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25561
Multi-tissue network analysis reveals the effect of JNK inhibition on dietary sucrose-induced metabolic dysfunction in rats
Published 2025-02-01“…The c-Jun N-terminal kinase (JNK) pathway plays a crucial role in response to dietary stressors, and it was demonstrated that the inhibition of the JNK pathway could potentially be used in the treatment of MAFLD. …”
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25562
Review of design and manufacturing of superabsorbent polymers (SAPs) hydrogel for agriculture in arid areas
Published 2024-09-01“…Second, SAPs are prepared by mixing the monomer solution and crosslinking agent and converting the SAP solution into fibers using an electrospinning machine and wet spinning technique. Finally, the sheet was produced using a spun lace (hydroentangling) machine that converts SAP fibers into sheets. …”
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25563
CAR-T CELL THERAPY IN B-CELL ACUTE LYMPHOBLASTIC LEUKEMIA
Published 2024-01-01“…For B-ALL patients who relapse early after allo-HSCT or those with insufficient T-cell numbers for an autologous approach, using T cells from the original stem cell donor offers the opportunity for the successful generation of CAR-T cells and for an effective therapeutic approach. Finally, recent studies have introduced allogeneic CAR-T cells generated from healthy donors or unmatched, which are opportunely manipulated with gene editing to reduce the risk of immunological incompatibility, with promising therapeutic effects. …”
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25564
Los ADPIC y el TLCAN en la industria farmacéutica mexicana: Un análisis TradeCAN
Published 2011-01-01“…El trabajo muestra el deterioro de la industria farmacéutica mexicana, lo mismo de insumos que de productos finales, en los ámbitos comercial, de competitividad y de actividad inventiva - producción de conocimiento patentado - a principios de la década de los noventa. …”
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25565
Investigating Changes in the Water Requirement of Agricultural Crops in the Jiroft Plain Under Climate Change Impact
Published 2023-09-01“…Then, using HadGEM2 model, these variables were simulated during 2050-2031 based on RCP2.6, RCP4.5 and RCP8.5 scenarios. Finally, by calculating the amount of effective precipitation and potential evapotranspiration, the amount of net irrigation requirement of the studied crops was estimated on a monthly scale in the base and the future period, and their changes were evaluated in comparison with each other. …”
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25566
Innovation Tourism Information System to Support Post-Covid-19 Health Protocols and Halal Tour in The Special Area of Yogyakarta
Published 2023-08-01“…In addition, it will also determine the characteristics of the Tourism Information System needed by Stakeholders in order to be able to support the implementation of the Covid-19 Health Protocol in the "New Normal" era and the implementation of Halal Tourism as a promising option. And finally in this research will also provide a proposal for a prototype / Information System Innovation that can be used and replicated by stakeholders in the Tourism sector, especially in DI Keyword : ProtocolHealth, Covid-19 Pandemic, Halal Tourism, Tourism Information System…”
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25567
FFDL: Feature Fusion-Based Deep Learning Method Utilizing Federated Learning for Forged Face Detection
Published 2025-01-01“…The experiments were carried out with publicly available datasets and involved changing several parameters. Finally, the proposed model’s performance was compared with other deep learning models within federated learning environments to identify forgeries. …”
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25568
Identification of genes involved in energy metabolism in preeclampsia and discovery of early biomarkers
Published 2025-02-01“…Key differentially expressed genes included CRH(Corticotropin-Releasing Hormone), LEP(Leptin), PDK4(Pyruvate Dehydrogenase Kinase Isozyme 4), SPP1(Secreted Phosphoprotein 1), and SST(Somatostatin). …”
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25569
Spatial and Temporal Characteristics of Rurality in Urban Suburb Town and Its Driving Factors Based on Land Use Transformation
Published 2020-01-01“…Taking 25 towns in Lixia County and Shanghe County in Jinan city as the study area and using land use data and economic statistics data, the rurality evaluation system based on the land use transformation was constructed, the changes of the rurality index and intensity from 2009 to 2015 were calculated, and the driving factors of the rurality were analyzed. …”
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25570
El Finlay de Albaijés
Published 2021-01-01“…Se utilizó el método iconográfico y el iconológico, fundamentados con una revisión bibliográfica sobre la vida del médico cubano y su actividad investigativa que lo convirtió en eminente hombre de ciencia, capaz de elaborar a finales del siglo XIX, una avanzada teoría sobre el modo de contagio y de propagación de la fiebre amarilla, comprobada experimentalmente y llevada a la práctica, lo cual contribuyó a salvar numerosas vidas en Cuba y en otras áreas del continente. …”
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25571
