Magnetic Resonance Imaging Visualization of Vulnerable Atherosclerotic Plaques at the Brachiocephalic Artery of Apolipoprotein E Knockout Mice by the Blood-Pool Contrast Agent B229... by Cinzia Parolini, Marco Busnelli, Giulia S. Ganzetti, Federica Dellera, Stefano Manzini, Eugenio Scanziani, Jason L. Johnson, Cesare R. Sirtori, Giulia Chiesa

“…Signal enhancement and plaque to muscle contrast values correlated with macrophage content 40 minutes after contrast agent administration ( p < .01). Finally, 70 minutes after B22956/1 infusion, plaque to muscle contrast significantly correlated with the percentage of stenosis ( p < .005). …”
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Global progress in competitive co-evolution: a systematic comparison of alternative methods by Stefano Nolfi, Paolo Pagliuca

“…We discuss the factors that facilitate genuine progress. Finally, we compare the efficacy of four qualitatively different algorithms, including two newly introduced methods. …”
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Nonprofessional Phagocytosis Can Facilitate Herpesvirus Entry into Ocular Cells by Vaibhav Tiwari, Deepak Shukla

“…Similar inhibition was seen by blocking phosphoinositide 3 kinase signaling, which is required for microbial phagocytosis. …”
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Symptom-based depression subtypes: brain dynamic specificity and its association with gene expression profiles by Qunjun Liang, Zhifeng Zhou, Shengli Chen, Shiwei Lin, Xiaoshan Lin, Ying Li, Yingli Zhang, Bo Peng, Gangqiang Hou, Yingwei Qiu

“…The loading weight in CCA showed that dynamics in transmodal networks contributed the most to the correlation in the subtypes characterized by typical depression symptoms, whereas unimodal networks contributed the most to subtypes characterized by anxiety and insomnia. Finally, gene expression underlying the CCA model, along with its biological encoding process, performed using a postmortem gene expression atlas revealed distinct gene enrichments for different subtypes. …”
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Study on Inhibitory Effect of Cavity on Gas Explosion Propagation by Zhuo Yan, Shujie Yuan, Zhongqing Li, Shicheng Gu, Chaomin Mu

“…The dual cavity further improves the suppression performance and attenuates the shock wave overpressure by 28.88%. Finally, by simulating the propagation process of the gas explosion shock wave and flame in the cavity, the mechanism of inhibiting gas explosion propagation by the cavity structure is analyzed.…”
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Empowering Security Operation Center With Artificial Intelligence and Machine Learning&#x2014;A Systematic Literature Review by Mohamad Khayat, Ezedin Barka, Mohamed Adel Serhani, Farag Sallabi, Khaled Shuaib, Heba M. Khater

“…Moreover, this systematic review emphasizes the benefits of these technologies for enhancing security operations. Finally, a case study is presented to describe the function of ML- and AI-powered SOC components to achieve optimum security. …”
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Comprehensive evaluation of pure and hybrid collaborative filtering in drug repurposing by Clémence Réda, Jill-Jênn Vie, Olaf Wolkenhauer

“…Moreover, in drug repurposing, the ability of a model to extrapolate beyond its training distribution is crucial and should also be assessed. Finally, we identified a subcategory of collaborative filtering that seems efficient and robust to distribution shifts. …”
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Post-burns persistent inflammation leads to kidney PANoptosis with Caspases pathway activation by Guang Yang, Minghui Wang, Mulan Qahar, Jinqing He, Zhiwei Lai, Sanmu Li, Dehua He, Xuefei Yan, Zuying Xiong, Zibo Xiong, Thu H. Le

“…Subsequently, the investigation focused on assessing the effects of activated macrophages on podocytes. Finally, the study evaluated the effectiveness of dexamethasone in mitigating the impacts of burns on the kidneys. …”
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Berberine-induced browning and energy metabolism: mechanisms and implications by Aslıhan Alpaslan Ağaçdiken, Zeynep Göktaş

“…While the precise mechanisms behind this effect remain unclear, the adenosine monophosphate-activated protein kinase (AMPK) pathway is known to play a crucial role. …”
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KLF9-GRK5-HDAC6 axis aggravates osteoarthritis pathogenesis by promoting chondrocyte extracellular matrix degradation and apoptosis by Xiaonan Zhou, Peng Jiang, Huangqi Tan, Yanfang Wang, Lunhao Bai

“…KLF9 mediated the transcription of G protein-coupled receptor kinase 5 (GRK5) by directly targeting the GRK5 promoter. …”
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Triglycerides mediate the relationships of per- and poly-fluoroalkyl substance (PFAS) exposure with nonalcoholic fatty liver disease (NAFLD) risk in US participants by Wenying Qiao, Jiashuo Li, Lijia Luo, Wenjuan Peng, Xi Wang, Ronghua Jin, Junnan Li

