CDK9 Expression Shows Role as a Potential Prognostic Biomarker in Breast Cancer Patients Who Fail to Achieve Pathologic Complete Response after Neoadjuvant Chemotherapy by Ashley J. Schlafstein, Allison E. Withers, Soumon Rudra, Diana Danelia, Jeffrey M. Switchenko, Donna Mister, Saul Harari, Hui Zhang, Waaqo Daddacha, Shahrzad Ehdaivand, Xiaoxian Li, Mylin A. Torres, David S. Yu

“…However, prognostic biomarkers for clinical outcome are unclear in this patient population. Cyclin-dependent kinase 9 (CDK9) is often dysregulated in breast cancer, and its deficiency results in genomic instability. …”
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Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent by Korfmann, Kevin, Sellinger, Thibaut Paul Patrick, Freund, Fabian, Fumagalli, Matteo, Tellier, Aurélien

“…Secondly, we show that our approaches can also recover the effect of positive selective sweeps along the genome. Finally, we are able to distinguish skewed offspring distribution from selection while simultaneously inferring the past variation of population size. …”
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Slaying axion-like particles via gravitational waves and primordial black holes from supercooled phase transition by Angela Conaci, Luigi Delle Rose, P. S. Bhupal Dev, Anish Ghoshal

“…Moreover, the supercooled PT leads to a potentially observable stochastic gravitational wave (GW) signal at future GW observatories, such as aLIGO, LISA and ET, that acts as another complementary probe of the ALPs, as well as of the PBH dark matter. Finally, we show that the recent NANOGrav signal of stochastic GW in the nHz frequency range can be explained in our model with f a ≃ (0.1 GeV − 1 TeV).…”
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Short-Term Investigation into the Effect of the Traffic Farming Systems on the Soil Physical Behavior of an Arable Land by Kasem M. M. AL-Halfi, John McL. Bennett

“…The results showed that switching from the RTF to the CTF system reduced the soil' BD by 6.85 %, reduced the soil CI by 16.55 % and increased the soil MC by 32.31 %. Finally, the graphic curves reflected the stability and consistency of the CTF system soil's physical behavior with increasing depth compared to the RTF system soil's physical behavior which fluctuated and disturbed for the same studied depth and under the same climatic conditions and traditional farming practices.…”
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Towards an unbiased jet energy loss measurement by Liliana Apolinário, Lénea Luís, José Guilherme Milhano, João M. Silva

“…Additionally, we compare Q AA to an experimentally proposed proxy for fractional jet energy loss, S loss , showing that both quantities are similar, although the former provides a more clear physical interpretation. Finally, we show the size of the p T migration correction for four different substructure observables and how to reliably use the quantile procedure experimentally to improve existing measurements.…”
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RIPK1 expression and inhibition in tauopathies: implications for neuroinflammation and neuroprotection by Ignacio Silva-Llanes, Ignacio Silva-Llanes, Ignacio Silva-Llanes, Enrique Madruga, Enrique Madruga, Ana Martínez, Ana Martínez, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker, Isabel Lastres-Becker

“…Apart from the neurodegenerative process, tauopathies are also characterized by a chronic low-grade neuroinflammation process, where the receptor-interacting protein kinase 1 (RIPK1) protein plays an essential role. …”
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Semantic-Aware Top-k Multirequest Optimal Route by Shuang Wang, Yingchun Xu, Yinzhe Wang, Hezhi Liu, Qiaoqiao Zhang, Tiemin Ma, Shengnan Liu, Siyuan Zhang, Anliang Li

“…We use an efficient label indexing technique for the shortest path queries to further improve efficiency. Finally, we perform an extensive experimental evaluation on multiple real-world graphs to demonstrate that the proposed methods deliver excellent performance.…”
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On the Regional Variability of dB/dt and Its Significance to GIC by A. P. Dimmock, L. Rosenqvist, D. T. Welling, A. Viljanen, I. Honkonen, R. J. Boynton, E. Yordanova

“…The dependency between regional variability, solar wind conditions, and geomagnetic indices are also investigated. …”
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Grey Relational Entropy Calculation and Fractional Prediction of Water and Economy in the Beijing-Tianjin-Hebei Region by Lifeng Wu, Xiaorui Guo, Yan Chen

“…First, use the grey correlation entropy method to calculate the existing data to explore the relationship between the two systems, then use the FGM(1, 1) model to predict the grey correlation entropy value of Beijing-Tianjin-Hebei in 2020–2024, and finally, calculate the entropy difference of the grey relation entropy for the region from 2015 to 2024. …”
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Design Techniques for Single-Ended Wireline Crosstalk Cancellation Receiver Up To 112 Gb/s by Liping Zhong, Quan Pan

“…Additionally, the increased bandwidth demands lead to higher power consumption. Finally, as frequency increases, the channel exhibits severe insertion loss, intensifying the equalization burden on receivers. …”
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Pulmonary enteric adenocarcinoma with progression disease after second - line therapy: a case report by Ya Guo, Bin Zhang, Heng Zhang, Yunbin Gao, Haibo Zhao, Pei Jiang, Qing-Qing Yu