Multistrategy Harris Hawks Optimization Algorithm Using Chaotic Method, Cauchy Mutation, and Elite Individual Guidance
Published 2022-01-01“…Fourth, the local optimization ability of the algorithm by using the ergodicity of the chaotic system in the exploitation phase to perform a chaotic local search for the optimal individual is enhanced, which can effectively jump out after the algorithm falls into the local optimum. Finally, we use the elite individuals of the population to guide the position update of the population’s individuals, fully communicate with the dominant individuals, and speed up the convergence speed of the algorithm. …”
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25572
Edge Computing-Based Machine Vision for Non-Invasive and Rapid Soft Sensing of Mushroom Liquid Strain Biomass
Published 2025-01-01“…The cascaded machine vision model mainly consists of three steps: first, the object detection task to locate the observation window, achieving a mean Average Precision (mAP50:95) of 82.3% with 78.7 GFLOPs; then, the segmentation task to extract liquid strain data within the observation window, yielding a mean intersection over union (MIoU) of 85.9% with 110.4 GFLOPs; and finally, calculating mycelium biomass indices via the morphological image processing task. …”
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25573
Blockchain based adaptive federated learning in computational power network
Published 2024-06-01“…Concurrently, an adaptive weight aggregation algorithm was designed to alleviate the decrease in model performance and stability caused by differences in data quality, thereby improving the accuracy of the model and accelerating model convergence. Finally, the integration of blockchain technology strengthened the security mechanism, effectively preventing poisoning attacks and inference attacks. …”
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25574
Prevalence of depression in visually impaired children and adolescents: A systematic review and meta-analysis
Published 2023-04-01“…Heterogeneity was assessed using I2 to explain heterogeneity meta-regressive analysis and subgroup analyses were done. With the finally selected 13 studies consisting of 822 participants, the overall pooled prevalence of depression or dysthymia among visually impaired children or adolescents was 14% (137/822 individuals, 95% CI = 9% to 20%), with high heterogeneity between studies (I2 = 80.11%; P < 0.001). …”
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25575
Peptidoglycan recognition protein PGRP-5 is involved in immune defence and neuro-behavioral disorders in zebrafish embryos.
Published 2025-01-01“…On the other hand, the locomotor behavior abilities and the antioxidant enzyme activities such as CAT and SOD were obviously decreased under the DrPGRP-5 KD conditions. Finally, incubation of zebrafish embryos with anti-inflammatory and neuroprotective agents (10 μM Minocycline) can partially rescue the DrPGRP5-regulated locomotor behavior. …”
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25576
L’évaluation pré/post des effets de la communication du risque sur la perception du risque : l'exemple de la pêche sportive dans le Saint-Laurent autour de Montréal
Published 2003-05-01“…Moreover, the type (negative/positive) and the amplitude (strong/weak) of the opinion changes varied unequally with each indicator used. Finally, among those respondants that had changed their opinion between the pre-test and the post-test, part of these again changed their opinion between the post-test and the follow-up; this suggests that the effects of risk communication on risk perception might be somewhat volatile. …”
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25577
To Be or Not To Be: Twitter Presence among Turkish Diplomats
Published 2022-07-01“…Online activities of different state institutions are not synchronized for efficient use of social media and so-called twiplomacy. Finally, according to the results of the content analysis, Turkish diplomats usually employ positive language in their tweets, as seen by the most frequently used terms, related emotions, and sentiment scores. …”
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25578
Evaluation of Laundry Units in Teaching Hospitals of Tehran University of Medical Sciences and Recommendations for Performance Enhancement
Published 2024-05-01“…These criteria were then weighted using the Step-wise Weight Assessment Ratio Analysis (SWARA) method. Finally, hospitals were ranked using the VIseKriterijumska Optimizacija I Kompromisno Resenje (VIKOR) method. …”
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25579
Paisagem geográfica: muito além do nosso campo de visão
Published 2018-12-01“…However, many aspects within the frame may be derived from aspects or objects that are out of the frame. Finally, going a little further, many unseen aspects can be inferred by some visible objects. …”
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25580
Gut microbiota and quantitative traits divergence at different altitude of long-tailed dwarf hamsters, Cricetulus longicaudatus
Published 2025-01-01“…And Providencia had significant correlation with body size. Finally, functional analysis of the gut microbiota showed changes in metabolic function that depended on elevation, and collinear network analysis showed how the gut microbiota interacts with each other. …”
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