forms, Concepts, Schemes. Terms and Ideas
Published 2024-01-01“…The author also considers Shpet’s critique of subjectivism, which robs subjectivism of creativity and confines it to the capacity to convey what has been understood and to err. Finally, Shpet’s methodology (the question of identity and difference) and the role of terminology in his own works is considered. …”
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25811
Effect of Imatinib on Bone Marrow Morphology and Angiogenesis in Chronic Myeloid Leukemia
Published 2019-01-01“…Imatinib inhibits BCR-ABL tyrosine kinase produced due to reciprocal translocation t(9;22) in neoplastic CML cells. …”
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25812
Accusations and Law Articles Prediction in the Field of Environmental Protection
Published 2024-12-01“…We address data imbalance in this dataset using the text generation capabilities of judicial large models. Finally, EKICAN fuses semantic information from different parts with external knowledge to output prediction results. …”
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25813
Study on the Parameter Optimization and Strength Mechanism of Coal Gangue Emulsified Asphalt Mixture
Published 2020-01-01“…The water stability of coal gangue emulsified asphalt mixture is evaluated by the immersion Marshall test. Finally, the strength formation mechanism of coal gangue emulsified asphalt mixture is analyzed from the microscopic point of view. …”
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25814
Returns to scale in decision-making units with integer-valued or mixed inputs and integer-valued or real outputs using radial models in data envelopment analysis
Published 2023-09-01“…Purpose: The current paper tries to determine the type of returns to scale in a decision-making unit under the condition that integer-valued inputs or outputs are present.Methodology: This paper introduces radial models for determining the value and type of Returns to Scale (RTS) in 4 scenarios, including single integer-valued input – single real output (scenario one), mixed inputs – exclusively real outputs (scenario two), exclusively integer-valued inputs – exclusively real outputs (scenario three), and exclusively integer-valued inputs – exclusively integer-valued outputs (scenario four); in each scenario, the values of the left RTS and right RTS are determined, and the RTS type is then determined on that basis. Finally, by presenting three examples based on two scenarios, namely single integer-valued input – single real output and single integer-valued input – single integer-valued output, the new method is compared with previous methods using GAMS software, and the conclusions are provided.Findings: The type of returns to scale differs when integer-valued inputs or outputs are present as compared with the case where the inputs and outputs are assumed to have real values.Originality/Value: This study focuses on the value and type of returns to scale for integer-valued data. …”
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25815
xCT as a potential marker for neuroendocrine cells in high-risk prostate cancer and the relation to AL122023.1-miR-26a/30d/30e axis.
Published 2025-01-01“…Moreover, immunostaining revealed precise xCT expression in neuroendocrine cells, ranging from fetal, healthy juvenile, and adult prostate tissue to benign prostatic hyperplasia and finally advanced prostate cancer. This study explores the relevance and function of xCT and AL122023.1 in the prostate and exposes xCT as a potential marker or therapeutic target in high-risk prostate cancer.…”
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25816
Surface defect detection on industrial drum rollers: Using enhanced YOLOv8n and structured light for accurate inspection.
Published 2025-01-01“…Then, a new feature fusion module was proposed to enable the fusion network to learn additional original information. Finally, Wise-IoU was applied to replace CIoU in the loss function, so that the network pays more attention to the high-quality samples. …”
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25817
Influence of the Methane–Zeolite a Interaction Potential on the Concentration Dependence of Self-Diffusivity
Published 2011-06-01“…Here, we compute the variation of the self-diffusivity (D) with loading (c) for these two types of potentials and show that this slight variation in the diameter changes the concentration dependence qualitatively: thus, D decreases monotonically with c for model A, while D increases and goes through a maximum before finally decreasing for model B. This effect and the surprising congruence of the diffusion coefficients for both models at high loadings is examined in detail at the molecular level. …”
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25818
Application of Photovoltaic Systems in Field Observation and Research Stations: Research on the Relationship between Power Generation Scale and Electricity Consumption to Improve P...
Published 2023-01-01“…The design scheme and scale of PV power generation systems suitable for field observation stations were determined. Finally, a PV power generation test system was set up, and PV power generation data were sorted out. …”
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25819
Optimization of the heat transfer efficiency of a ground source heat pump heating system via FLUENT numerical simulation with fluid–solid coupling
Published 2025-01-01“…Sensitivity analysis shows that soil thermal conductivity has the greatest impact on the heat transfer efficiency, followed by the U-tube length, U-tube diameter, and finally, the circulating water flow rate. In conclusion, a comprehensive optimization scheme is proposed, including the use of additive-modified circulating water solution to increase the heat transfer capacity, optimization of the design of U-tubes to improve the heat transfer area, improvement of soil conditions to improve thermal conductivity, and adjustment of the circulating water flow rate to achieve the optimal flow state. …”
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25820
Transcriptomic and proteomic profiling identifies feline fibrosarcoma as clinically amenable model for aggressive sarcoma subtypes
Published 2025-02-01“…Significant enrichment in DNA repair pathways in feline FSA correlate with aggressive clinical behavior in human soft-tissue sarcoma. Finally, we leverage the molecular profiles to identify vulnerabilities, including sensitivity to ATR and PARP inhibition as potential treatment for feline FSA. …”
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