“…Anlotinib targeted drugs were selected for third-line treatment, but considering the overall poor condition of the patient, the patient himself refused further treatment. Finally, after discharge, the patient went to the local hospital for nutritional support and symptomatic treatment. …”
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Simulation study on converter transformer windings stress characteristics under harmonic current and temperature rise effect by Jing Xu, Jian Hao, Ning Zhang, Ruijin Liao, Yun Feng, Wenlong Liao, Huanchao Cheng

Subjects: “…Transformer windings…”
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Identifying and ranking the effective financial factors on rural entrepreneurial small businesses by Khosro Farahi, Parvaneh Gelard, Hamid Tohidi

“…The results indicate a positive and significant effect of rural population ratio, financing through financial institutions, economic growth, openness rate in business space, gender composition, and inflation rate in agriculture sectors, as well as a significant reverse effect of official employment rate, job-seeking population ratio, exchange rate uncertainty, government employment rate and graduation ratio on entrepreneurship in both service and agriculture sectors. Finally, the results of the Friedman test showed that the financing factor through financial institutions has the highest average rating due to the bank-oriented financial resources of entrepreneurial enterprises in the rural service and agriculture sectors. …”
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Adaptive cognitive control in 4 to 7-year-old children and potential effects of school-based yoga-mindfulness interventions: an exploratory study in Italy by Lisa Toffoli, Giulia Stefanelli, Giulia Manca, Fiorella Del Popolo Cristaldi, Gian Marco Duma, Michele Guidi, Francesca Incagli, Luca Sbernini, Luca Sbernini, Vincenza Tarantino, Giovanni Mento, Giovanni Mento

“…Moreover, they successfully modulate interference control as a function of environmental contingencies, displaying more optimal conflict resolution when proactive control is engaged. Finally, we observed a post-intervention increase of the capability to implicitly adapt motor preparation/inhibition and a boosting effect on the interference control functions.DiscussionOverall, these findings confirmed that adaptive CC is already present in preschool-aged children, extending these results to include 4-years-olds. …”
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La santé et la sécurité au travail des travailleurs immigrants à Montréal : résultats d’une enquête exploratoire by Sylvie Gravel, Laurence Boucheron, Michel Kane

“…Moreover, the survey enabled us to outline the various viewpoints contributing to an analysis of the workers’ needs ; these contradictory viewpoints emerged not only from occupational health and safety agencies, but also from unions and community groups. Finally, the study allowed us to determine the pertinence of continuing our work on the factors that facilitate and limit access to compensation for immigrant workers who have suffered work injuries.…”
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Development and validity test of impression management efficacy scale based on self-presentation behavior of Chinese youth on social media by Yixuan Liu, Ke Lei

“…The collected data underwent repeated testing to refine and finalize the questionnaire.ResultsThis study explores the relationship between self-presentation and IME in social media contexts. …”
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Aggressive Differentiated Thyroid Cancer due to EML4e13-ALKe20 Fusion: A Case Presentation and Review of the Literature by Rodhan Khthir, Zainab Shaheen, Prasanna Santhanam, Saroj Sigdel

“…We describe a case of a 30-year-old man with a locally aggressive form of papillary thyroid cancer with EML4e13-ALKe20 fusion (EML4: echinoderm microtubule-associated protein-like 4; ALK: anaplastic lymphoma kinase). He presented with right-side cervical lymphadenopathy with a highly suspicious right-side thyroid nodule. …”
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Particle Swarm Optimization-Based Content Delivery Protocol for UAV VAENTs by Yongje Shin, Hyun-Seok Choi, Youngju Nam, Euisin Lee

“…Furthermore, by utilizing UAVs, we address the physical disconnectivity issues that arise during data transmission in VANETs, thereby minimizing the delay and maximizing the total data rate under realistic conditions. Finally, extensive simulations are conducted to validate the superiority of the proposed protocol in various circumstances in an NS-3 simulation. …”
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Mitochondria-Targeted Biomaterials-Regulating Macrophage Polarization Opens New Perspectives for Disease Treatment by Tian Z, Wang X, Chen S, Guo Z, Di J, Xiang C

“…This review highlights the critical role of mitochondrial function in macrophage polarization and discusses therapeutic strategies mediated by biomaterials, including mitochondria-targeted biomaterials. Finally, the prospects and challenges of the use of these biomaterials in disease modulation have been explored, emphasizing their potential to be translated to the clinic. …”
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Environmental design studies on perception and simulation: an urban design approach by Barbara Piga, Eugenio Morello

“…From a methodological point of view, we explored the topic through two main tasks, namely the selection and reconstruction of the research context and the key issues of perceptual simulation finalized in the second task, i.e. the construction of a set of simulation tools for urban design, intended as a matrix of possible practical applications. …”
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