“…It further highlighted significant mediation effects of TG, with the mediated proportion ranging from 10.4 % to 42.9 %. Finally, sensitivity and stratified analyses were performed, confirming the reliability of these findings. …”
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Insulin-Like Growth Factor I Prevents Cellular Aging via Activation of Mitophagy by Xuwei Hou, Zhaohui Li, Yusuke Higashi, Patrice Delafontaine, Sergiy Sukhanov

“…IGF-1 increased mitophagy in aged cells, and this was associated with decreased expression of cyclin-dependent kinase inhibitors p16 and p21 and elevated levels of Nrf2 and Sirt3, regulators of mitophagy and mitochondrial biogenesis. …”
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Latent profile analysis and influence factors study of nurses’ job performance by Zhenfan Liu, Xiaoting Yan, Guifang Xie, Jing Lu, Zhitong Wang, Cui Chen, Jijun Wu, Wei Qing

“…Latent profile analysis of nurses’ job performance were analyzed, and logistic regression was used to analyze the factors influencing different categories of nurses’ job performance.Results390 nurses were finally included. Nurses job performance score was (45.05 ± 6.55). …”
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Identification and prioritization of factors affecting the saffron supply chain and selection strategies during the pandemic crisis based on the ANP-SWOT method by Farshid Riahi Dorcheh, Misagh Rahbari

“…Subsequently, the weights of the criteria, sub-criteria, and priorities of the presented strategies are computed using the AHP-SWOT and ANP-SWOT methods. Finally, data were acquired through the systematic collection of expert opinions using the Delphi method.FindingsAccording to the prioritization of saffron export development strategies during the COVID-19 pandemic based on the AHP-SWOT method, “Performing marketing research in universities” and “Creating international associations and using anti-COVID-19 tools” were identified as the most important strategies. …”
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Modeling dynamic changes in type 1 diabetes progression:Quantifying $\beta$-cell variation after the appearance ofislet-specific autoimmune responses by Patrick Nelson, Noah Smith, Stanca Ciupe, Weiping Zou, Gilbert S. Omenn, Massimo Pietropaolo

“…Our model is able to describe changes in the ratio of pathogenic T cells and regulatory T cells after the appearance of islet antibodies in the pancreas. Finally, we discuss the robustness of the model and its ability to assist experimentalists in designing studies to test complicated theories about the disease.…”
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Generation of barcoded plasmid libraries for massively parallel analysis of chromatin position effects by M. O. Lebedev, L. A. Yarinich, A. V. Ivankin, A. V. Pindyurin

“…We also compare different approaches to check the quality of barcoded plasmid libraries. Finally, we briefly describe alternative approaches that can be used for the generation of such libraries. …”
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İlköğretim Okulu Müdür ve Öğretmenlerinin Velilere İlişkin Algılarının Analizi by Ali Ünal, Atila Yıldırım, Methi Çelik

“…Katılımcılar tarafından üretilen metaforlar, açıklamalarıda dikkate alınarak; koruyucu, finans kaynağı, patron, kusur arayan, çıkarcı, hayalperest, gelişmeye açık, bilinçsiz ve ilgisiz veli olmak üzere 9 temaya ayrılmıştır. …”
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Security protection method based on mimic defense and Paillier encryption for smart IoT terminals by GU Tiansheng, ZENG Fukang, SHAO Sisi, NIE Yijun, JI Zongkai, ZHENG Yulu, SHI Yuchen, LIU Shangdong, JI Yimu

“…It also effectively supported the efficient and reliable transmission of data of the intelligent IoT devices. Finally, taking the mimic smart IoT system as an application scenario, the proposed method was theoretically analyzed and experimentally validated for its improved performance and security.…”
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Drug repurposing screen for the rare disease ataxia-telangiectasia by Namrata Jayanth, Gurvan Mahé, Matthew Campbell, Mike Lipkin, Shushant Jain, Rhea van de Bospoort, Jennifer Thornton, Brad Margus, David F. Fischer

“…It is caused by bi-allelic mutations impacting a gene encoding a serine/threonine kinase ATM (Ataxia Telangiectasia Mutated), which plays a crucial role in DNA repair and maintenance of genomic stability. …”
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The Spiralling of Corporate Corruption and the Plummeting of Corporate Governance and Ethical Leadership in African Institutions by Hlalele Matebese

“…Competent and ethical leaders, on the other hand, resist corruption; African leaders and authorities should take steps to fight corruption through ethics and governance; African corporations have become increasingly corrupt; corporate governance and ethical leadership have declined in Africa; African politicians have uncurbed power to advance their private gains, and finally, African leaders need to change their mindsets and cultures to achieve economic growth. …”
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